Qi Jin

Summary

Country: China

Publications

  1. pmc The use of global transcriptional analysis to reveal the biological and cellular events involved in distinct development phases of Trichophyton rubrum conidial germination
    Tao Liu
    State Key Lab for Molecular Virology and Genetic Engineering, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, PR China
    BMC Genomics 8:100. 2007
  2. pmc Recent dermatophyte divergence revealed by comparative and phylogenetic analysis of mitochondrial genomes
    Yuan Wu
    Department of Microbiology and Immunology, Medical School of Xi an Jiaotong University, Shaanxi, 710061, PR China
    BMC Genomics 10:238. 2009
  3. pmc Global transcriptional analysis of nitrogen fixation and ammonium repression in root-associated Pseudomonas stutzeri A1501
    Yongliang Yan
    Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Key Laboratory of Crop Biotechnology, Ministry of Agriculture, Beijing 100081, China
    BMC Genomics 11:11. 2010
  4. pmc Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a
    Huan Nie
    College of Biological Sciences China Agricultural University, Beijing 100094, China
    BMC Genomics 7:173. 2006
  5. pmc Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157
    Qi Jin
    State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100052, China
    Nucleic Acids Res 30:4432-41. 2002
  6. ncbi request reprint Comparison of the virulence plasmid genomes of two strains of Shigella which lost the ability to bind Congo red
    Zhaohui Xiong
    State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100052, China
    Sci China C Life Sci 49:141-8. 2006
  7. ncbi request reprint Characterization of ST-4821 complex, a unique Neisseria meningitidis clone
    Junping Peng
    State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Beijing 100052, China
    Genomics 91:78-87. 2008
  8. pmc The use of comparative genomic hybridization to characterize genome dynamics and diversity among the serotypes of Shigella
    Junping Peng
    State Key Laboratory for Molecular Virology and Genetic Engineering, Chinese Center for Disease Control and Prevention, Beijing 100176, China
    BMC Genomics 7:218. 2006
  9. pmc Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery
    Fan Yang
    State Key Laboratory for Molecular Virology and Genetic Engineering, Chinese Ministry of Public Health, Beijing 100052, China
    Nucleic Acids Res 33:6445-58. 2005
  10. pmc VFDB 2008 release: an enhanced web-based resource for comparative pathogenomics
    Jian Yang
    State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100176, China
    Nucleic Acids Res 36:D539-42. 2008

Collaborators

Detail Information

Publications54

  1. pmc The use of global transcriptional analysis to reveal the biological and cellular events involved in distinct development phases of Trichophyton rubrum conidial germination
    Tao Liu
    State Key Lab for Molecular Virology and Genetic Engineering, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, PR China
    BMC Genomics 8:100. 2007
    ..Conidia are considered to be the primary cause of infections by Trichophyton rubrum...
  2. pmc Recent dermatophyte divergence revealed by comparative and phylogenetic analysis of mitochondrial genomes
    Yuan Wu
    Department of Microbiology and Immunology, Medical School of Xi an Jiaotong University, Shaanxi, 710061, PR China
    BMC Genomics 10:238. 2009
    ..However, only one complete dermatophyte mitochondrial genome (E. floccosum) has previously been determined...
  3. pmc Global transcriptional analysis of nitrogen fixation and ammonium repression in root-associated Pseudomonas stutzeri A1501
    Yongliang Yan
    Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Key Laboratory of Crop Biotechnology, Ministry of Agriculture, Beijing 100081, China
    BMC Genomics 11:11. 2010
    ..Although the regulatory cascades that control the transcription of the nif genes in proteobacteria have been well investigated, there are limited data on the kinetics of ammonium-dependent repression of nitrogen fixation...
  4. pmc Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a
    Huan Nie
    College of Biological Sciences China Agricultural University, Beijing 100094, China
    BMC Genomics 7:173. 2006
    ..To investigate the intra-species diversity of S. flexneri genomes further, we have sequenced the complete genome of S. flexneri 5b strain 8401 (abbreviated Sf8401) and compared it with S. flexneri 2a (Sf301)...
  5. pmc Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157
    Qi Jin
    State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100052, China
    Nucleic Acids Res 30:4432-41. 2002
    ..coli strains. All of these could be subjected to investigations towards novel preventative and treatment strategies against shigellosis...
