Yan Hua Lu

Summary

Affiliation: East China University of Science and Technology
Country: China

Publications

  1. doi request reprint Tyrosinase inhibitory effect and inhibitory mechanism of tiliroside from raspberry
    Yan Hua Lu
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, PR China
    J Enzyme Inhib Med Chem 24:1154-60. 2009
  2. ncbi request reprint Black rice and anthocyanins induce inhibition of cholesterol absorption in vitro
    Shu Long Yao
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Box 283, 130 Meilong Road, Shanghai 200237, China
    Food Funct 4:1602-8. 2013
  3. ncbi request reprint Mechanism and inhibitory effect of galangin and its flavonoid mixture from Alpinia officinarum on mushroom tyrosinase and B16 murine melanoma cells
    Yan Hua Lu
    State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, PR China
    J Enzyme Inhib Med Chem 22:433-8. 2007
  4. doi request reprint Protective effects of the citrus flavanones to PC12 cells against cytotoxicity induced by hydrogen peroxide
    Yan Hua Lu
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China
    Neurosci Lett 484:6-11. 2010
  5. ncbi request reprint Citrus flavonoids in fruit and traditional Chinese medicinal food ingredients in China
    Yanhua Lu
    State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Mailbox 311, Meilong Rd No 130, Shanghai 200237, China
    Plant Foods Hum Nutr 61:57-65. 2006
  6. ncbi request reprint Quality evaluation of Platycladus orientalis (L.) Franco through simultaneous determination of four bioactive flavonoids by high-performance liquid chromatography
    Yan Hua Lu
    State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Box 311, 130 Meilong Road, Shanghai 200237, PR China
    J Pharm Biomed Anal 41:1186-90. 2006
  7. ncbi request reprint [Protective effects of Cleistocalyx operculatus on lipid peroxidation and trauma of neuronal cells]
    Yan Hua Lu
    State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai 200237, China
    Zhongguo Zhong Yao Za Zhi 28:964-6. 2003
  8. ncbi request reprint Induction of apoptosis in K562 human leukemia cells by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone
    Chun Lin Ye
    State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai 200237, PR China
    Leuk Res 29:887-92. 2005
  9. ncbi request reprint In vivo antitumor activity by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone in a solid human carcinoma xenograft model
    Chun Lin Ye
    State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai, 200237, China
    Cancer Chemother Pharmacol 55:447-52. 2005
  10. doi request reprint Phytochemical profiles of different mulberry (Morus sp.) species from China
    Wei Song
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China
    J Agric Food Chem 57:9133-40. 2009

