Jian Gong Shi

Summary

Affiliation: Institute of Materia Medica
Country: China

Publications

  1. doi request reprint Cytotoxic triterpenoid glycosides from the roots of Gordonia chrysandra
    Lei Yu
    Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Ministry of Education, Beijing 100050, People s Republic of China
    J Nat Prod 72:866-70. 2009
  2. ncbi request reprint Furostanol oligoglycosides from Asparagus cochinchinensis
    Jian Gong Shi
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Bejing 100050, China
    J Asian Nat Prod Res 6:99-105. 2004
  3. ncbi request reprint [Chemical constituents from tuber of Cremastra appendiculata]
    Wen bin Xia
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing
    Zhongguo Zhong Yao Za Zhi 30:1827-30. 2005
  4. ncbi request reprint Acetylated flavonol diglucosides from Meconopsis quintuplinervia
    Xiao Ya Shang
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Phytochemistry 67:511-5. 2006
  5. ncbi request reprint [Chemical constituents from flower buds of Lonicera japonica]
    Fang Wang
    Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 38:1378-85. 2013
  6. ncbi request reprint [Norisoprenoids from red alga Gymnogongrus flabelliformis]
    Zhao Hui Yuan
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Zhongguo Zhong Yao Za Zhi 31:2046-8. 2006
  7. ncbi request reprint Anti-apoptotic effect of esculin on dopamine-induced cytotoxicity in the human neuroblastoma SH-SY5Y cell line
    Da Long Zhao
    Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine affiliated Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, District Xuanwu, Beijing, China
    Neuropharmacology 53:724-32. 2007
  8. ncbi request reprint In vitro identification of cytochrome P450 isoforms responsible for the metabolism of 1-hydroxyl-2,3,5-trimethoxy-xanthone purified from Halenia elliptica D. Don
    Ru Feng
    State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China
    Chem Biol Interact 210:12-9. 2014
  9. ncbi request reprint [Lignans from Machilus robusta]
    Peng Bin Bu
    State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 38:1740-6. 2013
  10. ncbi request reprint [Chemical constitutents of Bauhinia aurea]
    Xiao Ya Shang
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 31:1953-5. 2006

Collaborators

Detail Information

Publications52

  1. doi request reprint Cytotoxic triterpenoid glycosides from the roots of Gordonia chrysandra
    Lei Yu
    Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Ministry of Education, Beijing 100050, People s Republic of China
    J Nat Prod 72:866-70. 2009
    ..Among these substances, compounds 1, 3, 5, and 6 exhibited cytotoxic activity against several human cancer cell lines, with 3 being the most potent...
  2. ncbi request reprint Furostanol oligoglycosides from Asparagus cochinchinensis
    Jian Gong Shi
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Bejing 100050, China
    J Asian Nat Prod Res 6:99-105. 2004
    ....
  3. ncbi request reprint [Chemical constituents from tuber of Cremastra appendiculata]
    Wen bin Xia
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing
    Zhongguo Zhong Yao Za Zhi 30:1827-30. 2005
    ..To investigate the chemical constituents from the tuber of the planted Cremastra appendiculata...
  4. ncbi request reprint Acetylated flavonol diglucosides from Meconopsis quintuplinervia
    Xiao Ya Shang
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Phytochemistry 67:511-5. 2006
    ..Their structures were determined using chemical and spectroscopic methods including HRFABMS, (1)H-(1)H COSY, HSQC and HMBC experiments...
  5. ncbi request reprint [Chemical constituents from flower buds of Lonicera japonica]
    Fang Wang
    Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 38:1378-85. 2013
    ..These compounds were obtained from this plant for the first time...
  6. ncbi request reprint [Norisoprenoids from red alga Gymnogongrus flabelliformis]
    Zhao Hui Yuan
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Zhongguo Zhong Yao Za Zhi 31:2046-8. 2006
    ..To investigate the chemical constituents of the red alga Gymnogongrus flabelliformis Harv...
