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Affiliation: Fudan University
Yang T, Zhang H, Liang Q, Shi Y, Mei Y, Barrett P, et al. Small-Conductance Ca2+-Activated Potassium Channels Negatively Regulate Aldosterone Secretion in Human Adrenocortical Cells. Hypertension. 2016;68:785-95 pubmed publisher
..Genetic association studies are necessary to determine whether mutations in SK channel subtype 2 genes may also drive aldosterone excess in primary hyperaldosteronism. ..
Yang T, He M, Hu C. Regulation of aldosterone production by ion channels: From basal secretion to primary aldosteronism. Biochim Biophys Acta Mol Basis Dis. 2018;1864:871-881 pubmed publisher
..Because potassium and calcium channels are differentially expressed in ZG cells in different species of mammals, the limitations of published studies are also discussed. ..