  6. ncbi request reprint Comparison of the virulence plasmid genomes of two strains of Shigella which lost the ability to bind Congo red
    Zhaohui Xiong
    State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100052, China
    Sci China C Life Sci 49:141-8. 2006
    ..Whether these genes determine the Crb function requires continued investigation...
  7. ncbi request reprint Characterization of ST-4821 complex, a unique Neisseria meningitidis clone
    Junping Peng
    State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Beijing 100052, China
    Genomics 91:78-87. 2008
    ..Genome comparison between the newly emerged hyperinvasive isolates belonging to different serogroups will further our understanding of their respective pathogenetic mechanisms...
  8. pmc The use of comparative genomic hybridization to characterize genome dynamics and diversity among the serotypes of Shigella
    Junping Peng
    State Key Laboratory for Molecular Virology and Genetic Engineering, Chinese Center for Disease Control and Prevention, Beijing 100176, China
    BMC Genomics 7:218. 2006
    ..coli K-12 with those of 43 Shigella strains from all lineages...
  9. pmc Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery
    Fan Yang
    State Key Laboratory for Molecular Virology and Genetic Engineering, Chinese Ministry of Public Health, Beijing 100052, China
    Nucleic Acids Res 33:6445-58. 2005
    ..became highly specific human pathogens with variable epidemiological and pathological features...
  10. pmc VFDB 2008 release: an enhanced web-based resource for comparative pathogenomics
    Jian Yang
    State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100176, China
    Nucleic Acids Res 36:D539-42. 2008
    ..VFDB 2008 release offers more user-friendly tools for comparative pathogenomics and it is publicly accessible at http://www.mgc.ac.cn/VFs/...
  11. doi request reprint Distribution of surface-protein variants of hyperinvasive meningococci in China
    Li Yang
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences, Beijing, China
    J Infect 58:358-67. 2009
    ..The present study investigated the distribution of FetA and PorB variable region (VR) types among meningococci belonging to hyperinvasive lineages circulating in China...
  12. doi request reprint Transcriptional profiles of response to terbinafine in Trichophyton rubrum
    Wenliang Zhang
    State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100176, China
    Appl Microbiol Biotechnol 82:1123-30. 2009
    ..TRB affected transcription of multidrug-resistance genes and some genes encoding ribosomal proteins...
  13. doi request reprint Global transcriptional profiles of Trichophyton rubrum in response to Flucytosine
    Rong Zhao
    State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Sci China C Life Sci 52:1173-85. 2009
    ..This is the first analysis of transcriptional profiles in response to 5-FC for T. rubrum. The findings may be valuable for the identification of genes involved in mechanisms of action and mechanisms of antifungal drug resistance of 5-FC...
  14. pmc ShiBASE: an integrated database for comparative genomics of Shigella
    Jian Yang
    State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100176, China
    Nucleic Acids Res 34:D398-401. 2006
    ..In addition, ShiBASE has a newly developed online comparative visualization service, Shi-align, which enables the alignment of any query sequence with the reference genome sequences...
  15. ncbi request reprint Genomic compositions and phylogenetic analysis of Shigella boydii subgroup
    Jing Wang
    State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100176, China
    Sci China C Life Sci 49:46-52. 2006
    ..boydii and to find out important clues to pathogenesis research, vaccination and the therapeutic medicine development...
  16. doi request reprint The molecular evolutionary history of Shigella spp. and enteroinvasive Escherichia coli
    Junping Peng
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences, Beijing 100730, China
    Infect Genet Evol 9:147-52. 2009
    ..EIEC strains are regarded as precursors of 'full-blown'Shigella evolved from E. coli. By gain and loss of functions, Shigella and EIEC became successful human pathogens through convergent evolution from diverse genomic backgrounds...
  17. ncbi request reprint The complete sequence and analysis of the large virulence plasmid pSS of Shigella sonnei
    Yan Jiang
    State Key Laboratory for Molecular Virology and Genetic Engineering, 6 Rongjing Eastern Street, BDA Beijing 100176, China
    Plasmid 54:149-59. 2005
    ..The pSS plasmid is a mixture of genes with different origins and functions. The sequence suggests a remarkable history of IS-mediated recombination and acquisition of DNA across a range of bacterial species...
  18. pmc An integrated approach for finding overlooked genes in Shigella
    Junping Peng
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences Peking Union Medical College, Beijing, China
    PLoS ONE 6:e18509. 2011
    ..In order to improve genome annotation, we aimed to identify novel sRNAs and sORFs in Shigella, the principal etiologic agents of bacillary dysentery...
