Research Topics
Genomes and GenesSpecies | Dong feng GuSummaryCountry: China Publications
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Publications
Mortality from suicide and other external cause injuries in China: a prospective cohort studyCasey M Rebholz
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1440 Canal Street, Suite 2000, New Orleans, LA 70112, USA
BMC Public Health 11:56. 2011..However, the pattern and risk factors for suicide and other external cause injuries are not well understood. This study investigates mortality from suicide and other injuries and associated risk factors in China...
Association between polymorphisms in the coagulation factor VII gene and coronary heart disease risk in different ethnicities: a meta-analysisXingbo Mo
Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
BMC Med Genet 12:107. 2011..This study was conducted to assess the associations between these polymorphisms and CHD and evaluated the associations in different ethnicities...
Heritability of blood pressure responses to dietary sodium and potassium intake in a Chinese populationDongfeng Gu
Cardiovascular Institute and Fu Wai Hospital, Beijing, China
Hypertension 50:116-22. 2007..In addition, the heritabilities of blood pressure responses to dietary sodium and potassium intake were moderate in this study population...
Body weight and mortality among men and women in ChinaDongfeng Gu
Cardiovascular Institute and Fu Wai Hospital of the Chinese Academy of Medical Sciences and Peking Union Medical College, and Chinese National Center for Cardiovascular Disease Control and Research, Beijing, China
JAMA 295:776-83. 2006..The effect of underweight and obesity on mortality has not been well characterized in Asian populations...
Prehypertension and risk of cardiovascular disease in Chinese adultsDongfeng Gu
Department of Evidence Based Medicine, Cardiovascular Institute, Fu Wai Hospital of the Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China
J Hypertens 27:721-9. 2009..To examine the excess risks associated with prehypertension and absolute benefit of treatment...
[Researches on genetics and genetic epidemiology of common complex diseases: challenge and strategies]Dong feng Gu
Department of Evidence Based Medicine and Population Genetics, Cardiovascular Institute and Fuwai Hospital, CAMS and PUMC, Beijing 100037, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 28:115-8. 2006....
[Association analysis between polymorphisms of PON gene cluster with coronary heart disease in Chinese]Xiao Ling Wang
Division of Population Genetics and Prevention, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Yi Chuan Xue Bao 32:675-81. 2005..This extensive association study has identified the PON1 -162G/A and R160G polymorphisms to be independently associated with CHD in Chinese Han population,and warrants further study to elucidate the biological mechanism...
Common SNPs of APM1 gene are not associated with hypertension or obesity in Chinese populationWei Li Yan
Division of Population Genetics and Prevention, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Biomed Environ Sci 19:179-84. 2006..To investigate whether the common variants 45T/G and 276G/T in APM1 gene were associated with hypertension combined with obesity (HO) and related clinical features in Chinese Han population...
[Polymorphisms screening of PON gene cluster]Xiao Ling Wang
Division of Population Genetics and Prevention, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Yi Chuan 27:539-43. 2005....
Variations in the calpain-10 gene are associated with the risk of type 2 diabetes and hypertension in northern Han Chinese populationShu Feng Chen
Department of Evidence Based Medicine and Division of Population Genetics, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Chin Med J (Engl) 120:2218-23. 2007..The present study aimed to identify the effects of genetic variations in the CAPN10 gene on the development of type 2 diabetes and hypertension in northern Han Chinese population...
Effect of elevated total cholesterol level and hypertension on the risk of fatal cardiovascular disease: a cohort study of Chinese steelworkersYing Yang
Department of Evidence Based Medicine, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Chin Med J (Engl) 124:3702-6. 2011..Hypertension and hypercholesterolemia co-exist more often than would be expected and whether there is a synergistic impact on fatal CVD between elevated TC and hypertension need to be further examined in Chinese population...
[Issues on association studies on complex diseases]Wei Li Yan
Division of Population Genetics and Prevention, Fu Wai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China
Yi Chuan Xue Bao 31:533-7. 2004..An optimal study design, sufficient sample size and proper controls, in conjunction of modern statistic analyses, association analyses would exert its effect on studies on susceptibility of human common diseases...
Association of the apolipoprotein B gene polymorphisms with essential hypertension in Northern Chinese Han populationWei Yan Zhao
Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Biomed Environ Sci 20:260-4. 2007..To study the association of the apolipoprotein B gene polymorphisms with essential hypertension in Northern Chinese Han population...
