Affiliation: Fourth Military Medical University
Zhong Y, Sun X, Zhang P, Qin X, Chen W, Guo Y, et al
. Identification and localization of xylose-binding proteins as potential biomarkers for liver fibrosis/cirrhosis. Mol Biosyst. 2016;12:598-605 pubmed publisher
Zhang Z, Jiang J, Wu X, Zhang M, Luo D, Zhang R, et al
. Chimeric antigen receptor T cell targeting EGFRvIII for metastatic lung cancer therapy. Front Med. 2019;13:57-68 pubmed publisher
..Therefore, CAR-T targeting EGFRvIII is a potential therapeutic strategy in preventing recurrence and metastasis of lung cancer after surgery. ..
Zhang R, Zhang Z, Liu Z, Wei D, Wu X, Bian H, et al
. Adoptive cell transfer therapy for hepatocellular carcinoma. Front Med. 2019;13:3-11 pubmed publisher
..In this review, we summarized the current application of ACT, the challenges encountered by CAR-T technology in HCC treatment, and some possible strategies for the future direction of immunotherapeutic research. ..
Shi W, Ju D, Li H, Yuan L, Cui J, Luo D, et al
. CD147 Promotes CXCL1 Expression and Modulates Liver Fibrogenesis. Int J Mol Sci. 2018;19: pubmed publisher
..Inhibition of CD147 attenuates CCl?-induced liver fibrosis and inflammation. Therefore, administration of targeting CD147 could be a promising therapeutic strategy in liver fibrosis. ..
Yang L, Jin L, Ke Y, Fan X, Zhang T, Zhang C, et al
. E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis. J Invest Dermatol. 2018;138:2568-2577 pubmed publisher
..Our study demonstrated that targeting K17 ubiquitination may be a potential therapeutic approach by attenuating STAT3 signaling in psoriasis. ..
Zhong Y, Zhang J, Yu H, Zhang J, Sun X, Chen W, et al
. Characterization and sub-cellular localization of GalNAc-binding proteins isolated from human hepatic stellate cells. Biochem Biophys Res Commun. 2015;468:906-12 pubmed publisher
Wei D, Li Q, Wang X, Wang Y, Xu J, Feng F, et al
. Oncolytic Newcastle disease virus expressing chimeric antibody enhanced anti-tumor efficacy in orthotopic hepatoma-bearing mice. J Exp Clin Cancer Res. 2015;34:153 pubmed publisher
..This study provides a new strategy of arming oncolytic NDV with therapeutic antibody to enhance anti-tumor efficacy of cancer therapy. ..
Li Q, Wei D, Feng F, Wang X, Li C, Chen Z, et al
. ?2,6-linked sialic acid serves as a high-affinity receptor for cancer oncolytic virotherapy with Newcastle disease virus. J Cancer Res Clin Oncol. 2017;143:2171-2181 pubmed publisher
..The study provides evidence of optimized therapeutic strategy in oncolytic virotherapy via partly defining ?2,6-sialylated receptor as a "cellular marker" for NDV. ..
Wei D, Xu J, Liu X, Chen Z, Bian H. Fighting Cancer with Viruses: Oncolytic Virus Therapy in China. Hum Gene Ther. 2017;: pubmed publisher
..Here, we focus on the studies that carried out in China to show the past, present, and future of oncolytic virotherapy in China. ..