Zhou Fei

Summary

Affiliation: Fourth Military Medical University
Country: China

Publications

  1. pmc Relation of LAT1/4F2hc expression with pathological grade, proliferation and angiogenesis in human gliomas
    Zhen Haining
    Department of Neurological Surgery, Faculty of Medicine, Kagawa University, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa, 761 0793, Japan
    BMC Clin Pathol 12:4. 2012
  2. ncbi request reprint Removal of large benign cephalonasal tumours by transbasal surgery combined with endonasal endoscopic sinus surgery and neuronavigation
    Zhou Fei
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xian, PR China
    J Craniomaxillofac Surg 35:30-4. 2007
  3. ncbi request reprint Metabotropic glutamate receptor antagonists and agonists: potential neuroprotectors in diffuse brain injury
    Zhou Fei
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, P R China
    J Clin Neurosci 13:1023-7. 2006
  4. ncbi request reprint Secondary insults and outcomes in patients with hypertensive basal ganglia hemorrhage
    Z Fei
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, P R China
    Acta Neurochir Suppl 95:265-7. 2005
  5. pmc Posttraumatic secondary brain insults exacerbates neuronal injury by altering metabotropic glutamate receptors
    Zhou Fei
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, 710032, PR China
    BMC Neurosci 8:96. 2007
  6. ncbi request reprint Altered expression patterns of metabotropic glutamate receptors in diffuse brain injury
    Zhou Fei
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, PR China
    Neurosci Lett 380:280-3. 2005
  7. ncbi request reprint The expression and changes of heat shock protein 70, MDA and haemorheology in rat cortex after diffuse axonal injury with secondary insults
    F Zhou
    Department of Neurosurgery, Xijing Hospital, Xi an, PRChina
    J Clin Neurosci 8:250-2. 2001
  8. ncbi request reprint Changes of mGluR4 and the effects of its specific agonist L-AP4 in a rodent model of diffuse brain injury
    Fei Zhou
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, PR China
    J Clin Neurosci 10:684-8. 2003
  9. ncbi request reprint Changes of metabotropic glutamate receptor subtype 1a in diffuse brain injury with secondary brain insults and the effects of 2-methyl-4-carboxyphenylglycine
    Zhou Fei
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xian 710033, China
    Chin J Traumatol 6:270-4. 2003
  10. doi request reprint Hemorrhagic pituitary macroadenoma: characteristics, endoscopic endonasal transsphenoidal surgery, and outcomes
    Xiang Zhang
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi Province, People s Republic of China
    Ann Surg Oncol 18:246-52. 2011

Collaborators

  • Xiang Zhang
  • Yan Qu
  • Lei Zhang
  • Tao Chen
  • Wei ping Liu
  • Wei Zhang
  • Xia Li
  • Wei Lin
  • Luo an Fu
  • Xiao Sheng He
  • Bing Li
  • Hong Min Bai
  • Kai Wang
  • Jian ning Zhang
  • Yang Yang
  • Peng Wang
  • Yuan Wang
  • Peng Luo
  • Yongbo Zhao
  • Xituan Ji
  • Xiaodong Chao
  • Xi tuan Ji
  • Xiaofan Jiang
  • Yang Liu
  • Hai ning Zhen
  • San zhong Li
  • Wei Rao
  • Haoxiang Xu
  • Qianfa Long
  • Yihui Ma
  • Xing gang Mao
  • Guang Cheng
  • Mingming Zhao
  • Shi Jie Hu
  • Dakuan Gao
  • Waisang Poon
  • Geng Guo
  • Xiaoliang Yang
  • Weidong Cao
  • Shu hui Dai
  • Wei dong Cao
  • Yong Bo Zhao
  • Zao bin Liu
  • Gang Huang
  • Le Niu
  • Yalong He
  • Yue Fei Zhou
  • Dong Sheng Zhao
  • Juan Li
  • Bo Lin Liu
  • Da kuan Gao
  • Jun Zhong
  • Kai Huo
  • Ning Su
  • Zhen Haining
  • Sanzhong Li
  • Y H Ma
  • Qindong Guo
  • Xiao Fan Jiang
  • Rui Han
  • F Zhou
  • Jian Liu
  • Xiao an Wang
  • Qian fa Long
  • Keliang Xie
  • Fei Fei
  • Jie Zhou
  • Xiao dong Chao
  • Jun Zhou
  • Xiao Yan Xue
  • Tong Tao Yang
  • Wei Dong Huang
  • Fei Zhou
  • Shao Jun Song
  • Jun Liu
  • Jing Zhao
  • Xi Cai Yi
  • Chen Cheng Ji
  • Na Qin
  • Dong Mei Wang
  • Ji dong Sun
  • Yi Yang Hu
  • Feng Feng
  • Shuhui Dai
  • Hao Hui
  • Dong Jia
  • Jin mao Li
  • Yun Zhang
  • Tao Zhang
  • Haifeng Tang

Detail Information

Publications83

  1. pmc Relation of LAT1/4F2hc expression with pathological grade, proliferation and angiogenesis in human gliomas
    Zhen Haining
    Department of Neurological Surgery, Faculty of Medicine, Kagawa University, 1750 1 Ikenobe, Miki cho, Kita gun, Kagawa, 761 0793, Japan
    BMC Clin Pathol 12:4. 2012
    ..abstract:..
