Bing Su

Summary

Affiliation: Kunming Institute of Zoology
Country: China

Publications

  1. pmc Functional divergence of the rapidly evolving miR-513 subfamily in primates
    Zhenghua Sun
    Yunnan Key Laboratory of Primate Biomedical Research, Kunming 650217, China
    BMC Evol Biol 13:255. 2013
  2. doi Peak identification for ChIP-seq data with no controls
    Yan Feng Zhang
    Chinese Academy of Sciences, Kunming, China
    Dongwuxue Yanjiu 33:E121-8. 2012
  3. doi [Research proceedings on primate comparative genomics]
    Cheng Hong Liao
    College of Agriculture, Hainan University, Haikou, China
    Dongwuxue Yanjiu 33:108-18. 2012
  4. pmc CpG island density and its correlations with genomic features in mammalian genomes
    Leng Han
    Department of Psychiatry, Virginia Commonwealth University, Richmond, VA 23298, USA
    Genome Biol 9:R79. 2008
  5. pmc Rapid evolution of mammalian X-linked testis microRNAs
    Xuejiang Guo
    Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing 210029, PR China
    BMC Genomics 10:97. 2009
  6. pmc Paternal genetic affinity between Western Austronesians and Daic populations
    Hui Li
    MOE Key Laboratory of Contemporary Anthropology and Center for Evolutionary Biology, School of Life Sciences and Institutes for Biomedical Sciences, Fudan University, Shanghai 200433, China
    BMC Evol Biol 8:146. 2008
  7. doi Association of RELN promoter SNPs with schizophrenia in the Chinese population
    Lü Hua Chang
    The First Affiliated Hospital of Kunming Medical College, Kunming 650032, China
    Dongwuxue Yanjiu 32:504-8. 2011
  8. doi [Association of RELN SNP rs7341475 with schizophrenia in the Chinese population]
    Xing yan Liu
    The Second People s Hospital of Yuxi City, Yuxi 653101, China
    Dongwuxue Yanjiu 32:499-503. 2011
  9. pmc Y-chromosome evidence of southern origin of the East Asian-specific haplogroup O3-M122
    Hong Shi
    Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Kunming, China
    Am J Hum Genet 77:408-19. 2005
  10. doi Identification of a Tibetan-specific mutation in the hypoxic gene EGLN1 and its contribution to high-altitude adaptation
    Kun Xiang
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    Mol Biol Evol 30:1889-98. 2013

Collaborators

Detail Information

Publications73

  1. pmc Functional divergence of the rapidly evolving miR-513 subfamily in primates
    Zhenghua Sun
    Yunnan Key Laboratory of Primate Biomedical Research, Kunming 650217, China
    BMC Evol Biol 13:255. 2013
    ..Evidence suggests that this subfamily is preferentially expressed in the testis, but otherwise, to date, the evolutionary history and functional significance of this miRNA subfamily has remained largely unexplored...
  2. doi Peak identification for ChIP-seq data with no controls
    Yan Feng Zhang
    Chinese Academy of Sciences, Kunming, China
    Dongwuxue Yanjiu 33:E121-8. 2012
    ..Additionally, using in silico data, only a small number of peaks were identified, suggesting the significantly low FDR for PCWC...
  3. doi [Research proceedings on primate comparative genomics]
    Cheng Hong Liao
    College of Agriculture, Hainan University, Haikou, China
    Dongwuxue Yanjiu 33:108-18. 2012
    ....
  4. pmc CpG island density and its correlations with genomic features in mammalian genomes
    Leng Han
    Department of Psychiatry, Virginia Commonwealth University, Richmond, VA 23298, USA
    Genome Biol 9:R79. 2008
    ..To date, there seems to be no comparative analysis of CpG islands and their density at the DNA sequence level among mammalian genomes and of their correlations with other genome features...
