Yan LiSummaryAffiliation: Fujian Province Country: China Publications
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[Effects of magnesium deficiency on senescence of Dimocarpus longana leaves]Yan Li
Fujian Agricultural and Forestry University, Fuzhou 350002
Ying Yong Sheng Tai Xue Bao 13:311-4. 2002..Whereas the content of H2O2, the rate of O2-. generation as well as the content of malondialdehyde (MDA) increased. The results suggested that magnesium deficiency had significant effect on the senescence of Dimocarpus longana leaves...- Endogenous TNFalpha lowers maximum peak bone mass and inhibits osteoblastic Smad activation through NF-kappaBYan Li
Division of Endocrinology and Metabolism and Lipids, Emory University School of Medicine, Atlanta, Georgia 30322, USA
J Bone Miner Res 22:646-55. 2007..In vitro, TNFalpha suppresses BMP-2- and TGFbeta-mediated Smad activation through induction of NF-kappaB. Consistently, pharmacological suppression of NF-kappaB augments osteoblast differentiation and mineralization in vitro... 
Effects of manganese-excess on CO2 assimilation, ribulose-1,5-bisphosphate carboxylase/oxygenase, carbohydrates and photosynthetic electron transport of leaves, and antioxidant systems of leaves and roots in Citrus grandis seedlingsQing Li
Institute of Horticultural Plant Physiology, Biochemistry and Molecular Biology, Fujian Agriculture and Forestry University, Fuzhou, China
BMC Plant Biol 10:42. 2010..The objective of this study were to understand the mechanisms by which Mn-excess leads to a decrease in CO2 assimilation and to test the hypothesis that Mn-induced changes in antioxidant systems differ between roots and leaves...- Reactive oxygen species, but not mitochondrial membrane potential, is associated with radiation-induced apoptosis of AHH-1 human lymphoblastoid cellsZi Bing Wang
Department of Immunology, Beijing Institute of Radiation Medicine, 27 Taiping Road, Beijing 100850, P R China
Cell Biol Int 31:1353-8. 2007..Moreover, the results might cast doubts on those studies using Rhodamine 123 which hypothesized that the fall in MMP is one of the early events of apoptosis... - Cardiovascular protection of nonmitogenic human acidic fibroblast growth factor from oxidative damage in vitro and in vivoXiao Kun Li
Research Institute for Diabetic Complications, School of Pharmaceutical Sciences, Wenzhou Medical College, Wenzhou, PR China
Cardiovasc Pathol 16:85-91. 2007.... - [Effects of rosiglitazone on the expression connective tissue growth factor in tubulointerstitium in KKA(y) mice]Yan Qin
Department of Nephrology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 28:817-21. 2006..05). CONCLUSION: Heterogeneous rosiglitazone may upregulate the expression of PPARgamma in renal cortex, and remarkably inhibit the expressions of CTGF in the tubulointerstitium and renal cortex in diabetic KKA(y) mice... - Chronic distress, age-related neuropathology, and late-life dementiaRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, 600 South Paulina, Suite 1038, Chicago, IL 60612, USA
Psychosom Med 69:47-53. 2007..The objective of this study was to test whether common age-related neuropathology could account for the relation of chronic distress to dementia... - Cognitive decline in old age: separating retest effects from the effects of growing olderRobert S Wilson
Rush Alzheimer s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA
Psychol Aging 21:774-89. 2006..Individual differences in retest effects were substantial but not consistent across cognitive measures. The results suggest that retest-based improvement in cognitive test performance can be substantial and persistent... - The rat Apg3p/Aut1p homolog is upregulated by ischemic preconditioning in the retinaBill X Wu
Department of Ophthalmology, Medical University of South Carolina, Charleston, SC, USA
Mol Vis 12:1292-302. 2006..In this study, we have identified and characterized the rat homolog of yeast Apg3p/Aut1p, an important autophagy protein encoded by the autophagy 3-like (APG3L) gene. We have also further characterized the homologous human APG3L gene... - Estimation of the mediation effect with a binary mediatorYan Li
Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL 60612, USA
Stat Med 26:3398-414. 2007.... - [Anti-CD28 antibody costimulation enhances anti-CD3 antibody activating T cells and lowering TGF-beta expression in vitro]Qun Lou
Department of Blood Transfusion, The General Hospital of PLA, Beijing 100853, China
Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:547-51. 2006..It was concluded that the anti-CD28 antibody costimulation could provide stimulatory signal II, which make T cells more active, while the expression of TGF-beta significantly down-regulated... - Substantia nigra tangles are related to gait impairment in older personsJulie A Schneider
Rush Alzheimer s Disease Center, Rush University Medical Center, 600 S Paulina Street, Chicago, IL, USA
Ann Neurol 59:166-73. 2006..Our objective was to test the hypothesis that substantia nigra neurofibrillary tangles (NFTs) are related to parkinsonian signs in older persons with and without dementia... - Ecophysiological response and morphological adjustment of two Central Asian desert shrubs towards variation in summer precipitationHao Xu
Fukang Station of Desert Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, 40 3 South Beijing Road, 830011 Urumqi, Xinjiang, China
Plant Cell Environ 30:399-409. 2007..On account of its positive responses to increased precipitation, H. ammodendron is predicted to succeed in interspecific competition in a future, moister habitat... - Protection against myocardial ischemia/reperfusion injury in TLR4-deficient mice is mediated through a phosphoinositide 3-kinase-dependent mechanismFang Hua
Department of Surgery, East Tennessee State University, Johnson City, TN 37614, USA
J Immunol 178:7317-24. 2007..These data also suggest that modulation of TLR4/PI3K/Akt-dependent signaling pathways may be a viable strategy for reducing myocardial I/R injury... - Antitumor effect and mechanism of Gecko on human esophageal carcinoma cell lines in vitro and xenografted sarcoma 180 in Kunming miceFei Liu
Medical College, Henan University of Science and Technology, Anhui Road 6, Luoyang 471003, Henan Province, China
World J Gastroenterol 14:3990-6. 2008..To investigate the anti-tumor effect of Chinese medicine Gecko on human esophageal carcinoma cell lines and xenografted sarcoma 180 in Kunming mice and its mechanism... - Expression of GLUT-1 in psoriasis and the relationship between GLUT-1 upregulation induced by hypoxia and proliferation of keratinocyte growthJuan Tao
J Dermatol Sci 51:203-7. 2008 
Roles of reactive oxygen species and MAP kinases in the primary rat hepatocytes death induced by toosendaninYunhai Zhang
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China
Toxicology 249:62-8. 2008..These results suggested that toosendanin causes death of primary rat hepatocytes by mitochondrial dysfunction and caspase activation. Generation of ROS and MAP kinases activation might be involved in this process...- The inhibitory effect of p75 neurotrophin receptor on growth of human hepatocellular carcinoma cellsHe Yuanlong
State Key Laboratory of Cancer Biology and Institute of Digestive Diseases, Xijing Hospital, The Fourth Military Medical University, 17 Changle Western Road, Xi an, Shaanxi Province 710032, PR China
Cancer Lett 268:110-9. 2008..Therefore, we provided the evidence that p75NTR was a potential tumor suppressor and might be used as a therapeutic target for hepatocellular carcinoma... - GAD-IgG-inducing CD4+Foxp3+Treg cells suppressing diabetes are involved in the increasing ratio of CD80+:CD86+ CELLS in NOD miceRenxi Wang
Department of Molecular Immunology, Institute of Basic Medical Sciences, Beijing, PR China
Arch Med Res 39:299-305. 2008..However, the underlying mechanisms by which CD4(+)Foxp3(+)Treg cells suppress diabetes remain unclear... - Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stressViviana I Perez
The Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, 15355 Lambda Drive, San Antonio, TX 78229, USA
Free Radic Biol Med 44:882-92. 2008..Our results suggest that Txn2 plays an important role in protecting the mitochondria against oxidative stress and in sensitizing the cells to ROS-induced apoptosis... - (-)Gossypol and its combination with imatinib induce apoptosis in human chronic myeloid leukemic cellsYang Meng
Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Leuk Lymphoma 48:2204-12. 2007..These results suggest that (-)gossypol induced apoptosis in K562 cells through a mitochondria pathway and that the combination of imatinib and (-)gossypol might be an effective treatment for CML... - Two calcium-dependent protein kinases, CPK4 and CPK11, regulate abscisic acid signal transduction in ArabidopsisSai Yong Zhu
China State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, 100094 Beijing, China
Plant Cell 19:3019-36. 2007.... - Inhibition of oxidative-stress-induced platelet aggregation by androgen at physiological levels via its receptor is associated with the reduction of thromboxane A2 release from plateletsShijun Li
Division of Geriatric Cardiology, Chinese PLA General Hospital at No 28, FuXing Road, Beijing 100853, PR China
