Research Topics


Xuezhen Zhang


Affiliation: Huazhong Agricultural University
Country: China


  1. Zhang X, Xie P, Li D, Tang R, Lei H, Zhao Y. Time-dependent oxidative stress responses of crucian carp (Carassius auratus) to intraperitoneal injection of extracted microcystins. Bull Environ Contam Toxicol. 2009;82:574-8 pubmed publisher
    ..These zigzag changes over time contributed a better understanding on oxidative stress caused by microcystins in fish. ..
  2. Yin J, Wang L, Chen Y, Zhang D, Hegazy A, Zhang X. A comparison of accumulation and depuration effect of dissolved hexavalent chromium (Cr6+) in head and muscle of bighead carp (Aristichthys nobilis) and assessment of the potential health risk for consumers. Food Chem. 2019;286:388-394 pubmed publisher
    ..The Cr6+ levels determined in tissues can tell a real story rather than the correlation coefficient. Fish head poses a higher potential health risk than muscle due to heavy metals pollution. ..
  3. Li J, Chen C, Zhang T, Liu W, Wang L, Chen Y, et al. ╬╝Evaluation of microcystin-LR absorption using an in vivo intestine model and its effect on zebrafish intestine. Aquat Toxicol. 2019;206:186-194 pubmed publisher
  4. Huang X, Chen L, Liu W, Qiao Q, Wu K, Wen J, et al. Involvement of oxidative stress and cytoskeletal disruption in microcystin-induced apoptosis in CIK cells. Aquat Toxicol. 2015;165:41-50 pubmed publisher
    ..Our data suggest that oxidative stress and cytoskeletal disruption may interact with each other and jointly lead to apoptosis and renal toxicity induced by MCs. ..
  5. Xia H, Song T, Wang L, Jiang L, Zhou Q, Wang W, et al. Effects of dietary toxic cyanobacteria and ammonia exposure on immune function of blunt snout bream (Megalabrama amblycephala). Fish Shellfish Immunol. 2018;78:383-391 pubmed publisher
    ..Our data clearly demonstrated that dietary toxic cyanobacteria combined with ammonia exposure showed a synergistic effect on Megalobrama amblycephala immunotoxicity. ..
  6. Chen L, Chen J, Zhang X, Xie P. A review of reproductive toxicity of microcystins. J Hazard Mater. 2016;301:381-99 pubmed publisher
    ..Parental exposure to MCs may result in hepatotoxicity and neurotoxicity of offspring. We also summarize the current research gaps which should be addressed by further studies. ..
  7. Chen Y, Li J, Wei J, Kawan A, Wang L, Zhang X. Vitamin C modulates Microcystis aeruginosa death and toxin release by induced Fenton reaction. J Hazard Mater. 2017;321:888-895 pubmed publisher
    ..This study highlights the possible benefits of using a vitamin C-induced Fenton reaction to remove M. aeruginosa and microcystins from drinking water sources. ..
  8. Chen C, Liu W, Wang L, Li J, Chen Y, Jin J, et al. Pathological damage and immunomodulatory effects of zebrafish exposed to microcystin-LR. Toxicon. 2016;118:13-20 pubmed publisher
    ..Our findings provided strong evidence of the recovery potential of fish exposed to microcystins. ..