  7. ncbi request reprint Anti-apoptotic effect of esculin on dopamine-induced cytotoxicity in the human neuroblastoma SH-SY5Y cell line
    Da Long Zhao
    Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine affiliated Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, District Xuanwu, Beijing, China
    Neuropharmacology 53:724-32. 2007
    ..These data indicate that esculin may provide a useful therapeutic strategy for the treatment of progressive neurodegenerative diseases such as Parkinson's disease (PD)...
  8. ncbi request reprint In vitro identification of cytochrome P450 isoforms responsible for the metabolism of 1-hydroxyl-2,3,5-trimethoxy-xanthone purified from Halenia elliptica D. Don
    Ru Feng
    State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China
    Chem Biol Interact 210:12-9. 2014
    ..This study finally provides evidence of substrate inhibition and metabolism-based drug-drug interaction for the medicinal preparations containing HM-1 used in clinic. ..
  9. ncbi request reprint [Lignans from Machilus robusta]
    Peng Bin Bu
    State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 38:1740-6. 2013
    ..In the preliminary assay, compound 17 showed inhibitory activity against NO secretion of mouse peritoneal macrophages with an inhibition rate of 72.2% at 10 micromol x L(-1)...
  10. ncbi request reprint [Chemical constitutents of Bauhinia aurea]
    Xiao Ya Shang
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 31:1953-5. 2006
    ..To study the chemical constituents of Bauhinia aurea...
  11. ncbi request reprint A unique highly oxygenated pyrano[4,3-c][2]benzopyran-1,6-dione derivative with antioxidant and cytotoxic activities from the fungus Phellinus igniarius
    Ying Wang
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People s Republic of China
    Org Lett 7:1675-8. 2005
    ..Phelligridin G (1) showed antioxidant activity inhibiting rat liver microsomal lipid peroxidation and moderate selective cytotoxic activities against human cancer cell lines...
  12. ncbi request reprint Butanolide derivatives from the bark of Machilus yaoshansis
    Ming tao Liu
    State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    J Asian Nat Prod Res 14:713-20. 2012
    ..Their structures were elucidated by spectroscopic and chemical methods. All the isolates were evaluated for cytotoxic and anti-inflammatory activities...
  13. doi request reprint Methoxylated fatty acids from the bark of Fraxinus sieboldiana
    Sheng Lin
    State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China
    J Asian Nat Prod Res 14:235-43. 2012
    ..Their structures were determined by spectroscopic methods including IR, MS, 1D, and 2D NMR experiments. The 3- or 9-methoxylated fatty acids are reported for the first time in nature...
  14. ncbi request reprint Phelligridimer A, a highly oxygenated and unsaturated 26-membered macrocyclic metabolite with antioxidant activity from the fungus Phellinus igniarius
    Ying Wang
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People s Republic of China
    Org Lett 7:4733-6. 2005
    ..Phelligridimer A showed antioxidant activity (IC50 of 10.2 microM) but was inactive to several human cancer cell lines (IC50 > 50 microM) and enzymes PTP1B (IC50 > 25 microM) and thrombin (IC50 > 10 microM)...
  15. ncbi request reprint Two novel glycosidic triterpene alkaloids from the stem barks of Machilus yaoshansis
    Ming tao Liu
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing, People s Republic of China
    Org Lett 9:129-32. 2007
    ..1 and 2 showed nonselective cytotoxic activities against several human cancer cell lines as well as TNF-alpha secretion inhibitory activities...
  16. ncbi request reprint [Study on chemical constituents in rhizome of Pinellia ternata]
    Ping He
    Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 30:671-4. 2005
    ..To study the chemical constituents in rhizome of Pinellia ternata...
  17. doi request reprint Aromatic glycosides from the flower buds of Lonicera japonica
    Fang Wang
    State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    J Asian Nat Prod Res 15:492-501. 2013
    ....
