Zhi Luo

Summary

Affiliation: Huazhong Agricultural University
Country: China

Publications

  1. Zhang D, Cheng J, Tai Z, Luo Z. Identification of five genes in endoplasmic reticulum (ER) stress-apoptosis pathways in yellow catfish Pelteobagrus fulvidraco and their transcriptional responses to dietary lipid levels. Fish Physiol Biochem. 2019;: pubmed publisher
  2. Pan Y, Zhuo M, Li D, Xu Y, Wu K, Luo Z. SREBP-1 and LXRα pathways mediated Cu-induced hepatic lipid metabolism in zebrafish Danio rerio. Chemosphere. 2019;215:370-379 pubmed publisher
  3. Cui H, Chen Q, Tan X, Zhang D, Ling S, Chen G, et al. MiR-205 Mediated Cu-Induced Lipid Accumulation in Yellow Catfish Pelteobagrus fulvidraco. Int J Mol Sci. 2018;19: pubmed publisher
    ..LXR antagonist effectively ameliorate the Cu-induced change of TG content and FAS activity. These data suggest that down-regulation of the miRNA-205 may be an important step in Cu-induced changes in lipid metabolism in yellow catfish. ..
  4. Li D, Luo Z, Ling S, Wu K, Chen G, Cheng J. Mitochondrial apoptotic pathway mediated the Zn-induced lipolysis in yellow catfish Peteobagrus fulvidraco. Chemosphere. 2018;208:907-915 pubmed publisher
    ..Taken together, our study demonstrated the importance of mitochondria-mediated apoptosis in Zn-induced lipolysis, which suggested a new mechanism for elucidating metal element influencing lipid metabolism. ..
  5. Song Y, Xu Y, Zhuo M, Wu K, Luo Z. CREB element is essential for unfolded protein response (UPR) mediating the Cu-induced changes of hepatic lipogenic metabolism in Chinese yellow catfish (Pelteobagrus fulvidraco). Aquat Toxicol. 2018;203:69-79 pubmed publisher
    ..Taken together, the present study indicated that CREB was essential for UPR mediating Cu-induced lipogenic metabolism, supporting a mechanistic link among CREB, UPR and Cu-induced changes of lipid metabolism. ..
  6. Song Y, Gao Y, Hogstrand C, Li D, Pan Y, Luo Z. Upstream regulators of apoptosis mediates methionine-induced changes of lipid metabolism. Cell Signal. 2018;51:176-190 pubmed publisher
  7. Chen G, Luo Z, Hogstrand C, Wu K, Ling S. SREBP1, PPARG and AMPK pathways mediated the Cu-induced change in intestinal lipogenesis and lipid transport of yellow catfish Pelteobagrus fulvidraco. Food Chem. 2018;269:595-602 pubmed publisher
    ..The PPARG, SREBP1 and AMPK signaling pathways mediated the Cu-induced changes in lipogenesis, lipid uptake and lipid transport in the intestine of yellow catfish. ..
  8. Song Y, Luo Z, Pan Y, Zhang L, Chen Q, Zheng J. Three unsaturated fatty acid biosynthesis-related genes in yellow catfish Pelteobagrus fulvidraco: Molecular characterization, tissue expression and transcriptional regulation by leptin. Gene. 2015;563:1-9 pubmed publisher
  9. Zheng J, Zhuo M, Luo Z, Song Y, Pan Y, Huang C, et al. Peroxisome proliferator-activated receptor alpha1 in yellow catfish Pelteobagrus fulvidraco: molecular characterization, mRNA tissue expression and transcriptional regulation by insulin in vivo and in vitro. Comp Biochem Physiol B Biochem Mol Biol. 2015;183:58-66 pubmed publisher

