Li Lin Du

Summary

Country: China

Publications

  1. pmc A piggyBac transposon-based mutagenesis system for the fission yeast Schizosaccharomyces pombe
    Jun Li
    National Institute of Biological Sciences, Beijing 102206, China
    Nucleic Acids Res 39:e40. 2011
  2. pmc Global analysis of fission yeast mating genes reveals new autophagy factors
    Ling Ling Sun
    National Institute of Biological Sciences, Beijing, China
    PLoS Genet 9:e1003715. 2013
  3. doi request reprint Phosphorylation-dependent assembly and coordination of the DNA damage checkpoint apparatus by Rad4(TopBP¹)
    Meng Qu
    National Institute of Biological Sciences, 7 Science Park Road, ZGC Life Science Park, Beijing 102206, China
    Mol Cell 51:723-36. 2013
  4. doi request reprint Multiple end joining mechanisms repair a chromosomal DNA break in fission yeast
    Peng Li
    National Institute of Biological Sciences, 7 Science Park Road, Zhongguancun Life Science Park, Beijing, China
    DNA Repair (Amst) 11:120-30. 2012
  5. pmc Phosphorylation-dependent interactions between Crb2 and Chk1 are essential for DNA damage checkpoint
    Meng Qu
    College of Biological Sciences, China Agricultural University, Beijing, China
    PLoS Genet 8:e1002817. 2012
  6. pmc Global fitness profiling of fission yeast deletion strains by barcode sequencing
    Tian Xu Han
    National Institute of Biological Sciences, 7 Science Park Road, Zhongguancun Life Science Park, Beijing, 102206, PR China
    Genome Biol 11:R60. 2010
  7. pmc Mdb1, a fission yeast homolog of human MDC1, modulates DNA damage response and mitotic spindle function
    Yi Wei
    College of Life Sciences, Beijing Normal University, Beijing, China National Institute of Biological Sciences, Beijing, China
    PLoS ONE 9:e97028. 2014
  8. ncbi request reprint piggyBac transposon-based insertional mutagenesis for the fission yeast Schizosaccharomyces pombe
    Jun Li
    National Institute of Biological Sciences, 7 Science Park Road, Zhongguancun Life Science Park, Beijing, 102206, People s Republic of China
    Methods Mol Biol 1163:213-22. 2014

Collaborators

Detail Information

Publications8

  1. pmc A piggyBac transposon-based mutagenesis system for the fission yeast Schizosaccharomyces pombe
    Jun Li
    National Institute of Biological Sciences, Beijing 102206, China
    Nucleic Acids Res 39:e40. 2011
    ..From another screen for cdc25-22 suppressors, we obtained multiple alleles of wee1 as expected. The success of these two screens demonstrated the usefulness of this PB-mediated mutagenesis tool for fission yeast...
  2. pmc Global analysis of fission yeast mating genes reveals new autophagy factors
    Ling Ling Sun
    National Institute of Biological Sciences, Beijing, China
    PLoS Genet 9:e1003715. 2013
    ..Our study sheds new light on the evolutionary diversity of the autophagy machinery and establishes the fission yeast as a useful model for dissecting the mechanisms of autophagy...
  3. doi request reprint Phosphorylation-dependent assembly and coordination of the DNA damage checkpoint apparatus by Rad4(TopBP¹)
    Meng Qu
    National Institute of Biological Sciences, 7 Science Park Road, ZGC Life Science Park, Beijing 102206, China
    Mol Cell 51:723-36. 2013
    ..Finally, we show that the simultaneous interaction of a single Rad4(TopBP1) molecule with both Thr187 phosphorylation sites in a Crb2(53BP1) dimer is essential for establishing the DNA damage checkpoint. ..
  4. doi request reprint Multiple end joining mechanisms repair a chromosomal DNA break in fission yeast
    Peng Li
    National Institute of Biological Sciences, 7 Science Park Road, Zhongguancun Life Science Park, Beijing, China
    DNA Repair (Amst) 11:120-30. 2012
    ..The chromosomal repair assay we describe here should provide a useful tool for further exploration of the end joining repair mechanisms in fission yeast...
  5. pmc Phosphorylation-dependent interactions between Crb2 and Chk1 are essential for DNA damage checkpoint
    Meng Qu
    College of Biological Sciences, China Agricultural University, Beijing, China
    PLoS Genet 8:e1002817. 2012
    ..These results suggest that the main role of Crb2 and 9-1-1 in DNA damage checkpoint signaling is recruiting Chk1 to sites of DNA lesions...
  6. pmc Global fitness profiling of fission yeast deletion strains by barcode sequencing
    Tian Xu Han
    National Institute of Biological Sciences, 7 Science Park Road, Zhongguancun Life Science Park, Beijing, 102206, PR China
    Genome Biol 11:R60. 2010
    ..Here we use deep sequencing to accurately characterize the barcode sequences in the deletion library, thus enabling the quantitative measurement of the fitness of fission yeast deletion strains by barcode sequencing...
  7. pmc Mdb1, a fission yeast homolog of human MDC1, modulates DNA damage response and mitotic spindle function
    Yi Wei
    College of Life Sciences, Beijing Normal University, Beijing, China National Institute of Biological Sciences, Beijing, China
    PLoS ONE 9:e97028. 2014
    ..Loss of Mdb1 or mutating its phospho-binding residues makes cells more resistant to the microtubule depolymerizing drug thiabendazole. We propose that Mdb1 performs dual roles in DDR and mitotic spindle regulation. ..
  8. ncbi request reprint piggyBac transposon-based insertional mutagenesis for the fission yeast Schizosaccharomyces pombe
    Jun Li
    National Institute of Biological Sciences, 7 Science Park Road, Zhongguancun Life Science Park, Beijing, 102206, People s Republic of China
    Methods Mol Biol 1163:213-22. 2014
    ....