  5. pmc Rapid evolution of mammalian X-linked testis microRNAs
    Xuejiang Guo
    Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing 210029, PR China
    BMC Genomics 10:97. 2009
    ..Previous studies have focused on highly conserved miRNAs, but nonconserved miRNAs represent a potentially important source of novel functionalities during evolution...
  6. pmc Paternal genetic affinity between Western Austronesians and Daic populations
    Hui Li
    MOE Key Laboratory of Contemporary Anthropology and Center for Evolutionary Biology, School of Life Sciences and Institutes for Biomedical Sciences, Fudan University, Shanghai 200433, China
    BMC Evol Biol 8:146. 2008
    ....
  7. doi Association of RELN promoter SNPs with schizophrenia in the Chinese population
    Lü Hua Chang
    The First Affiliated Hospital of Kunming Medical College, Kunming 650032, China
    Dongwuxue Yanjiu 32:504-8. 2011
    ..Collectively, our results suggested variants in the RELN promoter may not harbor risk SNPs associated with schizophrenia in the Chinese population...
  8. doi [Association of RELN SNP rs7341475 with schizophrenia in the Chinese population]
    Xing yan Liu
    The Second People s Hospital of Yuxi City, Yuxi 653101, China
    Dongwuxue Yanjiu 32:499-503. 2011
    ..The results do not indicate any association of rs7341475 with schizophrenia, which suggests it is not a risk SNP for schizophrenia in Han Chinese...
  9. pmc Y-chromosome evidence of southern origin of the East Asian-specific haplogroup O3-M122
    Hong Shi
    Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Kunming, China
    Am J Hum Genet 77:408-19. 2005
    ..It was estimated that the early northward migration of the O3-M122 lineages in East Asia occurred approximately 25,000-30,000 years ago, consistent with the fossil records of modern humans in East Asia...
  10. doi Identification of a Tibetan-specific mutation in the hypoxic gene EGLN1 and its contribution to high-altitude adaptation
    Kun Xiang
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    Mol Biol Evol 30:1889-98. 2013
    ....
  11. doi Genetic evidence of paleolithic colonization and neolithic expansion of modern humans on the tibetan plateau
    Xuebin Qi
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    Mol Biol Evol 30:1761-78. 2013
    ....
  12. doi Allelic differences between Han Chinese and Europeans for functional variants in ZNF804A and their association with schizophrenia
    Ming Li
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, China
    Am J Psychiatry 168:1318-25. 2011
    ..The authors conducted both association and functional analyses to test whether ZNF804A is a risk gene for schizophrenia in Chinese populations...
  13. pmc Functional divergence of the brain-size regulating gene MCPH1 during primate evolution and the origin of humans
    Lei Shi
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, 32 East Jiao Chang Road, Kunming, Yunnan 650223, PR China
    BMC Biol 11:62. 2013
    ..During this evolution, the divergence of MCPH1 protein sequences among primates may have caused functional changes that contribute to brain enlargement...
  14. pmc Rapid evolution and copy number variation of primate RHOXF2, an X-linked homeobox gene involved in male reproduction and possibly brain function
    Ao Lei Niu
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology and Kunming Primate Research Center, Chinese Academy of Sciences, Kunming, Yunnan 650223, China
    BMC Evol Biol 11:298. 2011
    ..As male reproductive system is often the target of natural and/or sexual selection during evolution, in this study, we aim to dissect the pattern of molecular evolution of RHOXF2 in primates and its potential functional consequence...
  15. pmc The ADH1B Arg47His polymorphism in east Asian populations and expansion of rice domestication in history
    Yi Peng
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology and Kunming Primate Research Centre, Chinese Academy of Sciences, Kunming, China
    BMC Evol Biol 10:15. 2010
    ....
