Y Wang

Summary

Affiliation: Institute of Vertebrate Paleontology and Paleoanthropology
Country: China

Publications

  1. doi request reprint M129V polymorphism in the prion protein gene is not associated with mesial temporal lobe epilepsy in a Han Chinese population
    X Wang
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China
    Eur J Neurol 15:827-30. 2008
  2. ncbi request reprint An ossified Meckel's cartilage in two Cretaceous mammals and origin of the mammalian middle ear
    Y Wang
    Institute of Vertebrate Paleontology and Paleoanthropology IVPP, Chinese Academy of Sciences, Post Office Box 643, Beijing, 100044, China
    Science 294:357-61. 2001
  3. doi request reprint Paroxysmal kinesigenic choreoathetosis: evidence of linkage to the pericentromeric region of chromosome 16 in four Chinese families
    X Wang
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China
    Eur J Neurol 17:800-7. 2010
  4. doi request reprint Prevention of relapse using granulocyte CSF-primed PBPCs following HLA-mismatched/haploidentical, T-cell-replete hematopoietic SCT in patients with advanced-stage acute leukemia: a retrospective risk-factor analysis
    Y Wang
    Peking University People s Hospital, Institute of Hematology, No 11Xizhimen South Street, Xicheng, Beijing, China
    Bone Marrow Transplant 47:1099-104. 2012
  5. doi request reprint Single-nucleotide polymorphisms in the promoter of the growth hormone-releasing hormone receptor gene are associated with growth and reproduction traits in chickens
    W Liu
    Key Laboratory of Agricultural Animal Genetics and Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China
    Anim Genet 43:564-9. 2012
  6. doi request reprint Basiliximab for the treatment of steroid-refractory acute graft-versus-host disease after unmanipulated HLA-mismatched/haploidentical hematopoietic stem cell transplantation
    J Z Wang
    Peking University People s Hospital, Institute of Hematology, Beijing, China
    Transplant Proc 43:1928-33. 2011
  7. doi request reprint The incidence and risk factors of invasive fungal infection after haploidentical haematopoietic stem cell transplantation without in vitro T-cell depletion
    Y Q Sun
    Peking University People s Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation for the Treatment of Haematological Diseases, Beijing, China
    Clin Microbiol Infect 18:997-1003. 2012
  8. doi request reprint Association study of functional polymorphisms in serotonin transporter gene with temporal lobe epilepsy in Han Chinese population
    J Li
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China
    Eur J Neurol 19:351-3. 2012
  9. pmc A novel family of RGD-containing disintegrins (Tablysin-15) from the salivary gland of the horsefly Tabanus yao targets αIIbβ3 or αVβ3 and inhibits platelet aggregation and angiogenesis
    D Ma
    Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China
    Thromb Haemost 105:1032-45. 2011
  10. ncbi request reprint Gestational hypertension risk evaluation based on epidemiological, biochemical, and hemodynamic factors
    L Yang
    College of Life Science and Bioengineering, Beijing University of Technology, Beijing, China
    Clin Exp Obstet Gynecol 40:61-5. 2013

Collaborators

  • Y Zhang
  • J Wang
  • Jost Jonas
  • Liang Xu
  • M C Marquez
  • Yong Yang
  • L Zhang
  • H Yang
  • C Li
  • Le Xin Wang
  • D Gu
  • J Li
  • W Zhang
  • X Wang
  • Y Chen
  • J Zhang
  • Y Liu
  • D Ma
  • H Wang
  • H Zhang
  • W Liu
  • S Zhu
  • L Liu
  • X Wu
  • Z Wang
  • J Chen
  • W Li
  • X Xu
  • G Chen
  • S Zhang
  • J Yang
  • G Wang
  • J Liu
  • C Chen
  • D Lin
  • D Chen
  • L Yang
  • Z Zhang
  • H Liu
  • X Li
  • M Fan
  • W Sun
  • L Li
  • S Yu
  • X Zhu
  • X Yang
  • T Li
  • Q Zhang
  • X Liu
  • L Wu
  • W Yang
  • Y Sun
  • P Wang
  • T Gui
  • Y Mao
  • T An
  • X Ding
  • Q Wang
  • Y Yu
  • J Shen
  • C Wu
  • X Liang
  • J Qian
  • Ming Rui Huo
  • L Huang
  • S Qiu
  • X Guo
  • G Zhu
  • Z Xu
  • D Li
  • Y Q Sun
  • G He
  • Z Li
  • G X He
  • W Liang
  • G You
  • G Li
  • H Lin
  • Y Zhou
  • Y Zheng
  • G Zhang
  • H Yu
  • G Guo
  • X Ning
  • Y Huang
  • S Liao
  • L Tian
  • L Q Meng
  • R Lai
  • Y Shi

Detail Information

Publications95

  1. doi request reprint M129V polymorphism in the prion protein gene is not associated with mesial temporal lobe epilepsy in a Han Chinese population
    X Wang
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China
    Eur J Neurol 15:827-30. 2008
    ..We screened variations in the open-reading frame (ORF) of the PRNP gene and also replicated the association of the M129V polymorphism with TLE in a Han Chinese population...
  2. ncbi request reprint An ossified Meckel's cartilage in two Cretaceous mammals and origin of the mammalian middle ear
    Y Wang
    Institute of Vertebrate Paleontology and Paleoanthropology IVPP, Chinese Academy of Sciences, Post Office Box 643, Beijing, 100044, China
    Science 294:357-61. 2001
    ..Modifications of both feeding and hearing apparatuses in early mammals may have led to the development of the definitive mammalian middle ear...
