Research Topics
Genomes and Genes | Hong YanSummaryAffiliation: Fourth Military Medical University Country: China Publications
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Detail Information
Publications
Seminal vesicle metastasis after partial hepatectomy for hepatocellular carcinomaLi Gong
The Helmholtz Sino German Laboratory for Cancer Research, Department of Pathology, Tangdu Hospital, The Fourth Military Medical University, 710038 Xi an, Shaanxi Province, PR China
BMC Cancer 11:111. 2011..The purpose of the present paper was to report a case of metastasis to the seminal vesicle after HCC resection, along with its histological features and immunohistochemical characteristics...
Thioredoxin, thioredoxin reductase, and alpha-crystallin revive inactivated glyceraldehyde 3-phosphate dehydrogenase in human aged and cataract lens extractsHong Yan
Nuffield Laboratory of Ophthalmology, University of Oxford, Walton Street, Oxford, UK
Mol Vis 12:1153-9. 2006....- [The molecular chaperone function of alpha-crystallin in age-related cataract]Hong Yan
Department of Ophthalmology, Tangdu Hospital, The Fourth Military Medical University, Xi an 710038, China
Yan Ke Xue Bao 21:156-60. 2005..To evaluate the molecular chaperone function of alpha-crystallin in age-related cataract... - Revival of glutathione reductase in human cataractous and clear lens extracts by thioredoxin and thioredoxin reductase, in conjunction with alpha-crystallin or thioltransferaseHong Yan
Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi an 710038, China
Curr Eye Res 32:455-63. 2007..These results indicate that both disulfide bond formation and protein unfolding are responsible for GR inactivation... - Carnosine inhibits modifications and decreased molecular chaperone activity of lens alpha-crystallin induced by ribose and fructose 6-phosphateHong Yan
Nuffield Laboratory of Ophthalmology, University of Oxford, Oxford, UK
Mol Vis 12:205-14. 2006..Additionally, we investigated whether carnosine could directly react with a sugar and a sugar phosphate... - [Preventive effect of carnosine on cataract development]Yong Guo
Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi an 710038, China
Yan Ke Xue Bao 22:85-8. 2006..Further study of carnosine on its biological features and the mechanisms of delaying the progression of cataractogenesis may provide a new therapy for preventing cataract... - Effect of carnosine, aminoguanidine, and aspirin drops on the prevention of cataracts in diabetic ratsHong Yan
Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi an, China
Mol Vis 14:2282-91. 2008..To investigate the effect of carnosine (CA), aminoguanidine (AG), and aspirin (ASA) drops, all inhibitors of glycation, on the development of diabetic cataract in rat... - Effects of N-acetylcysteine and glutathione ethyl ester drops on streptozotocin-induced diabetic cataract in ratsShu Zhang
Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi an, China
Mol Vis 14:862-70. 2008..To evaluate the effect of N-acetylcysteine (NAC) and glutathione ethyl ester (GSH-EE) eye drops on the progression of diabetic cataract formation induced by streptozotocin (STZ)... - Effect of a combination of carnosine and aspirin eye drops on streptozotocin -- induced diabetic cataract in ratsQiong Shi
Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi an, China
Mol Vis 15:2129-38. 2009..To investigate the effect of a combination of carnosine and aspirin eye drops on the progression of diabetic cataract formation induced by streptozotocin (STZ)... - Carnosine protects against the inactivation of esterase induced by glycation and a steroidHong Yan
Nuffield Laboratory of Ophthalmology, University of Oxford, Walton St, Oxford OX2 6AW, UK
Biochim Biophys Acta 1741:120-6. 2005..Carnosine decreased the extent of the cross-linking. These results provide further evidence for carnosine's role as an anti-glycation compound. It is also proposed that carnosine may be an anti-steroid agent... - The molecular chaperone, alpha-crystallin, protects against loss of antigenicity and activity of esterase caused by sugars, sugar phosphate and a steroidHong Yan
Nuffield Laboratory of Ophthalmology, University of Oxford, Walton St, Oxford OX2 6AW, UK
Biol Chem 384:1185-94. 2003..The protective effect of alpha-crystallin against loss of antigenicity indicates a novel aspect of its chaperoning function... - Hyperoxia-induced lens damage in rabbit: protective effects of N-acetylcysteinePing Wang
Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi an, China
Mol Vis 15:2945-52. 2009..To investigate the efficacies of different concentrations of N-acetylcysteine (NAC) in preventing hyperoxia-induced lens opacification and changes to biochemical parameters in organ-cultured rabbit lenses... 