  18. ncbi request reprint [A new paeoniflorin derivative isolated from the root bark ethanol extract of Paeonia suffruticosa]
    Su Juan Wang
    Institute of Materia Medica, Peking Union Medical University and Chinese Academy of Medical Science, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 30:759-61. 2005
    ..To study the chemical constituents of paeoniflorins from root cortex of the Paeonia suffruticosa...
  19. ncbi request reprint [Studies on chemical constituents of Halenia elliptica guided by in vivo absorption and distribution of the constituents]
    Jie Gao
    Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China
    Yao Xue Xue Bao 39:198-203. 2004
    ..To investigate the chemical constituents of the Tibetan herbal medicine Halenia elliptica by guidance of in vivo absorption and distribution of the constituents...
  20. doi request reprint Chemical constituents of Bauhinia aurea
    Xiao Ya Shang
    State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100050, China
    J Asian Nat Prod Res 14:966-72. 2012
    ..Their structures were determined by spectroscopic and chemical methods...
  21. doi request reprint Triterpenoids from the roots of Pterospermum heterophyllum Hance
    Shuai Li
    Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    J Asian Nat Prod Res 11:652-7. 2009
    ..21, 0.55, 0.40, 0.59, and 0.34 microM, respectively. However, the other compounds were inactive (IC(50)>10 microM)...
  22. ncbi request reprint [Non-alkaloid constituents from a Tibetan medicine Meconopsis quintuplinervia]
    Xiao Ya Shang
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Be iing 100050, China
    Zhongguo Zhong Yao Za Zhi 31:468-71. 2006
    ..To study the chemical constituents of a Tibetan medicine Meconopsis quintuplinervia...
  23. ncbi request reprint Chemical constituents of Pyrrosia petiolosa
    Chun Yang
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    J Asian Nat Prod Res 5:143-50. 2003
    ..Their structures have been elucidated by means of chemical and spectroscopic methods including IR, MS, 1D and 2D NMR techniques...
  24. doi request reprint Enzyme kinetic and molecular docking studies on the metabolic interactions of 1-hydroxy-2,3,5-trimethoxy-xanthone, isolated from Halenia elliptica D. Don, with model probe substrates of human cytochrome P450 enzymes
    Ru Feng
    State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China
    Phytomedicine 19:1125-33. 2012
    ..Molecular docking study confirmed the inhibition modes of HM-1 on these human CYP isoforms...
  25. ncbi request reprint [Dihydroflavonol glycosides and flavan-3-ols from Bauhinia aurea]
    Xiao Ya Shang
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 32:815-8. 2007
    ..To study the chemical constituents of Bauhinia aurea...
  26. ncbi request reprint [Studies on chemical constituents of the brown alga Dictyopteris divaricata]
    Fu Hang Song
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 31:125-8. 2006
    ..To investigate the chemical constituents of the brown alga D. divaricata, and to test cytotoxicities of the purified compounds...
  27. ncbi request reprint Effects of Coeloglossum. viride var. bracteatum extract on memory deficits and pathological changes in senescent mice
    Dan Zhang
    Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Basic Clin Pharmacol Toxicol 98:55-60. 2006
    ..Treatment of CE (2.5, 5 mg.kg(-1)) ameliorated the memory impairment; rectified the biochemistry and neural system changes in mice. These results suggest that CE offers promise as a tool for treatment of senescence-related diseases...
  28. ncbi request reprint [Chemical consitituents from root of Isatis indigotica]
    Xiao liang Wang
    State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 38:1172-82. 2013
    ..06, 6.84, and 8.70 micromol x L(-1), respectively, but other compounds were in-active at a concentration of 1.0 x 10 x (-5) mol x L(-1)...
  29. ncbi request reprint [Studies on chemical constituents from the corm of Cremastra appendiculata]
    Zhen Xue
    Institute of Materia Medica, Chinese Academy of Medial Sciences, Being 100050, China
    Zhongguo Zhong Yao Za Zhi 30:511-3. 2005
    ..To study the chemical constituents of the corm of the planted Cremastra appendiculata...
  30. ncbi request reprint Chemical constituents of the rhizomes of Coeloglossum viride var. bracteatum
    Sheng Yang Huang
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    J Asian Nat Prod Res 6:49-61. 2004
    ....
