Guodong Gao

Summary

Affiliation: Fourth Military Medical University
Country: China

Publications

  1. pmc Progress on stem cell research towards the treatment of Parkinson's disease
    Stuart A J Gibson
    Regenerative Medicine Institute, School of Medicine, National University of Ireland Galway, Newcastle Road, Galway, Ireland
    Stem Cell Res Ther 3:11. 2012
  2. pmc Single-wall carbon nanohorns inhibited activation of microglia induced by lipopolysaccharide through blocking of Sirt3
    Lihong Li
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, 710038, Xi an, China
    Nanoscale Res Lett 8:100. 2013
  3. pmc Reduced expression of SMAD4 in gliomas correlates with progression and survival of patients
    Shi Ming He
    Department of Neurosurgery, Institute for functional neurosurgery P L A, Tangdu Hospital, Fourth Military Medical University, Xi an, 710038, PR China
    J Exp Clin Cancer Res 30:70. 2011
  4. ncbi Clinical study for alleviating opiate drug psychological dependence by a method of ablating the nucleus accumbens with stereotactic surgery
    Guodong Gao
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xian, China
    Stereotact Funct Neurosurg 81:96-104. 2003
  5. pmc Effects of bilateral deep brain stimulation of the subthalamic nucleus on olfactory function in Parkinson's disease patients
    Xiaodong Guo
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Institute for Functional Neurosurgery of PLA, Xi an, China
    Stereotact Funct Neurosurg 86:237-44. 2008
  6. doi Forkhead-box A1 transcription factor is a novel adverse prognosis marker in human glioma
    Liang Wang
    Department of Neurosurgery, Tangdu Hospital, 569 Xinsi Road, Baqiao District, Xi an City 710038, China
    J Clin Neurosci 20:654-8. 2013
  7. doi Downregulation of chromatin remodeling factor CHD5 is associated with a poor prognosis in human glioma
    Liang Wang
    Department of Neurosurgery, Tangdu Hospital, No 569, Xinsi Road, Baqiao District, Xi an City 710038, China
    J Clin Neurosci 20:958-63. 2013
  8. doi Overexpression of CCL20 and its receptor CCR6 predicts poor clinical prognosis in human gliomas
    Liang Wang
    Department of Neurosurgery, Tangdu Hospital, No 569, Xinsi Road, Baqiao District, Xi an City, 710038, China
    Med Oncol 29:3491-7. 2012
  9. pmc RTEL1 tagging SNPs and haplotypes were associated with glioma development
    Gang Li
    Department of Neurosurgery, Tangdu Hospital, The Fourth Military Medical University, Xi an, 710038, China
    Diagn Pathol 8:83. 2013
  10. pmc Occipital anaplastic oligodendroglioma with multiple organ metastases after a short clinical course: a case report and literature review
    Gang Li
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi an 710038, P, R China
    Diagn Pathol 9:17. 2014

