Hu lai Wei

Summary

Affiliation: Lanzhou Veterinary Research Institute
Country: China

Publications

  1. ncbi request reprint Sensitization and apoptosis augmentation of K562/ADM cells by anti-multidrug resistance gene peptide nucleic acid and antisense oligodeoxyribonucleotide
    Hu lai Wei
    Laboratory Center for Medical Science, Lanzhou Medical College, Lanzhou 730000, China
    Acta Pharmacol Sin 24:805-11. 2003
  2. ncbi request reprint Arsenic trioxide inhibits p-glycoprotein expression in multidrug-resistant human leukemia cells that overexpress the MDR1 gene
    Hulai Wei
    Laboratory Center for Medical Science, Lanzhou Medical College, Lanzhou 730000, China
    Chin Med J (Engl) 116:1644-8. 2003
  3. ncbi request reprint [Arsenic trioxide inhibits P-glycoprotein expression in multidrug-resistant human leukemia K562/ADM cell line that overexpresses mdr-1 gene and enhances their chemotherapeutic sensitivity]
    Hu lai Wei
    Laboratory Center for Medical Science, Lanzhou Medical College, Lanzhou 730000, China
    Zhonghua Xue Ye Xue Za Zhi 24:28-31. 2003
  4. ncbi request reprint [The relationship between multi-drug resistance and proportion of leukemia stem cells and expression of drug transporters in drug-resistant leukemia K562/ADM cells]
    Juan Yi
    Laboratory Center for Medical Science, School of Medicine, Lanzhou University, Lanzhou, China
    Zhonghua Yi Xue Za Zhi 89:1741-4. 2009
  5. ncbi request reprint [siRNA silences mdr1 gene expression and reverses apoptosis resistance of K562/ADM cells line]
    Hu lai Wei
    Laboratory Center for Medical Science, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, Lanzhou University, Lanzhou 730000, China
    Zhonghua Xue Ye Xue Za Zhi 28:388-90. 2007
  6. ncbi request reprint Arsenic trioxide overcomes apoptosis inhibition in K562/ADM cells by regulating vital components in apoptotic pathway
    Dong Hai Wang
    Molecular Cell Biology Research Center, Key Laboratory of Preclinical Study for Drugs of Gansu Province, Lanzhou University School of Medicine, Lanzhou 730000, PR China
    Pharmacol Res 52:376-85. 2005
  7. ncbi request reprint The crystal structures of copper(II), manganese(II), and nickel(II) complexes of a (Z)-2-hydroxy-N'-(2-oxoindolin-3-ylidene) benzohydrazide--potential antitumor agents
    Xia Zhong
    College of Chemistry and Chemical Engineering and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China
    Bioorg Med Chem Lett 17:3774-7. 2007

Collaborators

  • Juan Yi
  • Xia Zhong
  • Dong Hai Wang
  • Da Qi Wang
  • Xing Wang
  • Wei Sheng Liu
  • Jian min Liu
  • Huai shun Zhao
  • Chun Yan Hao
  • Zhi Hui Min

Detail Information

Publications7

  1. ncbi request reprint Sensitization and apoptosis augmentation of K562/ADM cells by anti-multidrug resistance gene peptide nucleic acid and antisense oligodeoxyribonucleotide
    Hu lai Wei
    Laboratory Center for Medical Science, Lanzhou Medical College, Lanzhou 730000, China
    Acta Pharmacol Sin 24:805-11. 2003
    ..To investigate the reversal effect and apoptosis enhancement of peptide nucleic acid (PNA) and antisense oligodeoxyribonucleotide (ASODN) targeted to multidrug resistance gene (mdr1) on human multidrug resistant leukemia K562/ADM cells...
  2. ncbi request reprint Arsenic trioxide inhibits p-glycoprotein expression in multidrug-resistant human leukemia cells that overexpress the MDR1 gene
    Hulai Wei
    Laboratory Center for Medical Science, Lanzhou Medical College, Lanzhou 730000, China
    Chin Med J (Engl) 116:1644-8. 2003
    ..To investigate the effects of arsenic trioxide (As(2)O(3)) on the apoptosis and p-glycoprotein (P-gp) expression of multidrug-resistant human leukemia cells...
  3. ncbi request reprint [Arsenic trioxide inhibits P-glycoprotein expression in multidrug-resistant human leukemia K562/ADM cell line that overexpresses mdr-1 gene and enhances their chemotherapeutic sensitivity]
    Hu lai Wei
    Laboratory Center for Medical Science, Lanzhou Medical College, Lanzhou 730000, China
    Zhonghua Xue Ye Xue Za Zhi 24:28-31. 2003
    ....
  4. ncbi request reprint [The relationship between multi-drug resistance and proportion of leukemia stem cells and expression of drug transporters in drug-resistant leukemia K562/ADM cells]
    Juan Yi
    Laboratory Center for Medical Science, School of Medicine, Lanzhou University, Lanzhou, China
    Zhonghua Yi Xue Za Zhi 89:1741-4. 2009
    ..To investigate the drug resistance, proportion of leukemia stem cells (LSC) and expression of P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) in drug-sensitive and multidrug-resistant leukemia cell population...
  5. ncbi request reprint [siRNA silences mdr1 gene expression and reverses apoptosis resistance of K562/ADM cells line]
    Hu lai Wei
    Laboratory Center for Medical Science, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, Lanzhou University, Lanzhou 730000, China
    Zhonghua Xue Ye Xue Za Zhi 28:388-90. 2007
    ..To explore the effect of small interfering RNA(siRNA) on silence of mdr1 gene and reversal of apoptosis resistance in multidrug-resistant (MDR) human leukemia K562/ADM cell...
  6. ncbi request reprint Arsenic trioxide overcomes apoptosis inhibition in K562/ADM cells by regulating vital components in apoptotic pathway
    Dong Hai Wang
    Molecular Cell Biology Research Center, Key Laboratory of Preclinical Study for Drugs of Gansu Province, Lanzhou University School of Medicine, Lanzhou 730000, PR China
    Pharmacol Res 52:376-85. 2005
    ..Taken together, As(2)O(3) is able to reverse the apoptosis resistance in drug-resistant K562/ADM cells by modulating expression or activity of key factors associated with apoptosis induction...
  7. ncbi request reprint The crystal structures of copper(II), manganese(II), and nickel(II) complexes of a (Z)-2-hydroxy-N'-(2-oxoindolin-3-ylidene) benzohydrazide--potential antitumor agents
    Xia Zhong
    College of Chemistry and Chemical Engineering and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China
    Bioorg Med Chem Lett 17:3774-7. 2007
    ..The complexes have been structurally characterized by X-ray crystallography. Among the three complexes, the Cu(II) complex had the novel highest antitumor activity...