  31. doi request reprint Glycosides from the bark of Machilus robusta
    Peng Bin Bu
    State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    J Asian Nat Prod Res 15:482-91. 2013
    ....
  32. doi request reprint Phenylpropene diglycosides from the bark of Machilus wangchiana
    Wei Cheng
    State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China
    J Asian Nat Prod Res 14:1046-53. 2012
    ..Their structures were determined by spectroscopic and chemical methods. In the preliminary assay, compounds 2 and 5-8 reduced dl-galactosamine (GalN)-induced hepatocyte (WB-F344 cells) damage with 37-41% inhibitions at 10 μM...
  33. ncbi request reprint Minor constituents from the tubers of Gymnadenia conopsea
    Jia Chen Zi
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    J Asian Nat Prod Res 12:477-84. 2010
    ....
  34. doi request reprint 6,7-di-O-glucopyranosyl-esculetin protects SH-SY5Y cells from dopamine-induced cytotoxicity
    Da Long Zhao
    Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine affiliated Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Eur J Pharmacol 580:329-38. 2008
    ..These data indicate that 6,7-di-O-glucopyranosyl-esculetin may provide a useful therapeutic strategy for the treatment of progressive neurodegenerative diseases such as Parkinson's disease...
  35. ncbi request reprint [Studies on chemical constituents from Tibetan medicine wangla(rhizome of Coeloglossum viride var. bracteatum)]
    Sheng Yang Huang
    Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 27:118-20. 2002
    ..To study the chemical constituents of Tibetan Madicine Wangla...
  36. ncbi request reprint [Chemical constituents from branch of Macaranga adenantha and their TNF-alpha inhibitory activity]
    Ming Ma
    Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 32:1175-9. 2007
    ..To investigate the chemical constituents of the brach of Macaranga adenantha, and evaluate their TNF-alpha inhibitory activity...
  37. ncbi request reprint Structural characterization of flavonol 3,7-di-O-glycosides and determination of the glycosylation position by using negative ion electrospray ionization tandem mass spectrometry
    Keyume Ablajan
    Key Laboratory of Bioactive Substances and Resource Utilization of Chinese Herbal Medicine, Ministry of Education, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    J Mass Spectrom 41:352-60. 2006
    ....
  38. ncbi request reprint [Studies on chemical constitutes of green alga Chaetomorpha basiretorsa and their bioactivity]
    Da Yong Shi
    Department of Natural Products, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 30:1162-5. 2005
    ..To study the chemical constituents of Chaetomorpha basiretorsa and screen for bioactive leading compounds...
  39. ncbi request reprint [Alkaloids from a Tibetan medicine Meconopsis quintuplinervia Regel]
    Xiao Ya Shang
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Yao Xue Xue Bao 38:276-8. 2003
    ..To reinvestigate the chemical constituents of the ethanolic extract of Meconopsis quintuplinervia Regel which is a traditional Tibetan medicine used for treatments of hepatitis, tuberculosis etc....
  40. ncbi request reprint Chemical constituents from the linseed meal
    Li Song
    State Key Laboratory of Bioactive Substance and Function of Natural Medicines, and Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Fitoterapia 97:15-22. 2014
    ..The effect of all the isolates on nitric oxide (NO) generation by stimulated macrophages was evaluated, and none of them showed active. ..
  41. doi request reprint NHBA isolated from Gastrodia elata exerts sedative and hypnotic effects in sodium pentobarbital-treated mice
    Ying Zhang
    State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Pharmacol Biochem Behav 102:450-7. 2012
    ..Altogether, these results indicate that NHBA produces significant sedative and hypnotic effects. Such effects might be mediated by the activation of adenosine A₁/A(2A) receptors and stimulation of the sleep center VLPO...
  42. ncbi request reprint [Coumarins from branch of Fraxinus sieboldiana and their antioxidative activity]
    Sheng Lin
    Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Zhongguo Zhong Yao Za Zhi 33:1708-10. 2008
    ..To investigate the chemical constituents from the branch of Fraxinus sieboldiana, and evaluate their antioxidative activity...
