Zhihai Qin


Affiliation: Institute of Biophysics
Country: China


  1. Deng H, Song K, Zhang J, Deng L, Dong A, Qin Z. Modulating the rigidity of nanoparticles for tumor penetration. Chem Commun (Camb). 2018;54:3014-3017 pubmed publisher
    ..The rigidity of the nanoparticles was adjusted by the changeable crystallinity of the core, which was altered by varying the ratio of ε-caprolactone and butyl acrylate. ..
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    Chen L, Li J, Wang F, Dai C, Wu F, Liu X, et al. Tie2 Expression on Macrophages Is Required for Blood Vessel Reconstruction and Tumor Relapse after Chemotherapy. Cancer Res. 2016;76:6828-6838 pubmed
    ..Cancer Res; 76(23); 6828-38. ©2016 AACR. ..
  3. Liu X, Zhu L, Wang R, Lou X, Yao X, Ni C, et al. IFNγ inhibits fibroblast-leading tumor cell invasion through downregulating N-cadherin. Biochem Biophys Res Commun. 2019;512:544-551 pubmed publisher
    ..The findings indicate that inflammatory cytokines in the tumor microenvironment may regulate the fibroblast-associated tumor metastasis. ..
  4. Ma J, Xu Y, Zheng Q, Wang Y, Hu M, Ma F, et al. Ligustilide inhibits the activation of cancer-associated fibroblasts. Life Sci. 2019;218:58-64 pubmed publisher
    ..Thus, ligustilide is expected to be a candidate for new antitumor drugs. ..
  5. Ni C, Wang C, Zhang J, Qu L, Liu X, Lu Y, et al. Interferon-γ safeguards blood-brain barrier during experimental autoimmune encephalomyelitis. Am J Pathol. 2014;184:3308-20 pubmed publisher
    ..Taken together, our results show that IFNγ, a pleiotropic proinflammatory cytokine, stabilizes blood-brain barrier integrity and, therefore, prevents brain inflammation during EAE. ..
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    GAO P, Tao N, Ma Q, Fan W, Ni C, Wang H, et al. DH332, a synthetic ?-carboline alkaloid, inhibits B cell lymphoma growth by activation of the caspase family. Asian Pac J Cancer Prev. 2014;15:3901-6 pubmed
    ..DH332 exerts effective antitumor activity in vitro and in vivo, and has the potential to be a promising drug candidate for lymphoma therapy. ..
  7. Chen L, Li J, Zhang J, Dai C, Liu X, Wang J, et al. S100A4 promotes liver fibrosis via activation of hepatic stellate cells. J Hepatol. 2015;62:156-64 pubmed publisher
    ..S100A4 promotes liver fibrosis by activating HSCs, which may represent a potential target for anti-fibrotic therapies. ..
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    Han S, Hu M, Qi G, Ma C, Wang Y, Ma F, et al. Polysaccharides from Polygonatum Inhibit the Proliferation of Prostate Cancer-Associated Fibroblasts. Asian Pac J Cancer Prev. 2016;17:3829-33 pubmed
    ..Polysaccharides from polygonatum stimulate autophagy of prostate-CAFs and inhibits prostate-CAF growth, indicating that a novel anti-cancer strategy involves inhibiting the growth of prostate- CAFs. ..