Jun Wang

Summary

Affiliation: Fudan University
Country: China

Publications

  1. ncbi request reprint Beta-adrenoceptor mediated surgery-induced production of pro-inflammatory cytokines in rat microglia cells
    Jun Wang
    Department of Integrative Medicine and Neurobiology, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China
    J Neuroimmunol 223:77-83. 2010
  2. ncbi request reprint Electroacupuncture downregulates TLR2/4 and pro-inflammatory cytokine expression after surgical trauma stress without adrenal glands involvement
    Jun Wang
    Dept of Integrative Medicine Neurobiology, Institute of Acupuncture Research, WHO Collaborating Center for Traditional Medicine, State Key Laboratory of Medical Neurobiology, Fudan University, 138 Yi Xue Yuan Road, Shanghai, China
    Brain Res Bull 80:89-94. 2009
  3. doi request reprint Huperzine A ameliorates experimental autoimmune encephalomyelitis via the suppression of T cell-mediated neuronal inflammation in mice
    Jun Wang
    Department of Integrative Medicine and Neurobiology, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Institute of Acupuncture Research, WHO Collaborating Center for Traditional Medicine, Institutes of Brain Science, Fudan University, Shanghai 200032, China
    Exp Neurol 236:79-87. 2012
  4. doi request reprint Elevated transcriptional co-activator p102 mediates angiotensin II type 1 receptor up-regulation and extracellular matrix overproduction in the high glucose-treated rat glomerular mesangial cells and isolated glomeruli
    Zhen Wang
    Department of Physiology and Pathophysiology, Shanghai Medical College, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China
    Eur J Pharmacol 702:208-17. 2013
  5. pmc Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines
    Shan Hu
    Institute of Acupuncture Research WHO Collaborating Center for Traditional Medicine, School of Basic Medical Sciences, Shanghai Medical College, Institutes of Brain Science, Fudan University, 138 Yi Xue Yuan Road, PO Box 291, Shanghai 200032, China
    J Neuroinflammation 9:278. 2012
  6. pmc In vivo experimental study of hat type cervical intervertebral fusion cage (HCIFC)
    Yu Tong Gu
    Department of Orthopaedics, Zhongshan Hospital of Fudan University, Shanghai, China
    Int Orthop 34:1251-9. 2010
  7. doi request reprint Involvement of spinal neurotrophin-3 in electroacupuncture analgesia and inhibition of spinal glial activation in rat model of monoarthritis
    Wen Li Mi
    Department of Integrative Medicine and Neurobiology, Institute of Acupuncture Research, State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Shanghai Medical College, Fudan University, Shanghai, China
    J Pain 12:974-84. 2011
  8. ncbi request reprint Electroacupuncture combined with clomipramine enhances antidepressant effect in rodents
    Jin Yu
    Department of Integrative Medicine and Neurobiology, Institute of Acupuncture Research WHO Collaborating Center for Traditional Medicine, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Neurosci Lett 421:5-9. 2007
  9. ncbi request reprint A rat model of bone cancer pain induced by intra-tibia inoculation of Walker 256 mammary gland carcinoma cells
    Qi Liang Mao-Ying
    Department of Integrative Medicine and Neurobiology, Shanghai Medical College, Fudan University, China
    Biochem Biophys Res Commun 345:1292-8. 2006
  10. ncbi request reprint Sympathetic nervous system mediates surgical trauma stress-induced splenocyte apoptosis in rats
    Jun Wang
    Department of Integrative Medicine and Neurobiology, Shanghai Medical College, Fudan University, and Department of Pathology, Chang Zheng Hospital, Shanghai, 200032, China
    Eur J Pharmacol 565:76-82. 2007

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Beta-adrenoceptor mediated surgery-induced production of pro-inflammatory cytokines in rat microglia cells
    Jun Wang
    Department of Integrative Medicine and Neurobiology, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China
    J Neuroimmunol 223:77-83. 2010
    ..In conclusion, the results suggest that beta-ARs possess pro-inflammatory properties by modulating the functions of microglia cell...
