Research Topics
| Yan Hua LuSummaryAffiliation: East China University of Science and Technology Country: China Publications
| Collaborators
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Detail Information
Publications
Tyrosinase inhibitory effect and inhibitory mechanism of tiliroside from raspberryYan Hua Lu
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, PR China
J Enzyme Inhib Med Chem 24:1154-60. 2009..5% inhibition of melanin production at the same concentration. These results suggested that tiliroside was a potent tyrosinase inhibitor and might be used as a skin-whitening agent and pigmentation medicine...
Citrus flavonoids in fruit and traditional Chinese medicinal food ingredients in ChinaYanhua Lu
State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Mailbox 311, Meilong Rd No 130, Shanghai 200237, China
Plant Foods Hum Nutr 61:57-65. 2006..74%) of hesperidin in the root of Liangmianzhen (Z. nitidum (Roxb.) DC), a relative of Sichuan pepper, which is a spice widely used in China...
Mechanism and inhibitory effect of galangin and its flavonoid mixture from Alpinia officinarum on mushroom tyrosinase and B16 murine melanoma cellsYan Hua Lu
State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, PR China
J Enzyme Inhib Med Chem 22:433-8. 2007..These observations suggest that galangin may be a whitening agent and a promising candidate for prevention of skin cancer. This is the first full scale report on the evaluation of the whitening effect of galangin...
Quality evaluation of Platycladus orientalis (L.) Franco through simultaneous determination of four bioactive flavonoids by high-performance liquid chromatographyYan Hua Lu
State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Box 311, 130 Meilong Road, Shanghai 200237, PR China
J Pharm Biomed Anal 41:1186-90. 2006..999. In addition, the contents of those four flavonoids in P. orientalis (L.) Franco growing in 12 different locations in China were compared to establish the effectiveness of the method...
Protective effects of the citrus flavanones to PC12 cells against cytotoxicity induced by hydrogen peroxideYan Hua Lu
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China
Neurosci Lett 484:6-11. 2010..All the above results suggest that these dietary antioxidants are potential candidates for use in the intervention for neurodegenerative diseases...
Phytochemical profiles of different mulberry (Morus sp.) species from ChinaWei Song
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China
J Agric Food Chem 57:9133-40. 2009..The high contents of functional compounds in mulberry juice, fruits, and leaves implied that they might be potential resources for the development of functional drinks and food...
Chemical fingerprint and quantitative analysis of Salvia plebeia R.Br. by high-performance liquid chromatographyXiao feng Jin
State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, PR China
J Pharm Biomed Anal 48:100-4. 2008..21-0.44 (caffeic acid), respectively. From the results obtained, the content of homoplantaginin was the highest. In addition, luteolin and luteolin-7-glucoside were isolated for the first time from S. plebeia...
Preparative isolation and purification of hydroxyanthraquinones from Rheum tanguticum Maxim. on normal phase silica gel: using a Flash Master Personal systemYong Zhi Zhang
State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai PR China
Prep Biochem Biotechnol 37:185-93. 2007..Their structures were ascertained by EI-MS, (1)H- and (13)C-NMR data, and by co-TLC and HPLC with the authentic samples available in our laboratory...
Multidrug resistance reversal effect of DMC derived from buds of Cleistocalyx operculatus in human hepatocellular tumor xenograft modelHai Ya Huang
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China
J Sci Food Agric 92:135-40. 2012..2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone (DMC) isolated from the buds of Cleistocalyx operculatus (Roxb.) Merr. et Perry (Myrtaceae), was investigated for its reversal effects on cancer cell MDR...
Protective effects of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone to PC12 cells against cytotoxicity induced by hydrogen peroxideMing Yuan Su
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, People s Republic of China
J Agric Food Chem 59:521-7. 2011....
Reversal effect of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone on multi-drug resistance in resistant human hepatocellular carcinoma cell line BEL-7402/5-FUHai Ya Huang
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China
Phytomedicine 18:1086-92. 2011..The mRNA expressions of MRP1 and GST-π and the protein expression of MRP1 were decreased by DMC. These data demonstrated that DMC could effectively reverse MDR in BEL-7402/5-FU cells...
In Vitro Investigation of 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone for Glycemic ControlYing Chun Hu
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, People s Republic of China
J Agric Food Chem 60:10683-8. 2012..Such effects highlight the therapeutic potential of DMC in the management of hyperglycemia...
Hepatoprotective effects of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone on CCl4-induced acute liver injury in miceWan Guo Yu
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China
J Agric Food Chem 59:12821-9. 2011....
In vitro anti-tumor activity of isorhamnetin isolated from Hippophae rhamnoides L. against BEL-7402 cellsBao-Song Teng
State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, PR China
Pharmacol Res 54:186-94. 2006..To our knowledge, this is the first report against human hepatocellular carcinoma cells (BEL-7402) of isorhamnetin...
Induction of apoptosis in K562 human leukemia cells by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalconeChun-Lin Ye
State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai 200237, PR China
Leuk Res 29:887-92. 2005..The resulting net effect could thus lead to a lower ratio of Bcl-2/Bax, which might be responsible for the DMC-induced apoptosis in K562 cells...
In vivo antitumor activity by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone in a solid human carcinoma xenograft modelChun-Lin Ye
State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai 200237, People's Republic of China
Cancer Chemother Pharmacol 56:70-4. 2005..60+/-0.80% of the total in mice injected with 150 mg/kg DMC). To our knowledge, this is the first time that chalcone compounds have been applied to a human tumor xenograft model...
Neuroprotective effects of Hypericum perforatum on trauma induced by hydrogen peroxide in PC12 cellsYan-Hua Lu
State Key Laboratory of Bioreactor Engineering, Institute of New World Biotechnology East China University of Science and Technology, Shanghai 200237, China
Am J Chin Med 32:397-405. 2004..This data suggests SEHP may be a candidate for application in neurodegenerative diseases such as Alzheimer's disease or Parkinson's disease...
In vitro anti-tumor activity of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone against six established human cancer cell linesChun-Lin Ye
State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai 200237, PR China
Pharmacol Res 50:505-10. 2004..To our knowledge, this is the first report on anti-tumor activity by DMC...
[Protective effects of Cleistocalyx operculatus on lipid peroxidation and trauma of neuronal cells]Yan-Hua Lu
State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai 200237, China
Zhongguo Zhong Yao Za Zhi 28:964-6. 2003..00 g x L(-1). CONCLUSION: Cleistocalyx operculatus may be used as antioxidant to prevent or delay the pathogenesis of neural cell diseases...
In vivo antitumor activity by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone in a solid human carcinoma xenograft modelChun-Lin Ye
State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai, 200237, China
Cancer Chemother Pharmacol 55:447-52. 2005..60+/-0.80% of the total in the 150-mg/kg DMC injection group). To our knowledge, this is the first time that chalcone compounds were applied to a human tumor xenograft model...
Flavonoids from Cleistocalyx operculatusChun-Lin Ye
State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai 200237, China
Phytochemistry 65:445-7. 2004..Their structures were determined on the basis of spectroscopic analyses (UV, IR, EIMS, (1)H, (13)C NMR and HMBC)...
[Study on HPLC fingerprint and quality control of Propolis]En-Yuan Zhu
Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
Zhongguo Zhong Yao Za Zhi 30:1423-5. 2005..RESULT: The chromatograms of Propolis from different producing areas were very similar. CONCLUSION: The quality of Propolis can be controlled by determination the HPLC fingerprint...
