Zhi jun Dai

Summary

Country: China

Publications

  1. ncbi request reprint [HER-2 expression in local advanced breast cancer and the efficacy of neoadjuvant chemotherapy regimens]
    Zhi jun Dai
    Department of Oncology, Second Hospital of Xi an Jiaotong University, Xi an 710004, China
    Nan Fang Yi Ke Da Xue Xue Bao 27:1397-9. 2007
  2. pmc Anti-angiogenic effect of the total flavonoids in Scutellaria barbata D. Don
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital of Xi an Jiaotong University, Xi an 710004, China
    BMC Complement Altern Med 13:150. 2013
  3. pmc Targeted inhibition of mammalian target of rapamycin (mTOR) enhances radiosensitivity in pancreatic carcinoma cells
    Zhi jun Dai
    Department of Oncology, Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an, People s Republic of China
    Drug Des Devel Ther 7:149-59. 2013
  4. pmc Antiproliferative and apoptotic effects of β-elemene on human hepatoma HepG2 cells
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital of Xi an Jiaotong University, Xi an 710004, China
    Cancer Cell Int 13:27. 2013
  5. ncbi request reprint Protective effects of Scutellaria barbata against rat liver tumorigenesis
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital of Xi an Jiaotong University, Xi an, China
    Asian Pac J Cancer Prev 14:261-5. 2013
  6. pmc Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in Vitro and in Vivo
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an, 710004, China
    Cancer Cell Int 12:53. 2012
  7. ncbi request reprint Sonodynamic therapy (SDT): a novel treatment of cancer based on sonosensitizer liposome as a new drug carrier
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an 710004, China
    Med Hypotheses 80:300-2. 2013
  8. pmc Antitumor effects of rapamycin in pancreatic cancer cells by inducing apoptosis and autophagy
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an 710004, China
    Int J Mol Sci 14:273-85. 2012
  9. doi request reprint Total flavonoids of Scutellaria barbata inhibit invasion of hepatocarcinoma via MMP/TIMP in vitro
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an 710004, China
    Molecules 18:934-50. 2013
  10. pmc Up-regulation of hypoxia inducible factor-1α by cobalt chloride correlates with proliferation and apoptosis in PC-2 cells
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an, China
    J Exp Clin Cancer Res 31:28. 2012