  19. pmc TrED: the Trichophyton rubrum Expression Database
    Jian Yang
    State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100176, China
    BMC Genomics 8:250. 2007
    ..We intend to create an integrated database TrED to facilitate the study of dermatophytes, and enhance the development of effective diagnostic and treatment strategies...
  20. ncbi request reprint Transcriptional profile induced by furazolidone treatment of Shigella flexneri
    Hua Fu
    State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 100176, China
    Appl Microbiol Biotechnol 77:657-67. 2007
    ..flexneri should be considered...
  21. pmc VFDB 2012 update: toward the genetic diversity and molecular evolution of bacterial virulence factors
    Lihong Chen
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy Medical Sciences and Peking Union Medical College, Beijing 100176, China
    Nucleic Acids Res 40:D641-5. 2012
    ..In addition, the 2012 release of VFDB provides an improved user interface...
  22. doi request reprint Transcriptional profile of the Shigella flexneri response to an alkaloid: berberine
    Hua Fu
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences, Beijing, China
    FEMS Microbiol Lett 303:169-75. 2010
    ..These results provide a comprehensive view of the changes in gene expression when S. flexneri was exposed to BC, and shed light on its complicated effects on this pathogen...
  23. ncbi request reprint Characterization of serogroup C meningococci isolated from 14 provinces of China during 1966-2005 using comparative genomic hybridization
    Junping Peng
    State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing, 100052, China
    Sci China C Life Sci 50:1-6. 2007
    ..The results will provide a valuable resource from which one can analyze the genome composition and genetic background of serogroup C meningococci in China...
  24. pmc Subpopulation analysis of heteroresistance to fluoroquinolone in Mycobacterium tuberculosis isolates from Beijing, China
    Xiaobing Zhang
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences, Beijing, China
    J Clin Microbiol 50:1471-4. 2012
    ....
  25. pmc Unbiased parallel detection of viral pathogens in clinical samples by use of a metagenomic approach
    Jian Yang
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, 6 Rongjing Eastern Street, BDA, Beijing 100176, China
    J Clin Microbiol 49:3463-9. 2011
    ....
  26. pmc Complete genome sequence of the neonatal-meningitis-associated Escherichia coli strain CE10
    Shuting Lu
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy Medical Sciences and Peking Union Medical College, Beijing 100176, China
    J Bacteriol 193:7005. 2011
    ..coli strain CE10, a unique K1 strain with a functional type III secretion system. Functional analysis of the genome should enhance our knowledge of the pathogenesis of neonatal E. coli K1 meningitis...
  27. pmc Transcriptional profiles of the response to ketoconazole and amphotericin B in Trichophyton rubrum
    Lu Yu
    State Key Laboratory for Molecular Virology and Genetic Engineering, Chinese Center for Disease Control and Prevention, Beijing 100176, China
    Antimicrob Agents Chemother 51:144-53. 2007
    ..This is the first report of the use of microarray analysis to determine the effects of drug action in T. rubrum...
  28. doi request reprint Research progress in Shigella in the postgenomic era
    Junping Peng
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100176, China
    Sci China Life Sci 53:1284-90. 2010
    ..This paper reviews contemporary understanding of genomics, transcriptomics, proteomics and the structural biology of Shigella...
  29. pmc Prevalence of drug-resistant tuberculosis in mainland China: systematic review and meta-analysis
    Yu Yang
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    PLoS ONE 6:e20343. 2011
    ..Surveillance of anti-TB drug resistance is important for monitoring TB control strategies. However, the status of drug-resistant TB in China has been reported inconsistently...
  30. pmc SLC11A1 (NRAMP1) polymorphisms and tuberculosis susceptibility: updated systematic review and meta-analysis
    Xiangwei Li
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    PLoS ONE 6:e15831. 2011
    ..The relation between SLC11A1 polymorphisms and tuberculosis susceptibility has been studied in different populations...
  31. doi request reprint Identification of small interfering RNAs which inhibit the replication of several Enterovirus 71 strains in China
    Zhiqiang Wu
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences, No 6 Rongjing East Street, Yi zhuang, Beijing 100176, China
    J Virol Methods 159:233-8. 2009
    ..These strategies and results suggest that RNAi has potential therapeutic use for the suppression of EV 71 infection in a broad spectrum of viral strains...
