Research Topics

Li Guo


Country: China


  1. Guo L, Yang Q, Lu J, Li H, Ge Q, Gu W, et al. A comprehensive survey of miRNA repertoire and 3' addition events in the placentas of patients with pre-eclampsia from high-throughput sequencing. PLoS ONE. 2011;6:e21072 pubmed publisher
    ..The study enriches association of miRNAs and human disease, including potential roles of various miRNA variants and 3' addition events. ..
  2. Guo L, Lu Z. Global expression analysis of miRNA gene cluster and family based on isomiRs from deep sequencing data. Comput Biol Chem. 2010;34:165-71 pubmed publisher
  3. Guo L, Zhao Y, Yang S, Zhang H, Wu Q, Chen F. An integrated evolutionary analysis of miRNA-lncRNA in mammals. Mol Biol Rep. 2014;41:201-7 pubmed publisher
    ..The phylogenetical conservation of the imprinted cluster may be also derived from the functional implications and evolutionary pressures. The study will enrich the study of potential crosstalk of miRNA-lncRNA and mRNA-ncRNA. ..
  4. Guo L, Zhao Y, Zhang H, Yang S, Chen F. Integrated evolutionary analysis of human miRNA gene clusters and families implicates evolutionary relationships. Gene. 2014;534:24-32 pubmed publisher
    ..The integrative evolutionary analysis will provide more potential evolutionary and functional relationships between homologous and clustered miRNAs. ..
  5. Guo L, Chen F. A challenge for miRNA: multiple isomiRs in miRNAomics. Gene. 2014;544:1-7 pubmed publisher
    ..This may enrich and complicate miRNA biogenesis and coding-non-coding RNA regulatory networks. ..
  6. Song L, Li D, Zeng X, Wu Y, Guo L, Zou Q. nDNA-Prot: identification of DNA-binding proteins based on unbalanced classification. BMC Bioinformatics. 2014;15:298 pubmed publisher In addition, we also predicted possible DNA-binding protein sequences in all of the sequences from the UniProtKB/Swiss-Prot database. ..