  2. ncbi request reprint Electroacupuncture downregulates TLR2/4 and pro-inflammatory cytokine expression after surgical trauma stress without adrenal glands involvement
    Jun Wang
    Dept of Integrative Medicine Neurobiology, Institute of Acupuncture Research, WHO Collaborating Center for Traditional Medicine, State Key Laboratory of Medical Neurobiology, Fudan University, 138 Yi Xue Yuan Road, Shanghai, China
    Brain Res Bull 80:89-94. 2009
    ..EA inhibits TLR2/4 and pro-inflammatory cytokines to produce an anti-inflammatory effect in a surgical trauma stress model, without adrenal gland involvement...
  3. doi request reprint Huperzine A ameliorates experimental autoimmune encephalomyelitis via the suppression of T cell-mediated neuronal inflammation in mice
    Jun Wang
    Department of Integrative Medicine and Neurobiology, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Institute of Acupuncture Research, WHO Collaborating Center for Traditional Medicine, Institutes of Brain Science, Fudan University, Shanghai 200032, China
    Exp Neurol 236:79-87. 2012
    ..Therefore, HupA may have a potential therapeutic value for the treatment of multiple sclerosis and as a neuroimmunomodulatory drug to control human CNS pathology...
  4. doi request reprint Elevated transcriptional co-activator p102 mediates angiotensin II type 1 receptor up-regulation and extracellular matrix overproduction in the high glucose-treated rat glomerular mesangial cells and isolated glomeruli
    Zhen Wang
    Department of Physiology and Pathophysiology, Shanghai Medical College, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China
    Eur J Pharmacol 702:208-17. 2013
    ..The activation of RAS stimulates TGF-β1 and fibronectin production, which further results in ECM accumulation...
  5. pmc Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines
    Shan Hu
    Institute of Acupuncture Research WHO Collaborating Center for Traditional Medicine, School of Basic Medical Sciences, Shanghai Medical College, Institutes of Brain Science, Fudan University, 138 Yi Xue Yuan Road, PO Box 291, Shanghai 200032, China
    J Neuroinflammation 9:278. 2012
    ..In this study, we investigated the effects of intrathecal injection with lipoxin and related analogues on CIBP in rats...
  6. pmc In vivo experimental study of hat type cervical intervertebral fusion cage (HCIFC)
    Yu Tong Gu
    Department of Orthopaedics, Zhongshan Hospital of Fudan University, Shanghai, China
    Int Orthop 34:1251-9. 2010
    ..HCIFC can provide a good intervertebral distractability and sufficient biomechanical stability for cervical fusion...
  7. doi request reprint Involvement of spinal neurotrophin-3 in electroacupuncture analgesia and inhibition of spinal glial activation in rat model of monoarthritis
    Wen Li Mi
    Department of Integrative Medicine and Neurobiology, Institute of Acupuncture Research, State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Shanghai Medical College, Fudan University, Shanghai, China
    J Pain 12:974-84. 2011
    ..These results suggested that endogenous NT-3 may be involved in the analgesic effect of EA on inflammatory pain in rats, mediated through the inhibition of spinal glial activity as well as proinflammatory cytokine production...
  8. ncbi request reprint Electroacupuncture combined with clomipramine enhances antidepressant effect in rodents
    Jin Yu
    Department of Integrative Medicine and Neurobiology, Institute of Acupuncture Research WHO Collaborating Center for Traditional Medicine, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Neurosci Lett 421:5-9. 2007
    ..5mg/kg CLO alone. These results demonstrated that EA combined with CLO at low doses has an additive or synergistic antidepressant action, and this combination may provide an effective strategy for depression management...
  9. ncbi request reprint A rat model of bone cancer pain induced by intra-tibia inoculation of Walker 256 mammary gland carcinoma cells
    Qi Liang Mao-Ying
    Department of Integrative Medicine and Neurobiology, Shanghai Medical College, Fudan University, China
    Biochem Biophys Res Commun 345:1292-8. 2006
    ..In summary, the present study provided a useful and easily established rat model of bone cancer pain which will contribute to further study of the mechanisms underlying cancer pain...
  10. ncbi request reprint Sympathetic nervous system mediates surgical trauma stress-induced splenocyte apoptosis in rats
    Jun Wang
    Department of Integrative Medicine and Neurobiology, Shanghai Medical College, Fudan University, and Department of Pathology, Chang Zheng Hospital, Shanghai, 200032, China
    Eur J Pharmacol 565:76-82. 2007
    ..The data clearly revealed that the sympathetic nervous system especially beta-adrenergic receptors was involved in surgical trauma-induced immune alterations via a mechanism of apoptotic cell death...