Steroids 72:875-80. 2007..The purposes of our study are to assess the effect of androgen at physiological concentration via its receptor on oxidative-stress-induced platelet aggregation and to further elucidate the possible mechanism... - Association of manganese superoxide dismutase expression with progression of carcinogenesis in Barrett esophagusBruce Hermann
Department of Surgery, Division of Surgical Oncology, University of Louisville School of Medicine, Louisville, KY 40202, USA
Arch Surg 140:1204-9; discussion 1209. 2005..Further evaluation within genotypic expression and the role of antioxidants is needed in the effective screening and treatment of BE... - Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-cateninQingqing Ding
Department of Molecular and Cellular Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Mol Cell 19:159-70. 2005.... - Responses of ABA and CTK to soil drought in leafless and leafy apple treeYan Li
Department of Horticulture, Zhejiang University, Hangzhou 310029, China
J Zhejiang Univ Sci 4:101-8. 2003..Total CTK showed no reduction in the earlier drought stage and decreased in the later drought stage... - A novel erythroid differentiation related gene EDRF1 upregulating globin gene expression in HEL cellsDuncheng Wang
Institute of Basic Medical Sciences, Academy of Military Medical Sciences, Beijing 100850, China
Chin Med J (Engl) 115:1701-5. 2002..To further characterize the differentiation inducing properties of EDRF1 and demonstrate its functional pathway involved in regulation of globin gene expression... - [Microscopy identification of Phyllanthus simplex]Xiaofeng Niu
Pharmacy College, Xi'an Jiaotong University, Xi'an 710061
Zhong Yao Cai 25:397-9. 2002..Paracytic type stomata are visible. CONCLUSION: Above-mentioned characters can be used for the identification of Phyllanthus simplex... - [The protective effect of bicyclol on ischemia-reperfusion induced kidney injury in rats]Dong-mei Zhao
Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China
Yao Xue Xue Bao 37:412-4. 2002..CONCLUSION: The protective action of bicyclol on kidney injury induced by ischemia-reperfusion may be attributed to its induction of kidney GSH and the GST, stabilization on mitochondria membrane and the inhibition on lipid peroxidation... - [Study on the biological activity and molecular mechanism of IFNalpha on human myeloma cell line Sko-007]Lun Song
Institute of Basic Medical Science, Academy of Military Medical Science, Beijing 100850, China
Zhonghua Xue Ye Xue Za Zhi 23:517-9. 2002..CONCLUSION: The inhibitory effect of IFNalpha on the proliferation of Sko-007 cells was mediated by gp130 down-regulation, degradation of Bcl-2 family anti-apoptotic proteins and inhibition of ERK activation... - IL-6 inhibits apoptosis of human myeloma cell line XG-7 through activation of JAK/STAT pathway and up-regulation of Mcl-1Lun Song
Institute of Basic Medical Sciences, Academy of Military Medical Sciences, Beijing 100850, P R China
Ai Zheng 21:113-6. 2002.... - Developmental changes in short-term synaptic depression in the neonatal mouse spinal cordYan Li
Laboratory of Neural Control, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892-4455, USA
J Neurophysiol 88:3218-31. 2002..The time constants of resource renewal showed surprisingly little change through the first 12 days of postnatal life... - beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancerJiong Deng
Department of Molecular and Cellular Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Cancer Cell 2:323-34. 2002..Thus, beta-catenin may play an important role in oncogenesis through the crossregulation of NF-kappa B... - Annonaceous acetogenins from the leaves of Annona montanaLi-Quan Wang
Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Toyama 930-0194, Japan
Bioorg Med Chem 10:561-5. 2002..Furthermore, the previously isolated cytotoxic acetogenin annonacin against LLC was examined for in vivo antitumor activity with LLC tumor cells... - [Microscopy identification of Caltha palustris L. var. membranacea Turcz.]Xiaofeng Niu
Pharmacy College, Xi'an Jiaotong University, Xi'an 710061
Zhong Yao Cai 26:171-2. 2003..var. membrancea Turcz.. Anomocytic type stomata are visible. CONCLUSION: Above mentioned characters can be used for the identification of Caltha palustris L. var. membranacea Turcz... - Chromatin reorganization accompanying cellular dedifferentiation is associated with modifications of histone H3, redistribution of HP1, and activation of E2F-target genesLeor Williams
Department of Plant Sciences, The Weizmann Institute of Science, Rehovot, Israel
