Research Topics
Species | Yong Chang ChenSummaryAffiliation: Jiangsu University Country: China Publications
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Detail Information
Publications
H pylori stimulates proliferation of gastric cancer cells through activating mitogen-activated protein kinase cascadeYong Chang Chen
School of Medicine, Jiangsu University, Zhenjiang 212001, Jiangsu Province, China
World J Gastroenterol 12:5972-7. 2006..To explore the mechanism by which H pylori causes activation of gastric epithelial cells...- Analysis on the mechanism of Helicobacter pylori-induced apoptosis in gastric cancer cell line BGC-823Yongchang Chen
Department of Physiology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu Province 212001, PR China
Int J Mol Med 16:741-5. 2005..The results suggested that Hp extract initiated apoptosis in BGC-823 cells through activating tyrosine kinase, caspase-1, -3, and DFF... - The cross talk between protein kinase A- and RhoA-mediated signaling in cancer cellsYongchang Chen
School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, Jiangsu 212001, China
Exp Biol Med (Maywood) 230:731-41. 2005..The results may be helpful in implementing novel therapeutic strategies for invasive and metastatic prostate and gastric cancers... 
Type II cGMP-dependent protein kinase inhibits proliferation of the gastric cancer cell line BGC-823Yong Chang Chen
School of Medical Science and Laboratory Medicine, Jiangsu University, Jiangsu 212013, P R China
Mol Med Rep 3:361-6. 2010..These data indicate that the activation of PKG II by 8-pCPT-cGMP inhibits the proliferation of human gastric cancer cells...
Localization and translocation of RhoA protein in the human gastric cancer cell line SGC-7901Yan Tao
School of Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, Jiangsu Province, China
World J Gastroenterol 14:1175-81. 2008..To elucidate the localization of RhoA in gastric SGC-7901 cancer cells and its translocation by lysophosphatidic acid (LPA) and/or 8-chlorophenylthio-cAMP (CPT-cAMP)...- Cloning of the nucleostemin gene and its function in transforming human embryonic bone marrow mesenchymal stem cells into F6 tumor cellsChongxu Han
Jiangsu Key Laboratory for Molecular and Medical Biotechnology, School of Life Science, Nanjing Normal University, 112 Ninghai Road, Nanjing, Jiangsu, 210097, China
Int J Mol Med 16:205-13. 2005..These results implied that nucleostemin may play an important role in both tumorigenesis and transforming human embryonic bone marrow mesenchymal stem cells into F6 tumor cells... - Phosphorylated vasodilator-stimulated phosphoprotein is localized on mitotic spindles of the gastric cancer cell line SGC-7901Yan Tao
School of Medicine, Jiangsu University, No 2 Dongwu Road, Zhenjiang 212001, Jiangsu Province, China
World J Gastroenterol 12:7478-81. 2006..To elucidate the localization of vasodilator stimulated phosphoprotein (VASP), a cytoskeletal organizing protein and a substrate of protein kinases A and G in mitotic gastric cancer cells... - Human mesenchymal stem cells isolated from the umbilical cordChun Qiao
School of Medical Technology, Centre for Clinical Laboratory Medicine of Affiliated Hospital, Jiangsu University, Zhenjiang Key Institute of Clinical Laboratory Medicine, 301 Xuefu Road, Zhenjiang, Jiangsu 212013, PR China
Cell Biol Int 32:8-15. 2008..Here we show that umbilical cords may be a novel alternative source of human MSCs for experimental and clinical applications... - Mesenchymal stem cells derived from bone marrow favor tumor cell growth in vivoWei Zhu
School of Medical Technology, Jiangsu University, Zhenjiang, Jiangsu 212001, China
Exp Mol Pathol 80:267-74. 2006..These findings suggested that MSCs could favor tumor growth in vivo. It is necessary to carry out a study for assurance of the long-term safety before MSCs were used as a therapy tools in regenerative medicine and tissue engineering... - Effect of nitric oxide on the proliferation of AGS gastric cancer cellsJian Rong Sang
Department of Physiology, Jiangsu University, Zhenjiang, Jiangsu 212013, PR China