Identification of the primary targets of carbamylation in bovine lens proteins by mass spectrometryJie Zhang
Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi an, China
Curr Eye Res 33:963-76. 2008..The aim of this study was to isolate the primary targets of carbamylation in the lens and identify them by mass spectrometry...- Ultraviolet radiation-induced cataract in mice: the effect of age and the potential biochemical mechanismJie Zhang
Department of Ophthalmology, Tangdu Hospital, The Fourth Military Medical University, Xi an, China
Invest Ophthalmol Vis Sci 53:7276-85. 2012..To study the effect of age on the morphologic and biochemical alterations induced by in vivo exposure of ultraviolet radiation (UV)... - Protective effect of aspirin against dexamethasone-induced cataract in cultured rat lensHong Yan
Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China
Ophthalmic Res 38:303-8. 2006..The enzymes, including those that normally eliminate radial oxygen species, could be especially vulnerable. Aspirin significantly inhibits dexamethasone-induced cataract formation by inhibiting inactivation of those enzymes... - [Decreased chaperone activity of alpha-crystallin by carbamylation in vitro]Hong Yan
Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China
Yan Ke Xue Bao 20:264-7. 2004..CONCLUSION: The alpha-crystallin can be modified in vitro by carbamylation through a high-molecular-weight aggregates formation. The loss of its chaperone activity may result from carbamylation-induced aggregation... - [Change of alpha-crystallin acting as molecular chaperone activity with ageing]Hong Yan
Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China
Yan Ke Xue Bao 19:239-43. 2003..CONCLUSION: alpha-Crystallin in the nucleus shows age-related decrease in chaperone function, which may be responsible for cataract formation... - Inhibition of glucocorticoid-induced alteration of vimentin by a glucocorticoid receptor antagonist RU486 in the organ-cultured rat lensGuo Li Xie
Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi an 710038, China
Mol Vis 17:32-40. 2011..Based on a model of steroid-induced cataract from our previous study, the present study focuses on whether changes in vimentin can be induced in vitro through specific GR activation in glucocorticoid-induced cataracts of the rat lens... - Gamma III-crystallin is the primary target of glycation in the bovine lens incubated under physiological conditionsHong Yan
Nuffield Laboratory of Ophthalmology, University of Oxford, Walton Street, Oxford OX2 6AW, UK
Biochem J 374:677-85. 2003..The early glycation of gammaIII-crystallin by glucose and fructose could result in structural alterations, leading to aggregation of crystallin and eventually cataract formation... - Identification of the preferentially targeted proteins by carbamylation during whole lens incubation by using radio-labelled potassium cyanate and mass spectrometryHong Yan
Department of Ophthalmology, Tangdu Hospital, The Fourth Military Medical University, Xi an 710038, Shaanxi Province, China
Int J Ophthalmol 3:104-11. 2010..To attempt to identify the primary targets of carbamylation in bovine lenses incubated under physiological condition... - [Preventive effect of estrogen on cataract development]Jianwei Wang
Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China
Yan Ke Xue Bao 22:20-4. 2006..The research of these effects and its interactions may lead to a better understanding of the protective mechanism of estrogen and also provide a new thought for treatment and prevention of cataract... - Changes of the thiol levels in the corneas of the diabetic rats: effect of carnosine, aspirin and a combination eye dropsQiong Shi
Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi an 710038, Shaanxi Province, China
Int J Ophthalmol 3:211-5. 2010..To investigate the effect of carnosine (Car), aspirin (Asp) and a combination of Car and Asp eye drops on the change of the thiol contents from glutathione (GSH) and protein in the corneas of the diabetic rats... - Preventive measures against sexually transmitted infections among female sex workers in Lanzhou, ChinaWenlong Gao
Department of Epidemiology and Biostatistics, College of Medicine, Xi an Jiaotong University, Xi an, Shaanxi, China
Scand J Infect Dis 44:374-80. 2012..We assessed the effects of preventive practices on sexually transmitted infections (STIs) and reproductive tract infections (RTIs) among female sex workers (FSWs) in Lanzhou, China... - Use of maternal healthcare services in 10 provinces of rural western ChinaXiaoning Liu
Department of Epidemiology and Biostatistics, School of Public Health, Xi an Jiaotong University College of Medicine, Xi an, China
Int J Gynaecol Obstet 114:260-4. 2011..To explore maternal healthcare utilization in rural western China, and to analyze the socioeconomic and demographic determinants associated with use of maternal health services... - Validity of self-reported weight, height and resultant body mass index in Chinese adolescents and factors associated with errors in self-reportsXiaoyan Zhou
From the Department of Epidemiology and Health Statistics, School of Public Health, Xi an Jiaotong University College of Medicine, NO, 76 West Yanta Road, Xi an, China
BMC Public Health 10:190. 2010..This study aims to examine the accuracy of self-reported weight, height, and resultant BMI values in Chinese adolescents, and of the adolescents' subsequent classification into overweight categories... - [Pathogenesis and prevention strategies of indirect injured cataract formation after vitrectomy]Xiaocui Liu
Department of Ophthalmology, Tangdu Hospital, The 4th Military Medical University, Xi an 710038, China
Yan Ke Xue Bao 23:252-6. 2007..Therefore, the measure of decreasing oxygen concentration and the treatment of Zinc-desferrioxamine may reduce the incidence of cataract, which provides a new way for the prevention and treatment of cataract after vitrectomy... - CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytesLie Gang Liu
Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China
World J Gastroenterol 11:4530-5. 2005.... - Effects of melatonin in age-related macular degenerationChangxian Yi
Department of Fundus Diseases, Zhongshan Ophthalmic Center, Sun Yat Sen University, 510060 Guangzhou, China
Ann N Y Acad Sci 1057:384-92. 2005..The majority had reduced pathologic macular changes. We conclude that the daily use of 3 mg melatonin seems to protect the retina and to delay macular degeneration. No significant side effects were observed...