  16. doi A novel fusion gene, TRIM5-Cyclophilin A in the pig-tailed macaque determines its susceptibility to HIV-1 infection
    Cheng Hong Liao
    Kunming Primate Research Center, Chinese Academy of Sciences, Kunming, Yunnan, China
    AIDS 21:S19-26. 2007
    ..However, the pig-tailed macaque (Macaca nemestrina) is an exception and is susceptible to HIV-1 infection. This study dissects the molecular mechanism of the pig-tailed macaque's susceptibility to HIV-1 infection...
  17. ncbi Detecting lineage-specific adaptive evolution of brain-expressed genes in human using rhesus macaque as outgroup
    Xiao Jing Yu
    Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China
    Genomics 88:745-51. 2006
    ..We also demonstrated that rhesus macaque performed much better than mouse as an outgroup in identifying lineage-specific selection in humans...
  18. ncbi Molecular evolution of CXCR1, a G protein-coupled receptor involved in signal transduction of neutrophils
    Ying Liu
    Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
    J Mol Evol 61:691-6. 2005
    ..The sliding window analysis and the codon-based neutrality test identified signatures of positive selection at the N-terminal ligand/receptor recognition domain of human CXCR1...
  19. doi Global distribution of Y-chromosome haplogroup C reveals the prehistoric migration routes of African exodus and early settlement in East Asia
    Hua Zhong
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology and Kunming Primate Research Centre, Chinese Academy of Sciences, Kunming, PR China
    J Hum Genet 55:428-35. 2010
    ..The northward expansion of Hg C in East Asia started approximately 40 thousand of years ago (KYA) along the coastline of mainland China and reached Siberia approximately 15 KYA and finally made its way to the Americas...
  20. pmc Y chromosome evidence of earliest modern human settlement in East Asia and multiple origins of Tibetan and Japanese populations
    Hong Shi
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology and Kunming Primate Research Centre, Chinese Academy of Sciences, Kunming, PR China
    BMC Biol 6:45. 2008
    ..However, the fragmented distribution of one East Asian specific Y chromosome lineage (D-M174), which is found at high frequencies only in Tibet, Japan and the Andaman Islands, is inconsistent with this scenario...
  21. doi Analysis of common genetic variants identifies RELN as a risk gene for schizophrenia in Chinese population
    Ming Li
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    World J Biol Psychiatry 14:91-9. 2013
    ..Conclusions: Our findings demonstrate that RELN is a susceptibility gene for schizophrenia in Chinese population, and it is likely a common risk gene for schizophrenia in major populations worldwide...
  22. pmc Winter temperature and UV are tightly linked to genetic changes in the p53 tumor suppressor pathway in Eastern Asia
    Hong Shi
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology and Kunming Primate Research Centre, Chinese Academy of Sciences, Kunming 650223, PR China
    Am J Hum Genet 84:534-41. 2009
    ..Haplotype-based selection analysis further suggests that this is a striking example of two functional polymorphisms being strongly selected for in human populations in response to environmental stresses...
  23. ncbi Functional consequences of new exon acquisition in mammalian chromodomain Y-like (CDYL) genes
    Xin Li
    CAS Max Planck Junior Research Group, Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences CAS, Kunming, Yunnan 650223, China
    Trends Genet 23:427-31. 2007
    ....
  24. ncbi Adaptive evolution of MRGX2, a human sensory neuron specific gene involved in nociception
    Su Yang
    Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
    Gene 352:30-5. 2005
    ..Such critical substitutions may alter the interactions between MRGX2 protein and its ligand, thus, potentially led to adaptive changes of the pain-perception-related nervous system during human evolution...
  25. doi ZNF804A and schizophrenia susceptibility in Asian populations
    Ming Li
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    Am J Med Genet B Neuropsychiatr Genet 159:794-802. 2012
    ....
  26. doi Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility
    Ming Li
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    Schizophr Res 142:200-5. 2012
    ..Gene expression analyses indicated an up-regulation of VRK2 in schizophrenia patients. Our data provide further evidence for the contribution of VRK2 to schizophrenia...
