Ming Qing Li
Affiliation: Fudan University
Mei J, Zhu X, Jin L, Duan Z, Li D, Li M. Estrogen promotes the survival of human secretory phase endometrial stromal cells via CXCL12/CXCR4 up-regulation-mediated autophagy inhibition. Hum Reprod. 2015;30:1677-89 pubmed publisher
..None of the authors has any conflict of interest to declare. ..
Li H, Meng Y, Shang W, Liu L, Chen X, Yuan M, et al
. Chemokine CCL24 promotes the growth and invasiveness of trophoblasts through ERK1/2 and PI3K signaling pathways in human early pregnancy. Reproduction. 2015;150:417-27 pubmed publisher
..Thus, our results provide a possible explanation for the growth and invasion of trophoblasts in human embryo implantation. ..
Yu J, Sun H, Zhang Z, Shi R, Liu L, Shang W, et al
. IL15 promotes growth and invasion of endometrial stromal cells and inhibits killing activity of NK cells in endometriosis. Reproduction. 2016;152:151-60 pubmed publisher
..On the other hand, IL15 may help the immune escape of ESCs by suppressing the cytotoxic activity of NK cells in the ectopic milieu, thereby facilitating the progression of EMS. ..
Shao J, Zhang B, Yu J, Wei C, Zhou W, Chang K, et al
. Macrophages promote the growth and invasion of endometrial stromal cells by downregulating IL-24 in endometriosis. Reproduction. 2016;152:673-682 pubmed
..These results indicate that the abnormally low level of IL-24 in ESCs possibly induced by macrophages may lead to the enhancement of ESCs' proliferation and invasiveness and contribute to the development of endometriosis. ..
Zhou W, Yang H, Shao J, Mei J, Chang K, Zhu R, et al
. Anti-inflammatory cytokines in endometriosis. Cell Mol Life Sci. 2019;: pubmed publisher
Chang R, Shao J, Meng Y, Wang J, Li D, Li M. Decidual RANKL/RANK interaction promotes the residence and polarization of TGF-β1-producing regulatory γδ T cells. Cell Death Dis. 2019;10:113 pubmed publisher
..This observation provides a scientific basis on which a potential marker can be detected to early warning of pregnancy loss. ..
Liu X, Sun H, Zhang Z, Shi R, Liu L, Yu J, et al
. Indoleamine 2,3-dioxygenase suppresses the cytotoxicity of 1 NK cells in response to ectopic endometrial stromal cells in endometriosis. Reproduction. 2018;156:397-404 pubmed publisher
Xie F, Liu L, Shang W, Chang K, Meng Y, Mei J, et al
. The infiltration and functional regulation of eosinophils induced by TSLP promote the proliferation of cervical cancer cell. Cancer Lett. 2015;364:106-17 pubmed publisher
..This provides a scientific basis on which potential therapeutic strategies could be targeted to cervical cancer, especially for patients with massive infiltrations of EOS. ..
Zhang B, Zhou W, Gu C, Wu K, Yang H, Mei J, et al
. The ginsenoside PPD exerts anti-endometriosis effects by suppressing estrogen receptor-mediated inhibition of endometrial stromal cell autophagy and NK cell cytotoxicity. Cell Death Dis. 2018;9:574 pubmed publisher
..This result provides a scientific basis for potential therapeutic strategies to treat EMS by PPD or further structural modification. ..