  11. pmc Suppression of XBP1S mediates high glucose-induced oxidative stress and extracellular matrix synthesis in renal mesangial cell and kidney of diabetic rats
    Decui Shao
    Department of Physiology and Pathophysiology, Shanghai Medical College, Fudan University, Shanghai, China
    PLoS ONE 8:e56124. 2013
    ..These results suggested that XBP1S pathway of ER stress was involved in HG-induced oxidative stress and ECM synthesis. A downstream target of XBP1S in regulating ROS formation might be NADPH oxidase...
  12. doi request reprint Neuron-glial cell communication in the traumatic stress-induced immunomodulation
    Hui Zhao
    Department of Integrative Medicine and Neurobiology, Shanghai Medical College, Fudan University, Shanghai 200032, People s Republic of China
    Synapse 65:433-40. 2011
    ..ERK1/2-signaling events are required for the temporal and spatial coordination between neuron and glial cells...
  13. ncbi request reprint Changes in expression of nociceptin/orphanin FQ and its receptor in spinal dorsal horn during electroacupuncture treatment for peripheral inflammatory pain in rats
    Xin Fu
    Institute of Acupuncture Research, Institutes of Brain Science, Fudan University, Shanghai 200032, China
    Peptides 28:1220-8. 2007
    ..The present data demonstrated that EA could activate the endogenous N/OFQ-NOP receptor system, and this might underlie the effectiveness of EA in the treatment of inflammatory pain...
  14. ncbi request reprint Stage-dependent analgesia of electro-acupuncture in a mouse model of cutaneous cancer pain
    Qi Liang Mao-Ying
    Department of Integrative Medicine and Neurobiology, Institute of Acupuncture Research, Shanghai Medical College, Fudan University, Post Box 291, 138 Yi Xue Yuan Road, Shanghai 200032, China
    Eur J Pain 10:689-94. 2006
    ..The results demonstrated that EA had anti-hyperalgesic effect on early stage of cutaneous cancer pain but not on late stage. These results indicated a tight correlation of EA anti-hyperalgesic effects with the time window of cancer pain...
  15. doi request reprint Predicting subcellular location of apoptosis proteins with pseudo amino acid composition: approach from amino acid substitution matrix and auto covariance transformation
    Xiaoqing Yu
    Department of Mathematics, Shanghai Normal University, 200234, Shanghai, China
    Amino Acids 42:1619-25. 2012
    ..The results obtained by jackknife test are quite promising, indicating that the proposed method might serve as a potential and efficient prediction model for apoptosis protein subcellular location prediction...
  16. pmc Prioritization of candidate disease genes by topological similarity between disease and protein diffusion profiles
    Jie Zhu
    Department of Mathematics, Shanghai Normal University, Shanghai, China
    BMC Bioinformatics 14:S5. 2013
    ..A recent comparative study showed that diffusion-based methods achieve the state-of-the-art predictive performance...
  17. ncbi request reprint Electroacupuncture suppresses surgical trauma stress-induced lymphocyte apoptosis in rats
    Jun Wang
    Department of Integrative Medicine and Neurobiology, Institute of Acupuncture Research, Shanghai Medical College, Fudan University, PR China
    Neurosci Lett 383:68-72. 2005
    ..These results implied that EA could decrease splenic lymphocytes apoptosis via inhibiting Fas protein expression; consequently prevent deleterious immunological changes in the post-operative state...
  18. ncbi request reprint SOAPfusion: a robust and effective computational fusion discovery tool for RNA-seq reads
    Jikun Wu
    Department of Computer Science, The University of Hong Kong, Hong Kong, China, BGI Shenzhen, Shenzhen, China, Department of Biology, University of Copenhagen, Copenhagen, Denmark, King Abdulaziz University, Jeddah, Saudi Arabia, The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen and Guangzhou Key Laboratory of Cancer Trans Omics Research, BGI Guangzhou, Guangzhou, China
    Bioinformatics 29:2971-8. 2013
    ..Most of the existing computational fusion detection tools are challenged by the issues of accuracy and how to handle multiple mappings...