  2. ncbi request reprint Removal of large benign cephalonasal tumours by transbasal surgery combined with endonasal endoscopic sinus surgery and neuronavigation
    Zhou Fei
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xian, PR China
    J Craniomaxillofac Surg 35:30-4. 2007
    ..A retrospective study has been made of the transbasal and endonasal endoscopic sinus surgery of 29 cases with cephalonasal tumours treated in this hospital since 2001 in order to evaluate their clinical outcome...
  3. ncbi request reprint Metabotropic glutamate receptor antagonists and agonists: potential neuroprotectors in diffuse brain injury
    Zhou Fei
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, P R China
    J Clin Neurosci 13:1023-7. 2006
    ..This suggests that icv injection of the mGluR group I antagonist MCPG or the mGluR group II agonist DCG-IV may exert neuroprotective effects in the early stage after DBI...
  4. ncbi request reprint Secondary insults and outcomes in patients with hypertensive basal ganglia hemorrhage
    Z Fei
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, P R China
    Acta Neurochir Suppl 95:265-7. 2005
    ..It is concluded that the high incident rate of secondary insults in HICH patients influences outcome. Ultra-early surgery may also contribute to improved quality of survival...
  5. pmc Posttraumatic secondary brain insults exacerbates neuronal injury by altering metabotropic glutamate receptors
    Zhou Fei
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, 710032, PR China
    BMC Neurosci 8:96. 2007
    ....
  6. ncbi request reprint Altered expression patterns of metabotropic glutamate receptors in diffuse brain injury
    Zhou Fei
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, PR China
    Neurosci Lett 380:280-3. 2005
    ..It may provide new insight for the development of new pharmaceuticals in the treatment of DBI...
  7. ncbi request reprint The expression and changes of heat shock protein 70, MDA and haemorheology in rat cortex after diffuse axonal injury with secondary insults
    F Zhou
    Department of Neurosurgery, Xijing Hospital, Xi an, PRChina
    J Clin Neurosci 8:250-2. 2001
    ..Free radicals and haemorheological changes play an important role in the aggravation of brain damage and HSP70 expression upregulation...
  8. ncbi request reprint Changes of mGluR4 and the effects of its specific agonist L-AP4 in a rodent model of diffuse brain injury
    Fei Zhou
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, PR China
    J Clin Neurosci 10:684-8. 2003
    ..Therefore, the mGluR4 specific agonists might exert neuroprotective effects after DBI. The focus of this study is to examine the changes of expression of mGluR4 after DBI and the role of its specific agonist L-AP4 in vivo...
  9. ncbi request reprint Changes of metabotropic glutamate receptor subtype 1a in diffuse brain injury with secondary brain insults and the effects of 2-methyl-4-carboxyphenylglycine
    Zhou Fei
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xian 710033, China
    Chin J Traumatol 6:270-4. 2003
    ..To observe the changes of metabotropic glutamate receptor 1a in rat brain in a rodent model of diffuse head injury with secondary insults and the effects of 2-methyl-4-carboxyphenylglycine (MCPG)...
  10. doi request reprint Hemorrhagic pituitary macroadenoma: characteristics, endoscopic endonasal transsphenoidal surgery, and outcomes
    Xiang Zhang
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi Province, People s Republic of China
    Ann Surg Oncol 18:246-52. 2011
    ..This study aims to assess the effect of endoscopic endonasal transsphenoidal surgery (EETSS) of hemorrhagic pituitary macroadenoma (HPMA)...
  11. doi request reprint Blockade of SOCE protects HT22 cells from hydrogen peroxide-induced apoptosis
    Wei Rao
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, PR China
    Biochem Biophys Res Commun 441:351-6. 2013
    ..These findings suggest that SOCE inhibition exhibited neuroprotection against oxidative stress induced by H2O2 and SOCE might be a useful therapeutic target in neurobiological disorders. ..
  12. doi request reprint Iduna protects HT22 cells from hydrogen peroxide-induced oxidative stress through interfering poly(ADP-ribose) polymerase-1-induced cell death (parthanatos)
    Haoxiang Xu
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, People s Republic of China
    Cell Signal 25:1018-26. 2013
    ....