Collaborators

Detail Information

Publications41

  1. ncbi request reprint [HER-2 expression in local advanced breast cancer and the efficacy of neoadjuvant chemotherapy regimens]
    Zhi jun Dai
    Department of Oncology, Second Hospital of Xi an Jiaotong University, Xi an 710004, China
    Nan Fang Yi Ke Da Xue Xue Bao 27:1397-9. 2007
    ..To investigate the relationship between HER-2 expression and the efficacy of neoadjuvant chemotherapy in local advanced breast cancer...
  2. pmc Anti-angiogenic effect of the total flavonoids in Scutellaria barbata D. Don
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital of Xi an Jiaotong University, Xi an 710004, China
    BMC Complement Altern Med 13:150. 2013
    ..However, the antitumor molecular mechanism of S. barbata was still unclear. This study aimed to investigate the inhibitory effects of the total flavones in S. barbata (TF-SB) on angiogenesis...
  3. pmc Targeted inhibition of mammalian target of rapamycin (mTOR) enhances radiosensitivity in pancreatic carcinoma cells
    Zhi jun Dai
    Department of Oncology, Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an, People s Republic of China
    Drug Des Devel Ther 7:149-59. 2013
    ..The results demonstrated that RPM effectively enhanced the radiosensitivity of pancreatic carcinoma cells...
  4. pmc Antiproliferative and apoptotic effects of β-elemene on human hepatoma HepG2 cells
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital of Xi an Jiaotong University, Xi an 710004, China
    Cancer Cell Int 13:27. 2013
    ..In this study, the antitumor effect of β-elemene on a human hepatoma cell line, HepG2, and the mechanism involved have been investigated...
  5. ncbi request reprint Protective effects of Scutellaria barbata against rat liver tumorigenesis
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital of Xi an Jiaotong University, Xi an, China
    Asian Pac J Cancer Prev 14:261-5. 2013
    ..05). Content of MDA determined in liver was significantly decreased, and level of SOD elevated by CE-SB. CE-SB can inhibit experimental liver tumorigenesis and relieve hepatic injury in rats...
  6. pmc Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in Vitro and in Vivo
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an, 710004, China
    Cancer Cell Int 12:53. 2012
    ..abstract:..
  7. ncbi request reprint Sonodynamic therapy (SDT): a novel treatment of cancer based on sonosensitizer liposome as a new drug carrier
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an 710004, China
    Med Hypotheses 80:300-2. 2013
    ..SDT with low-intensity ultrasound combined with a sonosensitizer may be a promising approach to cancer therapy...
  8. pmc Antitumor effects of rapamycin in pancreatic cancer cells by inducing apoptosis and autophagy
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an 710004, China
    Int J Mol Sci 14:273-85. 2012
    ..The results demonstrated that Rapa could effectively inhibit proliferation and induce apoptosis and autophagy in PC-2 cells...
  9. doi request reprint Total flavonoids of Scutellaria barbata inhibit invasion of hepatocarcinoma via MMP/TIMP in vitro
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an 710004, China
    Molecules 18:934-50. 2013
    ..The present study indicates that TF-SB could reduce the metastatic capability of MHCC97H cell, probably through decrease of the MMP expression, and simultaneous increase of the TIMP expression...
  10. pmc Up-regulation of hypoxia inducible factor-1α by cobalt chloride correlates with proliferation and apoptosis in PC-2 cells
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an, China
    J Exp Clin Cancer Res 31:28. 2012
    ..This study investigated the variation of hypoxia-inducible factor-1α(HIF-1α) expression and the apoptosis effect of hypoxia stimulated by cobalt chloride (CoCl(2)) in pancreatic cancer PC-2 cells...
  11. doi request reprint In vitro and in vivo antitumor activity of Scutellaria barbate extract on murine liver cancer
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an 710004, China
    Molecules 16:4389-400. 2011
    ..Furthermore, CE-SB could improve immune function of H22 tumor bearing mice. Together these results indicate that CE-SB has antitumor activity and seems to be safe and effective for the use of anti-tumor therapy...
  12. ncbi request reprint [Antitumor and immune-modulating effects of Scutellaria barbata extract in mice bearing hepatocarcinoma H22 cells-derived tumor]
    Zhi jun Dai
    Department of Oncology, Second Hospital of Xi an Jiaotong University, Xi an 710004, China
    Nan Fang Yi Ke Da Xue Xue Bao 28:1835-7. 2008
    ..To investigate the effects of Scutellaria barbata extract (ESB) in suppressing tumor growth and modulating the immune functions in mice bearing tumors derived from hepatocarcinoma H22 cells...
  13. ncbi request reprint [Inhibitory effects of Scutellaria barbate extracts on diethylnitrosamine-induced hepatocarcinoma in rats]
    Zhi jun Dai
    Department of Oncology, Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an 710004, China
    Zhong Yao Cai 32:568-71. 2009
    ..To investigate the inhibitory effects of Scutellaria barbate extracts on diethylnitrosamine-induced hepatocarcinoma in rats...
