Research Topics
Genomes and Genes | Hong XuSummaryAffiliation: Fudan University Country: China Publications
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Publications
The effect of hepatitis B vaccination on the incidence of childhood HBV-associated nephritisHong Xu
Nephrology Department, Children s Hospital, Fudan University, 183 Feng Lin Road, Shanghai 200032, China
Pediatr Nephrol 18:1216-9. 2003..Furthermore, since childhood MN is associated with HBV, vaccination can also reduce the incidence of childhood MN...- Efficacy of urine screening at school: experience in Shanghai, ChinaYi Hui Zhai
Department of Nephrology, Children s Hospital of Fudan University, Shanghai, People s Republic of China
Pediatr Nephrol 22:2073-9. 2007..Asymptomatic chronic renal diseases in school children could be detected through school urine screening. For Shanghai, China, screening twice using method A might be the best choice... 
Thrombin facilitates invasion of ovarian cancer along peritoneum by inducing monocyte differentiation toward tumor-associated macrophage-like cellsTing Zhang
Department of Obstetrics and Gynecology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200001, China
Cancer Immunol Immunother 59:1097-108. 2010..Increased transcriptional activation of NF-kappaB p50/p65 was identified in thrombin-treated MOs. This study provided insight the role of thrombin in the regulation of EOC peritoneal invasion via "educating" MOs...- Clinicopathological features of paediatric renal biopsies in Shanghai over a 31 year periodYibing Zheng
Department of Nephrology and Rheumatism, Children s Hospital of Fudan University, Shanghai, China
Nephrology (Carlton) 17:274-7. 2012..To identify the variations in paediatric renal biopsy pathology and clinicopathological features during the past 31 years... - Tissue factor-factor VIIa complex induces epithelial ovarian cancer cell invasion and metastasis through a monocytes-dependent mechanismZhengwen Ma
Department of Neurobiology, Shanghai Jiaotong University School of Medicine, Shanghai, China
Int J Gynecol Cancer 21:616-24. 2011..However, it is not clear how tumor-associated macrophage and TF-FVIIa complex promotes EOC invasion. In the present study, we aimed to determine the mechanism by which interaction of TF-FVIIa and monocytes (MOs) promotes EOC metastasis... - Intrauterine growth restriction and postnatal high-protein diet affect the kidneys in adult ratsQian Shen
Department of Nephrology and Rheumatology, Children s Hospital of Fudan University, Shanghai, People s Republic of China
Nutrition 27:364-71. 2011..Postnatal overnutrition after IUGR may be of pathogenic importance for the development of diabetes and cardiovascular disease. This study was to identify the effects of IUGR and a postnatal high-protein diet on the kidneys in adult rats... - [Prohibitin suppresses renal interstitial fibroblasts proliferation and phenotypic change induced by transforming growth factor-beta1]Wei Guo
Department of Nephrology, Children s Hospital of Fudan University, Shanghai 200032, China
Zhonghua Yi Xue Za Zhi 87:1660-5. 2007..To illuminate the possible role of Prohibitin (PHB) in tubulointerstitial fibrosis... - [Long-term follow-up of 101 cases with pediatric lupus nephritis in a single center in Shanghai]Li Sun
Department of Nephrology and Rheumatology, Children s Hospital of Fudan University, Shanghai, China
Zhonghua Er Ke Za Zhi 49:819-24. 2011..To deeply understand prognosis of pediatric cases with lupus nephritis (LN) treated in our hospital and analyze the prognostic factors... - Effect of postnatal high-protein diet on kidney function of rats exposed to intrauterine protein restrictionJing Chen
Department of Nephrology, Children s Hospital, Fudan University, Shanghai 200032, People s Republic of China
Pediatr Res 68:100-4. 2010..This study suggests that postnatal HP diet amplifies the renal damage induced by fetal under-nutrition. Podocyte injury may be one of the mechanisms by which fetal protein restriction leads to proteinuria... - A comparative proteomic study of nephrogenesis in intrauterine growth restrictionQian Shen
Department of Nephrology and Rheumatology, Children s Hospital of Fudan University, 399 Wan Yuan Road, Minhang District, Shanghai, 201102, People s Republic of China
Pediatr Nephrol 25:1063-72. 2010.... - [Effect of hepatitis B vaccine immunization on HBV associated nephritis in children]Li Sun
Department of Nephrology, Children's Hospital, Fudan University, Shanghai 200032, China
Zhonghua Er Ke Za Zhi 41:666-9. 2003..Attention should be paid to interruption of maternal-infant transmission and serological follow-up should be performed in high-risk newborns after vaccination to further lower the incidence of hepatitis B virus associated nephritis... - [Clinical analysis of 139 cases of primary vesicoureteric reflux in children]Zhen Wang