  13. ncbi request reprint Emergency transsphenoidal surgery for hemorrhagic pituitary adenomas
    Xiang Zhang
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Fourth Military Medical University, Xi an, PR China
    Surg Oncol 16:115-20. 2007
    ..With emergency surgical treatment, most patients with HPA could have quick improvement of symptoms, especially for altered consciousness and visual acuity or visual fields impairments...
  14. doi request reprint Downregulation of postsynaptic density-95-interacting regulator of spine morphogenesis reduces glutamate-induced excitotoxicity by differentially regulating glutamate receptors in rat cortical neurons
    Peng Luo
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, China
    FEBS J 280:6114-27. 2013
    ..Therefore, Preso might be a potential pharmacological target for preventing and treating neurological diseases...
  15. doi request reprint Protective effects of mGluR5 positive modulators against traumatic neuronal injury through PKC-dependent activation of MEK/ERK pathway
    Tao Chen
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xijing Hospital, Fourth Military Medical University, Xi an 710032, Shaanxi, China
    Neurochem Res 37:983-90. 2012
    ..These results may have important implications for the development of mGluR5 modulators to treat TBI...
  16. doi request reprint Down-regulation of Homer1b/c attenuates glutamate-mediated excitotoxicity through endoplasmic reticulum and mitochondria pathways in rat cortical neurons
    Tao Chen
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi, China
    Free Radic Biol Med 52:208-17. 2012
    ....
  17. pmc Resveratrol represses YKL-40 expression in human glioma U87 cells
    Wei Zhang
    Department of Neurosurgery, Xijing Hospital, The Fourth Military Medical University, 127 West Changle Road, Xi an, Shaanxi Province, 710032, People s Republic of China
    BMC Cancer 10:593. 2010
    ..Hence, YKL-40 could be an attractive target in the design of anti-cancer therapies...
  18. doi request reprint Endoscopic endonasal transsphenoidal surgery for invasive pituitary adenoma
    Xiang Zhang
    Department of Neurosurgery, Xijing Hospital of the Fourth Military Medical University, No 127 Chang le Western Road, Xi n 710032, Shaanxi Province, People s Republic of China
    J Clin Neurosci 15:241-5. 2008
    ....
  19. ncbi request reprint [Endoscopic endonasal transsphenoidal approach for pituitary adenomas]
    Xiang Zhang
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience Fourth Military Medical University, Xi an 710032, China
    Zhonghua Wai Ke Za Zhi 44:1551-4. 2006
    ..To assess the clinical curative effect of the endonasal transsphenoidal approach for removing pituitary adenoma (PA) under neuroendoscope-assisted...
  20. doi request reprint Protective effect of Homer 1a on tumor necrosis factor-α with cycloheximide-induced apoptosis is mediated by mitogen-activated protein kinase pathways
    Peng Luo
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 15 Changle xi Road, Xian, 710032, PR China
    Apoptosis 17:975-88. 2012
    ..These findings suggest that Homer 1a plays an important role in the prevention of apoptotic cell death and contributes to distinct regulatory effects of MAPK pathways on apoptotic cell death...
  21. ncbi request reprint Maintenance of critical properties of brain tumor stem-like cells after cryopreservation
    Xing gang Mao
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi Province 710032, People s Republic of China
    Cell Mol Neurobiol 30:775-86. 2010
    ....
  22. doi request reprint Up-regulation of EphA2 and down-regulation of EphrinA1 are associated with the aggressive phenotype and poor prognosis of malignant glioma
    Xia Li
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, 710032, Shaan Xi Province, People s Republic of China
    Tumour Biol 31:477-88. 2010
    ..EphA2 suppression partially reversed the aggressive phenotypes of malignant gliomas, possibly through up-regulating EphrinA1 expression, which may help explain how EphA2 modulates the malignant progression of gliomas...
  23. pmc Protective effects of SKF-96365, a non-specific inhibitor of SOCE, against MPP+-induced cytotoxicity in PC12 cells: potential role of Homer1
    Tao Chen
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi, China
    PLoS ONE 8:e55601. 2013
    ....
  24. doi request reprint VEGF upregulates Homer 1a gene expression via the mitogen-activated protein kinase cascade in cultured cortex neurons
    Yuan Wang
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, China
    Neurosci Lett 515:44-9. 2012
    ..These results demonstrate that MAPK is a key mediator that links distinct extracellular VEGF stimuli to the transcriptional activation of Homer 1a mRNA...
  25. doi request reprint The microsurgical treatment of cranio-orbital tumors assisted by intraoperative electrophysiologic monitoring and neuronavigation
    Dakuan Gao
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi Province 710032, PR China
    Clin Neurol Neurosurg 114:891-6. 2012
    ..Intraoperative electrophysiologic monitoring and neuronavigational system have been widely used in microneurosurgery, but their effects during microsurgical treatment of cranio-orbital tumors warrant further investigation...