  27. pmc Replicated associations of TNFAIP3, TNIP1 and ETS1 with systemic lupus erythematosus in a southwestern Chinese population
    Hua Zhong
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China
    Arthritis Res Ther 13:R186. 2011
    ..To better understand the genetic risk factors of SLE, we investigated the associations of seven SLE susceptibility genes in a Chinese population, including FCGR3A, FCGR2A, TNFAIP3, TLR9, TREX1, ETS1 and TNIP1...
  28. ncbi Rapid evolution, genetic variations, and functional association of the human spermatogenesis-related gene NYD-SP12
    Qu Zhang
    Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
    J Mol Evol 65:154-61. 2007
    ..In the association analysis, we demonstrated significant frequency discrepancy of a synonymous sequence polymorphism among the clinical groups with different sperm traits...
  29. doi Identification and functional characterization of a primate-specific E2F1 binding motif regulating MCPH1 expression
    Lei Shi
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, China
    FEBS J 279:491-503. 2012
    ..Nucleotide sequence data are available in the GenBank database (http://www.ncbi.nlm.nih.gov/genbank/) under accession numbers JN573214, JN573215 and JN573216...
  30. doi Functional characterization of the human-specific (type II) form of kallikrein 8, a gene involved in learning and memory
    Zhi Xiang Lu
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
    Cell Res 19:259-67. 2009
    ....
  31. ncbi A human-specific mutation leads to the origin of a novel splice form of neuropsin (KLK8), a gene involved in learning and memory
    Zhi Xiang Lu
    Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    Hum Mutat 28:978-84. 2007
    ..Our results demonstrate a molecular mechanism for the creation of novel proteins through alternative splicing in the central nervous system during human evolution...
  32. pmc Rapid evolution of an X-linked microRNA cluster in primates
    Rui Zhang
    Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
    Genome Res 17:612-7. 2007
    ..We propose that, like protein-coding genes, miRNA genes involved in male reproduction are subject to rapid adaptive changes that may contribute to functional novelties during evolution...
  33. pmc Accelerated evolution of the pituitary adenylate cyclase-activating polypeptide precursor gene during human origin
    Yin Qiu Wang
    Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Yunnan
    Genetics 170:801-6. 2005
    ..Our data suggested that the PACAP precursor gene underwent adaptive changes during human origin and may have contributed to the formation of human cognition...
  34. ncbi No accelerated evolution of 3'UTR region in human for brain-expressed genes
    Yi Li
    Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
    Gene 383:38-42. 2006
    ..The 3'UTRs of the brain-expressed genes in primates has a similar evolutionary rate with the synonymous sites of the gene coding region, indicating a neutral evolution of the 3'UTR sequences in human...
  35. ncbi Recent origin of a hominoid-specific splice form of neuropsin, a gene involved in learning and memory
    Yi Li
    Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming, Yunnan, China
    Mol Biol Evol 21:2111-5. 2004
    ....
  36. pmc Genetic evidence of an East Asian origin and paleolithic northward migration of Y-chromosome haplogroup N
    Hong Shi
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    PLoS ONE 8:e66102. 2013
    ..0-10.0 kya. This northward migration of Hg N likewise coincides with retreating ice sheets after the Last Glacial Maximum (22-18 kya) in mainland East Asia. ..
  37. pmc MicroRNA profiling of rhesus macaque embryonic stem cells
    Zhenghua Sun
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
    BMC Genomics 12:276. 2011
    ..However, studies on rhesus macaque (r)ESCs are lacking due to limited rESC availability and a need for systematic analyses of fundamental rESC characteristics...
  38. pmc Meta-analysis indicates that the European GWAS-identified risk SNP rs1344706 within ZNF804A is not associated with schizophrenia in Han Chinese population
    Ming Li
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, People s Republic of China
    PLoS ONE 8:e65780. 2013
    ....
  39. doi Extended Y chromosome investigation suggests postglacial migrations of modern humans into East Asia via the northern route
    Hua Zhong
    Center for Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
    Mol Biol Evol 28:717-27. 2011
    ....