Dev Dyn 228:113-20. 2003..We propose that chromatin reorganization is central for reversion of the differentiation process leading to resetting of the gene expression program and activation of silent genes... - Maspin expression and its clinicopathological significance in tumorigenesis and progression of gastric cancerMeng chun Wang
Department of Gastroenterology, The Second Affiliated Hospital of China Medical University, Shenyang 110004, Liaoning Province, China
World J Gastroenterol 10:634-7. 2004..To investigate maspin expression in tumorigenesis and progression of gastric cancer and to explore its relevant molecular mechanisms... - Effects of nitric oxide donors on cybrids harbouring the mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) A3243G mitochondrial DNA mutationJagdeep K Sandhu
Neurogenesis and Brain Repair Group, M54, Institute for Biological Sciences, National Research Council Canada, 1200 Montreal Road, Ottawa, ON, Canada K1A 0R6
Biochem J 391:191-202. 2005..The vulnerability of the cybrids to these types of injury correlated with the cellular energy status, which were compromised by the MELAS mutation... - Taurine inhibits ischemia/reperfusion-induced compartment syndrome in rabbitsJi-Xian Wang
Institute of Cardiovascular Disease Research, The First Hospital of Peking University, Beijing 100034, China
Acta Pharmacol Sin 26:821-7. 2005.... - Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factorYan Li
Institute of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
Nature 434:894-8. 2005..Thus, TRPC channel activity is essential for nerve-growth-cone guidance by BDNF... - Effect of three resistant soybean genotypes on the fecundity, mortality, and maturation of soybean aphid (Homoptera: Aphididae)Yan Li
Department of Crop Sciences, National Soybean Research Center, University of Illinois, Urbana, IL 61801, USA
J Econ Entomol 97:1106-11. 2004..Reduced feeding due to ingestion of potentially toxic compounds in soybean may explain the possible mechanism of resistance to the soybean aphid... - Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiationRalph Brandenberger
Geron Corporation, Menlo Park, California 94025, USA
Nat Biotechnol 22:707-16. 2004..The genomic data presented here may facilitate the derivation of clinically useful cell types from hES cells... - Equine estrogen metabolite 4-hydroxyequilenin induces anchorage-independent growth of human mammary epithelial MCF-10A cells: differential gene expressionMuriel Cuendet
Department of Medicinal Chemistry and Pharmacognosy M C 781, College of Pharmacy, University of Illinois at Chicago, 833 S Wood Street, Chicago, IL 60612, USA
Mutat Res 550:109-21. 2004..Moreover, we showed the involvement of other genes important in cell transformation and oxidative stress, strengthening the hypothesis that this mechanism plays a considerable role in 4-OHEN-induced anchorage-independent growth... - [Effects of oxidized low-density lipoprotein on expression of type A scavenger receptor in human mesangial cells]Wen-ling Ye
Department of Nephrology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 26:34-7. 2004..However, LDL had no effect on the expression of SR-A. CONCLUSIONS: It suggests that SR-A be a major binding receptor to uptake Ox-LDL in HMC. Ox-LDL may promote the progression of chronic renal diseases through up-regulation of SR-A... - Attenuation of free radical production and paracrystalline inclusions by creatine supplementation in a patient with a novel cytochrome b mutationMark A Tarnopolsky
Department of Medicine, McMaster University Medical Center, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
Muscle Nerve 29:537-47. 2004..The results suggest that the development of exercise-induced paracrystalline inclusions may be influenced by the G15497A mtDNA mutation, and that CM mitigates against the pathological consequences of this mutation... - In utero exposure to tobacco and alcohol modifies neurobehavioral development in mice offspring: consideration a role of oxidative stressYan Li
Department of Pharmacology, Medical College of Wuhan University, 430071, China
Pharmacol Res 49:467-73. 2004..CONCLUSION: Our study shows the long-term neurotoxicity associated with prenatal tobacco and alcohol exposure, and suggests that the deleterious outcome may be in relation to increased free radicals formation and oxidative stress... - Down-regulation of vascular endothelial growth factor and up-regulation of pigment epithelium-derived factor: a possible mechanism for the anti-angiogenic activity of plasminogen kringle 5Guoquan Gao
Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina 29403, USA
J Biol Chem 277:9492-7. 2002....