  26. doi request reprint Protective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress
    Xituan Ji
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xiing Hospital, Fourth Military Medical University, Xi an, Shaanxi Province, PR China
    J Surg Res 178:e9-16. 2012
    ..In contrast to H(2), hydrogen-rich saline (HS) may be more suitable for clinical application. The present study was designed to investigate whether HS has a protective effect against TBI via reducing oxidative stress in rats...
  27. doi request reprint Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo
    Yongbo Zhao
    Institute of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 17 Changlexi Street, Xi an, Shaanxi Province 710032, People s Republic of China
    Exp Neurol 237:489-98. 2012
    ..The interactions between SIRT1 and MAPK/ERK pathway regulate neuronal apoptosis induced by mechanical trauma injury in vitro and in vivo...
  28. doi request reprint Beneficial effects of hydrogen gas in a rat model of traumatic brain injury via reducing oxidative stress
    Xituan Ji
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xiing Hospital, Fourth Military Medical University, Xi an 710032, Shaanxi Province, PR China
    Brain Res 1354:196-205. 2010
    ..The present study supports that H(2) inhalation may be a more effective therapeutic strategy for patients with TBI...
  29. ncbi request reprint Short hairpin RNA targeting survivin inhibits growth and angiogenesis of glioma U251 cells
    Hai ning Zhen
    Institute of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an 710033, P R China
    Int J Oncol 31:1111-7. 2007
    ....
  30. ncbi request reprint Neuroprotective effect of osthole on MPP+-induced cytotoxicity in PC12 cells via inhibition of mitochondrial dysfunction and ROS production
    Wen Bo Liu
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xiing Hospital, Fourth Military Medical University, Xi an 710032, China
    Neurochem Int 57:206-15. 2010
    ....
  31. doi request reprint MicroRNA-34a induces apoptosis in the human glioma cell line, A172, through enhanced ROS production and NOX2 expression
    San zhong Li
    Department of Neurosurgery, Xi Jing Hospital, Fourth Military Medical University, Xi an 710032, China
    Biochem Biophys Res Commun 444:6-12. 2014
    ..Recent research supports key roles of miRNA in the formation and development of human glioma...
  32. doi request reprint The risk of osteopenia in premenopausal women with various sellar tumors
    Yongbo Zhao
    Institute of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi Province, China
    Gynecol Endocrinol 28:945-8. 2012
    ..The aim of the present study is to assess the bone mass alteration in patients with various sellar tumors and further to investigate the risk factors of bone mass alteration...
  33. doi request reprint Protective effect of Homer 1a against hydrogen peroxide-induced oxidative stress in PC12 cells
    Peng Luo
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, PR China
    Free Radic Res 46:766-76. 2012
    ....
  34. doi request reprint VEGF protects rat cortical neurons from mechanical trauma injury induced apoptosis via the MEK/ERK pathway
    Yihui Ma
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, China
    Brain Res Bull 86:441-6. 2011
    ..Therefore, the present study supports the notion that MEK/ERK pathway is involved in VEGF mediated neuroprotection against mechanical trauma injury...
  35. doi request reprint Protective effects of hydrogen sulfide in a rat model of traumatic brain injury via activation of mitochondrial adenosine triphosphate-sensitive potassium channels and reduction of oxidative stress
    Xiaofan Jiang
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xiing Hospital, Fourth Military Medical University, Xi an, Shaanxi Province, People s Republic of China
    J Surg Res 184:e27-35. 2013
    ..We designed the present study to investigate the effects of exogenous H2S in a rat model of traumatic brain injury (TBI) and the mechanism(s) that underlie this effect...
  36. doi request reprint Osthole attenuates spinal cord ischemia-reperfusion injury through mitochondrial biogenesis-independent inhibition of mitochondrial dysfunction in rats
    Yue Fei Zhou
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi, China
    J Surg Res 185:805-14. 2013
    ..cusson, has been shown to exert spectrum of pharmacologic activities. The aim of this study was to investigate the potential neuroprotective effects of osthole against spinal cord ischemia-reperfusion injury in rats...
  37. doi request reprint Targeting 14-3-3 protein, difopein induces apoptosis of human glioma cells and suppresses tumor growth in mice
    Weidong Cao
    Institute of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Changle Western Road 17, 710032 Xi an, Shaanxi Province, People s Republic of China
    Apoptosis 15:230-41. 2010
    ..This work not only reveals a critical role of 14-3-3 in apoptosis suppression in glioma cells, but also identifies and validates 14-3-3 as a potential molecular target for anticancer therapeutic development...