Collaborators

Detail Information

Publications27

  1. doi request reprint Tyrosinase inhibitory effect and inhibitory mechanism of tiliroside from raspberry
    Yan Hua Lu
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, PR China
    J Enzyme Inhib Med Chem 24:1154-60. 2009
    ..5% inhibition of melanin production at the same concentration. These results suggested that tiliroside was a potent tyrosinase inhibitor and might be used as a skin-whitening agent and pigmentation medicine...
  2. ncbi request reprint Black rice and anthocyanins induce inhibition of cholesterol absorption in vitro
    Shu Long Yao
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Box 283, 130 Meilong Road, Shanghai 200237, China
    Food Funct 4:1602-8. 2013
    ..These findings provide important evidence that anthocyanins may partly contribute to the inhibitory effects of black rice on cholesterol absorption, and thus may be applied for the prevention and treatment of hypercholesterolaemia. ..
  3. ncbi request reprint Mechanism and inhibitory effect of galangin and its flavonoid mixture from Alpinia officinarum on mushroom tyrosinase and B16 murine melanoma cells
    Yan Hua Lu
    State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, PR China
    J Enzyme Inhib Med Chem 22:433-8. 2007
    ..These observations suggest that galangin may be a whitening agent and a promising candidate for prevention of skin cancer. This is the first full scale report on the evaluation of the whitening effect of galangin...
  4. doi request reprint Protective effects of the citrus flavanones to PC12 cells against cytotoxicity induced by hydrogen peroxide
    Yan Hua Lu
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China
    Neurosci Lett 484:6-11. 2010
    ..All the above results suggest that these dietary antioxidants are potential candidates for use in the intervention for neurodegenerative diseases...
  5. ncbi request reprint Citrus flavonoids in fruit and traditional Chinese medicinal food ingredients in China
    Yanhua Lu
    State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Mailbox 311, Meilong Rd No 130, Shanghai 200237, China
    Plant Foods Hum Nutr 61:57-65. 2006
    ..74%) of hesperidin in the root of Liangmianzhen (Z. nitidum (Roxb.) DC), a relative of Sichuan pepper, which is a spice widely used in China...
  6. ncbi request reprint Quality evaluation of Platycladus orientalis (L.) Franco through simultaneous determination of four bioactive flavonoids by high-performance liquid chromatography
    Yan Hua Lu
    State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Box 311, 130 Meilong Road, Shanghai 200237, PR China
    J Pharm Biomed Anal 41:1186-90. 2006
    ..999. In addition, the contents of those four flavonoids in P. orientalis (L.) Franco growing in 12 different locations in China were compared to establish the effectiveness of the method...
  7. ncbi request reprint [Protective effects of Cleistocalyx operculatus on lipid peroxidation and trauma of neuronal cells]
    Yan Hua Lu
    State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai 200237, China
    Zhongguo Zhong Yao Za Zhi 28:964-6. 2003
    ..To observe the protective effects of Cleistocalyx operculatus on lipid peroxidation in rat liver microsomes and on the trauma of PC12 cells induced by H2O2...
  8. ncbi request reprint Induction of apoptosis in K562 human leukemia cells by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone
    Chun Lin Ye
    State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai 200237, PR China
    Leuk Res 29:887-92. 2005
    ..The resulting net effect could thus lead to a lower ratio of Bcl-2/Bax, which might be responsible for the DMC-induced apoptosis in K562 cells...
  9. ncbi request reprint In vivo antitumor activity by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone in a solid human carcinoma xenograft model
    Chun Lin Ye
    State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai, 200237, China
    Cancer Chemother Pharmacol 55:447-52. 2005
    ..60+/-0.80% of the total in the 150-mg/kg DMC injection group). To our knowledge, this is the first time that chalcone compounds were applied to a human tumor xenograft model...
  10. doi request reprint Phytochemical profiles of different mulberry (Morus sp.) species from China
    Wei Song
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China
    J Agric Food Chem 57:9133-40. 2009
    ..The high contents of functional compounds in mulberry juice, fruits, and leaves implied that they might be potential resources for the development of functional drinks and food...
  11. ncbi request reprint In vitro anti-tumor activity of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone against six established human cancer cell lines
    Chun Lin Ye
    State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai 200237, PR China
    Pharmacol Res 50:505-10. 2004
    ..To our knowledge, this is the first report on anti-tumor activity by DMC...
  12. ncbi request reprint In vivo antitumor activity by 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone in a solid human carcinoma xenograft model
    Chun Lin Ye
    State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai 200237, People s Republic of China
    Cancer Chemother Pharmacol 56:70-4. 2005
    ..60+/-0.80% of the total in mice injected with 150 mg/kg DMC). To our knowledge, this is the first time that chalcone compounds have been applied to a human tumor xenograft model...
  13. doi request reprint Chemical fingerprint and quantitative analysis of Salvia plebeia R.Br. by high-performance liquid chromatography
    Xiao feng Jin
    State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, PR China
    J Pharm Biomed Anal 48:100-4. 2008