  19. ncbi request reprint Regulation of transforming growth factor-beta 1-induced apoptosis and epithelial-to-mesenchymal transition by protein kinase A and signal transducers and activators of transcription 3
    Yanan Yang
    Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    Cancer Res 66:8617-24. 2006
    ..These studies provided a new insight into the signaling mechanism underlying the apoptosis and EMT, which could be of importance in understanding some related physiologic and pathologic processes...
  20. doi request reprint The feasibility of using a baculovirus vector to deliver the sodium-iodide symporter gene as a reporter
    Xiang Zhou
    Department of Nuclear Medicine, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
    Nucl Med Biol 37:299-308. 2010
    ....
  21. doi request reprint Characterization of Fyn signaling on the age-dependent immuno-modulation on traumatic rats
    Sheng Xiao
    Department of Integrative Medicine and Neurobiology, National Key Lab of Medical Neurobiology, Institute of Brain Research Sciences, Fudan University, 138 Yixueyuan Rd Box 291, Shanghai, 200032, PR China
    Brain Res 1255:162-9. 2009
    ..Taken together, the data indicated that immunological processes in response to traumatic stress was age dependent, Fyn-ERK1/2 signal pathway was required to convey the recovery signals...
  22. pmc Reconstruction of the abdominal vagus nerve using sural nerve grafts in canine models
    Jingbo Liu
    Department of Hand Surgery, Huashan Hospital, Fudan University, Shanghai, China
    PLoS ONE 8:e58903. 2013
    ..Recently, vagus nerve preservation or reconstruction of vagus has received increasing attention. The present study aimed to investigate the feasibility of reconstructing the severed vagal trunk using an autologous sural nerve graft...
  23. ncbi request reprint [In vivo experimental study of hat type cervical intervertebral fusion cage]
    Yu Tong Gu
    Department of Orthopaedics, Zhongshan Hospital of Fudan University, Shanghai 200032, China
    Zhonghua Wai Ke Za Zhi 44:1127-31. 2006
    ..To compare the characteristics of interbody fusion achieved using hat type cervical intervertebral fusion cage (HCIFC) with those of an autologous tricortical iliac crest graft, Harms cage and Carbon cage in a goat cervical spine model...
  24. doi request reprint MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo
    Bo Liu
    Cardiovascular Department, Changhai Hospital, Shanghai, China
    Lung Cancer 66:169-75. 2009
    ..8035+/-0.1521 to 0.6235+/-0.0757g, with the inhibitive rate being 22.4%. All these results revealed that miR-126 may have a tumor suppressor function in lung cancer cells and could be a promising treatment in anticancer therapy...
  25. doi request reprint Aberrant survivin expression in endometrial hyperplasia: another mechanism of progestin resistance
    Xiaojun Chen
    Department of Gynecology, Obstetrics and Gynecology Hospital, Shanghai Medical College Fudan University, Shanghai, China
    Mod Pathol 22:699-708. 2009
    ..Intermittent, rather than continuous, progestin treatment may be more effective clinically for the treatment of endometrial hyperplasia...
  26. doi request reprint Prediction of regulatory interactions in Arabidopsis using gene-expression data and support vector machines
    Xiaoqing Yu
    Department of Mathematics, Shanghai Normal University, Shanghai, China
    Plant Physiol Biochem 49:280-3. 2011
    ..68%. Our approach could help to widen the understanding of Arabidopsis gene regulatory scheme and may offer a cost-effective alternative to construct the gene regulatory network...
  27. doi request reprint Self-assembly of all-conjugated poly(3-alkylthiophene) diblock copolymer nanostructures from mixed selective solvents
    Ming He
    The Key Laboratory of Molecular Engineering of Polymers, Ministry of Education, Department of Macromolecular Science, Fudan University, Shanghai 200433, China
    ACS Nano 4:3241-7. 2010
    ....
  28. doi request reprint Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells
    Hong Xue
    Department of Physiology and Pathophysiology, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Regul Pept 177:12-20. 2012
    ..These results suggest that Ang-(1-7) and Ang II specifically interact with each other on rat renal MCs via activation of their specific receptors, Mas and AT1 receptor respectively...