  40. doi Molecular evolution of a primate-specific microRNA family
    Rui Zhang
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    Mol Biol Evol 25:1493-502. 2008
    ..Finally, we observed preferential expression of miRNAs in human placenta and fetal brain, suggesting a functional importance of this family for primate development...
  41. ncbi Adaptive evolution of primate TRIM5alpha, a gene restricting HIV-1 infection
    Hong Liang Liu
    Kunming Primate Research Center, Chinese Academy of Sciences, Kunming, Yunnan, China
    Gene 362:109-16. 2005
    ....
  42. doi A common SNP of MCPH1 is associated with cranial volume variation in Chinese population
    Jin kai Wang
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, PR China
    Hum Mol Genet 17:1329-35. 2008
    ..No recent selection signal can be detected on this SNP, suggesting that the brain volume variation in human populations is likely neutral or under very weak selection in recent human history...
  43. doi MCPH1/BRIT1 represses transcription of the human telomerase reverse transcriptase gene
    Lei Shi
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, PR China
    Gene 495:1-9. 2012
    ....
  44. pmc Derivation of rhesus monkey parthenogenetic embryonic stem cells and its microRNA signature
    Qiang Wei
    Department of Reproduction and Development, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    PLoS ONE 6:e25052. 2011
    ....
  45. ncbi The testis-specific apoptosis related gene TTL.6 underwent adaptive evolution in the lineage leading to humans
    Xiao Hua Chen
    Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, the Chinese Academy of Sciences CAS, Kunming, China
    Gene 370:58-63. 2006
    ..Further analysis on sequence variations in human populations demonstrated an excess of derived common alleles, which was likely caused by genetic hitchhiking, an implication of recent positive selection on TTL.6 in human populations...
  46. doi Diversity and evolution of MicroRNA gene clusters
    Yanfeng Zhang
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650223, China
    Sci China C Life Sci 52:261-6. 2009
    ....
  47. pmc Genome sequence and global sequence variation map with 5.5 million SNPs in Chinese rhesus macaque
    Xiaodong Fang
    Beijing Genomics Institute Shenzhen, Chinese Academy of Sciences, Shenzhen 518083, China
    Genome Biol 12:R63. 2011
    ..Rhesus macaque (Macaca mulatta) is the most widely used nonhuman primate animal in biomedical research. A global map of genetic variations in rhesus macaque is valuable for both evolutionary and functional studies...
  48. pmc Adaptive evolution of SCML1 in primates, a gene involved in male reproduction
    Hai hui Wu
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, PR China
    BMC Evol Biol 8:192. 2008
    ..To test whether SCML1 is the target of selection in primates, we sequenced and compared the coding region of SCML1 in major primate lineages, and we observed the signature of positive selection in primates...
  49. ncbi Origination and evolution of a human-specific transmembrane protein gene, c1orf37-dup
    Haijing Yu
    Kunming Institute of Zoology, No 32 E Jiao Chang Road, Kunming, Yunnan 650223, P R China
    Hum Mol Genet 15:1870-5. 2006
    ..It is suggested that c1orf37-dup encodes a novel transmembrane protein in humans which potentially endows new properties to cell surface interactions...
  50. doi Genetic variations in Tibetan populations and high-altitude adaptation at the Himalayas
    Yi Peng
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology and Kunming Primate Research Center, Chinese Academy of Sciences, Kunming, China
    Mol Biol Evol 28:1075-81. 2011
    ....
  51. doi Analysis of mitochondrial genome diversity identifies new and ancient maternal lineages in Cambodian aborigines
    Xiaoming Zhang
    1 State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China 2 University of Chinese Academy of Sciences, Beijing 100101, China 3
    Nat Commun 4:2599. 2013
    ....
  52. pmc Genome-wide DNA methylation analyses in the brain reveal four differentially methylated regions between humans and non-human primates
    Jinkai Wang
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, People s Republic of China
    BMC Evol Biol 12:144. 2012
    ..Recently, several large-scale studies reported the evolutionary roles of DNA methylation; however, the role of DNA methylation on brain evolution is largely unknown...