  38. ncbi request reprint Resveratrol inhibits cell growth and induces apoptosis of rat C6 glioma cells
    Wei Zhang
    Department of Neurosurgery, Neurosurgical Institute of Chinese PLA, Xijing Hospital, Fourth Military Medical University, No 127 West Chang le Road, Xi an, 710032, Shaanxi Province, People s Republic of China
    J Neurooncol 81:231-40. 2007
    ..These results suggest that Res has significant apoptosis-inducing effect on C6 glioma cells other than normal fibroblast 3T3 cells in vitro and caspase-3 may act as a potential mediator in the process...
  39. pmc The selective mGluR5 agonist CHPG protects against traumatic brain injury in vitro and in vivo via ERK and Akt pathway
    Tao Chen
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xijing Hospital, Fourth Military Medical University, Xi an, Shannxi 710032, PR China
    Int J Mol Med 29:630-6. 2012
    ..Thus, potentiating mGluR5 activity with selective agonists such as CHPG may be useful for the treatment of traumatic brain injury...
  40. ncbi request reprint Association between YKL-40 and adult primary astrocytoma
    Wei Zhang
    Department of Neurosurgery, Xijing Hospital, The Fourth Military Medical University, Xi an, Shaanxi Province, People s Republic of China
    Cancer 116:2688-97. 2010
    ....
  41. ncbi request reprint Survivin expression and its relation with proliferation, apoptosis, and angiogenesis in brain gliomas
    Hai ning Zhen
    Institute of Neurosurgery, Xijing Hospital, The Fourth Military Medical University, Xi an, The People s Republic of China
    Cancer 104:2775-83. 2005
    ....
  42. doi request reprint The expression of hepatoma-derived growth factor in primary central nervous system lymphoma and its correlation with angiogenesis, proliferation and clinical outcome
    San zhong Li
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Changle West Road 169, Xi an, 710032, China
    Med Oncol 30:622. 2013
    ..Multivariate analysis revealed that postoperative adjuvant chemotherapy and high expression of HDGF was independent prognostic indicator of patient survival...
  43. ncbi request reprint Activation of mGluR5 Attenuates NMDA-Induced Neurotoxicity through Disruption of the NMDAR-PSD-95 Complex and Preservation of Mitochondrial Function in Differentiated PC12 Cells
    Shu hui Dai
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xijing Hospital, Fourth Military Medical University, Xi an 710032, China
    Int J Mol Sci 15:10892-907. 2014
    ....
  44. doi request reprint Posterior reduction and instrumentation with rod-screw construct for atlanto-axial dislocation: a single institutional study with 21 consecutive cases
    Xi tuan Ji
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, PR China
    Clin Neurol Neurosurg 115:1433-9. 2013
    ..Atlanto-axial dislocation is one of the leading causes for occipito-cervical instability. This study aimed for investigating the clinical outcome of rod-screw construct rather than traditional posterior wiring for atlanto-axial dislocation...
  45. pmc Saponin 1 induces apoptosis and suppresses NF-κB-mediated survival signaling in glioblastoma multiforme (GBM)
    Juan Li
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Fourth Military Medical University, Xi an, China Faculty of Biomedical Engineering, Fourth Military Medical University, Xi an, China
    PLoS ONE 8:e81258. 2013
    ....
  46. doi request reprint Basic fibroblast growth factor increases the transplantation‑mediated therapeutic effect of bone mesenchymal stem cells following traumatic brain injury
    Yang Liu
    Department of Neurosurgery, The Third Hospital of Mianyang, Mianyang, Sichuan 621000, P R China
    Mol Med Rep 9:333-9. 2014
    ..In conclusion, exogenous bFGF functions as a booster of the transplantation‑mediated therapeutic effect of BMSCs following TBI. ..
  47. doi request reprint Expression of candidate plasticity-related gene 15 is increased following traumatic brain injury
    Yalong He
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, China
    Neurol Res 35:174-80. 2013
    ....
  48. doi request reprint Over-expression of Mash1 improves the GABAergic differentiation of bone marrow mesenchymal stem cells in vitro
    Kai Wang
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Fourth Military Medical University, No 17 Chang le West Road, Xi an 710032, China Department of Neurosurgery, Qingdao 401 Hospital of PLA, No 22 Minjiang Road, Qingdao 266071, China
    Brain Res Bull 99:84-94. 2013
    ..In conclusion, our study demonstrated that over-expression of Mash1 can improve GABAergic differentiation of BMSCs in vitro. ..
  49. ncbi request reprint [Changes and effects of group II metabotropic glutamate receptors in the cerebral cortex of rats after diffuse brain injuries coupled with hypopiesia secondary brain insults]
    Zhou Fei
    Department of Neurosurgery, Xijing Hospital, The Fourth Military Medical University, Xi an 710033, Shanxi, China
    Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 15:609-11. 2003
    ..To study the changes and effects of group II metabotropic glutamate receptors (mGluR) after diffuse brain injuries (DBI) coupled with hypopiesia secondary brain insults (SBI)...
