Lan Ma

Summary

Affiliation: Fudan University
Country: China

Publications

  1. doi request reprint Post-endocytic fates of delta-opioid receptor are regulated by GRK2-mediated receptor phosphorylation and distinct beta-arrestin isoforms
    Xiaoqing Zhang
    Pharmacology Research Center and National Laboratory of Medical Neurobiology, Shanghai Medical College and Institutes of Brain Science, Fudan University, Shanghai, China
    J Neurochem 106:781-92. 2008
  2. ncbi request reprint Beta-arrestin signaling and regulation of transcription
    Lan Ma
    Pharmacology Research Center, Shanghai Medical College and Institutes of Brain Science, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, China
    J Cell Sci 120:213-8. 2007
  3. ncbi request reprint Decreased morphine analgesia in rat overexpressing beta-arrestin 2 at periaqueductal gray
    Baohong Jiang
    Pharmacology Research Center and Department of Pharmacology, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Neurosci Lett 400:150-3. 2006
  4. ncbi request reprint The effect of L-stepholidine, a novel extract of Chinese herb, on the acquisition, expression, maintenance, and re-acquisition of morphine conditioned place preference in rats
    Wei Wang
    Pharmacology Research Center, Shanghai Medical College and Institutes of Brain Science, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, China
    Neuropharmacology 52:355-61. 2007
  5. ncbi request reprint Single and repeated morphine administrations differently regulate expression of N-ethylmaleimide-sensitive factor gene in the rat brain
    Haohong Li
    Pharmacology Research Center, Department of Pharmacology, Shanghai Medical College Fudan University, Shanghai, China
    Neuroreport 17:71-4. 2006
  6. pmc Regulation of amygdalar PKA by beta-arrestin-2/phosphodiesterase-4 complex is critical for fear conditioning
    Yuting Li
    The State Key Laboratory of Medical Neurobiology, Shanghai Medical College and Institutes of Brain Science, Fudan University, Shanghai 200032, China
    Proc Natl Acad Sci U S A 106:21918-23. 2009
  7. ncbi request reprint Agonist-induced formation of opioid receptor-G protein-coupled receptor kinase (GRK)-G beta gamma complex on membrane is required for GRK2 function in vivo
    Jiali Li
    National Laboratory of Medical Neurobiology, Shanghai Medical College and Institutes of Brain Science, Fudan University, Shanghai 200032, China
    J Biol Chem 278:30219-26. 2003
  8. pmc EGF transregulates opioid receptors through EGFR-mediated GRK2 phosphorylation and activation
    Yuejun Chen
    Pharmacology Research Center and State Key Laboratory of Medical Neurobiology, Shanghai Medical College and Institutes of Brain Science, Fudan University, Shanghai 200032, China
    Mol Biol Cell 19:2973-83. 2008
  9. ncbi request reprint Up-regulation of murine double minute clone 2 (MDM2) gene expression in rat brain after morphine, heroin, and cocaine administrations
    Yan Jiang
    National Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Neurosci Lett 352:216-20. 2003
  10. ncbi request reprint Different roles of dopamine receptor subtypes in footshock stress-induced enhancement of morphine conditioned place preference
    Zhengze Dai
    Pharmacology Research Center, Shanghai Medical College and Institutes of Brain Science, Fudan University, Shanghai 200032, PR China
    Neurosci Lett 409:52-6. 2006

Collaborators

  • Yu Qui Zhang
  • Baohong Jiang
  • Wei Wang
  • Xin Ge
  • Blanca Camoretti-Mercado
  • Jiuhong Kang
  • P Wang
  • Yan Jiang
  • Jing Li
  • Yuejun Chen
  • Lin Lu
  • Haohong Li
  • Xiaoqing Zhang
  • Yuting Li
  • Gang Pei
  • Guobin Bao
  • Xi Jiang
  • Lin Kang
  • Wen Yue
  • Lu Pu
  • Ziyan Wu
  • Peng Xia
  • Yuqing Zhou
  • Xiaoqing Chen
  • Feifei Wang
  • Zhengze Dai
  • Michael T Roberts
  • Jingxia Gao
  • Min Zhu
  • Nan Jie Xu
  • Yue Sun
  • Xing Liu
  • Chunfu Wu
  • Yezheng Tao
  • Baoming Li
  • Hui Long
  • Beth S Erlichman
  • Lei Wang
  • Rachel Phelan
  • Gregory F Lopreato
  • S John Mihic
  • Rathi N Pillai
  • Fen Su
  • Bao Ming Li
  • Bin Xiang
  • Hai Chen
  • Wenjuan Su
  • Xue Liang Fan
  • Wei Lin Yang
  • Zhijie Cheng
  • Wen Juan Su
  • Guo Bin Bao

