Xun Huang

Summary

Affiliation: Institute of Genetics and Developmental Biology
Country: China

Publications

  1. doi request reprint New players in the regulation of ecdysone biosynthesis
    Xun Huang
    Laboratory of Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
    J Genet Genomics 35:1-10. 2008
  2. ncbi request reprint Opposite and redundant roles of the two Drosophila perilipins in lipid mobilization
    Junfeng Bi
    State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
    J Cell Sci 125:3568-77. 2012
  3. pmc Membrane phospholipid asymmetry counters the adverse effects of sterol overloading in the Golgi membrane of Drosophila
    Zhiguo Ma
    State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
    Genetics 190:1299-308. 2012
  4. pmc Rab32 is important for autophagy and lipid storage in Drosophila
    Chao Wang
    State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 7:e32086. 2012
  5. doi request reprint Lipid metabolism and Drosophila sperm development
    Chao Wang
    State Key Laboratory of Molecular Developmental Biology Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
    Sci China Life Sci 55:35-40. 2012
  6. doi request reprint Lipid metabolism in Drosophila: development and disease
    Zhonghua Liu
    State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
    Acta Biochim Biophys Sin (Shanghai) 45:44-50. 2013
  7. pmc Neuronal target identification requires AHA-1-mediated fine-tuning of Wnt signaling in C. elegans
    Jingyan Zhang
    State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
    PLoS Genet 9:e1003618. 2013
  8. pmc Proteomic study and marker protein identification of Caenorhabditis elegans lipid droplets
    Peng Zhang
    Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China
    Mol Cell Proteomics 11:317-28. 2012
  9. pmc Midlife gene expressions identify modulators of aging through dietary interventions
    Bing Zhou
    Chinese Academy of Sciences Key Laboratory for Computational Biology, Chinese Academy of Sciences Max Planck Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
    Proc Natl Acad Sci U S A 109:E1201-9. 2012
  10. pmc Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation
    Yuan Tian
    Key Laboratory of Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
    PLoS Genet 7:e1001364. 2011

Collaborators

Detail Information

Publications11

  1. doi request reprint New players in the regulation of ecdysone biosynthesis
    Xun Huang
    Laboratory of Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
    J Genet Genomics 35:1-10. 2008
    ..Here we summarized recent findings in the regulation of ecdysone biosynthesis from the aspects of cell signaling, key biosynthetic enzymes and substrate cholesterol trafficking...
  2. ncbi request reprint Opposite and redundant roles of the two Drosophila perilipins in lipid mobilization
    Junfeng Bi
    State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
    J Cell Sci 125:3568-77. 2012
    ..Our study highlights the complex roles of Drosophila perilipin proteins and the evolutionarily conserved regulation of HSL translocation by perilipins...
  3. pmc Membrane phospholipid asymmetry counters the adverse effects of sterol overloading in the Golgi membrane of Drosophila
    Zhiguo Ma
    State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
    Genetics 190:1299-308. 2012
    ....
  4. pmc Rab32 is important for autophagy and lipid storage in Drosophila
    Chao Wang
    State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 7:e32086. 2012
    ..Loss-of-function mutants of several components in the autophagy pathway result in similar effects on lipid storage. These results highlight the potential functions of Rabs in regulating lipid metabolism...
  5. doi request reprint Lipid metabolism and Drosophila sperm development
    Chao Wang
    State Key Laboratory of Molecular Developmental Biology Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
    Sci China Life Sci 55:35-40. 2012
    ..In this mini-review, we summarized recent findings supporting a tight link between lipids metabolism and Drosophila sperm development...
  6. doi request reprint Lipid metabolism in Drosophila: development and disease
    Zhonghua Liu
    State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
    Acta Biochim Biophys Sin (Shanghai) 45:44-50. 2013
    ..Some recent progresses of lipid metabolic regulation during Drosophila development and in Drosophila models of human diseases will be discussed in this review...
  7. pmc Neuronal target identification requires AHA-1-mediated fine-tuning of Wnt signaling in C. elegans
    Jingyan Zhang
    State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
    PLoS Genet 9:e1003618. 2013
    ..Our study reveals a Wnt-dependent fine-tuning mechanism that is crucial for mutual target cell identification during the formation of gap junction connections. ..
  8. pmc Proteomic study and marker protein identification of Caenorhabditis elegans lipid droplets
    Peng Zhang
    Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China
    Mol Cell Proteomics 11:317-28. 2012
    ..elegans LDs, indicating that it can be used as a LD marker protein in C. elegans. These results will facilitate further mechanistic studies of LDs in this powerful genetic system, C. elegans...
  9. pmc Midlife gene expressions identify modulators of aging through dietary interventions
    Bing Zhou
    Chinese Academy of Sciences Key Laboratory for Computational Biology, Chinese Academy of Sciences Max Planck Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
    Proc Natl Acad Sci U S A 109:E1201-9. 2012
    ....
  10. pmc Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation
    Yuan Tian
    Key Laboratory of Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
    PLoS Genet 7:e1001364. 2011
    ..In summary, we have demonstrated a tissue-autonomous role of dSeipin in ectopic lipid storage in lipodystrophy...
  11. doi request reprint The cholesterol trafficking protein NPC1 is required for Drosophila spermatogenesis
    Chao Wang
    Key Laboratory of Molecular and Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
    Dev Biol 351:146-55. 2011
    ..Together, our study reveals a sterol-dependent, ecdysone-independent mechanism of NPC1 function in Drosophila spermatogenesis...