Research Topics
| Qiang HuangSummaryCountry: China Publications
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Detail Information
Publications
Development of clinically relevant orthotopic xenograft mouse model of metastatic lung cancer and glioblastoma through surgical tumor tissues injection with trocarXi Feng Fei
Neurosurgical Department, Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, 188 Shizi Street, 215006, Suzhou, China
J Exp Clin Cancer Res 29:84. 2010..Orthotopic models are important in cancer research. Here we developed orthotopic xenograft mouse model of metastatic lung cancer and glioblastoma with a specially designed system...
Glioma stem cells are more aggressive in recurrent tumors with malignant progression than in the primary tumor, and both can be maintained long-term in vitroQiang Huang
Department of Neurosurgery and Brain Tumor Research Laboratory, Second Affiliated Hospital of Suzhou University, Suzhou 215004, PR China
BMC Cancer 8:304. 2008..Research on GSCs is still in its infancy, so no definitive conclusions about their role can yet be drawn. To understand the biology of GSCs fully, it is highly desirable to establish permanent and biologically stable GSC lines...
Overexpression of CDC2/CyclinB1 in gliomas, and CDC2 depletion inhibits proliferation of human glioma cells in vitro and in vivoHua Chen
Department of Neurosurgery and Brain Tumor Research Laboratory, 2nd Affiliated Hospital, Soochow University, Suzhou, China
BMC Cancer 8:29. 2008....
Differentiation profile of brain tumor stem cells: a comparative study with neural stem cellsQuan Bin Zhang
Neurosurgical Department and Brain Tumor Research Laboratory, Second Affiliated Hospital of Suzhou University, Suzhou 215004, China
Cell Res 16:909-15. 2006..Taken together, BTSCs were revealed to possess a capacity to resist differentiation, which actually represents the malignant behaviors of glioma...
[Transplantation of human glioma stem cells in nude mice with green fluorescent protein expression]Zi cheng Wu
Department of Neurosurgery, Second Affiliated Hospital of Suzhou University, Suzhou 215004, China
Zhonghua Yi Xue Za Zhi 88:2317-20. 2008..To investigate the possibility of transplantation of human glioma stem cells (HGSCs) in nude mice stably expressing green fluorescent protein (GFP) so as to clearly identify the incubated HGSCs from the host tissues...
[Experimental study of combination therapy against human glioma xenograft by differentiation-inducing agent and cytotoxic chemotherapeutic drug]Ming gang Shi
Department of Neurosurgery, Brain Tumor Research Laboratory, Second Affiliated Hospital of Suzhou University, Suzhou 215004, P R China
Ai Zheng 21:1090-4. 2002..This study was designed to investigate anti-tumor effects of differentiation-inducing agent in combination with cytotoxic chemotherapeutic drug against glioma...
[Characteristics of morphology, differentiation related marker, and proliferation dynamics of differentiated brain tumor stem cells in vitro]Xiao-yan Ji
Department of Neurosurgery and Brain Tumor Research Laboratory, Second Affiliated Hospital of Soochow University, Suzhou 215004, China
Zhonghua Yi Xue Za Zhi 86:1604-9. 2006..Most of the NSCs were G(0)-G(1) phase cells. CONCLUSION: The differentiation direction of BTSCs is quietly different from that of the NSCs. There is an obvious dysdifferentiation in BTSCs...
[Microsurgical treatment of complex intracranial aneurysms via keyhole approaches]Qing Lan
Department of Neurosurgery, Second Affiliated Hospital of Suzhou University, Suzhou 215004, China
Zhonghua Yi Xue Za Zhi 87:872-6. 2007..To explore the feasibility and effect of microsurgical treatment of complex intracranial aneurysms via keyhole approaches...
