Hu lai Wei

Summary

Affiliation: Lanzhou Veterinary Research Institute
Country: China

Publications

  1. ncbi Sensitization and apoptosis augmentation of K562/ADM cells by anti-multidrug resistance gene peptide nucleic acid and antisense oligodeoxyribonucleotide
    Hu lai Wei
    Laboratory Center for Medical Science, Lanzhou Medical College, Lanzhou 730000, China
    Acta Pharmacol Sin 24:805-11. 2003
  2. ncbi Arsenic trioxide inhibits p-glycoprotein expression in multidrug-resistant human leukemia cells that overexpress the MDR1 gene
    Hulai Wei
    Laboratory Center for Medical Science, Lanzhou Medical College, Lanzhou 730000, China
    Chin Med J (Engl) 116:1644-8. 2003
  3. ncbi [The relationship between multi-drug resistance and proportion of leukemia stem cells and expression of drug transporters in drug-resistant leukemia K562/ADM cells]
    Juan Yi
    Laboratory Center for Medical Science, School of Medicine, Lanzhou University, Lanzhou, China
    Zhonghua Yi Xue Za Zhi 89:1741-4. 2009
  4. ncbi [siRNA silences mdr1 gene expression and reverses apoptosis resistance of K562/ADM cells line]
    Hu lai Wei
    Laboratory Center for Medical Science, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, Lanzhou University, Lanzhou 730000, China
    Zhonghua Xue Ye Xue Za Zhi 28:388-90. 2007
  5. ncbi [Arsenic trioxide inhibits P-glycoprotein expression in multidrug-resistant human leukemia K562/ADM cell line that overexpresses mdr-1 gene and enhances their chemotherapeutic sensitivity]
    Hu-Lai Wei
    Laboratory Center for Medical Science, Lanzhou Medical College, Lanzhou 730000, China
    Zhonghua Xue Ye Xue Za Zhi 24:28-31. 2003
  6. ncbi Arsenic trioxide overcomes apoptosis inhibition in K562/ADM cells by regulating vital components in apoptotic pathway
    Dong-hai Wang
    Molecular Cell Biology Research Center, Key Laboratory of Preclinical Study for Drugs of Gansu Province, Lanzhou University School of Medicine, Lanzhou 730000, PR China
    Pharmacol Res 52:376-85. 2005
  7. ncbi The crystal structures of copper(II), manganese(II), and nickel(II) complexes of a (Z)-2-hydroxy-N'-(2-oxoindolin-3-ylidene) benzohydrazide--potential antitumor agents
    Xia Zhong
    College of Chemistry and Chemical Engineering and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China
    Bioorg Med Chem Lett 17:3774-7. 2007

Collaborators

  • Juan Yi
  • Xia Zhong
  • Dong-hai Wang
  • Xing Wang
  • Da Qi Wang
  • Da-Qi Wang
  • Wei-Sheng Liu
  • Wei Sheng Liu
  • Huai-Shun Zhao
  • Zhi-Hui Min
  • Jian-min Liu
  • Chun-Yan Hao

Detail Information

Publications7

  1. ncbi Sensitization and apoptosis augmentation of K562/ADM cells by anti-multidrug resistance gene peptide nucleic acid and antisense oligodeoxyribonucleotide
    Hu lai Wei
    Laboratory Center for Medical Science, Lanzhou Medical College, Lanzhou 730000, China
    Acta Pharmacol Sin 24:805-11. 2003
    ..To investigate the reversal effect and apoptosis enhancement of peptide nucleic acid (PNA) and antisense oligodeoxyribonucleotide (ASODN) targeted to multidrug resistance gene (mdr1) on human multidrug resistant leukemia K562/ADM cells...
  2. ncbi Arsenic trioxide inhibits p-glycoprotein expression in multidrug-resistant human leukemia cells that overexpress the MDR1 gene
    Hulai Wei
    Laboratory Center for Medical Science, Lanzhou Medical College, Lanzhou 730000, China
    Chin Med J (Engl) 116:1644-8. 2003
    ..To investigate the effects of arsenic trioxide (As(2)O(3)) on the apoptosis and p-glycoprotein (P-gp) expression of multidrug-resistant human leukemia cells...
  3. ncbi [The relationship between multi-drug resistance and proportion of leukemia stem cells and expression of drug transporters in drug-resistant leukemia K562/ADM cells]
    Juan Yi
    Laboratory Center for Medical Science, School of Medicine, Lanzhou University, Lanzhou, China
    Zhonghua Yi Xue Za Zhi 89:1741-4. 2009
    ..To investigate the drug resistance, proportion of leukemia stem cells (LSC) and expression of P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) in drug-sensitive and multidrug-resistant leukemia cell population...
  4. ncbi [siRNA silences mdr1 gene expression and reverses apoptosis resistance of K562/ADM cells line]
    Hu lai Wei
    Laboratory Center for Medical Science, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, Lanzhou University, Lanzhou 730000, China
    Zhonghua Xue Ye Xue Za Zhi 28:388-90. 2007
    ..To explore the effect of small interfering RNA(siRNA) on silence of mdr1 gene and reversal of apoptosis resistance in multidrug-resistant (MDR) human leukemia K562/ADM cell...
  5. ncbi [Arsenic trioxide inhibits P-glycoprotein expression in multidrug-resistant human leukemia K562/ADM cell line that overexpresses mdr-1 gene and enhances their chemotherapeutic sensitivity]
    Hu-Lai Wei
    Laboratory Center for Medical Science, Lanzhou Medical College, Lanzhou 730000, China
    Zhonghua Xue Ye Xue Za Zhi 24:28-31. 2003
    ....
  6. ncbi Arsenic trioxide overcomes apoptosis inhibition in K562/ADM cells by regulating vital components in apoptotic pathway
    Dong-hai Wang
    Molecular Cell Biology Research Center, Key Laboratory of Preclinical Study for Drugs of Gansu Province, Lanzhou University School of Medicine, Lanzhou 730000, PR China
    Pharmacol Res 52:376-85. 2005
    ..Taken together, As(2)O(3) is able to reverse the apoptosis resistance in drug-resistant K562/ADM cells by modulating expression or activity of key factors associated with apoptosis induction...
  7. ncbi The crystal structures of copper(II), manganese(II), and nickel(II) complexes of a (Z)-2-hydroxy-N'-(2-oxoindolin-3-ylidene) benzohydrazide--potential antitumor agents
    Xia Zhong
    College of Chemistry and Chemical Engineering and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China
    Bioorg Med Chem Lett 17:3774-7. 2007
    ..The complexes have been structurally characterized by X-ray crystallography. Among the three complexes, the Cu(II) complex had the novel highest antitumor activity...