Taijiao Jiang

Summary

Affiliation: Institute of Biophysics
Country: China

Publications

  1. pmc AVID: an integrative framework for discovering functional relationships among proteins
    Taijiao Jiang
    Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
    BMC Bioinformatics 6:136. 2005
  2. pmc Rapid estimation of binding activity of influenza virus hemagglutinin to human and avian receptors
    Yang Cao
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 6:e18664. 2011
  3. pmc Incorporation of local structural preference potential improves fold recognition
    Yun Hu
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 6:e17215. 2011
  4. doi request reprint Improved side-chain modeling by coupling clash-detection guided iterative search with rotamer relaxation
    Yang Cao
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Bioinformatics 27:785-90. 2011
  5. pmc Coiled-coil networking shapes cell molecular machinery
    Yongqiang Wang
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Mol Biol Cell 23:3911-22. 2012
  6. doi request reprint A computationally guided protein-interaction screen uncovers coiled-coil interactions involved in vesicular trafficking
    Hong Zhang
    Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    J Mol Biol 392:228-41. 2009
  7. doi request reprint Mapping of H3N2 influenza antigenic evolution in China reveals a strategy for vaccine strain recommendation
    Xiangjun Du
    Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Nat Commun 3:709. 2012
  8. pmc NCACO-score: an effective main-chain dependent scoring function for structure modeling
    Liqing Tian
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    BMC Bioinformatics 12:208. 2011
  9. ncbi request reprint A peptide derived from the C-terminus of PB1 inhibits influenza virus replication by interfering with viral polymerase assembly
    Chunfeng Li
    Key Laboratory of Protein and Peptide Pharmaceutical, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    FEBS J 280:1139-49. 2013
  10. doi request reprint RASP: rapid modeling of protein side chain conformations
    Zhichao Miao
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
    Bioinformatics 27:3117-22. 2011