More Information

Publications42

  1. Chen G, Luo Z, Wei C, Li D, Pan Y. Six indicator genes for zinc (Zn) homeostasis in freshwater teleost yellow catfish Pelteobagrus fulvidraco: molecular characterization, mRNA tissue expression and transcriptional changes to Zn exposure. Biometals. 2018;31:527-537 pubmed publisher
    ..Our study built good basis for further investigating their physiological functions of these genes and provided new insights into the regulatory mechanisms of Zn homeostasis in fish. ..
  2. Chen Q, Luo Z, Liu C, Zheng J, Zhu Q, Hu W, et al. Effects of waterborne copper exposure on carnitine composition, kinetics of carnitine palmitoyltransferases I (CPT I) and mRNA levels of CPT I isoforms in yellow catfish Pelteobagrus fulvidraco. Chemosphere. 2015;139:349-57 pubmed publisher
  3. Chen Q, Luo Z, Liu C, Zheng J. Differential effects of dietary Cu deficiency and excess on carnitine status, kinetics and expression of CPT I in liver and muscle of yellow catfish Pelteobagrus fulvidraco. Comp Biochem Physiol B Biochem Mol Biol. 2015;188:24-30 pubmed publisher
  4. Chen Q, Luo Z, Shi X, Wu K, Zhuo M, Song Y, et al. Dietary methimazole-induced hypothyroidism reduces hepatic lipid deposition by down-regulating lipogenesis and up-regulating lipolysis in Pelteobagrus fulvidraco. Gen Comp Endocrinol. 2015;217-218:28-36 pubmed publisher
  5. Zheng J, Zhuo M, Luo Z, Pan Y, Song Y, Huang C, et al. Peroxisome proliferator-activated receptor gamma (PPARγ) in yellow catfish Pelteobagrus fulvidraco: molecular characterization, mRNA expression and transcriptional regulation by insulin in vivo and in vitro. Gen Comp Endocrinol. 2015;212:51-62 pubmed publisher
  6. Hu W, Luo Z, Mai K, Liu C, Zheng J. Ontogeny and kinetics of carnitine palmitoyltransferase I in hepatopancreas and skeletal muscle of grass carp (Ctenopharyngodon idella). Fish Physiol Biochem. 2015;41:1393-401 pubmed publisher
  7. Chen Q, Luo Z, Wu K, Huang C, Zhuo M, Song Y, et al. Differential effects of dietary copper deficiency and excess on lipid metabolism in yellow catfish Pelteobagrus fulvidraco. Comp Biochem Physiol B Biochem Mol Biol. 2015;184:19-28 pubmed publisher
    ..Different response patterns of enzymatic activities and gene expression in various tissues following dietary Cu levels indicated the tissue-specific regulatory effect by Cu. ..
  8. Zheng J, Luo Z, Zhu Q, Hu W, Zhuo M, Pan Y, et al. Different effect of dietborne and waterborne Zn exposure on lipid deposition and metabolism in juvenile yellow catfish Pelteobagrus fulvidraco. Aquat Toxicol. 2015;159:90-8 pubmed publisher
    ..For the first time, our study demonstrates the differential effect of different Zn exposure pathways on lipid metabolism at the molecular level in fish, indicating that the exposure route is critical to lipid deposition and metabolism. ..
  9. Pan Y, Luo Z, Zhuo M, Wei C, Chen G, Song Y. Oxidative stress and mitochondrial dysfunction mediated Cd-induced hepatic lipid accumulation in zebrafish Danio rerio. Aquat Toxicol. 2018;199:12-20 pubmed publisher
  10. Chen F, Huang C, Luo Z, Shi X, Liu X, Fan Y, et al. Fe reduced hepatic lipid deposition in Synechogobius hasta exposed to waterborne Cu. Aquat Toxicol. 2016;174:134-45 pubmed publisher
    ..Different response patterns of these enzyme activities and gene expressions in the liver of S. hasta following waterborne Fe exposure indicated that Fe effects on Cu-induced change of lipid metabolism are time-dependent. ..
  11. Chen F, Luo Z, Fan Y, Wu K, Pan Y, Liu X, et al. Five metal elements homeostasis-related genes in Synechogobius hasta: Molecular characterization, tissue expression and transcriptional response to Cu and Fe exposure. Chemosphere. 2016;159:392-402 pubmed publisher
  12. Luo Z, Wei C, Ye H, Zhao H, Song Y, Wu K. Effect of dietary choline levels on growth performance, lipid deposition and metabolism in juvenile yellow catfish Pelteobagrus fulvidraco. Comp Biochem Physiol B Biochem Mol Biol. 2016;202:1-7 pubmed publisher
