Jian Lu

Summary

Affiliation: Jiangsu University
Country: China

Publications

  1. doi request reprint 2D-DIGE and MALDI TOF/TOF MS analysis reveal that small GTPase signaling pathways may play an important role in cadmium-induced colon cell malignant transformation
    Jian Lu
    School of Medicine, Jiangsu University, Zhenjiang 212013, China Institute of Life Sciences, Jiangsu University, Zhenjiang 212013, China Electronic address
    Toxicol Appl Pharmacol 288:106-13. 2015
  2. doi request reprint Comparative proteomics analysis of midgut samples from Takifugu rubripes exposed to excessive fluoride: initial molecular response to fluorosis
    Jian Lu
    Institute of Life Sciences, Jiangsu University, Zhenjiang, P R China
    Toxicol Mech Methods 21:444-52. 2011
  3. doi request reprint Protein profiling analysis of skeletal muscle of a pufferfish, Takifugu rubripes
    Jian Lu
    Institute of Life Sciences, Jiangsu University, 301 Xuefu Road, 212013 Zhenjiang, People s Republic of China
    Mol Biol Rep 37:2141-7. 2010
  4. doi request reprint Comparative proteomics analysis of cardiac muscle samples from pufferfish Takifugu rubripes exposed to excessive fluoride: initial molecular response to fluorosis
    Jian Lu
    Institute of Life Sciences, Jiangsu University, Zhenjiang, 212013, PR China
    Toxicol Mech Methods 19:468-75. 2009
  5. doi request reprint Proteomics analysis of liver samples from puffer fish Takifugu rubripes exposed to excessive fluoride: an insight into molecular response to fluorosis
    Jian Lu
    Institute of Life Sciences, Jiangsu University, Zhenjiang 212013, People s Republic of China
    J Biochem Mol Toxicol 24:21-8. 2010
  6. doi request reprint Comparative proteomics of kidney samples from puffer fish Takifugu rubripes exposed to excessive fluoride: an insight into molecular response to fluorosis
    Jian Lu
    Institute of Life Sciences, Jiangsu University, No 301 Xuefu Road, Zhenjiang City, PR China
    Toxicol Mech Methods 20:345-54. 2010
  7. doi request reprint QM/MM-PB/SA scoring of the interaction strength between Akt kinase and apigenin analogues
    Jian Lu
    School of Medicine, Jiangsu University, Zhenjiang 212013, China Institute of Life Sciences, Jiangsu University, Zhenjiang 212013, China Electronic address
    Comput Biol Chem 52:25-33. 2014
  8. doi request reprint Characterization of ATPase activity of class II chaperonin from the hyperthermophilic archaeon Pyrococcus furiosus
    Hua You Chen
    Institute for Biological Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China
    Biotechnol Lett 31:1753-8. 2009
  9. doi request reprint Subtype distribution of Hepatitis C virus in Jiangsu, China
    Yinle Qi
    Institute of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, China
    J Med Virol 88:498-505. 2016
  10. pmc Adaptive evolution of the vertebrate skeletal muscle sodium channel
    Jian Lu
    Institute of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, PR China
    Genet Mol Biol 34:323-8. 2011

Collaborators

  • Jun Li
  • Hua You Chen
  • Yinle Qi
  • Qianqian Chen
  • Chiyu Zhang
  • Weiming Hao
  • HongXiong Guo
  • Lingxiang Mao
  • Hong Du
  • Renfei Lu
  • Fangyuan Hao
  • Zhenzhou Wan
  • Xiaoxiang Chen
  • Ke Lan
  • Lujuan Fan
  • Sichao Zhang