  53. pmc The interleukin 3 gene (IL3) contributes to human brain volume variation by regulating proliferation and survival of neural progenitors
    Xiong Jian Luo
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
    PLoS ONE 7:e50375. 2012
    ..Our results demonstrate that genetic variation in the IL3 promoter regulates human brain volume and reveals novel roles of IL3 in regulating brain development...
  54. pmc MicroRNA regulation and the variability of human cortical gene expression
    Rui Zhang
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Kunming 650223, China
    Nucleic Acids Res 36:4621-8. 2008
    ..We propose that miRNAs are one of the driving forces causing expression variability in the human genome...
  55. ncbi Molecular evolution of microcephalin, a gene determining human brain size
    Yin Qiu Wang
    Key Laboratory of Cellulr and Molecular Evolutioin, Kunming Institute of Zoology, the Chinese Academy of Sciences CAS, Kunming, China
    Hum Mol Genet 13:1131-7. 2004
    ..The codon-based neutrality test also indicated the signal of positive selection on five individual amino acid sites of microcephalin, which may contribute to brain enlargement during primate evolution and human origin...
  56. doi [Association of the schizophrenia susceptible gene DKK4 with brain volume in Chinese populations]
    Li Hua Zhang
    Department of Geratology, The First Affiliated Hospital of Kunming Medical College, Kunming 650031, China
    Dongwuxue Yanjiu 32:62-5. 2011
    ..Our findings support the neurodevelopmental hypothesis of the etiology of schizophrenia...
  57. doi Small but influential: the role of microRNAs on gene regulatory network and 3'UTR evolution
    Rui Zhang
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology and Kunming Primate Research Center, Chinese Academy of Sciences, Kunming 650223, China
    J Genet Genomics 36:1-6. 2009
    ....
  58. doi Human-Specific Hypomethylation of CENPJ, a Key Brain Size Regulator
    Lei Shi
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    Mol Biol Evol 31:594-604. 2014
    ....
  59. doi Genetic association and identification of a functional SNP at GSK3β for schizophrenia susceptibility
    Ming Li
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
    Schizophr Res 133:165-71. 2011
    ..In this study, we test whether the genetic variants in GSK3β contribute to the risk of schizophrenia in Chinese population...
  60. pmc An evaluation of association between a novel hippocampal biology related SNP (rs7294919) and schizophrenia
    Jiewei Liu
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China University of Chinese Academy of Sciences, Beijing, China
    PLoS ONE 8:e80696. 2013
    ....
  61. pmc Multiple inter-kingdom horizontal gene transfers in the evolution of the phosphoenolpyruvate carboxylase gene family
    Yingmei Peng
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, PR China
    PLoS ONE 7:e51159. 2012
    ..These results imply that inter-kingdom HGTs played important roles in the evolution of the pepcase gene family and furthermore that HGTsare a more frequent evolutionary event than previouslythought...
  62. pmc Characterization and comparison of the tissue-related modules in human and mouse
    Ruolin Yang
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    PLoS ONE 5:e11730. 2010
    ..Hence, the comparative analysis between species at the module level would shed more light on the mechanisms underlying the evolution of organisms than the traditional comparative genomics approaches...
  63. ncbi Construction, characterization and chromosomal mapping of bacterial artificial chromosome (BAC) library of Yunnan snub-nosed monkey (Rhinopithecus bieti)
    Huai Liang XU
    Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming, China
    Chromosome Res 12:251-62. 2004
    ..The DNA sequence data reported in this paper were deposited in GenBank and assigned the accession number CG891489-CG891703...
  64. pmc Molecular adaptation of modern human populations
    Hong Shi
    State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology and Kunming Primate Research Centre, Chinese Academy of Sciences, Kunming 650223, China
    Int J Evol Biol 2011:484769. 2011
    ....