    ..To our knowledge, this is the first to explore the effect of dietary choline level on mRNA expression of these genes, which provides new insights into choline nutrition in fish. ..
  13. Chen F, Luo Z, Chen G, Shi X, Liu X, Song Y, et al. Effects of waterborne Cu exposure on intestinal copper transport and lipid metabolism of Synechogobius hasta. Aquat Toxicol. 2016;178:171-81 pubmed publisher
    ..To our knowledge, this is the first report involved in intestinal lipid metabolism in combination with intestinal Cu absorption following waterborne Cu exposure, which provides new insights and evidence into Cu toxicity in fish. ..
  14. Song Y, Luo Z, Huang C, Chen Q, Pan Y, Xu Y. Endoplasmic Reticulum Stress-Related Genes in Yellow Catfish Pelteobagrus fulvidraco: Molecular Characterization, Tissue Expression, and Expression Responses to Dietary Copper Deficiency and Excess. G3 (Bethesda). 2015;5:2091-104 pubmed publisher
  15. Wu K, Zheng J, Luo Z, Chen Q, Zhu Q, Wei Hu -. Carnitine palmitoyltransferase I gene in Synechogobius hasta: Cloning, mRNA expression and transcriptional regulation by insulin in vitro. Gene. 2016;576:429-40 pubmed publisher
  16. Pan Y, Luo Z, Wu K, Zhang L, Xu Y, Chen Q. Cloning, mRNA expression and transcriptional regulation of five retinoid X receptor subtypes in yellow catfish Pelteobagrus fulvidraco by insulin. Gen Comp Endocrinol. 2016;225:133-141 pubmed publisher
    ..fulvidraco, respectively, suggesting that Pf-rxrgb is the dominant rxr subtype involved in the insulin signaling pathway in P. fulvidraco. ..
  17. Hu W, Mai K, Luo Z, Zheng J, Huang C, Pan Y. Effect of waterborne zinc exposure on lipid deposition and metabolism in hepatopancreas and muscle of grass carp Ctenopharyngodon idella. Fish Physiol Biochem. 2016;42:1093-105 pubmed publisher
    ..Differential patterns of lipid deposition, enzymatic activities and genes' expression indicate the tissue-specific regulatory mechanism in fish. ..
  18. Zhuo M, Luo Z, Xu Y, Li D, Pan Y, Wu K. Functional Analysis of Promoters from Three Subtypes of the PI3K Family and Their Roles in the Regulation of Lipid Metabolism by Insulin in Yellow Catfish Pelteobagrus fulvidraco. Int J Mol Sci. 2018;19: pubmed publisher
    ..Thus, the present study offers new insights into the mechanisms for transcriptional regulation of PI3Ks and for PI3Ks-mediated regulation of lipid metabolism by insulin in fish. ..
  19. Zhang L, Luo Z, Song Y, Shi X, Pan Y, Fan Y, et al. Effects and mechanisms of waterborne copper exposure influencing ovary development and related hormones secretion in yellow catfish Pelteobagrus fulvidraco. Aquat Toxicol. 2016;178:88-98 pubmed publisher
    ..fulvidraco, which will help to understand the Cu-induced reproductive toxicity at both protein and transcriptional levels in fish. ..
  20. Zhuo M, Luo Z, Pan Y, Wu K, Fan Y, Zhang L, et al. Effects of insulin and its related signaling pathways on lipid metabolism in the yellow catfish Pelteobagrus fulvidraco. J Exp Biol. 2015;218:3083-90 pubmed publisher
    ..The present results contribute new knowledge on the regulatory role of insulin in hepatic metabolism in fish. ..
  21. Song Y, Luo Z, Zhang L, Hogstrand C, Pan Y. Endoplasmic reticulum stress and disturbed calcium homeostasis are involved in copper-induced alteration in hepatic lipid metabolism in yellow catfish Pelteobagrus fulvidraco. Chemosphere. 2016;144:2443-53 pubmed publisher
  22. Ling S, Luo Z, Chen G, Zhang D, Liu X. Waterborne Zn influenced Zn uptake and lipid metabolism in two intestinal regions of juvenile goby Synechogobius hasta. Ecotoxicol Environ Saf. 2018;148:578-584 pubmed publisher
    ..Our results, for the first time, show an anterior/mid functional regionalization of the intestine in lipid metabolism and Zn transport of S. hasta following Zn exposure. ..