  50. ncbi request reprint [Minimally invasive neurosurgery for removal of pituitary adenomas by neuroendoscope aided with sellar floor reconstruction]
    Xiang Zhang
    Neurosurgical Institute of Chinese PLA, Xijing Hospital, Fourth Military Medical University, Xi an 710032, China
    Zhonghua Yi Xue Za Zhi 90:2342-4. 2010
    ..To evaluate the effect of surgical technique and clinical curative effect for a unilateral endonasal-transsphenoidal approach in the removal of pituitary adenomas (PAs) by an endoscope-assisted technique with sellar floor reconstruction...
  51. doi request reprint The tropism of neurally differentiated bone marrow stromal cells towards C6 glioma
    Qianfa Long
    Xijing Institute of Clinical Neuroscience, Fourth Military Medical University, 17 Chang le West Road, Xi an 710032, China
    Neurosci Lett 504:135-40. 2011
    ..These results demonstrate that N-D-BMSCs as well as BMSCs have significant tropism towards C6 glioma...
  52. doi request reprint Genetically engineered bone marrow mesenchymal stem cells improve functional outcome in a rat model of epilepsy
    Qianfa Long
    Department of Neurosurgery, The Central Hospital of Xi an, Affiliated Hospital of Medical College of Xi an Jiao Tong University, No 185 Houzai Gate of North Street, Xi an 710003, China Xijing Institute of Clinical Neuroscience, Fourth Military Medical University, No 17 Chang le West Road, Xi an 710032, China
    Brain Res 1532:1-13. 2013
    ..Taken together, these data suggest that GE-BMSCs can improve the functional outcome in a rat model of epilepsy. ..
  53. ncbi request reprint Changes in metabotropic glutamate receptor 4 expression and the effects of L-2-amino-4-phosphonobutyrate in a rodent model of diffuse brain injury
    Hong Min Bai
    Department of Neurosurgery, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou 510010, China
    Chin J Traumatol 7:233-8. 2004
    ..To examine the changes in the expression of mGluR4 after diffuse brain injury (DBI) and to determine the role of its specific agonist L-2-amino-4-phosphonobutyrate (L-AP4) in vivo...
  54. ncbi request reprint The effect of cyclin D expression on cell proliferation in human gliomas
    Xiang Zhang
    Department of Neurosurgery, Xi Jing Hospital, The Fourth Military Medical University, Xi an, China
    J Clin Neurosci 12:166-8. 2005
    ..Cyclin D2 is weakly expressed and shows no marked relationship with any aspect of tumorigenesis. The exact contribution of cyclin D subtypes to cell cycle progression in neoplastic and reactive cells remains to be defined...
  55. pmc Up-regulated oncoprotein P28GANK correlates with proliferation and poor prognosis of human glioma
    Yang Yang
    Department of Neurosurgery, Xijing Hospital, The Fourth Military Medical University, 17 West Changle Road, Xi an 710032, China
    World J Surg Oncol 10:169. 2012
    ..The significance of p28GANK in gliomas remains unknown. This study aims to clarify the clinical significance of p28GANK in human gliomas...
  56. doi request reprint Effect of different mild hypoxia manipulations on kainic acid-induced seizures in the hippocampus of rats
    Yang Yang
    Department of Neurosurgery, Xijing Hospital, The Fourth Military Medical University, 17 West Changle Road, Xi an 710032, China
    Neurochem Res 38:123-32. 2013
    ..These findings might provide new ideas and methods for the clinical treatment of epilepsy...
  57. doi request reprint Acute neuroprotective effects of extremely low-frequency electromagnetic fields after traumatic brain injury in rats
    Yang Yang
    Department of Neurosurgery, Xijing Hospital, The Fourth Military Medical University, 17 West Changle Road, Xi an 710032, China
    Neurosci Lett 516:15-20. 2012
    ..These findings revealed that extremely low-frequency electromagnetic fields significantly prolong the window of opportunity for brain protection and enhance the intensity of neuroprotection after traumatic brain injury...
  58. doi request reprint Thioredoxin-1 attenuates post-ischemic neuronal apoptosis via reducing oxidative/nitrative stress
    Y H Ma
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, China
    Neurochem Int 60:475-83. 2012
    ..These results provide the information that thioredoxin is much more likely to succeed as a therapeutic approach to diminish oxidative/nitrative stress-induced neuronal apoptotic cell death in the ischemic brain...
  59. doi request reprint 14-3-3ζ positive expression is associated with a poor prognosis in patients with glioblastoma
    Xiaoliang Yang
    Institute of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xian, Shaanxi Province, People s Republic of China
    Neurosurgery 68:932-8; discussion 938. 2011
    ..When identifying clinical markers predicting clinical outcome, disease recurrence and resistance to therapies often determine the diagnosis and therapy of some cancer types...