  3. doi request reprint Paroxysmal kinesigenic choreoathetosis: evidence of linkage to the pericentromeric region of chromosome 16 in four Chinese families
    X Wang
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China
    Eur J Neurol 17:800-7. 2010
    ..The pericentromeric region of chromosome 16 has been linked to PKC by several reports. This study was to localize and identify PKC gene in four Chinese PKC families...
  4. doi request reprint Prevention of relapse using granulocyte CSF-primed PBPCs following HLA-mismatched/haploidentical, T-cell-replete hematopoietic SCT in patients with advanced-stage acute leukemia: a retrospective risk-factor analysis
    Y Wang
    Peking University People s Hospital, Institute of Hematology, No 11Xizhimen South Street, Xicheng, Beijing, China
    Bone Marrow Transplant 47:1099-104. 2012
    ..002), AML (P=0.027) and female sex (P=0.023). Our results suggest that use of prophylactic GPBPCI may increase survival of patients with advanced-stage acute leukemia who receive HLA-mismatched/haploidentical HSCT...
  5. doi request reprint Single-nucleotide polymorphisms in the promoter of the growth hormone-releasing hormone receptor gene are associated with growth and reproduction traits in chickens
    W Liu
    Key Laboratory of Agricultural Animal Genetics and Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China
    Anim Genet 43:564-9. 2012
    ..05). These results suggest that the three SNPs in the GHRHR promoter could be used as potential genetic markers to improve the growth and reproductive traits in chickens...
  6. doi request reprint Basiliximab for the treatment of steroid-refractory acute graft-versus-host disease after unmanipulated HLA-mismatched/haploidentical hematopoietic stem cell transplantation
    J Z Wang
    Peking University People s Hospital, Institute of Hematology, Beijing, China
    Transplant Proc 43:1928-33. 2011
    ..We investigated the efficacy and safety of the chimeric Mab, basiliximab, to treat steroid-refractory acute GVHD after unmanipulated mismatched/haploidentical HSCT...
  7. doi request reprint The incidence and risk factors of invasive fungal infection after haploidentical haematopoietic stem cell transplantation without in vitro T-cell depletion
    Y Q Sun
    Peking University People s Hospital, Peking University Institute of Haematology, Beijing Key Laboratory of Haematopoietic Stem Cell Transplantation for the Treatment of Haematological Diseases, Beijing, China
    Clin Microbiol Infect 18:997-1003. 2012
    ..48%, 7.86%, 29.6% and 23.1%, respectively. In conclusion, IFI is an important complication following haploidentical HSCT without in vitro T-cell depletion...
  8. doi request reprint Association study of functional polymorphisms in serotonin transporter gene with temporal lobe epilepsy in Han Chinese population
    J Li
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China
    Eur J Neurol 19:351-3. 2012
    ..We investigated the association between three common polymorphisms of 5-HTT gene, which may influence gene expression or function, and risk for TLE...
  9. pmc A novel family of RGD-containing disintegrins (Tablysin-15) from the salivary gland of the horsefly Tabanus yao targets αIIbβ3 or αVβ3 and inhibits platelet aggregation and angiogenesis
    D Ma
    Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China
    Thromb Haemost 105:1032-45. 2011
    ..The RGD motif in the unique sequence of Tablysin-15 represents a novel template for studying the structure-function relationship of the disintegrin family of inhibitors...
  10. ncbi request reprint Gestational hypertension risk evaluation based on epidemiological, biochemical, and hemodynamic factors
    L Yang
    College of Life Science and Bioengineering, Beijing University of Technology, Beijing, China
    Clin Exp Obstet Gynecol 40:61-5. 2013
    ..Gestational hypertension (GH) is a serious health hazard for pregnant women and fetuses. The incidence of GH involves many epidemiological, biochemical, and hemodynamic factors...
  11. doi request reprint c-Abl and Arg tyrosine kinases regulate lysosomal degradation of the oncoprotein Galectin-3
    X Li
    Beijing Institute of Biotechnology, Beijing, China
    Cell Death Differ 17:1277-87. 2010
    ..As tumors frequently overexpress Gal3, a c-Abl/Arg-specific inhibitor may potentially be applied along with other antitumor drugs to target the lysosomal degradation of Gal3 in tumor therapy...
  12. doi request reprint C10ORF97 is a novel tumor-suppressor gene of non-small-cell lung cancer and a functional variant of this gene increases the risk of non-small-cell lung cancer
    Y Shi
    Sino German Laboratory for Molecular Medicine, Key Laboratory for Clinical Cardiovascular Genetics, Ministry of Education, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
    Oncogene 30:4107-17. 2011
    ..73 (95% confidence interval: 1.33-2.25), P=4.6 × 10(-5)). These data indicated that C10ORF97 is a tumor suppressor of NSCLC progression and C10ORF97-SNP216 may serve as a predictor of NSCLC...
  13. doi request reprint Accuracy of genomic prediction for milk production traits in the Chinese Holstein population using a reference population consisting of cows
    X Ding
    Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture of China, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, China
    J Dairy Sci 96:5315-23. 2013
    ..13 to 0.30 and 0.23 to 0.33 higher than the accuracies of conventional pedigree index, respectively. The results indicate that, as an alternative, genomic selection using cows in the reference population is feasible...
  14. doi request reprint Characterization of antimicrobial resistance of Pseudomonas aeruginosa isolated from canine infections
    D Lin
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, China Agricultural University, Beijing, China
    J Appl Microbiol 113:16-23. 2012
    ..To determine the prevalence of Pseudomonas aeruginosa among dogs with suspected soft tissue infections and to characterize these isolates...