  23. Xu Y, Luo Z, Wu K, Fan Y, You W, Zhang L. Structure and Functional Analysis of Promoters from Two Liver Isoforms of CPT I in Grass Carp Ctenopharyngodon idella. Int J Mol Sci. 2017;18: pubmed publisher
    ..All of these results provided new insights into the mechanisms for transcriptional regulation of CPT I genes in fish. ..
  24. Li D, Luo Z, Chen G, Song Y, Wei C, Pan Y. Identification of apoptosis-related genes Bcl2 and Bax from yellow catfish Pelteobagrus fulvidraco and their transcriptional responses to waterborne and dietborne zinc exposure. Gene. 2017;633:1-8 pubmed publisher
  25. Chen G, Luo Z, Chen F, Shi X, Song Y, You W, et al. PPAR?, PPAR? and SREBP-1 pathways mediated waterborne iron (Fe)-induced reduction in hepatic lipid deposition of javelin goby Synechogobius hasta. Comp Biochem Physiol C Toxicol Pharmacol. 2017;197:8-18 pubmed publisher
    ..hasta. ..
  26. Zhuo M, Pan Y, Wu K, Xu Y, Zhang L, Luo Z. IRS1 and IRS2: molecular characterization, tissue expression and transcriptional regulation by insulin in yellow catfish Pelteobagrus fulvidraco. Fish Physiol Biochem. 2017;43:619-630 pubmed publisher
    ..The present study serves to increase our understanding into the function of IRS in fish. ..
  27. Cheng J, Luo Z, Chen G, Wei C, Zhuo M. Identification of eight copper (Cu) uptake related genes from yellow catfish Pelteobagrus fulvidraco, and their tissue expression and transcriptional responses to dietborne Cu exposure. J Trace Elem Med Biol. 2017;44:256-265 pubmed publisher
  28. Song Y, Hogstrand C, Wei C, Wu K, Pan Y, Luo Z. Endoplasmic reticulum (ER) stress and cAMP/PKA pathway mediated Zn-induced hepatic lipolysis. Environ Pollut. 2017;228:256-264 pubmed publisher
    ..Taken together, our findings highlight the importance of the ER stress-cAMP/PKA axis in Zn-induced lipolysis, which provides new insights into Zn toxicology in fish and probably in other vertebrates. ..
  29. Wei C, Wu K, Gao Y, Zhang L, Li D, Luo Z. Magnesium Reduces Hepatic Lipid Accumulation in Yellow Catfish (Pelteobagrus fulvidraco) and Modulates Lipogenesis and Lipolysis via PPARA, JAK-STAT, and AMPK Pathways in Hepatocytes. J Nutr. 2017;147:1070-1078 pubmed publisher
    ..PPARA, JAK-STAT, and AMPK pathways mediated the magnesium-induced changes in lipid deposition and metabolism. These results offer new insight into magnesium nutrition in vertebrates. ..
  30. Zhuo M, Pan Y, Wu K, Xu Y, Luo Z. Characterization and mechanism of phosphoinositide 3-kinases (PI3Ks) members in insulin-induced changes of protein metabolism in yellow catfish Pelteobagrus fulvidraco. Gen Comp Endocrinol. 2017;247:34-45 pubmed publisher
    ..Thus, our study demonstrated that among seven PI3K members, PI3KCb and PI3KC2a were more sensitive to the insulin signaling pathway, and insulin stimulated hepatic protein synthesis in yellow catfish through PI3K signaling pathway. ..
  31. Wei C, Luo Z, Song Y, Pan Y, Wu K, You W. Identification of autophagy related genes LC3 and ATG4 from yellow catfish Pelteobagrus fulvidraco and their transcriptional responses to waterborne and dietborne zinc exposure. Chemosphere. 2017;175:228-238 pubmed publisher
  32. Pan Y, Luo Z, Zhuo M, Hu W, Wu K, Shi X, et al. Liver X Receptor (LXR) in yellow catfish Pelteobagrus fulvidraco: Molecular characterization, mRNA tissue expression and transcriptional regulation by insulin in vivo and in vitro. Comp Biochem Physiol B Biochem Mol Biol. 2016;191:13-9 pubmed publisher
    ..The present study serves to increase our understanding into the function of lxra in fish. ..
  33. Zhuo M, Pan Y, Wu K, Xu Y, Zhang L, Luo Z. AKTs/PKBs: molecular characterization, tissue expression and transcriptional responses to insulin and/or wortmannin in yellow catfish Pelteobagrus fulvidraco. Fish Physiol Biochem. 2017;43:719-730 pubmed publisher