G Zhou

Summary

Affiliation: Fudan University
Country: China

Publications

  1. pmc Combination of SLC administration and Tregs depletion is an attractive strategy for targeting hepatocellular carcinoma
    Long Chen
    Principle Investigator of the Lab of Tumor Immunology, the Department of Anatomy and Histology and Embryology, Shanghai Medical College, Fudan University, 138 Yixueyuan Road, Shanghai 200032, P R China
    Mol Cancer 12:153. 2013
  2. ncbi request reprint Computer aided quantification for retinal lesions in patients with moderate and severe non-proliferative diabetic retinopathy: a retrospective cohort study
    Huiqun Wu
    Department of Medical Informatics, Medical School of Nantong University, Nantong 226001, China
    BMC Ophthalmol 14:126. 2014
  3. pmc Special role of Foxp3 for the specifically altered microRNAs in Regulatory T cells of HCC patients
    Long Chen
    Lab of Tumor Immunology, Department of Anatomy and Histology and Embryology, Shanghai Medical College of Fudan University, 138 Yixueyuan Road, 200032 Shanghai, PR China
    BMC Cancer 14:489. 2014
  4. ncbi request reprint Modulation of retinal cell populations and eye size in retinoic acid receptor knockout mice
    G Zhou
    Center for Neuroscience, University of Tennessee, Memphis, TN 38163, USA
    Mol Vis 7:253-60. 2001
  5. ncbi request reprint Eye1 and Eye2: gene loci that modulate eye size, lens weight, and retinal area in the mouse
    G Zhou
    Center for Neuroscience and the Department of Anatomy and Neurobiology, University of Tennessee, Memphis 38163, USA
    Invest Ophthalmol Vis Sci 40:817-25. 1999
  6. ncbi request reprint Genetic dissection of retinal development
    R W Williams
    Department of Anatomy and Neurobiology and the Center for Neuroscience, University of Tennessee, 855 Monroe Avenune, Memphis, TN 38163, USA
    Semin Cell Dev Biol 9:249-55. 1998
  7. ncbi request reprint Miniaturized pyrosequencer for DNA analysis with capillaries to deliver deoxynucleotides
    G Zhou
    Hitachi, Ltd, Central Research Laboratory, Tokyo, Japan
    Electrophoresis 22:3497-504. 2001
  8. ncbi request reprint [Isolation of high-quality genomic DNA from plants]
    Z Y Luo
    Molecular Biology Research Center, Xiangya Medical College, Central South University, Changsha 410078, China
    Hunan Yi Ke Da Xue Xue Bao 26:178-80. 2001
  9. ncbi request reprint Single nucleotide polymorphisms and haplotypes of histamine N-methyltransferase in patients with gastric ulcer
    G L Chen
    Pharmacogenetics Research Institute, Institute of Clinical Pharmacology, Central South University, 410078 Changsha, Hunan, P R China
    Inflamm Res 53:484-8. 2004
  10. ncbi request reprint A Chinese isolate of barley yellow dwarf virus-PAV represents a third distinct species within the PAV serotype
    F Liu
    State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, PR China
    Arch Virol 152:1365-73. 2007