  15. doi request reprint Associations of IL-23R polymorphisms with ankylosing spondylitis in East Asian population: a new case-control study and a meta-analysis
    C Chen
    Department of Spinal and Neural Functional Reconstruction, China, Rehabilitation Research Center, Beijing, China
    Int J Immunogenet 39:126-30. 2012
    ..In conclusion, we found no evidence for association between IL-23R and AS in East Asian population. Major attention should be paid to other genes belonged to IL-23 signalling pathway network in the future...
  16. ncbi request reprint Prevalence of diabetes mellitus in China
    L Xu
    Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China
    Exp Clin Endocrinol Diabetes 116:69-70. 2008
    ..To investigate the prevalence of diabetes mellitus in China...
  17. doi request reprint A clinical case-control study on the association between mannose-binding lectin and susceptibility to HIV-1 infection among northern Han Chinese population
    A Sheng
    School of Public Health and Family Medicine, Capital Medical University, Beijing, China
    Int J Immunogenet 37:445-54. 2010
    ..The individuals with B variant, low serum MBL concentration and low MBL complex activity are more susceptible to HIV-1 infection...
  18. doi request reprint Dissemination and characterization of NDM-1-producing Acinetobacter pittii in an intensive care unit in China
    J Yang
    Department of Microbiology, Chinese PLA General Hospital, Beijing, China
    Clin Microbiol Infect 18:E506-13. 2012
    ..pittii isolate. Thus, we present the first report on the transmission and characterization of NDM-1-producing A. pittii in an ICU in China as well as a novel bla(NDM-1) gene-bearing plasmid...
  19. pmc The correlation between T helper type 17 cells and clinical characters in Chinese paediatric patients with chronic hepatitis B
    S Zhu
    Paediatric Liver Disease Therapy and Research Center, 302 Hospital, Beijing, China
    Clin Exp Immunol 171:307-12. 2013
    ..Peripheral Th17 cell frequency is associated closely with inflammation activity of liver tissues in paediatric patients with CHB...
  20. doi request reprint Efficacy and safety of changing from cyclosporine C0 to C2 monitoring in stable recipients following renal transplantation: a prospective cohort study
    Y Zhang
    Urology Department, Beijing Chao Yang Hospital, Capital Medical University, Beijing, China
    Transplant Proc 43:3697-701. 2011
    ..One must be cautious to change from monitoring C0 to C2 in stable recipients following renal transplantation...
  21. doi request reprint Emergence of resistance to fluoroquinolones and third-generation cephalosporins in Shigella flexneri subserotype 1c isolates from China
    S Qiu
    Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China
    Clin Microbiol Infect 18:E95-8. 2012
    ..Overall, the seven isolates showed reduced susceptibility to ciprofloxacin; one isolate was ciprofloxacin resistant, whilst another developed resistance to ciprofloxacin, norfloxacin, cefotaxime and ceftriaxone...
  22. ncbi request reprint Polymorphisms of ACE2 gene are associated with essential hypertension and antihypertensive effects of Captopril in women
    X Fan
    Hypertension Division, Department of Cardiology, Ministry of Education and Sino German Laboratory for Molecular Medicine, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Clin Pharmacol Ther 82:187-96. 2007
    ..3 mm Hg lower in ACE2 T allele carriers than in CC genotype carriers (P=0.019) in women. We conclude that the ACE2 T allele confers a high risk for hypertension and reduced antihypertensive response to ACE inhibitors...
  23. pmc Colitogenic role of tumour necrosis factor (TNF) receptors in trinitrobenzene sulphonic acid colitis: TNF-R1 ablation does not affect systemic inflammatory response
    Y Yang
    Department of Molecular Immunology, Institute of Basic Medical Sciences, Beijing, China
    Clin Exp Immunol 165:372-82. 2011
    ..These findings suggest that either TNF-R1 or TNF-R2 plays a pathogenic role in the pathology of colitis and TNF signalling via TNF-R1 or TNF-R2 alone is not sufficient for inducing mucosal damage...
  24. doi request reprint A high-density single-nucleotide polymorphism screen of 23 candidate genes in attention deficit hyperactivity disorder: suggesting multiple susceptibility genes among Chinese Han population
    L Guan
    Department of Child and Adolescent Psychiatry, Institute of Mental Health, Peking University, Beijing, China
    Mol Psychiatry 14:546-54. 2009
    ..05. This study has identified several genes as promising susceptibility loci for ADHD. Replication efforts and further investigations remain necessary to provide definite proof of association...
  25. doi request reprint Efficacy and safety of short-term administration of recombinant human atrial natriuretic peptide (rhANP) for congestive heart failure: a phase II, multicentre randomized controlled dose-finding study
    P Wang
    State Key Laboratory of Cardiovascular Diseases, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    J Clin Pharm Ther 38:388-93. 2013
    ..This study was designed to assess the efficacy and safety of short-term infusion of recombinant human atrial natriuretic peptide (rhANP) in CHF patients...
  26. doi request reprint COMT rs4680 Met is not always the 'smart allele': Val allele is associated with better working memory and larger hippocampal volume in healthy Chinese
    Y Wang
    State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China
    Genes Brain Behav 12:323-9. 2013
    ..110, t = -2.315, P = 0.021). These results add to the growing literature on differentiated effects of COMT rs4680 polymorphism on WM across populations and offer a brain structural mechanism for such population-specific genetic effects...