Department of Kidney and Rheumatism, Children s Hospital of Fudan University, Shanghai 200032, China
Zhonghua Er Ke Za Zhi 46:518-21. 2008..To analyze the clinical features, renal damage and prognosis of primary vesicoureteric reflux (VUR) in children, hoping to give more attention to early recognition and treatment of the disease... - Angiopoietin-like protein 3 regulates the motility and permeability of podocytes by altering nephrin expression in vitroXia Gao
Department of Nephrology, Children s Hospital of Fudan University, Shanghai, China
Biochem Biophys Res Commun 399:31-6. 2010..In conclusion, we found ANGPTL3 to be capable of regulating the motility and permeability of podocytes and that the mechanism of ANGPTL3's regulation could be associated with the altered expression of nephrin... - [Analysis of the prognosis and clinical factors in primary vesicoureteral reflux patients]Jing Xu
Department of Nephrology and Rheumatology, Children s Hospital of Fudan University, Shanghai, China
Zhonghua Er Ke Za Zhi 50:587-92. 2012..To analyze the relationship between the prognosis and clinical factors of primary vesicoureteral reflux (VUR) patients under the condition of non-surgical treatment... - Long-term remission of recurrent severe anemia as a result of parvovirus B19 infection in a pediatric renal transplant recipientQian Shen
Department of Nephrology and Rheumatology, Children s Hospital of Fudan University, Shanghai, China
Pediatr Transplant 15:E76-9. 2011..In conclusion, PV-B19-associated anemia can be recurrent in immunocompromised children and baseline immunosuppression should be carefully adjusted to control PV-B19 infection... - [Comparison of cyclophosphamide and cyclosporine in the treatment of steroid-resistant idiopathic nephrotic syndrome in children]Jia Rao
Department of Pediatric Nephrology and Urology, Children s Hospital, Fudan University, Shanghai 200032, China
Zhong Nan Da Xue Xue Bao Yi Xue Ban 32:958-63. 2007..To compare the therapeutic outcome of cyclophosphamide(CTX) and cyclosporine A (CsA) in the treatment of steroid-resistant idiopathic nephrotic syndrome (SRNS) in children... - Expression of response gene to complement-32 in renal tissue of children with immunoglobulin A nephropathyXiao Ling Niu
Department of Nephrology and Rheumatology, Children s Hospital of Fudan University, Shanghai, PR China
Scand J Urol Nephrol 45:371-6. 2011..This study aimed to investigate the expression and significance of response gene to complement-32 (RGC-32) in renal tissue of children with immunoglobulin A nephropathy (IgAN)... 
A meta-analysis of interleukin-10-1082 promoter polymorphism associated with gastric cancer riskPeihua Ni
Department of Pharmacy, Shanghai Jiao Tong University School of Medicine, Shanghai, People s Republic of China
DNA Cell Biol 31:582-91. 2012..IL-10-1082 GG-plus-GA genotypes are more associated with the pathologically intestinal-type gastric cancer or anatomically cardia-type gastric cancer...- [Ambulatory blood pressure monitoring in pediatric patients with kidney diseases]Yin Zhu
Department of Nephrology, Children s Hostpital of Fudan University, Shanghai 200032, China
Zhonghua Er Ke Za Zhi 46:374-7. 2008..This study aimed to explore the characteristics of ABP in patients with common pediatric kidney diseases... - [Significance of polymorphisms in variable number of tandem repeat region of interleukin-4 gene in recurrence of childhood steroid sensitive nephrotic syndrome]Hai Mei Liu
Department of Nephrology, Children s Hospital of Fudan University, Shanghai 200032, China
Zhonghua Er Ke Za Zhi 43:431-3. 2005..The aim of this study was to investigate the association between the polymorphisms in variable numbers of tandem repeat region (VTR) of IL-4 gene and childhood SSNS... - [Long-term effects of cyclosporine A in children with steroid-resistant idiopathic nephrotic syndrome and outcomes of the patients]Qi Cao
Department of Nephrology, Pediatric Hospital, Fudan University, Shanghai 200032, China
Zhonghua Er Ke Za Zhi 46:698-701. 2008..To observe the effects of long-term cyclosporine A (CsA) treatment in 20 children with steroid-resistant idiopathic nephrotic syndrome (SRNS) and analyse the relevant influencing factors of CsA therapy... - Angiopoietin-like protein 3 modulates barrier properties of human glomerular endothelial cells through a possible signaling pathway involving phosphatidylinositol-3 kinase/protein kinase B and integrin alphaVbeta3Yunling Li
Department of Nephrology, Children s Hospital of Fudan University, Shanghai 200031, China
Acta Biochim Biophys Sin (Shanghai) 40:459-65. 2008..Our results also indicated that the integrin alphaVbeta3 antibody (LM609) could block the Angptl3-induced protein kinase B phosphorylation... - Serum starvation induces DRAM expression in liver cancer cells via histone modifications within its promoter locusPeihua Ni