  60. doi request reprint Salvianolic acid B attenuates brain damage and inflammation after traumatic brain injury in mice
    Tao Chen
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi Province 710032, People s Republic of China
    Brain Res Bull 84:163-8. 2011
    ..Thus SalB may have therapeutic potential for patients with TBI and perhaps other forms of acute brain injury...
  61. ncbi request reprint Neuritin expression and its relation with proliferation, apoptosis, and angiogenesis in human astrocytoma
    Lei Zhang
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 15 Changlexi Street, Xi an, Shaanxi Province, 710033, China
    Med Oncol 28:907-12. 2011
    ..In our study, we found neuritin is overexpressed in astrocytoma, which may be an important factor in tumorigenesis and progression of astrocytoma, and can be used as a target for biological therapy...
  62. doi request reprint The expression and significance of HIF-1alpha and GLUT-3 in glioma
    Yang Liu
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 17 Changle West Road, Xi an, 710032, China
    Brain Res 1304:149-54. 2009
    ..In conclusion, the expression of HIF-1alpha and GLUT-3 in glioma was correlated significantly with tumors' pathological grade, which can be taken as a pair of useful markers for predicting the biological behavior of glioma...
  63. pmc Spinal astrocytic activation contributes to mechanical allodynia in a rat chemotherapy-induced neuropathic pain model
    Xi tuan Ji
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, People s Republic of China
    PLoS ONE 8:e60733. 2013
    ..Thus, inhibiting spinal astrocytic activation may represent a novel therapeutic strategy for treating CNP...
  64. ncbi request reprint [Neuronavigator-guided microsurgery for resection of brain tumors]
    Xiang Zhang
    Department of Neurosurgery, Xijing Hospital, The Fourth Military Medical University, Xi an 710032, China
    Zhonghua Yi Xue Za Zhi 82:219-21. 2002
    ..To study locating accuracy for the brain tumors and their peri-structures by the neuronavigator and elucidate the microsurgical effects...
  65. ncbi request reprint [Differentiation of ectomesenchymal stem cells into dendritic cells in vitro induced by cytokines]
    Shi Jie Hu
    Department of Neurosurgery, Fourth Military Medical University, Xi an, China
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 28:1166-8. 2012
    ..To induce the differentiation of ectomesenchymal stem cells (EMSCs) into dentritic cells (DCs) in vitro...
  66. doi request reprint A randomized controlled study comparing omeprazole and cimetidine for the prophylaxis of stress-related upper gastrointestinal bleeding in patients with intracerebral hemorrhage
    Bo Lin Liu
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi Province, People s Republic of China
    J Neurosurg 118:115-20. 2013
    ..The aim of this study was to evaluate the effectiveness of omeprazole and cimetidine compared with a placebo in the prevention and management of stress-related UGI bleeding in patients with ICH...
  67. ncbi request reprint Expression of EphA2 in human astrocytic tumors: correlation with pathologic grade, proliferation and apoptosis
    Xia Li
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, China
    Tumour Biol 28:165-72. 2007
    ..Therefore, EphA2 may be a new biomarker for astrocytic tumors. It may also affect the proliferation and apoptosis of tumor cells and be an attractive therapy target for astrocytic tumors...
  68. doi request reprint The role of glutamate receptors in traumatic brain injury: implications for postsynaptic density in pathophysiology
    Peng Luo
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, 15 Changle xi Road, Xi an 710032, PR China
    Brain Res Bull 85:313-20. 2011
    ..The changes in the function and structure of these major PSD proteins are also induced by TBI, indicating that there is a more complicated mechanism associated with PSD proteins in the pathophysiological process of TBI...
  69. ncbi request reprint [Neuroendoscope-assisted endonasal-transsphenoidal surgery for pituitary neoplasms]
    Xiang Zhang
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, China
    Zhonghua Yi Xue Za Zhi 85:1535-7. 2005
    ..To evaluate the effect of curative effect of endonasal transsphenoidal approach for removal of pituitary neoplasms (PNs) assisted by neuroendoscopy...
  70. ncbi request reprint Traumatic injury induced homer-1a gene expression in cultured cortical neurons of rat
    Wei Dong Huang
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, Shannxi 710032, PR China
    Neurosci Lett 389:46-50. 2005
    ....
  71. doi request reprint Scaffold protein Homer 1: implications for neurological diseases
    Peng Luo
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, PR China
    Neurochem Int 61:731-8. 2012
    ....
