Xiaoping Zhang


Affiliation: Huazhong University of Science and Technology
Country: China


  1. Wang X, Chen X, Han W, Ruan A, Chen L, Wang R, et al. miR-200c Targets CDK2 and Suppresses Tumorigenesis in Renal Cell Carcinoma. Mol Cancer Res. 2015;13:1567-77 pubmed publisher
    ..miR-200c exerts its novel antioncogenic function in renal cell carcinoma by controlling CDK2-dependent cell growth and cell-cycle progression. ..
  2. Sun J, Song Z, Zhang X, Xiao X. Efficacy and Safety of COX-2 Inhibitor Parecoxib for Rigid Cystoscopy-related Pain Management in Male Patients: A Prospective, Randomized and Controlled Study. Curr Med Sci. 2019;39:94-98 pubmed publisher
    ..78). No difference was observed in analgesic-related complications between the two groups. We conclude that intramuscular injection of 40 mg parecoxib may improve comfort for male patients undergoing rigid cystoscopy. ..
  3. Ruan H, Bao L, Song Z, Wang K, Cao Q, Tong J, et al. High expression of TAZ serves as a novel prognostic biomarker and drives cancer progression in renal cancer. Exp Cell Res. 2019;376:181-191 pubmed publisher
    ..In conclusion, our results suggest that TAZ may serve as a promising diagnostic and prognostic molecular marker for patients with renal cancer. Moreover, TAZ may represent a novel clinical therapeutic target. ..
  4. Wang K, Xu T, Ruan H, Xiao H, Liu J, Song Z, et al. LXRα promotes cell metastasis by regulating the NLRP3 inflammasome in renal cell carcinoma. Cell Death Dis. 2019;10:159 pubmed publisher
    ..In Brief, LXRα had the possibility to be a novel diagnostic and prognostic biomarker and therapeutic target in renal cell cancer and LXRα could regulate the metastasis of renal cell cancer via NLRP3 inflammamsome. ..
  5. Song Z, Cao Q, Ruan H, Yang H, Wang K, Bao L, et al. RCAN1.4 acts as a suppressor of cancer progression and sunitinib resistance in clear cell renal cell carcinoma. Exp Cell Res. 2018;372:118-128 pubmed publisher
    ..Taken together, these findings indicate that downregulation of RCAN1.4 may be crucial for the metastasis of ccRCC and may induce sunitinib resistance. RCAN1.4 may act as a prognostic indicator and potential therapeutic target for ccRCC. ..
  6. Wang K, Ruan H, Song Z, Cao Q, Bao L, Liu D, et al. PLIN3 is up-regulated and correlates with poor prognosis in clear cell renal cell carcinoma. Urol Oncol. 2018;36:343.e9-343.e19 pubmed publisher
    ..PLIN3 is highly expressed in kidney cancer, and high expression of PLIN3 can serve as a useful diagnostic and prognostic biomarker. PLIN3 functional inhibition can be used as a new clinical treatment option. ..
  7. Shi H, Yu H, Bellmunt J, Leow J, Chen X, Guo C, et al. Comparison of health-related quality of life (HRQoL) between ileal conduit diversion and orthotopic neobladder based on validated questionnaires: a systematic review and meta-analysis. Qual Life Res. 2018;27:2759-2775 pubmed publisher
    ..Regardless of the type of urinary diversion (UD) surgery, a gradual improvement in HRQoL over preoperative status tended to stabilise after 12 months postoperatively. ..
  8. Lou N, Ruan A, Qiu B, Bao L, Xu Y, Zhao Y, et al. miR-144-3p as a novel plasma diagnostic biomarker for clear cell renal cell carcinoma. Urol Oncol. 2017;35:36.e7-36.e14 pubmed publisher
    ..Our data indicate that miR-144-3p, which is significantly up-regulated in ccRCC plasmas and tissues, particularly with advanced pT stage, is a novel and excellent plasma biomarker for the diagnosis of ccRCC. ..
  9. Zhou Y, Zhao Y, Gao Y, Hu W, Qu Y, Lou N, et al. Hepatitis C virus NS3 protein enhances hepatocellular carcinoma cell invasion by promoting PPM1A ubiquitination and degradation. J Exp Clin Cancer Res. 2017;36:42 pubmed publisher

More Information


  1. Ruan H, Li X, Yang H, Song Z, Tong J, Cao Q, et al. Enhanced expression of caveolin-1 possesses diagnostic and prognostic value and promotes cell migration, invasion and sunitinib resistance in the clear cell renal cell carcinoma. Exp Cell Res. 2017;358:269-278 pubmed publisher
  2. Xu G, Lou N, Shi H, Xu Y, Ruan H, Xiao W, et al. Up-regulation of SR-BI promotes progression and serves as a prognostic biomarker in clear cell renal cell carcinoma. BMC Cancer. 2018;18:88 pubmed publisher
    ..Our results demonstrate that SR-BI functions as an oncogene and promotes progression of ccRCC. SR-BI may serve as a potential prognostic biomarker and therapeutic target for ccRCC. ..