  32. ncbi request reprint Genotypic analysis of serogroups other than A, B or C of Neisseria meningitidis in China
    Jie Yang
    State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Centre for Disease Control and Prevention, Beijing, China
    Scand J Infect Dis 39:819-21. 2007
    ..Among these isolates, none of the well-documented ST complexes found worldwide was present...
  33. ncbi request reprint Construction, detection and microarray analysis on the Shigella flexneri 2a sitC mutant
    Moqing Liu
    State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100176, China
    Sci China C Life Sci 48:228-40. 2005
    ..Additionally, the number of these genes and their increase amplitude in MTS are more than those in Sf301. Together, these results confirmed that Sit iron-transport system is important for the growth of Shigella...
  34. ncbi request reprint [Atypical endometriosis: a clinicopathologic study of 163 cases]
    Dong Hui Guo
    Department of Pathology, Tianjin Central Obstetrics and Gynecology Hospital, Tianjin 300052, China
    Zhonghua Fu Chan Ke Za Zhi 43:831-4. 2008
    ..To investigate the clinicopathologic features of atypical endometriosis (AEM) and to discuss the relationship between AEM and tumors...
  35. ncbi request reprint Rapid identification of small interfering RNA that can effectively inhibit the replication of multiple influenza B virus strains
    Yongzhen Gao
    State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100176, China
    Antivir Ther 11:431-8. 2006
    ..6 microg ribavirin. These results indicated that RNA interference warrants further study for management of influenza B virus infections...
  36. doi request reprint Genes under positive selection in Mycobacterium tuberculosis
    Yuan Zhang
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100176, China
    Comput Biol Chem 35:319-22. 2011
    ..The functional discussion of our findings implied that those positively selected genes were highly involved in antigen variations and immune evasions of Mycobacterium tuberculosis...
  37. ncbi request reprint [Analysis of secreted proteases of Trichophyton rubrum]
    Wen Chuan Leng
    State Key Laboratory for Molecular Virology and Genetic Engineering, Chinese Center for Disease Control and Prevention, Beijing 100176, China
    Wei Sheng Wu Xue Bao 45:601-5. 2005
    ..rubrum infection. These results provide a clue to further research on the infection and pathogencity of T. rubrum...
  38. ncbi request reprint [Inhibition of HIV virus-like particles production by BST-2]
    Ying Lian Du
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
    Bing Du Xue Bao 27:319-25. 2011
    ..Consistent with a direct tethering mechanism, we confirmed that proteolysis releases restricted virions and further showed that this removed the ectodomain of BST-2 from the cell surface...
  39. pmc Evaluation of twelve real-time reverse transcriptase PCR primer-probe sets for detection of pandemic influenza A/H1N1 2009 virus
    Yaowu Yang
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology IPB, Chinese Academy of Medical Sciences and Peking Union Medical College CAMS and PUMC, Beijing 100730, China
    J Clin Microbiol 49:1434-40. 2011
    ....
  40. pmc Anal HPV infection in HIV-positive men who have sex with men from China
    Lei Gao
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    PLoS ONE 5:e15256. 2010
    ..However, HIV and anal HPV co-infection among MSM has not been addressed in China...
  41. pmc Characteristics of embB mutations in multidrug-resistant Mycobacterium tuberculosis isolates in Henan, China
    Dawei Shi
    State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100176, China
    J Antimicrob Chemother 66:2240-7. 2011
    ..To determine the association between embB mutations and drug resistance, and to further investigate the mechanism of embB mutations involved in the development of ethambutol and multidrug resistance in Mycobacterium tuberculosis...
  42. pmc VFDB: a reference database for bacterial virulence factors
    Lihong Chen
    State Key Laboratory for Molecular Virology and Genetic Engineering, Beijing 100052, China
    Nucleic Acids Res 33:D325-8. 2005
    ..Furthermore, a BLAST search tool against all known VF-related genes is also available. VFDB provides a unified gateway to store, search, retrieve and update information about VFs from various bacterial pathogens...
  43. ncbi request reprint Identification and characterization of simple sequence repeats in the genomes of Shigella species
    Jian Yang
    Laboratory of Bioinformatics, Institute of Biophysics, CAS, Datun Road 15, Chaoyang District, 100101 Beijing, China
    Gene 322:85-92. 2003
    ..Hence, SSRs may serve as genotyping markers for epidemiological investigations, and may offer insights into evolutionary adaptation of the pathogens...