  72. ncbi request reprint [Exogenous nitric oxide inhibits the proliferation of mouse neural progenitor cells]
    Xiang Zhang
    Institute of Neurosurgery of People s Liberation Army, Xijing Hospital, Fourth Military Medical University, Xi an 710032, China
    Zhonghua Yi Xue Za Zhi 83:1259-61. 2003
    ..To explore the inhibitive effect of exogenous nitric oxide (NO) on the proliferation of mouse neural progenitor cells (NPCs)...
  73. pmc Brain Tumor Stem-Like Cells Identified by Neural Stem Cell Marker CD15
    Xing gang Mao
    Department of Neurosurgery, Xijing Hospital, The Fourth Military Medical University, Xi an, Shaanxi Province, China
    Transl Oncol 2:247-57. 2009
    ..Therefore, CD15 can be used as a marker of stem-like cells derived from brain tumors that might contain CD133(-) BTSCs...
  74. doi request reprint Neuroprotective effect of osthole against acute ischemic stroke on middle cerebral ischemia occlusion in rats
    Xiaodong Chao
    Department of Neurosurgery, Xi Jing Institute of Clinical Neuroscience, Xi Jing Hospital, Fourth Military Medical University, Xi an, Shannxi 710032, China
    Brain Res 1363:206-11. 2010
    ..The study suggests the neuroprotective effect of osthole in the MCAO model of rats. The anti-oxidative action and anti-inflammatory property of osthole may contribute to a beneficial effect against stroke...
  75. doi request reprint Chordoid glioma: a case report and literature review
    Wei ping Liu
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xijing Hospital, Xi an, Shaanxi Province, People s Republic of China
    Neurologist 17:52-6. 2011
    ..It was first described by Brat in 1998. Because there is no detailed information available from the clinical perspective, we reviewed the literature...
  76. doi request reprint Vascular endothelial growth factor in cerebral ischemia
    Yihui Ma
    Institute of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, China
    J Neurosci Res 89:969-78. 2011
    ..In addition, recent studies indicate that VEGF enhances neurogenesis after ischemia. Therefore, further investigation is necessary to clarify the exact role of VEGF in neurogenesis...
  77. ncbi request reprint [Comparison of the intracranial pressure value in patients with hypertensive intracerebral hemorrhage treated with traditional craniotomy and puncture drainage]
    Shao Jun Song
    Institute of Neurosurgery of Chinese People s Liberation Army, Xijing Hospital, Fourth Military Medical University, Xi an 710033, Shanxi, China
    Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 15:532-4. 2003
    ..To compare the difference of intracranial pressure (ICP) in patients with hypertensive intracerebral hemorrhage (HICH) treated with two surgical procedures, traditional craniotomy and puncture drainage...
  78. ncbi request reprint Primary frontoparietal lobe convexity germinoma with dural invasion mimics meningioma
    Xituan Ji
    Department of Neurosurgery, Fourth Military Medical University, Xi an, P R China
    Neurosciences (Riyadh) 16:276-80. 2011
    ..Furthermore, we recommend that frozen biopsy sections should be taken routinely during surgery to aid in rapid diagnosis and effective therapy...
  79. ncbi request reprint Facial nerve function after excision of large acoustic neuromas via the suboccipital retrosigmoid approach
    Xiang Zhang
    Department of Neurosurgery, Xijing Hospital, The Fourth Military Medical University, Xi an, PR China
    J Clin Neurosci 12:405-8. 2005
    ..We recommend this approach for excision of large acoustic neuromas...
  80. ncbi request reprint Development of a rat C6 brain tumor model
    Xiang Zhang
    Neurosurgical Institute of PLA, Xijing Hospital, The Fourth Military Medical University, Xi an 710032, China
    Chin Med J (Engl) 115:455-7. 2002
    ..To establish rat C6 brain-tumor models and find a simple reliable index to judge tumor volume...
  81. ncbi request reprint One-stage apertura thoracis superior approach for four-vessel occlusion in rats
    Jian Liu
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an 710032, Shanxi Province, China
    Chin J Traumatol 15:13-6. 2012
    ....
  82. doi request reprint The role of excitatory amino acid transporters in cerebral ischemia
    Xiao dong Chao
    Department of Neurosurgery, Xi Jing Hospital, Fourth Military Medical University, Xi an, China
    Neurochem Res 35:1224-30. 2010
    ..Recent studies show that up-regulation of EAAT2 provides neuroprotection during ischemic insult. This review summarizes current knowledge regarding the role of EAATs in cerebral ischemia...
  83. ncbi request reprint Neuronal free Ca(2+)and BBB permeability and ultrastructure in head injury with secondary insult
    F Zhou
    Department of Neurosurgery, Xijing Hospital, Xian, P.R. China
    J Clin Neurosci 8:561-3. 2001
    ..05). CONCLUSION: In DAI alone and DAI with SBI, Ca(2+)overload and BBB permeability changes interact and both play important roles in the aggravation of brain damage...