Department of Pharmacy, Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China
PLoS ONE 7:e50502. 2012..These observations lay the ground for further investigation of the DRAM gene expression... - [Efficacy of acute (99m)Tc-dimercaptosuccinic acid scan in predicting vesicoureteral reflux among young children with febrile urinary tract infection]Xin Zhang
Department of Nephrology and Rheumatism, Children s Hospital of Fudan University, Shanghai 201102, China
Zhonghua Er Ke Za Zhi 48:334-7. 2010.... - Follow-up results of children with melamine induced urolithiasis: a prospective observational cohort studyJian Gao
Department of Nephrology, Children s Hospital of Fudan University, Shanghai, 201102, China
World J Pediatr 7:232-9. 2011..We hypothesized that urolithiasis induced by melamine-contaminated milk powder may be associated with secondary renal injury... - Proteomic analysis of human umbilical vein endothelial cells incubated with Cryptococcus neoformans var. neoformansXiao Jun Wang
Mycology Center and Department of Dermatology, Changzheng Hospital, Secondary Military Medical University, Shanghai, China
Mycoses 54:e336-43. 2011..neoformans. We hypothesise that these proteins take part in the modifications of HUVEC cytoskeleton and the tolerance to oxidative stress, which may affect the process of invasion by C. neoformans... - Staged-probability strategy of processing shotgun proteomic data to discover more functionally important proteinsHong Xu
State Key Laboratory of Microbial Metabolism Shanghai Jiao Tong University and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China
Protein Cell 3:140-7. 2012.... - The interaction of coagulation factor XII and monocyte/macrophages mediating peritoneal metastasis of epithelial ovarian cancerRuili Wang
Department of Obstetrics and Gynecology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200001, China
Gynecol Oncol 117:460-6. 2010..The aim of this study is to determine how the interaction between FXII and monocyte/macrophages (MO/MAs) contributes to EOC cell invasion and metastasis of the peritoneum... - Prohibitin suppresses renal interstitial fibroblasts proliferation and phenotypic change induced by transforming growth factor-beta1Wei Guo
Department of Nephrology, Children s Hospital of Fudan University, 183 Feng Lin Road, Shanghai, 200032, P R China
Mol Cell Biochem 295:167-77. 2007..Therefore, over-expression of PHB suppresses renal interstitial fibroblasts proliferation and cell phenotypic change induced by TGF-beta1, which indicates PHB as a potential therapeutic target to halt the progression of TIF... - [Risk factors of post-renal biopsy bleeding]Jian Ling Tao
Department of Nephrology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 30:313-7. 2008..To evaluate the risk factors of post-renal biopsy bleeding (PBB)... - Receiver-operating characteristic analyses of body mass index, waist circumference and waist-to-hip ratio for obesity: Screening in young adults in central south of ChinaFang Yang
Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha, Hunan 410081, PR China
Clin Nutr 25:1030-9. 2006..76-0.92) in both sexes and divided age groups (20-30-yr and 31-45-yr), and those for WHR were a little lower (0.74-0.88). CONCLUSIONS: BMI and WC are two important predictors for obesity in Chinese, and WHR is an alternative... - Identification of the amino acid residues in trichosanthin crucial for IgE responseXuan Cai
Laboratory of Molecular Immunology, Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, People's Republic of China
Biochem Biophys Res Commun 297:510-6. 2002..The data showed that the IgE epitope of TCS was determined and shown to play a critical role in induction of IgE, and the modification of IgE-epitope may be a useful strategy to reduce the allergenicity of an allergen... - [Influenza surveillance program in 2002-2003, in China]Hong Xu
Chinese National Influenza Center, Department of Influenza, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100052, China
Zhonghua Liu Xing Bing Xue Za Zhi 24:995-8. 2003..It seemed important to pay more attention to the variation of HA gene in influenza A type (H3N2) strains... - [Epidemiologic characteristics of influenza in China, from 2001 to 2003]Jing Zhang
Chinese Center of Disease Control and Prevention, Beijing 100050, China
Zhonghua Liu Xing Bing Xue Za Zhi 25:461-5. 2004..The change of the types of strains in the outbreaks during April to June in the southern China could provide data for better understanding on the trend of epidemics in the next season... - Authentication of stems of Dendrobium officinale by rDNA ITS region sequencesXiaoyu Ding
Planta Med 68:191-2. 2002..8S, and 3 in ITS2. These could be used as molecular characters to distinguish the stems of D. officinale from the adulterants... - Association between VDR ApaI polymorphism and hip bone mineral density can be modified by body mass index: a study on postmenopausal Chinese womenHong Xu
