Huanzhang Zhu

Summary

Affiliation: Fudan University
Country: China

Publications

  1. ncbi request reprint Histone deacetylase inhibitor MC1293 induces latent HIV-1 reactivation by histone modification in vitro latency cell lines
    Xiying Qu
    State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai 200433, P R China
    Curr HIV Res 11:24-9. 2013
  2. ncbi request reprint Transgenic mice expressing hepatitis B virus X protein are more susceptible to carcinogen induced hepatocarcinogenesis
    Huanzhang Zhu
    State Key Laboratory of Genetic Engineering, Institute of Genetic, School of Life Sciences, Fudan University, Shanghai 200433, China
    Exp Mol Pathol 76:44-50. 2004
  3. doi request reprint Involvement of histone methyltransferase GLP in HIV-1 latency through catalysis of H3K9 dimethylation
    Donglin Ding
    State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai 200433, China
    Virology 440:182-9. 2013
  4. pmc Selective histonedeacetylase inhibitor M344 intervenes in HIV-1 latency through increasing histone acetylation and activation of NF-kappaB
    Hao Ying
    State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, China
    PLoS ONE 7:e48832. 2012
  5. doi request reprint HIV-1 reactivation induced by apicidin involves histone modification in latently infected cells
    Shiguan Lin
    State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, China
    Curr HIV Res 9:202-8. 2011
  6. ncbi request reprint Association between polymorphism of SDF1 (CXCL12) gene and HIV-1 susceptibility: a meta-analysis
    Sijie Liu
    The State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Science, Fudan University, Shanghai 200433, China
    Curr HIV Res 9:112-9. 2011
  7. pmc Effect of CCR5-Δ32 heterozygosity on HIV-1 susceptibility: a meta-analysis
    Sijie Liu
    The State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Science, Fudan University, Shanghai, China
    PLoS ONE 7:e35020. 2012

Collaborators

  • Yun Wang
  • Lin Li
  • Sijie Liu
  • Hao Ying
  • Xiying Qu
  • Xin Zhou
  • Pengfei Wang
  • Chuijin Kong
  • Shiguan Lin
  • Xiaohui Wang
  • Donglin Ding
  • Yuhao Zhang
  • Shaohui Liu
  • Lin Liu
  • Daru Lu
  • Jie Wu

Detail Information

Publications7

  1. ncbi request reprint Histone deacetylase inhibitor MC1293 induces latent HIV-1 reactivation by histone modification in vitro latency cell lines
    Xiying Qu
    State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai 200433, P R China
    Curr HIV Res 11:24-9. 2013
    ..The results suggest that the acetylation of histone plays an important role in regulating HIV-1 LTR gene expression, and MC1293 is potential drug candidate for antilatency therapies...
  2. ncbi request reprint Transgenic mice expressing hepatitis B virus X protein are more susceptible to carcinogen induced hepatocarcinogenesis
    Huanzhang Zhu
    State Key Laboratory of Genetic Engineering, Institute of Genetic, School of Life Sciences, Fudan University, Shanghai 200433, China
    Exp Mol Pathol 76:44-50. 2004
    ..Taken together, our results suggest that HBx gene expression alone is not sufficient for carcinogenesis, but may act as a promoter for malignant transformation...
  3. doi request reprint Involvement of histone methyltransferase GLP in HIV-1 latency through catalysis of H3K9 dimethylation
    Donglin Ding
    State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai 200433, China
    Virology 440:182-9. 2013
    ..GLP knockdown by small interfering RNA clearly induced HIV-1 LTR expression. Results suggest that GLP may play a significant role in the maintenance of HIV-1 latency by catalyzing dimethylation of H3K9...
  4. pmc Selective histonedeacetylase inhibitor M344 intervenes in HIV-1 latency through increasing histone acetylation and activation of NF-kappaB
    Hao Ying
    State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, China
    PLoS ONE 7:e48832. 2012
    ..However, little is known about the effects and action mechanism of M344 in inducing HIV expression in latently infected cells...
  5. doi request reprint HIV-1 reactivation induced by apicidin involves histone modification in latently infected cells
    Shiguan Lin
    State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, China
    Curr HIV Res 9:202-8. 2011
    ..Our research reveals a potent activator for reactivating latent HIV-1 and shows promise for HIV-1 therapy...
  6. ncbi request reprint Association between polymorphism of SDF1 (CXCL12) gene and HIV-1 susceptibility: a meta-analysis
    Sijie Liu
    The State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Science, Fudan University, Shanghai 200433, China
    Curr HIV Res 9:112-9. 2011
    ..In conclusion, no statistically significant association between SDF1 genotype and HIV-1 susceptibility was detected in any models. Our data suggested that SDF1 genotype might have limited effect on HIV-1 susceptibility...
  7. pmc Effect of CCR5-Δ32 heterozygosity on HIV-1 susceptibility: a meta-analysis
    Sijie Liu
    The State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Science, Fudan University, Shanghai, China
    PLoS ONE 7:e35020. 2012
    ..However, no definite results have been put forward about whether heterozygosity for a 32-basepair deletion in CCR5 gene (CCR5-Δ32) can affect HIV-1 susceptibility...