Collaborators

Detail Information

Publications20

  1. pmc Combination of SLC administration and Tregs depletion is an attractive strategy for targeting hepatocellular carcinoma
    Long Chen
    Principle Investigator of the Lab of Tumor Immunology, the Department of Anatomy and Histology and Embryology, Shanghai Medical College, Fudan University, 138 Yixueyuan Road, Shanghai 200032, P R China
    Mol Cancer 12:153. 2013
    ..We hypothesized that the intratumoral injections of SLC and depletion of Tregs would have stronger inhibition effects on the progression of hepatocellular carcinoma (HCC) in mice...
  2. ncbi request reprint Computer aided quantification for retinal lesions in patients with moderate and severe non-proliferative diabetic retinopathy: a retrospective cohort study
    Huiqun Wu
    Department of Medical Informatics, Medical School of Nantong University, Nantong 226001, China
    BMC Ophthalmol 14:126. 2014
    ..The traditional subjective judgments by clinicians are dependent on their experience and can be subject to lack of consistency and therefore a quantification method is worthwhile...
  3. pmc Special role of Foxp3 for the specifically altered microRNAs in Regulatory T cells of HCC patients
    Long Chen
    Lab of Tumor Immunology, Department of Anatomy and Histology and Embryology, Shanghai Medical College of Fudan University, 138 Yixueyuan Road, 200032 Shanghai, PR China
    BMC Cancer 14:489. 2014
    ..The microRNAs (miRNAs) are identified as the key modulators in Tregs. This study was to explore whether the expression profiles of miRNAs of Tregs were different in HCC-activated Tregs and whether Foxp3 had special effects on them...
  4. ncbi request reprint Modulation of retinal cell populations and eye size in retinoic acid receptor knockout mice
    G Zhou
    Center for Neuroscience, University of Tennessee, Memphis, TN 38163, USA
    Mol Vis 7:253-60. 2001
    ..Rara is of particular interest because this gene is a candidate for Nnc1, a QTL that controls retinal ganglion cell proliferation...
  5. ncbi request reprint Eye1 and Eye2: gene loci that modulate eye size, lens weight, and retinal area in the mouse
    G Zhou
    Center for Neuroscience and the Department of Anatomy and Neurobiology, University of Tennessee, Memphis 38163, USA
    Invest Ophthalmol Vis Sci 40:817-25. 1999
    ..The genetic basis of variation in eye size in mice was explored, and genes that modulate eye weight, lens weight, and retinal area were mapped...
  6. ncbi request reprint Genetic dissection of retinal development
    R W Williams
    Department of Anatomy and Neurobiology and the Center for Neuroscience, University of Tennessee, 855 Monroe Avenune, Memphis, TN 38163, USA
    Semin Cell Dev Biol 9:249-55. 1998
    ..Here we review this approach and give three specific examples of how genes with well-defined functions in retinal development are being mapped and characterized...
  7. ncbi request reprint Miniaturized pyrosequencer for DNA analysis with capillaries to deliver deoxynucleotides
    G Zhou
    Hitachi, Ltd, Central Research Laboratory, Tokyo, Japan
    Electrophoresis 22:3497-504. 2001
    ..The new system is successfully applied to sequence a GC rich region or a region close to a priming region where misreading frequently occurs. A rapid analysis for a short DNA was easily achieved with this small instrument...
  8. ncbi request reprint [Isolation of high-quality genomic DNA from plants]
    Z Y Luo
    Molecular Biology Research Center, Xiangya Medical College, Central South University, Changsha 410078, China
    Hunan Yi Ke Da Xue Xue Bao 26:178-80. 2001
    ..We expect that this method can also be applied to other plants...
  9. ncbi request reprint Single nucleotide polymorphisms and haplotypes of histamine N-methyltransferase in patients with gastric ulcer
    G L Chen
    Pharmacogenetics Research Institute, Institute of Clinical Pharmacology, Central South University, 410078 Changsha, Hunan, P R China
    Inflamm Res 53:484-8. 2004
    ..Histamine N-methyltransferase (HNMT) is the major metabolizing enzyme for histamine inactivation in human stomach...
  10. ncbi request reprint A Chinese isolate of barley yellow dwarf virus-PAV represents a third distinct species within the PAV serotype
    F Liu
    State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, PR China
    Arch Virol 152:1365-73. 2007
