- [Effect of berberine on the differentiation and apoptosis of K562 cell line]Lin Jin
Biomedicine Research and Development Center, Jinan University, Guangzhou 510632, China
Zhong Yao Cai 32:384-8. 2009..To study the effect of Berberine on proliferation, differentiation and apoptosis of K562 cells for supplying the theoretical evidence on the clinical application of Coptis chinensis to cure chronic myeloid leukemia...
- [Influence of nm23-H1 gene silence in K562 cell on its differentiation toward megakaryocyte]Lin Jin
Biomedicine Research and Development Center, Institute of Pharmaceutical Science, Jinan University, Guangzhou 510632, China
Zhonghua Xue Ye Xue Za Zhi 29:384-7. 2008..To construct a stable nm23-H1-knock-down cell model with K562 cell line and study its differentiation toward megakaryocyte...
- Transcriptomic and proteomic approach to studying SNX-2112-induced K562 cells apoptosis and anti-leukemia activity in K562-NOD/SCID miceLin Jin
Guangzhoujinan Biomedicine Research and Development Center, National Engineering Research Center of Genetic Medicine, Jinan University, Guangzhou, China
FEBS Lett 583:1859-66. 2009..Additionally, SNX-2112 prolonged the survival time of NOD/SCID mice inoculated with K562 tumor cells. Our results demonstrated the therapeutic potential of SNX-2112 against human CML...