Affiliation: Fudan University
Wang F, Jiang L, Chen Y, Haelterman N, Bellen H, Chen R. FlyVar: a database for genetic variation in Drosophila melanogaster. Database (Oxford). 2015;2015: pubmed publisher
..melanogaster strains to identify candidate mutations. FlyVar permits the analysis of next generation sequencing data without the need of extensive computational training or resources. Database URL: www.iipl.fudan.edu.cn/FlyVar. ..
Li Z, Wang Y, Wang F. A study on fast calling variants from next-generation sequencing data using decision tree. BMC Bioinformatics. 2018;19:145 pubmed publisher
..We also conducted additional experiments on the WGS data of 4 newly released samples that have not been used to populate dbSNP. ..
Chen Y, Zhao L, Wang Y, Cao M, Gelowani V, Xu M, et al
. SeqCNV: a novel method for identification of copy number variations in targeted next-generation sequencing data. BMC Bioinformatics. 2017;18:147 pubmed publisher
..SeqCNV is able to robustly identify CNVs of different size using capture NGS data. Compared with other CNV-calling methods, SeqCNV shows a significant improvement in both sensitivity and specificity. ..
Liu S, Wang Y, Wang F. A fast read alignment method based on seed-and-vote for next generation sequencing. BMC Bioinformatics. 2016;17:466 pubmed publisher
..In some cases, reads have to be aligned in a short time. Where requirement of accuracy is not very stringent, FSVA would be a promising option. FSVA is available at https://github.com/Topwood91/FSVA. ..