Laboratory of Molecular and Statistical Genetics, College of Life Sciences, Hunan Normal University, Changsha 410081, China
Acta Biochim Biophys Sin (Shanghai) 37:61-7. 2005..Our findings may partially explain the earlier inconsistent association results concerning the VDR gene and BMD, and highlight the importance of incorporating covariates such as BMI into osteoporosis association studies... - The (CA)n polymorphism of the TNFR2 gene is associated with peak bone density in Chinese nuclear familiesHong Xu
Laboratory of Molecular and Statistical Genetics, College of Life Sciences, Hunan Normal University, Changsha, Hunan, 410081, People s Republic of China
J Hum Genet 50:301-4. 2005..007). About 3.14% of lumbar spine BMD variation can be explained by the CA16 allele. In summary, our results suggest that the TNFR2 gene may play an important role in determining lumbar spine BMD variation in Chinese women... - Interaction effects between estrogen receptor alpha and vitamin D receptor genes on age at menarche in Chinese womenHong Xu
Laboratory of Molecular and Statistical Genetics, College of Life Sciences, Hu nan Normal University, Changsha 410081, China
Acta Pharmacol Sin 26:860-4. 2005..To evaluate whether estrogen receptor alpha (ER-alpha) and vitamin D receptor (VDR) genes are associated with the age at menarche in Chinese women... - Establishment of peak bone mineral density in Southern Chinese males and its comparisons with other males from different regions of ChinaLi Jun Tan
Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha, Hunan, PR China
J Bone Miner Metab 25:114-21. 2007..In conclusion, the PBMD at the spine and hip may be used as normal reference data for Southern Chinese males in Changsha instead of documented PBMD from other regions of China and the manufacturer's reference data... - [Expression of angiotensin II type 1 receptor in cervical squamous cell carcinoma and its clinical significance]Yan dan Liao
Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
Zhonghua Zhong Liu Za Zhi 29:360-4. 2007.... - Correlation and prediction of trunk fat mass with four anthropometric indices in Chinese malesSu-Mei Xiao
Laboratory of Molecular and Statistical Genetics, College of Life Sciences, Hunan Normal University, Changsha, Hunan 410081, PR China
Br J Nutr 96:949-55. 2006.... - Reassortant infectious bursal disease virus isolated in ChinaYongwei Wei
Institute of Preventive Veterinary Medicine, College of Animal Science, Zhejiang University, 268 Kaixuan Road, Hangzhou 310029, PR China
Virus Res 131:279-82. 2008..Our findings, which strongly suggest genetic exchange between attenuated and very virulent strains of IBDV, emphasizes the risk of generating uncontrolled chimeric viruses by using live attenuated vaccines... - [Evolutionary characterization of HA1 of influenza H1N1 hemagglutinin gene surveyed in 1981-2005 in China]Jia Huai Zhang
National Institute for Viral Disease Control and Prevention, China CDC, Beijing 100052, China
Bing Du Xue Bao 23:350-5. 2007..There appeared two groups of 2005 H1N1 virus strains that differed in time of virus isolation... - Evaluating the correlation and prediction of trunk fat mass with five anthropometric indices in Chinese females aged 20-40 yearsCheng Jiang
Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha, Hunan 410081, P R China
Nutr Metab Cardiovasc Dis 17:676-83. 2007..The early measurement of FM(trunk) has potential importance to evaluate trunk obesity. We sought to evaluate the correlation and predication of FM(trunk) with five anthropometric indices in Chinese females... - [Resistance to amantadine of epidemic strain of H3 subtype influenza virus: a primary study]Hong Xu
Institute for Viral Disease Control and Prevention, China Centre for Disease Control and Prevention, Beijing 100052, China
Zhonghua Yi Xue Za Zhi 86:996-8. 2006..CONCLUSION: The resistance rate to amantadine is high among the epidemic strains of H3 subtype influenza virus in China. The associated mutation occurs at the site 31 of M2 protein... - [Relationship between the distribution of hepatitis B virus genotypes and clinical types of the disease in Han nationality hepatitis B patients in Xinjiang]Hong Xu
Center of Hepatology, First Affiliated Hospital, Xinjiang Medical University, Wulumuqi 830054, China
Zhonghua Gan Zang Bing Za Zhi 13:848-9. 2005 - [Constitutive characteristics and change trend of gynecological malignant tumors in 8009 hospitalized patients in Guangxi Zhuang Autonomous Region]Wei Huang
Department of Gynecologic Oncology, Affiliated Cancer Hospital of Medical University of Guangxi, Nanning, China
Zhonghua Fu Chan Ke Za Zhi 42:22-5. 2007..To investigate the constitutive characteristics and the change trend of gynecologic malignant tumors in hospitalized patients in Guangxi Zhuang Autonomous Region over the recent 20 years...