  27. doi request reprint Diversity of pneumococcal surface protein A (PspA) and relation to sequence typing in Streptococcus pneumoniae causing invasive disease in Chinese children
    J Qian
    Key Laboratory of Major Diseases in Children and National Key Discipline of Pediatrics Capital Medical University, Ministry of Education, Beijing Pediatric Research Institute, Beijing Children s Hospital, Capital Medical University, Nan Lishi Road, Beijing, 100045, China
    Eur J Clin Microbiol Infect Dis 31:217-23. 2012
    ..5%) were the most common types. PspA family 2 and family 1 were dominant among pneumococcal clones isolated from Chinese children with invasive disease. The strains with the same ST always presented in the same PspA family...
  28. doi request reprint Prevalence of human respiratory viruses in adults with acute respiratory tract infections in Beijing, 2005-2007
    L Ren
    Dr Christophe Mérieux Laboratory, IPB, CAMS Fondation Mérieux and State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology IPB, Chinese Academy of Medical Sciences CAMS, Beijing, China
    Clin Microbiol Infect 15:1146-53. 2009
    ..Currently, this study is the largest-scale investigation of respiratory virus infections in China with multiple agent detection, providing baseline data for further studies of respiratory virus infections in adults with ARTIs...
  29. doi request reprint The CKLF1-C19 peptide attenuates allergic lung inflammation by inhibiting CCR3- and CCR4-mediated chemotaxis in a mouse model of asthma
    L Tian
    Department of Medical Immunology, School of Basic Medical Science, Peking University Health Science Center, 38 Xueyuan Road, Beijing, China
    Allergy 66:287-97. 2011
    ..Albeit with weaker chemotactic activity, C19 can inhibit chemotaxis induced by both CKLF1 and CCL17. Here, we explore whether C19 can act as an antagonist in the development of asthma...
  30. doi request reprint Antibiotic use in pulmonology wards of Chinese children's hospitals: 2002-2006
    W Zhang
    Beijing Children s Hospital, Capital Medical University, Beijing, China
    J Clin Pharm Ther 34:61-5. 2009
    ..To investigate the pattern of antibiotic use in the pulmonology wards of four children's hospitals in China from 2002 to 2006...
  31. doi request reprint Characterization of emm types and superantigens of Streptococcus pyogenes isolates from children during two sampling periods
    Y Ma
    Beijing Children s Hospital, Affiliated to Capital Medical University, Beijing, China
    Epidemiol Infect 137:1414-9. 2009
    ..No significant difference in emm-type distribution and SAg gene profile was noted between isolates from different diseases. These data may contribute towards the development of a GAS vaccine in China...
  32. doi request reprint Treatment of cuff-related tracheal stenosis with a fully covered retrievable expandable metallic stent
    G Chen
    Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
    Clin Radiol 68:358-64. 2013
    ..To investigate the clinical effectiveness, complications, and optimal duration of use of covered retrievable expandable metallic stents in the management of cuff-related tracheal stenosis...
  33. doi request reprint Prohibitins are involved in protease-activated receptor 1-mediated platelet aggregation
    Y Zhang
    Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
    J Thromb Haemost 10:411-8. 2012
    ..The membrane PHBs have been reported to be involved in typhoid fever, obesity, and cancer metastasis. Proteomic studies have revealed the presence of PHBs in human platelets, but the roles of PHBs during platelet aggregation are unknown...
  34. doi request reprint Prevalence and antimicrobial resistance of Enterococcus species of food animal origin from Beijing and Shandong Province, China
    Y Liu
    Beijing Key Laboratory of Detection Technology for Animal Derived Food Safety, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing, China
    J Appl Microbiol 114:555-63. 2013
    ..To evaluate the prevalence and antimicrobial resistance of Enterococcus species from chickens and pigs in Beijing and Shandong Province, China...
  35. ncbi request reprint The effect of obstructive sleep apnea-hypopnea syndrome on acute myocardial infarction
    W Zhang
    Department of Cardiology, Chinese PLA General Hospital, Beijing, China
    Bratisl Lek Listy 113:565-8. 2012
    ..Obstructive sleep apnea-hypopnea syndrome (OSAHS) is the most clinically common type of sleep-related breathing disorders. In this study, the effect of OSAHS on ST segment elevation myocardial infarction (STEMI) was investigated...
  36. doi request reprint The effect of HLA disparity on clinical outcome after HLA-haploidentical blood and marrow transplantation
    Ming Rui Huo
    Peking University People s Hospital, Peking Peking University Institute of Hematology, Beijing, China
    Clin Transplant 26:284-91. 2012
    ..Our results suggest that prospective matching of patients and donors for HLA-B antigen in the unshared HLA haplotype is warranted for HLA-mismatched/haploidentical transplantation...
  37. doi request reprint A Rac1/PAK1 cascade controls β-catenin activation in colon cancer cells
    G Zhu
    Protein Science Laboratory of the Ministry of Education, School of Life Sciences, Tsinghua University, Beijing, China
    Oncogene 31:1001-12. 2012
    ..Supporting this conclusion, overexpression of PAK1 is observed in 70% of colon cancer samples and is correlated with massive β-catenin accumulation...
  38. ncbi request reprint Clinical analysis of elderly patients with elderly-onset type 2 diabetes mellitus in China: assessment of appropriate therapy
    Y Wang
    Department of Geriatrics, Beijing Tong Ren Hospital, Capital Medical University, Beijing, China
    J Int Med Res 38:1134-41. 2010
    ..In conclusion, insulin resistance was less severe in elderly-onset diabetes than in usual-onset diabetes. As hyperglycaemia was relatively mild or moderate, oral hypoglycaemic agents might be effective for elderly-onset diabetes...
