Affiliation: Institute of Zoology
Ma Y, Liu X, Liu Z, Wei S, Shang H, Xue Y, et al
. The Chromatin Remodeling Protein Bptf Promotes Posterior Neuroectodermal Fate by Enhancing Smad2-Activated wnt8a Expression. J Neurosci. 2015;35:8493-506 pubmed publisher
..We propose that Bptf and TGF-Î²/Smad2 mediate nucleosome remodeling to regulate wnt8a expression and hence neural posteriorization. ..
Li L, Mao A, Wang P, Ning G, Cao Y, Wang Q. Endodermal pouch-expressed dmrt2b is important for pharyngeal cartilage formation. Biol Open. 2018;: pubmed publisher
..This work provides insight into how transcription factors expressed in endodermal pouches regulate pharyngeal skeleton development through tissue-tissue interactions. ..
Ma H, Lin Y, Zhao Z, Lu X, Yu Y, Zhang X, et al
. MicroRNA-127 Promotes Mesendoderm Differentiation of Mouse Embryonic Stem Cells by Targeting Left-Right Determination Factor 2. J Biol Chem. 2016;291:12126-35 pubmed publisher
..Altogether, our results indicate that miR-127 accelerates mesendoderm differentiation of mouse embryonic stem cells through nodal signaling by targeting Lefty2. ..
Wei S, Shang H, Cao Y, Wang Q. The coiled-coil domain containing protein Ccdc136b antagonizes maternal Wnt/?-catenin activity during zebrafish dorsoventral axial patterning. J Genet Genomics. 2016;43:431-8 pubmed publisher
Wei S, Ning G, Li L, Yan Y, Yang S, Cao Y, et al
. A GEF activity-independent function for nuclear Net1 in Nodal signal transduction and mesendoderm formation. J Cell Sci. 2017;130:3072-3082 pubmed publisher
..These findings describe a novel genetic mechanism by which nuclear Net1 facilitates Smad2 transcriptional activity to guide mesendoderm development. ..