Collaborators

Detail Information

Publications29

  1. pmc Progress on stem cell research towards the treatment of Parkinson's disease
    Stuart A J Gibson
    Regenerative Medicine Institute, School of Medicine, National University of Ireland Galway, Newcastle Road, Galway, Ireland
    Stem Cell Res Ther 3:11. 2012
    ..A combined approach of drugs, cell replacement, and gene therapy to stop disease progression and to improve treatment may soon be within our reach...
  2. pmc Single-wall carbon nanohorns inhibited activation of microglia induced by lipopolysaccharide through blocking of Sirt3
    Lihong Li
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, 710038, Xi an, China
    Nanoscale Res Lett 8:100. 2013
    ..The role of SWNHs on mice microglia was implicating Sirt3 and energy metabolism associated with it...
  3. pmc Reduced expression of SMAD4 in gliomas correlates with progression and survival of patients
    Shi Ming He
    Department of Neurosurgery, Institute for functional neurosurgery P L A, Tangdu Hospital, Fourth Military Medical University, Xi an, 710038, PR China
    J Exp Clin Cancer Res 30:70. 2011
    ..To examine the expression of SMAD4 at gene and protein levels in glioma samples with different WHO grades and its association with survival...
  4. ncbi Clinical study for alleviating opiate drug psychological dependence by a method of ablating the nucleus accumbens with stereotactic surgery
    Guodong Gao
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xian, China
    Stereotact Funct Neurosurg 81:96-104. 2003
    ..No particular complications occurred. The operation is safe and feasible. The mean follow-up time in this study was 15 months. The effectiveness was satisfactory. The relapse rate of drug addicts after detoxification was clearly reduced...
  5. pmc Effects of bilateral deep brain stimulation of the subthalamic nucleus on olfactory function in Parkinson's disease patients
    Xiaodong Guo
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Institute for Functional Neurosurgery of PLA, Xi an, China
    Stereotact Funct Neurosurg 86:237-44. 2008
    ..The goal of the present study was to evaluate the effects of bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) on olfaction in patients with Parkinson's disease (PD)...
  6. doi Forkhead-box A1 transcription factor is a novel adverse prognosis marker in human glioma
    Liang Wang
    Department of Neurosurgery, Tangdu Hospital, 569 Xinsi Road, Baqiao District, Xi an City 710038, China
    J Clin Neurosci 20:654-8. 2013
    ....
  7. doi Downregulation of chromatin remodeling factor CHD5 is associated with a poor prognosis in human glioma
    Liang Wang
    Department of Neurosurgery, Tangdu Hospital, No 569, Xinsi Road, Baqiao District, Xi an City 710038, China
    J Clin Neurosci 20:958-63. 2013
    ..01). In conclusion, these data offer convincing evidence for the first time that CHD5 might act as a tumor suppressor in glioma, may act as a regulator of aggressive development, and is a candidate prognostic marker for this malignancy...
  8. doi Overexpression of CCL20 and its receptor CCR6 predicts poor clinical prognosis in human gliomas
    Liang Wang
    Department of Neurosurgery, Tangdu Hospital, No 569, Xinsi Road, Baqiao District, Xi an City, 710038, China
    Med Oncol 29:3491-7. 2012
    ..The up-regulation of CCL20 and CCR6 might be closely associated with poor clinical outcome of patients with gliomas...
  9. pmc RTEL1 tagging SNPs and haplotypes were associated with glioma development
    Gang Li
    Department of Neurosurgery, Tangdu Hospital, The Fourth Military Medical University, Xi an, 710038, China
    Diagn Pathol 8:83. 2013
    ..And it might be used to evaluate the glioma development risks to screen the above RTEL1 tagging SNPs and haplotypes...
  10. pmc Occipital anaplastic oligodendroglioma with multiple organ metastases after a short clinical course: a case report and literature review
    Gang Li
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi an 710038, P, R China
    Diagn Pathol 9:17. 2014
    ..It is generally believed that malignant gliomas never metastasize outside the central nervous system (CNS). However, the notion that oligodendrogliomas (OGDs) cells cannot spread outside CNS is being challenged...
  11. pmc Correlation of microRNA-372 upregulation with poor prognosis in human glioma
    Gang Li
    Department of Neurosurgery, Tangdu Hospital, The Fourth Military Medical University, No 569, Xinsi Road, Xi an 710038, China
    Diagn Pathol 8:1. 2013
    ....
  12. doi Long-term changes in the personality and psychopathological profile of opiate addicts after nucleus accumbens ablative surgery are associated with treatment outcome
    Shunnan Ge
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi an, China
    Stereotact Funct Neurosurg 91:30-44. 2013
    ..To investigate the long-term outcome and changes of the personality and psychopathological profile of opiate addicts after bilateral stereotactic nucleus accumbens (NAc) ablative surgery...
  13. pmc CD24 expression as a marker for predicting clinical outcome in human gliomas
    Jianping Deng
    Department of Neurosurgery, Institute for Functional Neurosurgery PLA, Tangdu Hospital, Fourth Military Medical University, Baqiao District, Xi an, China
    J Biomed Biotechnol 2012:517172. 2012
    ..Our data provides convincing evidence for the first time that the overexpression of CD24 at gene and protein levels is correlated with advanced clinicopathological parameters and poor prognosis in patients with glioma...
  14. pmc High frequency of the X-chromosome inactivation in young female patients with high-grade glioma
    Gang Li
    Department of Neurosurgery, Tangdu Hospital, The Fourth Military Medical University, 710038 Xi an, China che
    Diagn Pathol 8:101. 2013
    ..As skewed XCI has been linked to development of some solid tumors, including ovarian, breast, and pulmonary and esophageal carcinomas, it is challenging to elucidate the relation of skewed XCI to high-grade gliomas development...
  15. doi Function and phenotype of microglia are determined by toll-like receptor 2/toll-like receptor 4 activation sequence
    Weixin Li
    Neurosurgical Department, Tangdu Hospital, Fourth Military Medical University, Xi an, People s Republic of China
    DNA Cell Biol 28:493-9. 2009
    ..Expression of costimulatory molecules CD80/CD86 increases with TLR2 or TLR4 activation sequences. Our results reveal that TLR2/TLR4 activation may determine disease pathogenesis and prognosis...