Detail Information

Publications11

  1. doi request reprint 2D-DIGE and MALDI TOF/TOF MS analysis reveal that small GTPase signaling pathways may play an important role in cadmium-induced colon cell malignant transformation
    Jian Lu
    School of Medicine, Jiangsu University, Zhenjiang 212013, China Institute of Life Sciences, Jiangsu University, Zhenjiang 212013, China Electronic address
    Toxicol Appl Pharmacol 288:106-13. 2015
    ..Collectively, our results suggest that activation of small GTPases contributes to cadmium-induced transformation of colon cells. ..
  2. doi request reprint Comparative proteomics analysis of midgut samples from Takifugu rubripes exposed to excessive fluoride: initial molecular response to fluorosis
    Jian Lu
    Institute of Life Sciences, Jiangsu University, Zhenjiang, P R China
    Toxicol Mech Methods 21:444-52. 2011
    ..Our results provide initial insights into the effects of excessive fluoride exposure on physiological and biochemical functions of Fugu midgut as well as on the toxicological mechanism of fluoride in both fish and human...
  3. doi request reprint Protein profiling analysis of skeletal muscle of a pufferfish, Takifugu rubripes
    Jian Lu
    Institute of Life Sciences, Jiangsu University, 301 Xuefu Road, 212013 Zhenjiang, People s Republic of China
    Mol Biol Rep 37:2141-7. 2010
    ..It is also favorable for further investigation on screening marker proteins for monitoring and controlling the quality of fish meat...
  4. doi request reprint Comparative proteomics analysis of cardiac muscle samples from pufferfish Takifugu rubripes exposed to excessive fluoride: initial molecular response to fluorosis
    Jian Lu
    Institute of Life Sciences, Jiangsu University, Zhenjiang, 212013, PR China
    Toxicol Mech Methods 19:468-75. 2009
    ..These results will contribute to our understanding for the effects of fluoride exposure on the physiological and biochemical functions of takifugu, and the toxicological mechanism of fluoride causing fluorosis in both fish and human...
  5. doi request reprint Proteomics analysis of liver samples from puffer fish Takifugu rubripes exposed to excessive fluoride: an insight into molecular response to fluorosis
    Jian Lu
    Institute of Life Sciences, Jiangsu University, Zhenjiang 212013, People s Republic of China
    J Biochem Mol Toxicol 24:21-8. 2010
    ....
  6. doi request reprint Comparative proteomics of kidney samples from puffer fish Takifugu rubripes exposed to excessive fluoride: an insight into molecular response to fluorosis
    Jian Lu
    Institute of Life Sciences, Jiangsu University, No 301 Xuefu Road, Zhenjiang City, PR China
    Toxicol Mech Methods 20:345-54. 2010
    ....
  7. doi request reprint QM/MM-PB/SA scoring of the interaction strength between Akt kinase and apigenin analogues
    Jian Lu
    School of Medicine, Jiangsu University, Zhenjiang 212013, China Institute of Life Sciences, Jiangsu University, Zhenjiang 212013, China Electronic address
    Comput Biol Chem 52:25-33. 2014
    ..A further kinase assay was conducted to determine the inhibitory activity of the four promising candidates against Akt kinase, resulting in IC50 values of 38.4, 67.5, 157.1 and 25.5 nM, respectively...
  8. doi request reprint Characterization of ATPase activity of class II chaperonin from the hyperthermophilic archaeon Pyrococcus furiosus
    Hua You Chen
    Institute for Biological Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China
    Biotechnol Lett 31:1753-8. 2009
    ..5. PfCPN had almost no ADPase activity. ADP strongly competitively inhibited PfCPN ATPase activity. Inhibition of PfCPN ATPase decreased its chaperonin activity in protecting lysozyme from heat-induced inactivation...
  9. doi request reprint Subtype distribution of Hepatitis C virus in Jiangsu, China
    Yinle Qi
    Institute of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, China
    J Med Virol 88:498-505. 2016
    ..J. Med. Virol. 88:498-505, 2016. © 2015 Wiley Periodicals, Inc. ..
  10. pmc Adaptive evolution of the vertebrate skeletal muscle sodium channel
    Jian Lu
    Institute of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, PR China
    Genet Mol Biol 34:323-8. 2011
    ..4 channel sensitivity to TTX. Most of these sites were located in the intracellular regions of the Na(v)1.4 channel, thereby implying the possible association of these regions with the regulation of voltage-sensor movement...
  11. pmc Modified Proofreading PCR for Detection of Point Mutations, Insertions and Deletions Using a ddNTP-Blocked Primer
    Weiming Hao
    Institute of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, China Pathogen Diagnostic Center, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China
    PLoS ONE 10:e0123468. 2015
    ..These results suggest that the modified PR-PCR technique is effective in detection of various mutations or polymorphisms as a simple, sensitive and promising approach. ..