Affiliation: Fudan University
Fang X, Zhao Q, Cao H, Liu J, Guan M, Kong J. Rapid detection of Cu(2+) by a paper-based microfluidic device coated with bovine serum albumin (BSA)-Au nanoclusters. Analyst. 2015;140:7823-6 pubmed publisher
..This sensor could test Cu(2+) rapidly with high specificity and sensitivity, which would be useful for point-of-care testing (POCT). ..
Fang X, Zhao Q, Cao H, Liu J, Guan M, Kong J. Correction: Rapid detection of Cu(2+) by a paper-based microfluidic device coated with bovine serum albumin (BSA)-Au nanoclusters. Analyst. 2015;140:8217 pubmed publisher
..Correction for 'Rapid detection of Cu(2+) by a paper-based microfluidic device coated with bovine serum albumin (BSA)-Au nanoclusters' by Xueen Fang, et al., Analyst, 2015, 140, 7823-7826. ..
Liu P, Fang X, Cao H, Gu M, Kong J, Deng A. Magnetic-bioluminescent-nanoliposomes for ultrasensitive and portable detection of protein biomarkers in blood. Anal Chim Acta. 2018;1039:98-107 pubmed publisher
..Thus, our LBM assay holds great potential as a POCT assay for use in clinical diagnostics. ..
Ye X, Xu J, Lu L, Li X, Fang X, Kong J. Equipment-free nucleic acid extraction and amplification on a simple paper disc for point-of-care diagnosis of rotavirus A. Anal Chim Acta. 2018;1018:78-85 pubmed publisher
..In conclusion, the present paper-based test fulfills the main requirements for a point-of-care diagnostic tool, and has the potential to be applied to disease prevention, control, and precision diagnosis. ..
Zhang P, Kong J. Doxorubicin-tethered fluorescent silica nanoparticles for pH-responsive anticancer drug delivery. Talanta. 2015;134:501-7 pubmed publisher
..The fluorescence of the FSiNPs also allowed the live-tracking of the nanoparticles in the cell. ..
Wang H, Chen H, Huang Z, Li T, Deng A, Kong J. DNase I enzyme-aided fluorescence signal amplification based on graphene oxide-DNA aptamer interactions for colorectal cancer exosome detection. Talanta. 2018;184:219-226 pubmed publisher
..The method was verified in 19 clinical blood serum samples to distinguish healthy and CRC patients, showing significant diagnostic power. Moreover, it can be expanded to other kinds of cancer exosomes, in addition to CRC. ..
Li H, Fang X, Cao H, Kong J. Paper-based fluorescence resonance energy transfer assay for directly detecting nucleic acids and proteins. Biosens Bioelectron. 2016;80:79-83 pubmed publisher
..This paper-based microfluidics chip has been applied in the detection of proteins and nucleic acids. The biosensing capability meets many potential requirements for disease diagnosis and biological analysis. ..
Liu P, Fang X, Cao H, Gu M, Kong J, Deng A. Nano-biotinylated liposome-based immunoassay for the ultrasensitive detection of protein biomarker in urine. Talanta. 2018;179:472-477 pubmed publisher
..LI-LAMP shows good potential as a clinical diagnostic assay. ..
Cao H, Fang X, Li H, Li H, Kong J. Ultrasensitive detection of mucin 1 biomarker by immuno-loop-mediated isothermal amplification. Talanta. 2017;164:588-592 pubmed publisher
..Finally, this approach is also successfully applied in the analysis of human blood serum samples. It also lays the foundation for the early diagnosis of different types of low-abundance cancer biomarkers. ..