Detail Information

Publications26

  1. doi request reprint Post-endocytic fates of delta-opioid receptor are regulated by GRK2-mediated receptor phosphorylation and distinct beta-arrestin isoforms
    Xiaoqing Zhang
    Pharmacology Research Center and National Laboratory of Medical Neurobiology, Shanghai Medical College and Institutes of Brain Science, Fudan University, Shanghai, China
    J Neurochem 106:781-92. 2008
    ..Thus, the post-endocytic fate of internalized DOR can be regulated by GRK2-catalyzed receptor phosphorylation as well as distinct beta-arrestin isoforms...
  2. ncbi request reprint Beta-arrestin signaling and regulation of transcription
    Lan Ma
    Pharmacology Research Center, Shanghai Medical College and Institutes of Brain Science, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, China
    J Cell Sci 120:213-8. 2007
    ..This beta-arrestin-mediated regulation of transcription appears to play important roles in cell growth, apoptosis and modulation of immune functions...
  3. ncbi request reprint Decreased morphine analgesia in rat overexpressing beta-arrestin 2 at periaqueductal gray
    Baohong Jiang
    Pharmacology Research Center and Department of Pharmacology, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Neurosci Lett 400:150-3. 2006
    ..These findings support the notion that PAG is an important site where beta-arrestin 2 plays its regulatory effects on morphine analgesia...
  4. ncbi request reprint The effect of L-stepholidine, a novel extract of Chinese herb, on the acquisition, expression, maintenance, and re-acquisition of morphine conditioned place preference in rats
    Wei Wang
    Pharmacology Research Center, Shanghai Medical College and Institutes of Brain Science, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, China
    Neuropharmacology 52:355-61. 2007
    ..These results demonstrate that SPD can inhibit acquisition, maintenance, and re-acquisition of morphine conditioned place preference and suggest its potential for treatment of opioid addiction...
  5. ncbi request reprint Single and repeated morphine administrations differently regulate expression of N-ethylmaleimide-sensitive factor gene in the rat brain
    Haohong Li
    Pharmacology Research Center, Department of Pharmacology, Shanghai Medical College Fudan University, Shanghai, China
    Neuroreport 17:71-4. 2006
    ..These findings suggest that the N-ethylmaleimide-sensitive factor may be involved in the maladaptive changes in the nervous system after opiate treatment...
  6. pmc Regulation of amygdalar PKA by beta-arrestin-2/phosphodiesterase-4 complex is critical for fear conditioning
    Yuting Li
    The State Key Laboratory of Medical Neurobiology, Shanghai Medical College and Institutes of Brain Science, Fudan University, Shanghai 200032, China
    Proc Natl Acad Sci U S A 106:21918-23. 2009
    ..Taken together, our data demonstrate that the feedback regulation of amygdalar PKA activation by beta-arrestin-2 and PDE-4 complex is critical for the formation of conditioned fear memory...
  7. ncbi request reprint Agonist-induced formation of opioid receptor-G protein-coupled receptor kinase (GRK)-G beta gamma complex on membrane is required for GRK2 function in vivo
    Jiali Li
    National Laboratory of Medical Neurobiology, Shanghai Medical College and Institutes of Brain Science, Fudan University, Shanghai 200032, China
    J Biol Chem 278:30219-26. 2003
    ....
  8. pmc EGF transregulates opioid receptors through EGFR-mediated GRK2 phosphorylation and activation
    Yuejun Chen
    Pharmacology Research Center and State Key Laboratory of Medical Neurobiology, Shanghai Medical College and Institutes of Brain Science, Fudan University, Shanghai 200032, China
    Mol Biol Cell 19:2973-83. 2008
    ..These data indicate that EGF transregulates opioid receptors through EGFR-mediated tyrosyl phosphorylation and activation of GRK2 and propose GRK2 as a mediator of cross-talk from RTK to GPCR signaling pathway...
  9. ncbi request reprint Up-regulation of murine double minute clone 2 (MDM2) gene expression in rat brain after morphine, heroin, and cocaine administrations
    Yan Jiang
    National Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Neurosci Lett 352:216-20. 2003
    ....
  10. ncbi request reprint Different roles of dopamine receptor subtypes in footshock stress-induced enhancement of morphine conditioned place preference
    Zhengze Dai
    Pharmacology Research Center, Shanghai Medical College and Institutes of Brain Science, Fudan University, Shanghai 200032, PR China
    Neurosci Lett 409:52-6. 2006
    ..These results indicate that dopamine D(1), D(2), and D(3) receptor subtypes play different roles in footshock stress-induced enhancement of morphine conditioned place preference...
  11. ncbi request reprint Metabolic enzymes link morphine withdrawal with metabolic disorder
    Xi Jiang
    National Laboratory of Medical Neurobiology and Pharmacology Research Center, Shanghai Medical College and Institutes of Brain Science, Fudan University, Shanghai, China
    Cell Res 17:741-3. 2007
  12. ncbi request reprint Beta-arrestin1 and beta-arrestin2 are differentially required for phosphorylation-dependent and -independent internalization of delta-opioid receptors
    Xiaoqing Zhang
    Pharmacology Research Center, Shanghai Medical College, Shanghai, China
    J Neurochem 95:169-78. 2005