  65. pmc The dual origin and Siberian affinities of Native American Y chromosomes
    Jeffrey T Lell
    Center for Molecular Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Am J Hum Genet 70:192-206. 2002
    ..This migration event contributed to the modern genetic pool of the Na-Dene and Amerinds of North and Central America...
  66. pmc Genetic studies of human diversity in East Asia
    Feng Zhang
    Institute of Genetics, School of Life Sciences, Fudan University, Shanghai 200433, People s Republic of China
    Philos Trans R Soc Lond B Biol Sci 362:987-95. 2007
    ..e. Central Asia, the Sub-continent, America and the Pacific Islands), the origin of Sino-Tibetan populations and expansion of the Chinese...
  67. pmc Analyses of genetic structure of Tibeto-Burman populations reveals sex-biased admixture in southern Tibeto-Burmans
    Bo Wen
    State Key Laboratory of Genetic Engineering and Center for Anthropological Studies, Fudan University, Shanghai, China
    Am J Hum Genet 74:856-65. 2004
    ..This is the first genetic evidence revealing sex-biased admixture in STB populations, which has genetic, historical, and anthropological implications...
  68. ncbi Genetic evidence supports demic diffusion of Han culture
    Bo Wen
    State Key Laboratory of Genetic Engineering and Center for Anthropological Studies, School of Life Sciences and Morgan Tan International Center for Life Sciences, Fudan University, Shanghai 200433, China
    Nature 431:302-5. 2004
    ..16 billion (2000 census), and are by far the largest ethnic group in the world. The expansion process of Han culture is thus of great interest to researchers in many fields...
  69. ncbi Genetic structure of Hmong-Mien speaking populations in East Asia as revealed by mtDNA lineages
    Bo Wen
    State Key Laboratory of Genetic Engineering and Center for Anthropological Studies, School of Life Sciences, Fudan University, Shanghai, China
    Mol Biol Evol 22:725-34. 2005
    ..Moreover, our data defined some new (sub-)haplogroups (A6, B4e, B4f, C5, F1a1, F1a1a, and R9c), which will direct further efforts to improve the phylogeny of East Asian mtDNAs...
  70. ncbi [Gene duplications specific to the amphioxus lineage]
    Wei Wang
    College of Life Science, Xiamen University, Xiamen, 361005, China
    Yi Chuan 27:143-9. 2005
    ....
  71. ncbi Features and trend of loss of promoter-associated CpG islands in the human and mouse genomes
    Cizhong Jiang
    Department of Psychiatry and Center for the Study of Biological Complexity, Virginia Commonwealth, USA
    Mol Biol Evol 24:1991-2000. 2007
    ..Our study provides a detailed view of the evolution of promoter-associated CGIs in the human and mouse genomes and our findings are helpful for understanding the evolution of mammalian genomes and the role of CGIs in gene function...
  72. ncbi Mitochondrial DNA hypervariable region-1 sequence variation and phylogeny of the concolor gibbons, Nomascus
    Keri Monda
    Ecology, Behavior and Evolution Section, Division of Biological Sciences, University of California, San Diego, La Jolla, California 92093 0116, USA
    Am J Primatol 69:1285-306. 2007
    ..There is an urgent need to obtain DNA from gibbons of known geographic provenance before they are extirpated to facilitate the conservation genetic management of the surviving animals...
  73. ncbi Comparison of Pax1/9 locus reveals 500-Myr-old syntenic block and evolutionary conserved noncoding regions
    Wei Wang
    Key Laboratory of the Ministry of Education for Cell Biology and Tumor Cell Engineering, School of Life Sciences, Xiamen University, Xiamen, China
    Mol Biol Evol 24:784-91. 2007
    ..These noncoding sequences have high possibility of being elements that regulate neighboring genes. They are likely to be a factor in the maintenance of conserved synteny over long phylogenetic distance in different deuterostome lineages...