Paraoxonase gene cluster variations associated with coronary heart disease in Chinese Han womenShao yong Su
Division of Population Genetics, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing 100037, China
Chin Med J (Engl) 118:1167-74. 2005..The aim of the present study was to explore the role of PON gene cluster on coronary heart disease (CHD) in Chinese Han women...
[The association of single nucleotide polymorphism of slow delayed rectifier K+ channel genes with atrial fibrillation in Han nationality Chinese]Zhi Yu Zeng
Arrhythmia Center, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Zhonghua Xin Xue Guan Bing Za Zhi 33:987-91. 2005..To investigate the association between atrial fibrillation and the single nucleotide polymorphism (SNP) of slow delayed rectifier K(+) channel (I(Ks)) genes in Han nationality Chinese...
Association study of the endothelial nitric oxide synthase gene polymorphisms with essential hypertension in northern Han ChineseQi Zhao
Division of Population Genetics and Prevention, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100037, China
Chin Med J (Engl) 119:1065-71. 2006..Up to now, there has been conflicting data regarding the association between three clinically relevant polymorphisms (T-786C, intron4b/a and G894T) of the eNOS gene and essential hypertension...
The effect of total cholesterol on myocardial infarction in Chinese male hypertension populationJian Xin Li
Department of Evidence Based Medicine, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Biomed Environ Sci 23:37-41. 2010..We conducted a prospective cohort study to determine the incidence and relative risk for MI across a wide range of TC levels in Chinese male hypertension population...
[Body mass index and prognosis in patients with systolic heart failure]Yi hong Hua
Department of Cardiology, Heart Failure Care Unit, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Zhonghua Xin Xue Guan Bing Za Zhi 37:870-4. 2009..However, in patients with certain chronic diseases, including heart failure, low BMI has been associated with increased mortality. We investigated the association between BMI and prognosis in patients with systolic HF...
Relationship between cystathionine gamma-lyase gene polymorphism and essential hypertension in Northern Chinese Han populationYun Li
Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Chin Med J (Engl) 121:716-20. 2008..Up to now, the reports on the relationship between the polymorphisms of cystathionine gamma-lyase gene (CTH) and essential hypertension (EH) are limited. This study was designed to assess their underlying relationship...
Influence of fibrinogen beta-chain gene variations on risk of myocardial infarction in a Chinese Han populationXiang feng Lu
Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Chin Med J (Engl) 121:1549-53. 2008..This study was conducted to elucidate the association between the genetic polymorphisms of the fibrinogen beta-chain (FGB) gene and MI in Chinese Han population...
[Major causes of death among male steelworkers in Beijing: a prospective study]Xiu fang Duan
Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Zhonghua Xin Xue Guan Bing Za Zhi 34:651-4. 2006..To evaluate the major causes of death and risk factors among male steelworkers in Beijing...
[Two approaches of quantitative-trait linkage analysis]Shao yong Su
Division of Population Genetics and Prevention, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100 037, China
Yi Chuan 26:253-6. 2004..We have outlined the model assumption, the algorithm and the extensions for the both methods...
[The analysis of drug cost and direct medical expense in community health management of hypertensive patients]Xiao Hua Liang
State Key Laboratory of Translational Cardiovascular Medicine, Fuwai Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100037, China
Zhonghua Yu Fang Yi Xue Za Zhi 45:732-6. 2011....
[Electrocardiogram analysis in high risk population of unexplained sudden death in Yunnan province]Li Feng
Cardiac Arrhythmia Center, Fu Wai Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China
Zhonghua Xin Xue Guan Bing Za Zhi 35:1155-8. 2007..The purpose of this study was to analyze the electrocardiographic features of the people living in the area with high incidence of unexplained sudden deaths in Yunnan province...
[Association between single nucleotide polymorphisms of matrix metalloproteinase-3 gene and the severity of coronary atherosclerosis in patients with coronary artery disease]Na qiong Wu
Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Zhonghua Xin Xue Guan Bing Za Zhi 36:501-5. 2008..To investigate the association between the severity of coronary arteries in patients with coronary artery disease and the single nucleotide polymorphisms of MMP-3 gene...