  39. ncbi request reprint Genetic diversity and population history of the red panda (Ailurus fulgens) as inferred from mitochondrial DNA sequence variations
    B Su
    Laboratory of Comparative Genomics, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
    Mol Biol Evol 18:1070-6. 2001
    ..Interestingly, the effective population size in the Sichuan population was both larger and more stable than that in the Yunnan population, implying a southward expansion from Sichuan to Yunnan...
  40. ncbi request reprint Increase of the expression of midecamycin 4"-hydroxyl propionyltransferase gene (mpt) by a promoter-like fragment from the midecamycin producing strain
    H Gu
    Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, China
    Chin J Biotechnol 12:147-52. 1996
    ..lividans TK24 up to 89.02% and 58.53%, respectively, and also enhance the expression in the industrial spiramycin producing strain S. spiramyceticus to a great extent...
  41. ncbi request reprint Highly efficient expression of rabbit neutrophil peptide-1 gene in Chlorella ellipsoidea cells
    Y Chen
    Group 603, Institute of Genetics, Chinese Academy of Sciences, Beijing, PR China
    Curr Genet 39:365-70. 2001
    ..Integration of the gene for NP-1 into the Chlorella genome was confirmed by PCR and Southern blot analysis. In, vitro anti-microbial testes demonstrated the expression of biologically active NP-1 by the transgenic Chlorella cells...
  42. ncbi request reprint Enhancement of conflict processing activity in human brain under task relevant condition
    H Wang
    Department of Neurology, Xuanwu Hospital, Capital University of Medical Sciences, 100053, PR, Beijing, China
    Neurosci Lett 298:155-8. 2001
    ..The mean amplitude of the N270 was more negative in task relevant conflict than in irrelevant conflict. Therefore, the conflict processing activity can be initiated independently of the task, but is enhanced in task relevant conflict...
  43. ncbi request reprint Incidence of nonarteritic anterior ischemic optic neuropathy in adult Chinese: the Beijing Eye Study
    L Xu
    Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China
    Eur J Ophthalmol 17:459-60. 2007
    ..To determine the incidence of optic nerve damage due to nonarteritic anterior ischemic optic neuropathy (NAION) in the adult Chinese population...
  44. doi request reprint Comparisons of 5-aminolevulinic acid photodynamic therapy and after-loading radiotherapy in vivo in cervical cancer
    T Gui
    Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100730, China
    Clin Transl Oncol 15:434-42. 2013
    ..To compare the differences between 5-aminolevulinic acid photodynamic therapy (5-ALA-PDT) with traditional after-loading radiotherapy in aspects of efficacies and side effects...
  45. ncbi request reprint Neuregulin-1 protects against doxorubicin-induced apoptosis in cardiomyocytes through an Akt-dependent pathway
    T An
    Heart Failure Center, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Physiol Res 62:379-85. 2013
    ..RhNRG-1 is a novel therapeutic drug which may be effective in preventing further damage from occurring in DOX-induced damaged myocardium. ..
  46. doi request reprint Clinical and molecular genetic factors affecting postoperative seizure control of 183 Chinese adult patients with low-grade gliomas
    G You
    Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
    Eur J Neurol 19:298-306. 2012
    ..Poor seizure control after surgery has a great adverse impact on quality of life in these patients. The present study aimed to identify clinical and molecular genetic factors that influence postoperative seizure control...
  47. doi request reprint Response to the first wave of pandemic (H1N1) 2009: experiences and lessons learnt from China
    W Liang
    Ministry of Health, People s Republic of China, Beijing, China
    Public Health 126:427-36. 2012
    ....
  48. doi request reprint Methicillin-resistant Staphylococcus pseudintermedius isolated from canine pyoderma in North China
    Y Wang
    Beijing Key Laboratory of Detection Technology for Animal Derived Food Safety, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing, China
    J Appl Microbiol 112:623-30. 2012
    ..To determine the prevalence of carriage of methicillin-resistant Staphylococcus pseudintermedius (MRSP) among dogs with pyoderma from two small animal hospitals in North China during a 21-month period and to characterize these isolates...
  49. ncbi request reprint Human insulin from a precursor overexpressed in the methylotrophic yeast Pichia pastoris and a simple procedure for purifying the expression product
    Y Wang
    State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
    Biotechnol Bioeng 73:74-9. 2001
    ..After tryptic transpeptidation, human insulin with full receptor binding capacity and biological activity was obtained. In the presence of zinc, the recombinant human insulin could be crystallized in the rhombohedral form...
  50. ncbi request reprint Study on antifertility effect of a novel LHRH antagonist in male rats
    Y Wang
    National Research Institute for Family Planning, Beijing, China
    Contraception 55:369-72. 1997
    ..Less elongated spermatids were found in the lumen of seminiferous tubules of the treated rats. The size of Leydig cells decreased; psychosis and apoptosis features occurred...
  51. ncbi request reprint Use of Haavikko's method to assess dental age in Chinese children
    Y Wang
    Department of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, China
    Community Dent Health 28:160-4. 2011
    ....
  52. ncbi request reprint Identification of a novel mutation in a Chinese family with X-linked ocular albinism
    Y Wang
    Department of Dermatology, Xuan Wu Hospital, Capital Medical University, Beijing, China
    Eur J Ophthalmol 19:124-8. 2009
    ..The purpose of the study was to evaluate the GPR143 gene (G-protein coupled receptor 143) in a Chinese three-generation family with OA1, including four carriers and a proband with clinical features of X-linked ocular albinism...