    ..21-0.44 (caffeic acid), respectively. From the results obtained, the content of homoplantaginin was the highest. In addition, luteolin and luteolin-7-glucoside were isolated for the first time from S. plebeia...
  14. ncbi request reprint In vitro anti-tumor activity of isorhamnetin isolated from Hippophae rhamnoides L. against BEL-7402 cells
    Bao Song Teng
    State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, PR China
    Pharmacol Res 54:186-94. 2006
    ..To our knowledge, this is the first report against human hepatocellular carcinoma cells (BEL-7402) of isorhamnetin...
  15. ncbi request reprint Neuroprotective effects of Hypericum perforatum on trauma induced by hydrogen peroxide in PC12 cells
    Yan Hua Lu
    State Key Laboratory of Bioreactor Engineering, Institute of New World Biotechnology East China University of Science and Technology, Shanghai 200237, China
    Am J Chin Med 32:397-405. 2004
    ..This data suggests SEHP may be a candidate for application in neurodegenerative diseases such as Alzheimer's disease or Parkinson's disease...
  16. doi request reprint Multidrug resistance reversal effect of DMC derived from buds of Cleistocalyx operculatus in human hepatocellular tumor xenograft model
    Hai Ya Huang
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China
    J Sci Food Agric 92:135-40. 2012
    ..2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone (DMC) isolated from the buds of Cleistocalyx operculatus (Roxb.) Merr. et Perry (Myrtaceae), was investigated for its reversal effects on cancer cell MDR...
  17. ncbi request reprint Inhibitory effects of Citrus flavonoids on starch digestion and antihyperglycemic effects in HepG2 cells
    Wei Shen
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, People s Republic of China
    J Agric Food Chem 60:9609-19. 2012
    ..This work suggests that Citrus flavonoids might be potentially used for the prevention of postprandial hyperglycemia...
  18. ncbi request reprint Preparative isolation and purification of hydroxyanthraquinones from Rheum tanguticum Maxim. on normal phase silica gel: using a Flash Master Personal system
    Yong Zhi Zhang
    State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai PR China
    Prep Biochem Biotechnol 37:185-93. 2007
    ..Their structures were ascertained by EI-MS, (1)H- and (13)C-NMR data, and by co-TLC and HPLC with the authentic samples available in our laboratory...
  19. doi request reprint Protective effects of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone to PC12 cells against cytotoxicity induced by hydrogen peroxide
    Ming Yuan Su
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, People s Republic of China
    J Agric Food Chem 59:521-7. 2011
    ....
  20. doi request reprint 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone promoted glucose uptake and imposed a paradoxical effect on adipocyte differentiation in 3T3-L1 cells
    Ying Chun Hu
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, People s Republic of China
    J Agric Food Chem 62:1898-904. 2014
    ..01 vs differentiation control group), and 5 μM DMC did not impose a significant effect. It was demonstrated that the effect of DMC in lipid accumulation was controlled by the expression of PPAR-γ. ..
  21. ncbi request reprint Flavonoids from Cleistocalyx operculatus
    Chun Lin Ye
    State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai 200237, China
    Phytochemistry 65:445-7. 2004
    ..Their structures were determined on the basis of spectroscopic analyses (UV, IR, EIMS, (1)H, (13)C NMR and HMBC)...
  22. doi request reprint Comparison of inhibitory activities and mechanisms of five mulberry plant bioactive components against α-glucosidase
    Hao He
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China
    J Agric Food Chem 61:8110-9. 2013
    ..This work provides useful information for the understanding of the ligands-α-glucosidase interactions and identifies oxyresveratrol as a potent α-glucosidase inhibitor. ..
  23. doi request reprint In vitro investigation of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone for glycemic control
    Ying Chun Hu
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, People s Republic of China
    J Agric Food Chem 60:10683-8. 2012
    ..Such effects highlight the therapeutic potential of DMC in the management of hyperglycemia...
  24. doi request reprint Reversal effect of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone on multi-drug resistance in resistant human hepatocellular carcinoma cell line BEL-7402/5-FU
    Hai Ya Huang
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China
    Phytomedicine 18:1086-92. 2011
    ..The mRNA expressions of MRP1 and GST-π and the protein expression of MRP1 were decreased by DMC. These data demonstrated that DMC could effectively reverse MDR in BEL-7402/5-FU cells...
  25. doi request reprint 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone protects the impaired insulin secretion induced by glucotoxicity in pancreatic β-cells
    Ying Chun Hu
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P R China
    J Agric Food Chem 62:1602-8. 2014
    ..The results indicated the potential application of DMC in the intervention against glucotoxicity-induced hyperglycemia. ..
  26. doi request reprint Hepatoprotective effects of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone on CCl4-induced acute liver injury in mice
    Wan Guo Yu
    State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China
    J Agric Food Chem 59:12821-9. 2011
    ....
  27. ncbi request reprint [Study on HPLC fingerprint and quality control of Propolis]
    En Yuan Zhu
    Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    Zhongguo Zhong Yao Za Zhi 30:1423-5. 2005
    ..To study on HPLC fingerprint of Propolis and to control it's quality...