Modulation of KCNQ1 current by atrial fibrillation-associated KCNE4 (145E/D) gene polymorphismKe juan Ma
Center for Arrhythmia Diagnosis and Treatment, Fuwai Cardiovascular Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100037, China
Chin Med J (Engl) 120:150-4. 2007..However, the functional effect of the KCNE4 145E/D polymorphism is still unknown...
[A 20-year prospective study on risk factors for myocardial infarction of 5,137 men in Capital Steel and Iron Company]Han Yue
Cardiovascular Institute of Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Zhonghua Yu Fang Yi Xue Za Zhi 38:43-6. 2004..It is clear and rational that intervention and modification of those traditional risk factors can lead to a decrease in coronary events in Chinese population...
[An evaluation on effectiveness of worksite-based intervention for cardiovascular disease during 1974 - 1998 in capital iron and steel company of Beijing]Xi-Gui Wu
Division of Population Genetics and Prevention, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Zhonghua Yu Fang Yi Xue Za Zhi 37:93-7. 2003..CONCLUSION: Worksite-based comprehensive intervention for CVD prevention and control was feasible and cost-effective in decreasing risk factors for CVD, incidence and mortality rate of stroke in population of urban areas of China...
[Progress in the studies on the relationship between the polymorphism of P22phox gene and coronary heart disease]Jian-gong Zhao
Division of Population Genetics and Prevention, Fuwai Cardiovascular Institute, CAMS, PUMC, Beijing 100037, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 24:105-8, 104. 2002..To distinguish the relationship between them will be beneficial to elucidate the genetic mechanisms of CHD, and develop a new genetic marker to provide theoretical base for the prevention and cure of CHD...
[Assessment and analysis on the risk and community treatment of hypertension in rural areas in Changshu city]Min-gao Xu
Changshu Center for Disease Prevention and Control, Changshu 215500, China
Zhonghua Liu Xing Bing Xue Za Zhi 25:33-5. 2004..It is necessary to strengthen a comprehensive intervention program for hypertension control...
Linkage analysis of chromosome 14 and essential hypertension in Chinese populationWei-yan Zhao
Division of Population Genetics and Prevention, Cardiovascular Institute, Fuwai Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China
Chin Med J (Engl) 118:1939-44. 2005..CONCLUSION: There was no substantial evidence to support the linkage of chromosome 14 and essential hypertension or blood pressure trait in Chinese hypertensive subjects in this study...
[Pulse pressure and prevalence of stroke and myocardial infarction in Chinese population]Xiu-Fang Duan
Department of Population Genetics and Prevention, Fuwai Hospital and Cardiovascular Disease Institute of Chinese Academy of Medical Sciences, Beijing 100037, China
Zhonghua Yu Fang Yi Xue Za Zhi 38:265-8. 2004..CONCLUSIONS: Prevalence of stroke and MI increased with the breadth of PP and age. Broader PP may be an important and independent predictor of risks of stroke and MI, especially in the aged people...
[Current status and prospects of the prevention and control of cardiovascular diseases]Dong-feng Gu
Division of Population Genetics and Prevention, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Zhonghua Yu Fang Yi Xue Za Zhi 37:75-6. 2003
[Prevalence of isolated systolic hypertension in Chinese adult population]Jian-feng Huang
Department of Population Genetics and Prevention, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Zhonghua Yu Fang Yi Xue Za Zhi 39:7-10. 2005..CONCLUSION: There existed a higher prevalence of systolic hypertension in China, to which enough attention should be paid...
[A study on the risk factors of cardiovascular between hypertensive patients and normal subjects in the same family]Qi Hua
Department of Cardiovascular, Xuan Wu Hospital, Capital University of Medical Sciences, Beijing 100053, China
Zhonghua Liu Xing Bing Xue Za Zhi 26:44-6. 2005..CONCLUSION: It is important that either persons with normal blood pressure or hypertension should control their body weights (BMI) since the rate of metabolic syndrome in hypertension group was high...
[Prevalence, awareness, treatment and control of hypertension in Chinese adults]Dong-feng Gu
Division of Population Genetics and Prevention, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Zhonghua Yu Fang Yi Xue Za Zhi 37:84-9. 2003..It is urgently needed to improve prevention, detection and treatment for hypertension in adults...
