Baidong Hou

Summary

Affiliation: Institute of Biophysics
Country: China

Publications

  1. pmc Critical coordination of innate immune defense against Toxoplasma gondii by dendritic cells responding via their Toll-like receptors
    Baidong Hou
    Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 108:278-83. 2011
  2. pmc Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response
    Baidong Hou
    Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
    Immunity 34:375-84. 2011
  3. pmc Normal development and activation but altered cytokine production of Fyn-deficient CD4+ T cells
    Alusha A Mamchak
    Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
    J Immunol 181:5374-85. 2008
  4. pmc Contribution of Toll-like receptor signaling to germinal center antibody responses
    Anthony L DeFranco
    Department of Microbiology and Immunology, University of California, San Francisco, CA 94143 0414, USA
    Immunol Rev 247:64-72. 2012
  5. pmc Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis
    Gianna Elena Hammer
    Department of Medicine, University of California at San Francisco, San Francisco, California, USA
    Nat Immunol 12:1184-93. 2011
  6. pmc Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms
    Baidong Hou
    Department of Microbiology and Immunology, University of California, San Francisco, CA, 94143, USA
    Immunity 29:272-82. 2008

Collaborators

Detail Information

Publications6

  1. pmc Critical coordination of innate immune defense against Toxoplasma gondii by dendritic cells responding via their Toll-like receptors
    Baidong Hou
    Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 108:278-83. 2011
    ..These results demonstrate a central role of DCs in orchestrating the innate immune response to an intracellular pathogen and establish that defects in pathogen recognition by DCs can predetermine sensitivity to infection...
  2. pmc Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response
    Baidong Hou
    Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
    Immunity 34:375-84. 2011
    ..The ability of B cells to discriminate between antigens based on the physical form of a TLR ligand probably reflects an adaptation to facilitate strong antiviral antibody responses...
  3. pmc Normal development and activation but altered cytokine production of Fyn-deficient CD4+ T cells
    Alusha A Mamchak
    Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
    J Immunol 181:5374-85. 2008
    ..These data demonstrate that ablation of Fyn expression does not alter most Ag-driven CD4(+) T cell responses, with the exception of cytokine production, which under some circumstances is enhanced in Fyn-deficient CD4(+) T cells...
  4. pmc Contribution of Toll-like receptor signaling to germinal center antibody responses
    Anthony L DeFranco
    Department of Microbiology and Immunology, University of California, San Francisco, CA 94143 0414, USA
    Immunol Rev 247:64-72. 2012
    ..This review summarizes recent advances in understanding the roles of TLRs in B cells and also in other cell types for enhancement of antibody responses, with an emphasis on T-cell-dependent and germinal center antibody responses...
  5. pmc Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis
    Gianna Elena Hammer
    Department of Medicine, University of California at San Francisco, San Francisco, California, USA
    Nat Immunol 12:1184-93. 2011
    ..Our findings indicate that DCs need A20 to preserve immune quiescence and suggest that A20-dependent DC functions may underlie IBD and IBD-associated arthritides...
  6. pmc Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms
    Baidong Hou
    Department of Microbiology and Immunology, University of California, San Francisco, CA, 94143, USA
    Immunity 29:272-82. 2008
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