  53. ncbi request reprint Prevention of neurotoxin damage of 6-OHDA to dopaminergic nigral neuron by subthalamic nucleus lesions
    L Chen
    Department of Neurosurgery, Navy General Hospital of PLA, Beijing, China
    Stereotact Funct Neurosurg 75:66-75. 2000
    ..To investigate the possibility that subthalamic nucleus (STN) ablation could prevent the toxicity of the selective dopaminergic neurotoxin 6-hydroxydopamine (6-OHDA)...
  54. doi request reprint Docetaxel plus trans-tracheal injection of adenoviral-mediated p53 versus docetaxel alone in patients with previously treated non-small-cell lung cancer
    X Ning
    Department of Medical Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, China
    Cancer Gene Ther 18:444-9. 2011
    ..However, direct trans-tracheal injection of Adp53 proved to be a safe procedure, with tolerable levels of toxicity...
  55. doi request reprint A new method for rapid identification of ansamycin compounds by inactivating KLM gene clusters in potential ansamycin-producing actinomyces
    G Wang
    College of Forest Resources and Environment, Nanjing Forestry University, Nanjing, China
    J Appl Microbiol 112:353-62. 2012
    ....
  56. pmc Canine hip dysplasia is predictable by genotyping
    G Guo
    Department of Animal Science, China Agricultural University, Beijing, China
    Osteoarthritis Cartilage 19:420-9. 2011
    ..To establish a predictive method using whole genome genotyping for early intervention in canine hip dysplasia (CHD) risk management, for the prevention of the progression of secondary osteoarthritis (OA), and for selective breeding...
  57. ncbi request reprint [Effects of grazing and cultivating on emission of nitrous oxide, carbon dioxide and uptake of methane from grasslands]
    Y Wang
    LAPC, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100083, China
    Huan Jing Ke Xue 22:7-13. 2001
    ..It was a fact that N2O and CO2 emission from the soils was inversely related to CH4 uptake...
  58. doi request reprint Evolutionary and functional epitopes of the Spätzle protein: new insights into activation of the Toll receptor
    Y Wang
    Group of Animal Innate Immunity, State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Datun Road, Chaoyang District, Beijing, 100101, China
    Cell Mol Life Sci 66:1595-602. 2009
    ....
  59. doi request reprint Comparative serum proteomic analysis of patients with acute-on-chronic liver failure: alpha-1-acid glycoprotein maybe a candidate marker for prognosis of hepatitis B virus infection
    F Ren
    Beijing Artificial Liver Treatment and Training Centre, Beijing You An Hospital, Affiliated Hospital of Capital Medical University, Beijing, China
    J Viral Hepat 17:816-24. 2010
    ..Our study shows that α1-AGP may be a potential plasma biomarker for AoCLF diagnosis because of acute exacerbation of chronic hepatitis B infection...
  60. doi request reprint Oestrogen-related receptor alpha inverse agonist XCT-790 arrests A549 lung cancer cell population growth by inducing mitochondrial reactive oxygen species production
    J Wang
    Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
    Cell Prolif 43:103-13. 2010
    ..The aim of this study was to investigate any connection between ERRalpha activity and cell population growth...
  61. doi request reprint A novel member of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosis
    Y Wang
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Tsinghua University 5 Dong Dan San Tiao, Beijing, 100005, China
    Cell Mol Life Sci 65:3822-9. 2008
    ..Overexpression or knock-down of RHBDD1 in HEK 293T cells can reduce or enhance BIK-mediated apoptosis, respectively. The present findings suggest that, by acting as a serine protease, RHBDD1 modulates BIK-mediated apoptotic activity...
  62. doi request reprint Risk factors associated with tuberculosis infection among health care workers in Inner Mongolia, China
    G X He
    Chinese Center for Disease Control and Prevention, Beijing, China
    Int J Tuberc Lung Dis 16:1485-91. 2012
    ..In China, surveys examining TB infection among HCWs have not studied general health care facilities, compared tuberculin tests conducted using local protocols against an internationally accepted test or characterised risk factors...
  63. doi request reprint Association of AFLP and SCAR markers with common leafspot resistance in autotetraploid alfalfa (Medicago sativa)
    Y Wang
    Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China
    Genet Mol Res 11:606-16. 2012
    ..Moreover, the genetic analysis indicated that CLS resistance in alfalfa is conferred by a single dominant gene...
  64. ncbi request reprint Topographical distribution pattern of cervical intraepithelial neoplasia across the cervix
    G He
    Department of Obstetrics and Gynaecology, China Japan Friendship Hospital, Beijing, China
    J Int Med Res 40:1897-903. 2012
    ..The distribution of cervical intraepithelial neoplasia (CIN) lesions across the cervix was determined...
  65. ncbi request reprint Prevalence of congenital optic disc pits in adult Chinese: The Beijing Eye Study
    Y Wang
    Beiging Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China
    Eur J Ophthalmol 16:863-4. 2006
    ..4%) with an age of 40+ years. The present study included 4027 (90.7%) subjects for whom readable optic disc photographs were available...
  66. pmc Modelling the transmission dynamics of meticillin-resistant Staphylococcus aureus in Beijing Tongren hospital
    J Wang
    Clinical Laboratory, Beijing Tongren Hospital, Capital Medical University, Beijing, China
    J Hosp Infect 79:302-8. 2011
    ..Therefore, in addition to improving hand hygiene among HCWs, the employment of properly trained volunteers is an attractive alternative to decrease MRSA and other multi-drug resistant bacteria infections in the hospital setting...
