Tie Shan Tang

Summary

Affiliation: Institute of Zoology
Country: China

Publications

  1. pmc Tetrabenazine is neuroprotective in Huntington's disease mice
    Hongyu Wang
    Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    Mol Neurodegener 5:18. 2010
  2. pmc Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1
    Tie Shan Tang
    Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA
    Neuron 39:227-39. 2003
  3. ncbi REV1 protein interacts with PCNA: significance of the REV1 BRCT domain in vitro and in vivo
    Caixia Guo
    Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Mol Cell 23:265-71. 2006
  4. ncbi Modulation of type 1 inositol (1,4,5)-trisphosphate receptor function by protein kinase a and protein phosphatase 1alpha
    Tie Shan Tang
    Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9040, USA
    J Neurosci 23:403-15. 2003
  5. pmc Ubiquitin-binding motifs in REV1 protein are required for its role in the tolerance of DNA damage
    Caixia Guo
    Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
    Mol Cell Biol 26:8892-900. 2006
  6. ncbi Association of type 1 inositol 1,4,5-trisphosphate receptor with AKAP9 (Yotiao) and protein kinase A
    Huiping Tu
    Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9040, USA
    J Biol Chem 279:19375-82. 2004
  7. ncbi Association of CaV1.3 L-type calcium channels with Shank
    Hua Zhang
    Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    J Neurosci 25:1037-49. 2005
  8. pmc Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease
    Tie Shan Tang
    Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Proc Natl Acad Sci U S A 102:2602-7. 2005
  9. ncbi HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5-trisphosphate-induced Ca release in primary culture of striatal medium spiny neurons
    Tie Shan Tang
    Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    Eur J Neurosci 20:1779-87. 2004
  10. pmc Neuroprotective effects of inositol 1,4,5-trisphosphate receptor C-terminal fragment in a Huntington's disease mouse model
    Tie Shan Tang
    Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    J Neurosci 29:1257-66. 2009

Collaborators

Detail Information

Publications17

  1. pmc Tetrabenazine is neuroprotective in Huntington's disease mice
    Hongyu Wang
    Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    Mol Neurodegener 5:18. 2010
    ..TBZ acts by reducing dopaminergic input to the striatum...
  2. pmc Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1
    Tie Shan Tang
    Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA
    Neuron 39:227-39. 2003
    ..Our findings identify a novel molecular link between Htt and InsP3R1-mediated neuronal Ca2+ signaling and provide an explanation for the derangement of cytosolic Ca2+ signaling in HD patients and mouse models...
  3. ncbi REV1 protein interacts with PCNA: significance of the REV1 BRCT domain in vitro and in vivo
    Caixia Guo
    Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Mol Cell 23:265-71. 2006
    ..In vivo studies in both chicken DT40 cells and yeast directly support the requirement of the BRCT domain of REV1 for cell survival and DNA damage-induced mutagenesis...
  4. ncbi Modulation of type 1 inositol (1,4,5)-trisphosphate receptor function by protein kinase a and protein phosphatase 1alpha
    Tie Shan Tang
    Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9040, USA
    J Neurosci 23:403-15. 2003
    ..Based on these data, we suggest that InsP3R1 may participate in cross talk between cAMP and Ca2+ signaling in the neostriatum and possibly in other regions of the brain...
  5. pmc Ubiquitin-binding motifs in REV1 protein are required for its role in the tolerance of DNA damage
    Caixia Guo
    Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
    Mol Cell Biol 26:8892-900. 2006
    ..In cells exposed to UV radiation, the association of REV1 with replication foci is dependent on functional UBMs. The UBMs of REV1 are shown to contribute to DNA damage tolerance and damage-induced mutagenesis in vivo...
  6. ncbi Association of type 1 inositol 1,4,5-trisphosphate receptor with AKAP9 (Yotiao) and protein kinase A
    Huiping Tu
    Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9040, USA
    J Biol Chem 279:19375-82. 2004
    ..The obtained results advance our understanding of cross-talk between cAMP and InsP(3)/Ca(2+) signaling pathways in the brain...
  7. ncbi Association of CaV1.3 L-type calcium channels with Shank
    Hua Zhang
    Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    J Neurosci 25:1037-49. 2005
    ..3 L-type Ca2+ channels in pCREB signaling...
  8. pmc Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease
    Tie Shan Tang
    Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Proc Natl Acad Sci U S A 102:2602-7. 2005
    ..These findings also suggest that Ca2+ and MPTP blockers may have a therapeutic potential for treatment of HD...
  9. ncbi HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5-trisphosphate-induced Ca release in primary culture of striatal medium spiny neurons
    Tie Shan Tang
    Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    Eur J Neurosci 20:1779-87. 2004
    ..Our present results indicate that HAP1 plays an important role in functional interactions between Htt and InsP3R1...
  10. pmc Neuroprotective effects of inositol 1,4,5-trisphosphate receptor C-terminal fragment in a Huntington's disease mouse model
    Tie Shan Tang
    Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    J Neurosci 29:1257-66. 2009
    ..Our data also support potential use of IC10 peptide as a novel HD therapeutic agent...
  11. pmc Dopaminergic signaling and striatal neurodegeneration in Huntington's disease
    Tie Shan Tang
    Department of Physiology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    J Neurosci 27:7899-910. 2007
    ....
  12. ncbi Dopamine receptor-mediated Ca(2+) signaling in striatal medium spiny neurons
    Tie Shan Tang
    Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9040, USA
    J Biol Chem 279:42082-94. 2004
    ..Our results indicate that, following D1 class DAR activation, InsP(3) and cAMP signaling pathways converge on the type 1 InsP(3) receptor, resulting in Ca(2+) oscillations in MSN...
  13. pmc Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation
    Lingna Lv
    Laboratory of Cancer Genomics and Individualized Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China and Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Nucleic Acids Res 41:10312-22. 2013
    ..Moreover, we observed that MSH2 can facilitate TLS across cyclobutane pyrimidine dimers photoproducts in living cells, presenting a novel role of MSH2 in post-UV cellular responses. ..
  14. ncbi Small-molecule activation of neuronal cell fate
    Jay W Schneider
    Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA
    Nat Chem Biol 4:408-10. 2008
    ..These results provide new tools to explore the epigenetic signaling circuitry specifying neuronal cell fate and new leads for neuro-regenerative drugs...
  15. ncbi Reelin modulates NMDA receptor activity in cortical neurons
    Ying Chen
    Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Neurosci 25:8209-16. 2005
    ..Thus, Reelin may physiologically modulate learning and memory by modulating NMDA receptor functions...
  16. ncbi Requirements for the interaction of mouse Polkappa with ubiquitin and its biological significance
    Caixia Guo
    Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9072, USA
    J Biol Chem 283:4658-64. 2008
    ..However, the ubiquitin-binding motifs do not affect Polkappa half-life. Finally, we have examined levels of Polkappa expression following the exposure of mouse cells to benzo[a]pyrene-dihydrodiol epoxide or UVB radiation...
  17. pmc Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3
    Xi Chen
    Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Neurosci 28:12713-24. 2008
    ..Our results indicate that deranged Ca(2+) signaling may play an important role in SCA3 pathology and that Ca(2+) signaling stabilizers such as dantrolene may be considered as potential therapeutic drugs for treatment of SCA3 patients...