  43. doi request reprint Anthraquinones from the roots of Knoxia valerianoides
    Feng Zhao
    State Key Laboratory of Bioactive Substance and Function of Natural Medicines, and Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China
    J Asian Nat Prod Res 13:1023-9. 2011
    ..Compounds 4 and 5 showed moderate activity against nitrogen oxide production in macrophages induced by lipopolysaccharide, at 10(- 5) M, with inhibition ratios of 50.4 ± 3.6 and 41.7 ± 2.1%, respectively...
  44. ncbi request reprint [Determination of two main components in bark of Paeonia suffruticosa by HPLC]
    Yuan zi Tian
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Befiing 100050, China
    Zhongguo Zhong Yao Za Zhi 30:1265-8. 2005
    ..To establish a HPLC method for determination two constituents in bark of Paeonia Suffuticosa...
  45. ncbi request reprint Structural characterization of steroidal saponins by electrospray ionization and fast-atom bombardment tandem mass spectrometry
    Feng Liang
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Rapid Commun Mass Spectrom 16:1168-73. 2002
    ..All of these compounds produced a major product ion with a stable skeleton structure at m/z 255. The results of this paper can assist structural analysis of mixtures of steroidal saponins...
  46. ncbi request reprint Minor new constituents from Heteroplexis micocephala
    Xiao Na Fan
    Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education of PRC, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Yao Xue Xue Bao 45:82-6. 2010
    ..Their structures were elucidated with spectroscopic data analysis including 2D NMR experiments...
  47. ncbi request reprint Biomimetic synthesis of active isorhapontigenin dimers
    Xian Fen Wang
    a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    J Asian Nat Prod Res 16:511-21. 2014
    ..Compounds 2, 6, and 7 were artificially synthesized for the first time. All the products were evaluated for anti-inflammatory activities. ..
  48. doi request reprint Terpenoids from the tuber of Cremastra appendiculata
    Shuai Li
    Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    J Asian Nat Prod Res 10:685-91. 2008
    ..Compound 3 showed in vitro-selective cytotoxicity against human breast cancer cell lines (MCF-7) with an IC50 of 3.18 microM, but 1 and 2 were inactive (IC50>10 microg/ml)...
  49. ncbi request reprint Phenolic glucosides from Alangium plantanifolium
    Jian Gong Shi
    Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing
    J Asian Nat Prod Res 4:47-51. 2002
    ..The structure of 1 was elucidated to be 1-O-[2-(1-hydroxy-6-oxocyclohex-2-ene-1-carboxymethyl)-phenyl]-4,6-O-[(S)-,4,4',5,5' 6,6'-hexahydroxydiphenoyl]-beta-D-glucopyranose...
  50. ncbi request reprint [Chemical constituents from the linseed meal]
    Li Song
    Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Yao Xue Xue Bao 48:521-5. 2013
    ..Among them, compound 1 is a new compound, and compounds 6, 8 and 10 were isolated from the linseed meal for the first time...
  51. ncbi request reprint [Protective effect of new adenosine analog B2 against serum deprivation-induced PC12 cell injury]
    Jing Sun
    Key Laboratory of Bioactive Substances and Function of Natural Medicine, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    Yao Xue Xue Bao 46:1199-203. 2011
    ..The protective effect of B2 may be related with adenosine A2A receptor. Decrease of serum-deprivation induced ROS formation may also be one of the mechanisms...
  52. doi request reprint In vitro study on metabolite profiles of bioactive xanthones isolated from Halenia elliptica D. Don by high performance liquid chromatography coupled to ion trap time-of-flight mass spectrometry
    Ru Feng
    State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China
    J Pharm Biomed Anal 62:228-34. 2012
    ..The metabolites could be new vasoactive substances. This work will provide a basis for study on the structure-activity relationships of these xanthones and their derivatives from Tibetan herbal in the next work...