    ..These results thus provide the first evidence of different requirement for beta-arrestin isoforms in the agonist induced phosphorylation-dependent and -independent GPCR internalization...
  13. doi request reprint Chronic, but not acute morphine treatment, up-regulates alpha-Ca2+/calmodulin dependent protein kinase II gene expression in rat brain
    Yuejun Chen
    Pharmacology Research Center and State Key Laboratory of Medical Neurobiology, Shanghai Medical College and Institutes of Brain Science, Fudan University, Shanghai 200032, China
    Neurochem Res 33:2092-8. 2008
    ..Taken together, our data demonstrate that chronic morphine treatment region-specific up-regulates the levels of the alpha-CaMK II gene expression in hippocampus and frontal cortex...
  14. ncbi request reprint Role of withdrawal in reinstatement of morphine-conditioned place preference
    Lin Lu
    National Laboratory of Medical Neurobiology and Pharmacology Research Center, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, China
    Psychopharmacology (Berl) 181:90-100. 2005
    ..However, the role of withdrawal in relapse has not yet been systemically investigated in the reinstatement model...
  15. ncbi request reprint [Regulation of G protein-coupled receptor kinase 5 mRNA and protein level in rat brain by addictive drugs]
    Min Zhu
    Pharmacological Research Center, Shanghai Medical College, Fudan University, State Key Lab of Medical Neurobiology, China
    Sheng Li Xue Bao 56:559-65. 2004
    ..01), Taken together, our results indicate that addictive drugs can regulate GRK5 in the rat brain on protein level as well as on mRNA level and suggest that GRK5 may play a role in addiction of psychoactive substances...
  16. ncbi request reprint Regulation of EGF-induced ERK/MAPK activation and EGFR internalization by G protein-coupled receptor kinase 2
    Jingxia Gao
    Pharmacology Research Center, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Acta Biochim Biophys Sin (Shanghai) 37:525-31. 2005
    ....
  17. ncbi request reprint A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription
    Jiuhong Kang
    Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, The Graduate School, Chinese Academy of Sciences, Shanghai 200031, China
    Cell 123:833-47. 2005
    ....
  18. ncbi request reprint Beta-arrestin 2 functions as a G-protein-coupled receptor-activated regulator of oncoprotein Mdm2
    Ping Wang
    Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, People s Republic of China
    J Biol Chem 278:6363-70. 2003
    ..Our study thus suggests that beta-arrestin 2 may serve as a cross-talk linker between GPCR and p53 signaling pathways...
  19. ncbi request reprint Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation
    Yue Sun
    Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, People s Republic of China
    J Biol Chem 277:49212-9. 2002
    ....
  20. ncbi request reprint Morphine and heroin differentially modulate in vivo hippocampal LTP in opiate-dependent rat
    Guobin Bao
    Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People s Republic of China
    Neuropsychopharmacology 32:1738-49. 2007
    ....
  21. ncbi request reprint Inhibition of transforming growth factor beta-enhanced serum response factor-dependent transcription by SMAD7
    Blanca Camoretti-Mercado
    Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    J Biol Chem 281:20383-92. 2006
    ..Our findings thus reveal that SRF-Smad7 interactions in part mediate TGFbeta regulation of gene transcription in airway smooth muscle. This offers potential targets for interventions in treating lung inflammation and asthma...
  22. ncbi request reprint Occupancy of a single anesthetic binding pocket is sufficient to enhance glycine receptor function
    Michael T Roberts
    Waggoner Center for Alcohol and Addiction Research, Section of Neurobiology, Institutes for Neuroscience and Cell and Molecular Biology, The University of Texas at Austin, Austin, Texas 78712
    J Biol Chem 281:3305-11. 2006
    ....
  23. ncbi request reprint Analysis of opioid-induced kinase activation
    Lan Ma
    National Laboratory of Medical Neurobiology, Fudan University Medical Center, Shanghai, China
    Methods Mol Med 84:39-46. 2003
  24. ncbi request reprint Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminus
    Ping Wang
    Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, People s Republic of China
    J Biol Chem 278:11648-53. 2003
    ....
  25. ncbi request reprint Hippocampal long-term potentiation is reduced by chronic opiate treatment and can be restored by re-exposure to opiates
    Lu Pu
    Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, People s Republic of China
    J Neurosci 22:1914-21. 2002
    ..These findings demonstrated that chronic opiate treatment can significantly modulate synaptic plasticity in the hippocampus, leading to an opiate dependence of the plasticity...
  26. ncbi request reprint Reactivation of morphine conditioned place preference by drug priming: role of environmental cues and sensitization
    Lin Lu
    National Laboratory of Medical Neurobiology, Fudan University Medical Center, Shanghai, China
    Psychopharmacology (Berl) 159:125-32. 2002
    ..Despite a great deal of research, the exact factors that determine renewed drug-seeking and persistent craving for them remain unclear...