Chin J Cancer 29:158-62. 2010..This study investigated the effect of NO donor sodium nitroprusside (SNP) on the growth and proliferation of gastric cancer cell line AGS... - RhoC protein stimulates migration of gastric cancer cells through interaction with scaffold protein IQGAP1Yan Wu
Jiangsu University, Zhenjiang, Jiangsu 212013, People s Republic of China
Mol Med Report 4:697-703. 2011..These results reveal a previously unrecognized interaction between IQGAP1 and RhoC, and demonstrate that IQGAP1 is a downstream effector of RhoC in the regulation of the migration activity of gastric cancer cells... - A novel tumor cell line cloned from mutated human embryonic bone marrow mesenchymal stem cellsWenrong Xu
School of Medical Technology, Jiangsu University, Zhenjiang, Jiangsu 212001, P R China
Oncol Rep 12:501-8. 2004..These findings suggested that F6 may be a novel tumor cell line. It may provide evidence for the theory that cancer originates from stem cells, and may be useful for the investigation on safety of human MSCs in the clinical application... - Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitroWenrong Xu
School of Life Science, Nanjing Normal University, Nanjing, Jiangsu, 210097, China
Exp Biol Med (Maywood) 229:623-31. 2004..Cardiomyocytes cultured from bone marrow sources are potentially valuable for repairing injured myocardium... - Phosphorylation of vasodilator stimulated phosphoprotein is correlated with cell cycle progression in HeLa cellsYan Tao
School of Medical Science and Laboratory Medicine, Jiangsu University, Jiangsu 212013, P R China
Mol Med Report 3:657-62. 2010..These results suggest that p-VASP S157 may play an important role in the G2/M transition and the completion of cytokinesis in HeLa cells... - LPS-induced nuclear translocation of RhoA is dependent on NF-κB in the human lung cancer cell line A549Yan Tao
School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P R China
Oncol Lett 3:1283-1287. 2012..These results demonstrate that LPS is able to activate RhoA and trigger its nuclear translocation, which is dependent on NF-κB, and that RhoA plays a significant role in the LPS/NF-κB signaling pathway... - Bone marrow mesenchymal stem cells ameliorate rat acute renal failure by differentiation into renal tubular epithelial-like cellsHui Qian
Zhenjiang Key Institute of Clinical Laboratory Medicine, School of Medical Technology, Jiangsu University, Zhenjiang 212013, P R China
Int J Mol Med 22:325-32. 2008..These results demonstrate that cell therapy has potential as a novel intervention in ARF... - Localization of phosphorylated TrkA in carrier vesicles involved in its nuclear translocation in U251 cell lineAihua Gong
School of Medicine, Jiangsu University, Zhenjiang 212013, China
Sci China C Life Sci 50:141-6. 2007..Accordingly, our results suggested that such a series of membrane compartments might be involved in the pathway of nuclear translocation of the transmembrane receptor TrkA... - Histological type of oncogenity and expression of cell cycle genes in tumor cells from human mesenchymal stem cellsRunqiu Jiang
School of Medical Technology, Zhenjiang Key Institute of Clinical Laboratory Medicine, Jiangsu 212001, PR China
Oncol Rep 16:1021-8. 2006.... - Localization of NGF and TrkA at mitotic apparatus in human glioma cell line U251Zhijian Zhang
School of Medicine, Jiangsu University, Jiangsu Zhenjiang 212001, China
Biochem Biophys Res Commun 337:68-74. 2005..The phosphorylated TrkA with the tyrosine kinase activity may phosphorylate the tubulin and promote the mitotic spindle assembly. By these mechanisms, NGF can modulate the mitosis of human glioma cells... - Breviscapine, a traditional Chinese medicine, alleviates myocardial ischaemia reperfusion injury in diabetic ratsJun Hai Jia
Institute of Life Science, Jiangsu University, Zhenjiang, Jiangsu, China
Acta Cardiol 63:757-62. 2008..The aim of this study was to explore the effects of breviscapine on the expressions of intercellular adhesion molecule-I (ICAM-I), ATPase activities and oxidative stress in ischaemia-reperfused (I/R) myocardium of diabetic rats...