    ..These data suggest that PAV-CN may have undergone a recombination event with GAV and that PAV-CN represents a third distinct species within the PAV serotype of BYDV...
  11. ncbi request reprint Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate
    X Gan
    Department of Atherosclerosis and Endocrinology, Merck Research Laboratories, Rahway, New Jersey 07065, USA
    J Biol Chem 276:48702-8. 2001
    ..These data indicate that activation of the Rho proteins may change the activation status of LXR...
  12. ncbi request reprint The pattern of gene expression in mouse Gr-1(+) myeloid progenitor cells
    J Chen
    Department of Medicine, University of Chicago, 5841 S. Maryland, MC2115, Chicago, Illinois 60637, USA
    Genomics 77:149-62. 2001
    ..Our data provide a basis for studying altered gene expression in myeloid disorders using mouse models...
  13. pmc Quantitative detection of single nucleotide polymorphisms for a pooled sample by a bioluminometric assay coupled with modified primer extension reactions (BAMPER)
    G Zhou
    Hitachi Ltd, Central Research Laboratory, 1-280 Higashi-Koigakubo, Kokubunji-shi, Tokyo 185-8601, Japan
    Nucleic Acids Res 29:E93. 2001
    ..The method is sensitive enough to detect 14 amol ssM13 DNA. The proposed method seems very promising in terms of realizing a cost-effective, large-scale human genetic testing system...
  14. ncbi request reprint Generation of high-quantity and quality tag/ditag cDNAs for SAGE analysis
    S Lee
    University of Chicago Medical Center, 5841 S. Maryland MC2115, Chicago, IL 60637, USA
    Biotechniques 31:348-50, 352-4. 2001
    ..These modifications provide a large quantity of initial 3' cDNAs and high-quality tags and ditags for the construction of SAGE libraries...
  15. ncbi request reprint 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells
    X Fu
    Department of Atherosclerosis and Endocrinology, and Metabolic Research, Merck Research Laboratories, Rahway, New Jersey 07065, USA
    J Biol Chem 276:38378-87. 2001
    ..We conclude that 27-hydroxylation of cholesterol is an important pathway for LXR activation in response to cholesterol overload...
  16. ncbi request reprint Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha. PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor expresso
    J W Lawrence
    Department of Safety Assessment, Merck Research Laboratories, Merck and Co, Inc, West Point, Pennsylvania 19486, USA
    J Biol Chem 276:31521-7. 2001
    ..These results suggest that other factors besides PPAR alpha levels determine the species-specific response of human and rat hepatocytes to the induction of PP...
  17. ncbi request reprint Partial cloning and sequencing of chick fibrillin-1 cDNA
    G Zhou
    Munroe Center for Human Genetics, University of Nebraska Medical Center, Omaha 68198 5430, USA
    In Vitro Cell Dev Biol Anim 36:19-25. 2000
    ..Antisense and sense riboprobes were synthesized and used in in situ hybridization in stage 14 chick embryos and high levels of FBN1 transcripts were observed in the heart...
  18. pmc The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development
    F A Pereira
    Department of Cell Biology, Baylor College of Medicine, Houston, Texas 77030 USA
    Genes Dev 13:1037-49. 1999
    ..This down-regulation suggests that COUP-TFII may be required for bidirectional signaling between the endothelial and mesenchymal compartments essential for proper angiogenesis and heart development...
  19. ncbi request reprint Two genes for de novo purine nucleotide synthesis on human chromosome 4 are closely linked and divergently transcribed
    K A Brayton
    Department of Biochemistry, Purdue University, West Lafayette, Indiana 47907
    J Biol Chem 269:5313-21. 1994
    ..Expression of a luciferase reporter from the GPAT promoter was approximately 3-4-fold higher than from the AIRC promoter. The GPAT gene was mapped to the q12 region of chromosome 4...
  20. ncbi request reprint Components of a new human protein kinase signal transduction pathway
    G Zhou
    Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor 48109 0606, USA
    J Biol Chem 270:12665-9. 1995
    ..Both MEK5 and ERK5 are expressed in many adult tissue and are abundant in heart and skeletal muscle. A recombinant GST-ERK5 kinase domain displays autophosphorylation on Ser/Thr and Tyr residues...