Taijiao Jiang

Summary

Affiliation: Institute of Biophysics
Country: China

Publications

  1. pmc AVID: an integrative framework for discovering functional relationships among proteins
    Taijiao Jiang
    Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
    BMC Bioinformatics 6:136. 2005
  2. pmc NCACO-score: an effective main-chain dependent scoring function for structure modeling
    Liqing Tian
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    BMC Bioinformatics 12:208. 2011
  3. doi request reprint Improved side-chain modeling by coupling clash-detection guided iterative search with rotamer relaxation
    Yang Cao
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Bioinformatics 27:785-90. 2011
  4. pmc Incorporation of local structural preference potential improves fold recognition
    Yun Hu
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 6:e17215. 2011
  5. doi request reprint RASP: rapid modeling of protein side chain conformations
    Zhichao Miao
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
    Bioinformatics 27:3117-22. 2011
  6. doi request reprint A computationally guided protein-interaction screen uncovers coiled-coil interactions involved in vesicular trafficking
    Hong Zhang
    Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    J Mol Biol 392:228-41. 2009
  7. pmc Coiled-coil networking shapes cell molecular machinery
    Yongqiang Wang
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Mol Biol Cell 23:3911-22. 2012
  8. pmc Rapid estimation of binding activity of influenza virus hemagglutinin to human and avian receptors
    Yang Cao
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 6:e18664. 2011
  9. doi request reprint Mapping of H3N2 influenza antigenic evolution in China reveals a strategy for vaccine strain recommendation
    Xiangjun Du
    Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Nat Commun 3:709. 2012
  10. doi request reprint Conjugating drug candidates to polymeric chains does not necessarily enhance anti-influenza activity
    Alyssa M Larson
    Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Pharm Sci 101:3896-905. 2012

Collaborators

  • Yang Cao
  • Hong Zhang
  • Yun Hu
  • Yi Lu
  • Xiao Yang
  • Min Wang
  • Zhuo Wang
  • Xiangjun Du
  • Aiping Wu
  • Alyssa M Larson
  • Yongqiang Wang
  • Xiaoxi Dong
  • Liqing Tian
  • Zhichao Miao
  • Haiying Hang
  • Li Li Zhao
  • Jiuhong Dong
  • Jianzhu Chen
  • Ye Zhang
  • Haolong Huang
  • Yu Lan
  • Yousong Peng
  • Jinan Chen
  • Yuelong Shu
  • Hongmei Wang
  • Libo Dong
  • Alexander M Klibanov
  • Xinlei Zhang
  • Yuanji Guo
  • Dayan Wang
  • Weijuan Huang
  • Zhi Qi
  • Li Jun Bi
  • Pei Liu
  • Xian En Zhang
  • Gang Jin
  • Lin Song

Detail Information

Publications13

  1. pmc AVID: an integrative framework for discovering functional relationships among proteins
    Taijiao Jiang
    Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
    BMC Bioinformatics 6:136. 2005
    ..An outstanding and important goal is to predict detailed functional annotation for all uncharacterized proteins that is reliable enough to effectively guide experiments...
  2. pmc NCACO-score: an effective main-chain dependent scoring function for structure modeling
    Liqing Tian
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    BMC Bioinformatics 12:208. 2011
    ..Despite these efforts, development of an effective scoring function that can achieve both good accuracy and fast speed still presents a grand challenge...
  3. doi request reprint Improved side-chain modeling by coupling clash-detection guided iterative search with rotamer relaxation
    Yang Cao
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Bioinformatics 27:785-90. 2011
    ..However, in the tightly packed environments of protein interiors, these methods will inherently lead to atomic clashes and hinder the prediction accuracy...
  4. pmc Incorporation of local structural preference potential improves fold recognition
    Yun Hu
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 6:e17215. 2011
    ....
  5. doi request reprint RASP: rapid modeling of protein side chain conformations
    Zhichao Miao
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
    Bioinformatics 27:3117-22. 2011
    ..In comprehensive benchmark testings, RASP is over one order of magnitude faster (~ 40 times over CIS-RR) than the recently developed methods, while achieving comparable or even better accuracy...
  6. doi request reprint A computationally guided protein-interaction screen uncovers coiled-coil interactions involved in vesicular trafficking
    Hong Zhang
    Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    J Mol Biol 392:228-41. 2009
    ..Our method provides an efficient route to discovering new coiled-coil interactions and uncovers a number of associations that may have functional significance for vesicular trafficking...
  7. pmc Coiled-coil networking shapes cell molecular machinery
    Yongqiang Wang
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Mol Biol Cell 23:3911-22. 2012
    ....
  8. pmc Rapid estimation of binding activity of influenza virus hemagglutinin to human and avian receptors
    Yang Cao
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 6:e18664. 2011
    ..The new computational method could provide an urgently needed tool for rapid and large-scale analysis of HA receptor specificities for global influenza surveillance...
  9. doi request reprint Mapping of H3N2 influenza antigenic evolution in China reveals a strategy for vaccine strain recommendation
    Xiangjun Du
    Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Nat Commun 3:709. 2012
    ..Furthermore, we demonstrate that the coupling of large-scale HA sequencing with PREDAC can significantly improve vaccine strain recommendation for China...
  10. doi request reprint Conjugating drug candidates to polymeric chains does not necessarily enhance anti-influenza activity
    Alyssa M Larson
    Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Pharm Sci 101:3896-905. 2012
    ..These observations, further explored by means of molecular modeling, reveal the previously unrecognized unpredictability of the benefits of multivalency, possibly because of poor accessibility of the viral targets to polymeric agents...
  11. doi request reprint Synthetic circuits, devices and modules
    Hong Zhang
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
    Protein Cell 1:974-8. 2010
    ..Such engineered basic building blocks largely expand the synthetic toolbox and contribute to our understanding of the underlying design principles of living cells...
  12. doi request reprint Length-dependent regulation of the Kv1.2 channel activation by its C-terminus
    Li Li Zhao
    State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China
    Mol Membr Biol 26:186-93. 2009
    ..2 channel. These results imply that the dynamic interaction of the C-terminus with the S4-S5 linker from a neighboring subunit of the Kv1.2 channel provides a mechanism for its C-terminus to regulate the channel activation...
  13. pmc Networks of genomic co-occurrence capture characteristics of human influenza A (H3N2) evolution
    Xiangjun Du
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
    Genome Res 18:178-87. 2008
    ..Therefore, our study demonstrates that nucleotide co-occurrence networks represent a powerful method for tracking influenza A virus evolution and that cooperative genomic interaction is a major force underlying influenza virus evolution...