  16. pmc Skewed X-chromosome inactivation in patients with esophageal carcinoma
    Gang Li
    Department of Neurosurgery, Tangdu Hospital, The Fourth Military Medical University, Xi an, China
    Diagn Pathol 8:55. 2013
    ..217). SXCI also occurs in apparently healthy Chinese females, and is associated with age. It may be considered as a predisposing factor for the early development of esophageal carcinoma...
  17. doi Matrix metalloproteinase-9 expression is increased in astrocytic glioma and associated with prognosis of patients
    Jipei Zhao
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, No 569, Xinsi Road, Xi an, PR China
    Jpn J Clin Oncol 42:1060-5. 2012
    ..This study was aimed at investigating the expression of matrix metalloproteinase-9 in astrocytic glioma samples and its association with clinicopathological characteristics as well as survival of patients...
  18. pmc Elevated expression of chloride intracellular channel 1 is correlated with poor prognosis in human gliomas
    Liang Wang
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University of PLA, NO, 569, Xinsi Road, Baqiao District, Xi an City, 710038, China
    J Exp Clin Cancer Res 31:44. 2012
    ..However, its roles in human gliomas are still unclear. The aim of this study was to investigate the clinicopathological significance and prognostic value of CLIC1 expression in human gliomas...
  19. ncbi Stratifin expression is a novel prognostic factor in human gliomas
    Jianping Deng
    Department of Neurosurgery, Institute for functional neurosurgery P L A, Tangdu Hospital, Fourth Military Medical University, 1, Xinsi Road, Baqiao District, Xi an 710038, PR China
    Pathol Res Pract 207:674-9. 2011
    ..Its expression level is correlated with the clinicopathological parameters and prognosis in patients with gliomas. Pending validation targeting, Stratifin might also be a novel opportunity to improve the therapy of this tumor...
  20. doi Treatment of intractable anorexia nervosa with inactivation of the nucleus accumbens using stereotactic surgery
    Jing Wang
    Department of Neurosurgery and Institute for Functional Brain Disorders, Tangdu Hospital, Fourth Military Medical University, Xi an, PR China
    Stereotact Funct Neurosurg 91:364-72. 2013
    ..For 30% of anorexia nervosa (AN) patients, conventional treatments are unsuccessful; this is termed intractable AN...
  21. doi Protective effect of HIF-1α against hippocampal apoptosis and cognitive dysfunction in an experimental rat model of subarachnoid hemorrhage
    Yushu Dong
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi an 710032, China
    Brain Res 1517:114-21. 2013
    ..These results indicate that hippocampal apoptosis increased and cognitive function deteriorated when HIF-1α was inhibited, suggesting that HIF-1α has a neuroprotective effect in SAH and may represent an effective therapeutic target...
  22. doi Notch1 is an independent prognostic factor for patients with glioma
    Jiang Li
    Department of Neurosurgery, Tangdu Hospital, The Forth Military Medical University, Xi an, China
    J Surg Oncol 103:813-7. 2011
    ..Notch signaling plays a complex role in human malignancy. It can affect cell proliferation, differentiation, and apoptosis either positively or negatively, depending on cell type...
  23. doi Long-term effects of bilateral deep brain stimulation of the subthalamic nucleus on depression in patients with Parkinson's disease
    Xuelian Wang
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi an, Shaanxi Province, China
    Parkinsonism Relat Disord 15:587-91. 2009
    ..To study the long-term effects of deep brain stimulation (DBS) of the bilateral subthalamic nucleus (STN) on depression in patients with Parkinson's disease (PD) and to discuss the mechanism...
  24. ncbi Inhibition of basigin expression in glioblastoma cell line via antisense RNA reduces tumor cell invasion and angiogenesis
    Qinchuan Liang
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi an City, China
    Cancer Biol Ther 4:759-62. 2005
    ..Basigin/CD147 may be used as a potential target of drugs for anti-invasion and metastasis of human glioblastoma cells...
  25. doi Dopamine depletion increases the power and coherence of high-voltage spindles in the globus pallidus and motor cortex of freely moving rats
    Shunnan Ge
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi an 710038, People s Republic of China
    Brain Res 1465:66-79. 2012
    ....
  26. doi A hypermotor seizure with a focal orbital frontal lesion originating in the insula: a case report
    Hua Zhang
    Department of Neurosurgery, Tangdu Hospital, The Fourth Military Medical University, Shaanxi Province, China
    Epilepsy Res 82:211-4. 2008
    ..The seizure onset zone was localized in the right anterior insula by intracranial recording. A resection of the right anterior insula and a partial disconnection of the frontal lobe were performed, rendering the patient seizure-free...
  27. pmc Oxidation of survival factor MEF2D in neuronal death and Parkinson's disease
    Li Gao
    1 Department of Neurosurgery, Tangdu Hospital, The Fourth Military Medical University, Xi an, China
    Antioxid Redox Signal 20:2936-48. 2014
    ..Both genetic factors and neurotoxins associated with PD impair MEF2D function in vitro and in animal models of PD. We investigated whether distinct stress conditions target MEF2D via converging mechanisms...
  28. pmc Inhibition of STAT3 Reduces Astrocytoma Cell Invasion and Constitutive Activation of STAT3 Predicts Poor Prognosis in Human Astrocytoma
    Qinchuan Liang
    Department of Pediatric Neurosurgery, Xin Hua Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, People s Republic of China Department of Neurosurgery, Tang Du Hospital, Institution for Functional Neurosurgery of P L A, Fourth Military Medical University, Xi an, Shannxi Province, People s Republic of China
    PLoS ONE 8:e84723. 2013
    ..Therefore, STAT3 may provide a potential target for molecular therapy in human astrocytoma, and pSTAT3(Tyr705)could be an important biomarker for astrocytoma prognosis. ..
  29. ncbi Local Nogo-66 administration reduces neuropathic pain after sciatic nerve transection in rat
    Lihong Li
    Department of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, China
    Neurosci Lett 424:145-8. 2007
    ..Taken together, the results of our present study suggest that Nogo-66 may be utilized to decrease the neuropathic pain after periphery nerve injury...