  67. ncbi request reprint Emu model of full-range femoral head osteonecrosis induced focally by an alternating freezing and heating insult
    M Fan
    Orthopaedic Research Institute, General Hospital of Chinese People s Liberation Army, Beijing, China
    J Int Med Res 39:187-98. 2011
    ..The protocol resulted in consistent full-range osteonecrosis of the femoral head that may serve as a model for testing potential treatments...
  68. ncbi request reprint EXAFS study on the local atomic structures around iron in glycosylated haemoglobin
    Z Wu
    BSRL, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, People s Republic of China
    Phys Med Biol 46:N71-7. 2001
    ..With increasing of HbA1c concentration, the content of Hb increases and the content of HbO2 decreases. This demonstrates that the glycosylation of haemoglobin will decrease its ability to carry oxygen...
  69. ncbi request reprint Monitoring priority pollutants in a sewage treatment process by dichloromethane extraction and triolein-semipermeable membrane device (SPMD)
    Y Wang
    State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing, People s Republic of China
    Chemosphere 43:339-46. 2001
    ..More attention should be paid to urban sewage treatment process adopting activated-sludge method, where priority organic pollutants might not be removed, even present higher concentrations after treatment...
  70. ncbi request reprint Association study of angiotensin-converting enzyme 2 gene (ACE2) polymorphisms and essential hypertension in northern Han Chinese
    W Huang
    Bioinformatics Laboratory and National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    J Hum Hypertens 20:968-71. 2006
  71. ncbi request reprint Elevated plasma osteopontin level is predictive of cirrhosis in patients with hepatitis B infection
    L Zhao
    State Key Laboratory of Cancer Biology and Institute of Gastroenterology, Xijing Hospital, The Fourth Military Medical University, Xi an, Beijing, China
    Int J Clin Pract 62:1056-62. 2008
    ..However, the significance of OPN in hepatitis B virus (HBV)-induced liver cirrhosis (LC) remains unclear and is therefore evaluated in this study...
  72. ncbi request reprint Uptake of weakly hydrophobic nitroaromatics from water by semipermeable membrane devices (SPMDs) and by goldfish (Carassius auratus)
    Y Wang
    State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing, P R China
    Chemosphere 38:51-66. 1999
    ....
  73. doi request reprint Comparison of vildagliptin and acarbose monotherapy in patients with Type 2 diabetes: a 24-week, double-blind, randomized trial
    C Pan
    Chinese PLA General Hospital, Beijing, China
    Diabet Med 25:435-41. 2008
    ..To compare the efficacy and tolerability of the dipeptidyl peptidase-4 inhibitor, vildagliptin, with the alpha glucosidase inhibitor, acarbose, in drug-naive patients with Type 2 diabetes...
  74. doi request reprint Extended-release doxazosin for treatment of renal transplant recipients with benign prostatic hyperplasia
    Y Zhang
    Urology Department, Capital Medical University, Beijing, China
    Transplant Proc 41:3747-51. 2009
    ..No prisoners were used in the study either as donors or recipients. We sought to assess the effectiveness and safety of extended-release doxazosin for treatment of renal transplant recipients with BPH...
  75. doi request reprint Purification and characterization of two new allergens from the salivary glands of the horsefly, Tabanus yao
    D Ma
    Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
    Allergy 66:101-9. 2011
    ..Horsefly bite can cause allergic reactions in humans. There is no information about allergenic horsefly proteins...
  76. doi request reprint Low-dose MTX combined with low-dose methylprednisolone as a first-line therapy for the treatment of acute GVHD: safety and feasibility
    Y Wang
    Institute of Hematology, Peking University People s Hospital, Beijing, China
    Bone Marrow Transplant 46:892-8. 2011
    ..The estimated survival at 2 years was 77%. From this analysis, MTX in combination with a low dose of MP appears to be a well-tolerated, effective and inexpensive regime when used as a first-line treatment for aGVHD...
  77. doi request reprint Using support vector regression coupled with the genetic algorithm for predicting acute toxicity to the fathead minnow
    Y Wang
    Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
    SAR QSAR Environ Res 21:559-70. 2010
    ..In summary, the successful case reported here highlights that our GA-SVR approach can be used as a general machine learning method for toxicity prediction...
  78. pmc Inclusion of the female condom in a male condom-only intervention in the sex industry in China: a cross-sectional analysis of pre- and post-intervention surveys in three study sites
    S Liao
    Department of Epidemiology and Biostatistics, Institute of Basic Medical Sciences, Peking Union Medical College, China Academy of Medical Sciences, 5 Dong Dan San Tiao, Beijing, China
    Public Health 125:283-92. 2011
    ....
  79. pmc Tunneling-nanotube development in astrocytes depends on p53 activation
    Y Wang
    Laboratory of Neurobiology and State Key Laboratory of Biomembrane and Membrane Biotechnology, College of Life Sciences, Peking University, Beijing, China
    Cell Death Differ 18:732-42. 2011
    ..Akt, phosphoinositide 3-kinase and mTOR are involved in TNT induction. Our data suggest that TNTs might be a mechanism for cells to respond to harmful signals and transfer cellular substances or energy to another cell under stress...
  80. doi request reprint Peer relationships and suicide ideation and attempts among Chinese adolescents
    S Cui
    Department of Child, Adolescent and Women s Health, School of Public Health, Peking University, Beijing, China
    Child Care Health Dev 37:692-702. 2011
    ..We hypothesized that problems in peer relationships were positively associated with suicide ideation and attempts, and that feeling of loneliness would moderate and mediate such associations...