Collaborators

Detail Information

Publications21

  1. pmc AVID: an integrative framework for discovering functional relationships among proteins
    Taijiao Jiang
    Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
    BMC Bioinformatics 6:136. 2005
    ..An outstanding and important goal is to predict detailed functional annotation for all uncharacterized proteins that is reliable enough to effectively guide experiments...
  2. pmc Rapid estimation of binding activity of influenza virus hemagglutinin to human and avian receptors
    Yang Cao
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 6:e18664. 2011
    ..The new computational method could provide an urgently needed tool for rapid and large-scale analysis of HA receptor specificities for global influenza surveillance...
  3. pmc Incorporation of local structural preference potential improves fold recognition
    Yun Hu
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 6:e17215. 2011
    ....
  4. doi request reprint Improved side-chain modeling by coupling clash-detection guided iterative search with rotamer relaxation
    Yang Cao
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Bioinformatics 27:785-90. 2011
    ..However, in the tightly packed environments of protein interiors, these methods will inherently lead to atomic clashes and hinder the prediction accuracy...
  5. pmc Coiled-coil networking shapes cell molecular machinery
    Yongqiang Wang
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Mol Biol Cell 23:3911-22. 2012
    ....
  6. doi request reprint A computationally guided protein-interaction screen uncovers coiled-coil interactions involved in vesicular trafficking
    Hong Zhang
    Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    J Mol Biol 392:228-41. 2009
    ..Our method provides an efficient route to discovering new coiled-coil interactions and uncovers a number of associations that may have functional significance for vesicular trafficking...
  7. doi request reprint Mapping of H3N2 influenza antigenic evolution in China reveals a strategy for vaccine strain recommendation
    Xiangjun Du
    Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Nat Commun 3:709. 2012
    ..Furthermore, we demonstrate that the coupling of large-scale HA sequencing with PREDAC can significantly improve vaccine strain recommendation for China...
  8. pmc NCACO-score: an effective main-chain dependent scoring function for structure modeling
    Liqing Tian
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    BMC Bioinformatics 12:208. 2011
    ..Despite these efforts, development of an effective scoring function that can achieve both good accuracy and fast speed still presents a grand challenge...
  9. ncbi request reprint A peptide derived from the C-terminus of PB1 inhibits influenza virus replication by interfering with viral polymerase assembly
    Chunfeng Li
    Key Laboratory of Protein and Peptide Pharmaceutical, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    FEBS J 280:1139-49. 2013
    ..The characterization of the inhibitory effect of PB1(731-757) on viral polymerase activity and viral replication could offer a potential target for anti-influenza drug development...
  10. doi request reprint RASP: rapid modeling of protein side chain conformations
    Zhichao Miao
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
    Bioinformatics 27:3117-22. 2011
    ..However, these recent efforts to enhance the quality of predicted side chains have been accompanied by a significant increase of computational cost...
  11. ncbi request reprint Sequential reassortments underlie diverse influenza H7N9 genotypes in China
    Aiping Wu
    Key Laboratory of Protein and Peptide Pharmaceutical, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
    Cell Host Microbe 14:446-52. 2013
    ..Our study identifies the pathways for the generation of diverse H7N9 genotypes in China and highlights the importance of monitoring multiple sources for effective surveillance of potential influenza outbreaks. ..
  12. doi request reprint Conjugating drug candidates to polymeric chains does not necessarily enhance anti-influenza activity
    Alyssa M Larson
    Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Pharm Sci 101:3896-905. 2012
    ..These observations, further explored by means of molecular modeling, reveal the previously unrecognized unpredictability of the benefits of multivalency, possibly because of poor accessibility of the viral targets to polymeric agents...
  13. pmc Analysis of interactions between SNARE proteins using imaging ellipsometer coupled with microfluidic array
    Cai Qi
    1 Institute of Biophysics, Chinese Academy of Sciences, 15, Datun Rd, Beijing, 100101, China 2 Institute of Equipment Technology, Chinese Academy of Inspection and Quarantine, 3, Gaobeidian North Rd, Beijing, 100123, China 3
    Sci Rep 4:5341. 2014
    ..We argue that the use of imaging ellipsometer coupled with microfluidic device will deepen our understanding of the molecular mechanisms underlying membrane fusion process. ..
  14. doi request reprint Modeling of protein side-chain conformations with RASP
    Zhichao Miao
    Key Lab of Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Methods Mol Biol 1137:43-53. 2014
    ..Then details on how to use RASP programs to predict protein side-chain conformations are elaborated. Finally, it describes case studies for structure refinement in homology modeling and residue substitution. ..
  15. doi request reprint Pseudovirus-based neuraminidase inhibition assays reveal potential H5N1 drug-resistant mutations
    Yi Lu
    Key Laboratory of Protein and Peptide Pharmaceuticals, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
    Protein Cell 4:356-63. 2013
    ..Thus, H5N1 NA pseudoviruses could be used to monitor HPAI H5N1 drug resistance rapidly and safely...
  16. pmc Networks of genomic co-occurrence capture characteristics of human influenza A (H3N2) evolution
    Xiangjun Du
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
    Genome Res 18:178-87. 2008
    ..Therefore, our study demonstrates that nucleotide co-occurrence networks represent a powerful method for tracking influenza A virus evolution and that cooperative genomic interaction is a major force underlying influenza virus evolution...
  17. ncbi request reprint Length-dependent regulation of the Kv1.2 channel activation by its C-terminus
    Li Li Zhao
    State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China
    Mol Membr Biol 26:186-93. 2009
    ..2 channel. These results imply that the dynamic interaction of the C-terminus with the S4-S5 linker from a neighboring subunit of the Kv1.2 channel provides a mechanism for its C-terminus to regulate the channel activation...
  18. doi request reprint Synthetic circuits, devices and modules
    Hong Zhang
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
    Protein Cell 1:974-8. 2010
    ..Such engineered basic building blocks largely expand the synthetic toolbox and contribute to our understanding of the underlying design principles of living cells...
  19. doi request reprint A comprehensive surveillance of adamantane resistance among human influenza A virus isolated from mainland China between 1956 and 2009
    Yu Lan
    Chinese National Influenza Center, National Institute for Viral Disease Control and Prevention, China CDC, Beijing, China
    Antivir Ther 15:853-9. 2010
    ..Here, we retrospectively assessed adamantane resistance among different influenza A subtypes (H1N1, H3N2 and H5N1) over 53 years (1956-2009) in mainland China...
  20. pmc Improvement in low-homology template-based modeling by employing a model evaluation method with focus on topology
    Wentao Dai
    Key Laboratory of Protein and Peptide Pharmaceuticals, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China University of the Chinese Academy of Sciences, Beijing, China
    PLoS ONE 9:e89935. 2014
    ..The softwares (FR-t5-M and MEFTop) are available to non-commercial users at our website: http://jianglab.ibp.ac.cn/lims/FRt5M/FRt5M.html. ..