  44. ncbi request reprint Therapeutic effect of CpG-enriched plasmid administration on the tight-skin mouse model of scleroderma
    Yan Shen
    Department of Immunology, Yokohama City University School of Medicine, Fukuura 3 9, Kanazawa Ku, Yokohama, Kanagawa 236 0004, Japan
    J Autoimmun 24:183-90. 2005
    ..These results suggest that repeated administration of a CpG-enriched plasmid can ameliorate scleroderma-like syndrome by biasing Th1 immunity in young Tsk/+mice...
  45. ncbi request reprint Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing
    Shuang Xi Ren
    Chinese National Human Genome Center at Shanghai, 250 Bi Bo Road, Zhang Jiang High Tech Park, Shanghai 201203, China
    Nature 422:888-93. 2003
    ....
  46. ncbi request reprint GenomeComp: a visualization tool for microbial genome comparison
    Jian Yang
    Laboratory of Bioinformatics, Institute of Biophysics, CAS, Datun Road 15, Chaoyang District, Beijing 100101, PR China
    J Microbiol Methods 54:423-6. 2003
    ..This software provides a new visualizing tool for microbe comparative genomics...
  47. ncbi request reprint Mutation screening of BMP4, BMP7, HOXA4 and HOXB6 genes in Chinese patients with hypospadias
    Taiji Chen
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, CAMS and PUMC, Beijing, China
    Eur J Hum Genet 15:23-8. 2007
    ..Further functional studies are required to make the associations clear between these variants and hypospadias...
  48. ncbi request reprint The DNA sequence, annotation and analysis of human chromosome 3
    Donna M Muzny
    Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nature 440:1194-8. 2006
    ....
  49. ncbi request reprint Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228)
    Yue Qing Zhang
    Laboratory of Medical Molecular Virology, Shanghai Medical College, Fudan University, 138 Yi Xue Yuan Road, Shanghai, 200032, China
    Mol Microbiol 49:1577-93. 2003
    ..No mec genes, IS256, IS257, were found in ATCC 12228. It is suggested that the absence of the ica operon is a genetic marker in commensal Staphylococcus epidermidis strains which are less likely to become invasive...
  50. ncbi request reprint Intranasal delivery of chitosan-DNA vaccine generates mucosal SIgA and anti-CVB3 protection
    Wei Xu
    Department of Immunology and Key Laboratory of Molecular Medicine of Ministry of Education, Shanghai Medical College, Fudan University, Shanghai 200032, PR China
    Vaccine 22:3603-12. 2004
    ..Together, Our data show that intranasal delivery of chitosan-DNA vaccine successfully induced mucosal SIgA secretion and might be a promising vaccine candidate to protect against CVB3 infection...
  51. ncbi request reprint LDA--a java-based linkage disequilibrium analyzer
    Keyue Ding
    Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, National Laboratory of Medical Molecular Biology, Beijing, 100005, People s Republic of China
    Bioinformatics 19:2147-8. 2003
    ..It is most suitable for molecular geneticists, who are focusing on LD measures estimation, statistical significance test and extent prediction...
  52. ncbi request reprint Molecular cloning, expression, and purification of SARS-CoV nsp13
    Zheng Fan
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, National Human Genome Center, Beijing 100005, China
    Protein Expr Purif 41:235-40. 2005
    ..The protein was validated by western blot and MS analysis. A large quantity of the nsp13 protein obtained with this method may be useful for further study of its structure and function...
  53. ncbi request reprint DLP, a novel Dim1 family protein implicated in pre-mRNA splicing and cell cycle progression
    Xiaojing Sun
    Department of Biochemistry and Molecular Biology, Peking University Health Science Center, 38 Xue Yuan Road, Beijing 100083, China
    J Biol Chem 279:32839-47. 2004
    ..Collectively, our experiments indicated that DLP is implicated in not only cell cycle progression but also in a more specific molecular process such as pre-mRNA splicing...
  54. ncbi request reprint [Cloning, expression and purification of SARS coronavirus PUMC2 strain nucleocapsid protein]
    Xin Yu Tan
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, CAMS and PUMC, Beijing 10005, China
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao 25:504-7. 2003
    ..To clone, express and purify nucleocapsid protein from SARS coronavirus PUMC2 strain...