  81. doi request reprint Insight in Chinese schizophrenia patients: a 12-month follow-up
    Y Wang
    Beijing Anding Hospital, Capital Medical University, Beijing, China
    J Psychiatr Ment Health Nurs 18:751-7. 2011
    ..Standard psychiatric care does not improve the level of insight in clinically stable Chinese schizophrenia outpatients, which warrants the introduction of specific therapeutic interventions that enhance insight...
  82. ncbi request reprint Different processes are involved in human brain for shape and face comparisons
    Y Zhang
    Department of Neurology, Xuanwu Hospital, Capital University of Medical Sciences, 100053, Beijing, China
    Neurosci Lett 303:157-60. 2001
    ..2+/-19.8 ms, P4) and N450. There exists a specific system for mismatch processing of a complex stimulus (face) in the human brain...
  83. ncbi request reprint Cloning and expression of L-asparaginase gene in Escherichia coli
    Y Wang
    Department of Enzymology, Institute of Microbiology, Academia Sinica, Beijing, China
    Appl Biochem Biotechnol 95:93-101. 2001
    ..The recombinant plasmid in E. coli AS1.357 remained stable after 72 h of cultivation and 5 h of heat induction without selective pressure. The ASN gene of E. coli AS1.357 was sequenced and had high homology compared to the reported data...
  84. doi request reprint Bioinformatic mining of EST-SSR loci in the Pacific oyster, Crassostrea gigas
    Y Wang
    Laboratory of Marine Bio resource Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China
    Anim Genet 39:287-9. 2008
    ..01), likely due to HWE present in single markers. Cross-species amplification was examined for five other Crassostrea species and reasonable results were obtained, promising usefulness of these markers in oyster genetics...
  85. pmc Astragaloside IV synergizes with ferulic acid to inhibit renal tubulointerstitial fibrosis in rats with obstructive nephropathy
    L Q Meng
    Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China
    Br J Pharmacol 162:1805-18. 2011
    ..In this study, we employed rats with unilateral ureteral obstruction to determine whether AS-IV and FA have the same renoprotective effects and investigated the mechanisms of this action...
  86. doi request reprint Analysis of flavonoids from leaves of cultivated Lycium barbarum L
    Jing Z Dong
    Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, China
    Plant Foods Hum Nutr 64:199-204. 2009
    ..25 mg/g) of cultivated L. barbarum leaves were much higher than those in the wild L. barbarum leaves (17.86 mg/g), so cultivated barbarum leaves are a suitable source for medicine vegetables and functional tea...
  87. ncbi request reprint Storage and dynamics of carbon and nitrogen in soil after grazing exclusion in Leymus chinensis grasslands of northern China
    L Wu
    Key Lab of Vegetation and Environmental Change, Inst of Botany, Chinese Academy of Sciences, Beijing, China
    J Environ Qual 37:663-8. 2008
    ..Our results demonstrated that by implementing GE, the temperate grasslands of northern China could facilitate significant C and N storage on decade scales in the context of mitigating global climate change...
  88. ncbi request reprint Structure effects in angle-resolved high-order above-threshold ionization of molecules
    H Kang
    State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan 430071, China
    Phys Rev Lett 104:203001. 2010
    ....
  89. ncbi request reprint Hydrodynamic characteristics and mixing behaviour of Sclerotium glucanicum culture fluids in an airlift reactor with an internal loop used for scleroglucan production
    X Kang
    State Key Laboratory of Biochemical Engineering, Institute of Chemical Metallurgy, Chinese Academy of Sciences, P.O. Box 353, Beijing 100080, China
    J Ind Microbiol Biotechnol 27:208-14. 2001
    ..The correlations obtained are likely to describe the behaviour of real fungal culture fluids more accurately than previous correlations based on Newtonian or simulated non-Newtonian systems...
  90. ncbi request reprint Genetic diversity of Picea asperata populations based on RAPDs
    X Xue
    Chengdu Institute of Biology, Chinese Academy of Sciences, P O Box 416, Chengdu 610041, China
    Plant Biol (Stuttg) 9:101-8. 2007
    ..In addition, it was discovered that the geographic distribution is not correlated with the genetic distances among the populations of P. asperata...
  91. ncbi request reprint Kashin-Beck disease in children: radiographic findings in the wrist
    W Yu
    Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China
    Skeletal Radiol 31:222-5. 2002
    ....
  92. pmc Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia
    Y Yang
    Department of Dermatology, Peking University First Hospital, Beijing, China
    J Med Genet 41:171-4. 2004
    ..SCN9A, encoding a voltage-gated sodium channel alpha subunit predominantly expressed in sensory and sympathetic neurones, may play an important role in nociception and vasomotor regulation...
  93. ncbi request reprint Assessment of PCBs and PCDD/Fs along the Chinese Bohai Sea coastline using mollusks as bioindicators
    X Zhao
    State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, P O Box 2871, Beijing, 100085, China
    Arch Environ Contam Toxicol 49:178-85. 2005
    ..The results of this study suggest that some gastropod species may be a potential bioindicator or "sentinel" organism for marine PCBs monitoring...
  94. pmc Optic disc size in a population based study in northern China: the Beijing Eye Study
    Y Wang
    Department of Opthalmology and Eye Hospital, Tongren Hospital, Beijing, China
    Br J Ophthalmol 90:353-6. 2006
    ..To determine the optic disc size in the adult Chinese population in an urban and a rural region of Beijing...
  95. ncbi request reprint Peripapillary atrophy in elderly Chinese in rural and urban Beijing
    Y Wang
    Department of Ophthalmology and Eye Hospital, Tongren Hospital, Beijing, China
    Eye (Lond) 22:261-6. 2008
    ..To determine peripapillary atrophy in elderly Chinese in an urban and rural regions of Beijing...