  14. doi request reprint Matrine induces apoptosis in gastric carcinoma cells via alteration of Fas/FasL and activation of caspase-3
    Zhi jun Dai
    Department of Oncology, Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xiwu Road 157, Xi an 710004, Shaanxi Province, PR China
    J Ethnopharmacol 123:91-6. 2009
    ..In this study, the mechanism of matrine inducing the apoptosis of gastric carcinoma cells was investigated...
  15. pmc Scutellaria barbate extract induces apoptosis of hepatoma H22 cells via the mitochondrial pathway involving caspase-3
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an 710004, Shaanxi Province, China
    World J Gastroenterol 14:7321-8. 2008
    ..To study the growth inhibitory and apoptotic effects of Scutellaria barbata D.Don (S. barbata) and to determine the underlying mechanism of its antitumor activity in mouse liver cancer cell line H22...
  16. ncbi request reprint [Effects of Scutellaria Barbata drug-containing serum on apoptosis and mitochondrial transmembrane potential of hepatoma H22 cells]
    Zhi jun Dai
    Department of Oncology, the Second Affiliated Hospital of Medical College, Xi an Jiaotong University, Xi an, Shaanxi Province 710004, China
    Zhong Xi Yi Jie He Xue Bao 6:821-6. 2008
    ..To investigate the effects of serum containing Scutellaria Barbata extract (ESB) on apoptosis rate and mitochondrial transmembrane potential (MTP) of liver cancer cell line H22 from mice in vitro...
  17. ncbi request reprint [Anti-proliferative and apoptosis-inducing activity of Scutellaria barbate containing serum on mouse's hepatoma H22 cells]
    Zhi jun Dai
    Department of Oncology, Second Hospital of Xi an Jiaotong University, Xi an 710004, China
    Zhong Yao Cai 31:550-3. 2008
    ..To investigate the effects of Scutellaria barbate extract (ESB) on suppressing proliferation and inducing apoptosis of mouse hepatoma H22 cells...
  18. ncbi request reprint [Apoptotic mechanism of gastric carcinoma cells induced by matrine injection]
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital, Xi an Jiaotong University Medical College, Xi an 710004, China
    Zhonghua Wei Chang Wai Ke Za Zhi 11:261-5. 2008
    ..To investigate the mechanism of gastric carcinoma cells apoptosis induced by matrine injection in vitro...
  19. doi request reprint [Scutellaria barbata extract enhances efficacy and reduces toxicity of chemotherapy in hepatoma H22-bearing mice]
    Zhi jun Dai
    Department of Oncology, Second Hospital, School of Medicine, Xi an Jiaotong University, Xi an, Shannxi Province 710004, China
    Zhong Xi Yi Jie He Xue Bao 6:720-4. 2008
    ..To study the assistant effect of Scutellaria barbata extract (ESB) in 5-fluorouracil (5-FU) chemotherapy...
  20. ncbi request reprint [Effect of matrine injections on invasion and metastasis of gastric carcinoma SGC-7901 cells in vitro]
    Zhi jun Dai
    Department of Oncology, The Second Hospital of Xi an Jiaotong University, Xi an 710004, China
    Zhong Yao Cai 30:815-9. 2007
    ..To investigate the effect of matrine injections on invasion and metastasis of gastric carcinoma SGC-7901 cells in vitro...
  21. ncbi request reprint Induction of apoptosis by total flavonoids from Scutellaria barbata D. Don in human hepatocarcinoma MHCC97-H cells via the mitochondrial pathway
    Jie Gao
    Department of Oncology, The Second Affiliated Hospital of Xi an Jiaotong University, Xi an, 710004, China
    Tumour Biol 35:2549-59. 2014
    ..These results suggest that TF-SB induces apoptosis in MHCC97-H cells through the mitochondrial pathway. ..
  22. ncbi request reprint [Chemopreventive effect of tamoxifen combined with celecoxib on DMBA-induced breast cancer in rats]
    Hua feng Kang
    Department of Oncologic Surgery, The Second Affiliated Hospital, School of Medcine, Xioan Jiaotong University, Xioan, Shaanxi, 710004, P R China
    Ai Zheng 25:1346-50. 2006
    ..This study was to evaluate the chemopreventive effect of tamoxifen combined with celecoxib, a COX-2 selective inhibitor, on 7,12-dimethylbenz anthracene (DMBA)-induced breast cancer in rats...
  23. pmc The effect of RHIZOMA COPTIDIS and COPTIS CHINENSIS aqueous extract on radiation-induced skin injury in a rat model
    Xi jing Wang
    Department of Oncology, The Second Affiliated Hospital of Xi an Jiaotong University, Xi an, 710004, China
    BMC Complement Altern Med 13:105. 2013
    ..But, the protective mechanism of RHIZOMA COPTIDIS and COPTIS CHINENSIS in radiation-induced skin injury remains unclear...
  24. ncbi request reprint Down-regulation of survivin expression by small interfering RNA induces pancreatic cancer cell apoptosis and enhances its radiosensitivity
    Hai Tao Guan
    Department of Oncosurgery, the Second Affiliated Hospital of Xi an Jiaotong University Medical College, 157 West 5th Road, Xi an 710004, Shaanxi Province, China
    World J Gastroenterol 12:2901-7. 2006
    ..To investigate the inhibitory effect of small interfering RNA (siRNA) on the expression of survivin in pancreatic cancer cell line PC-2 and the role of siRNA in inducing PC-2 cell apoptosis and enhancing its radiosensitivity...
  25. ncbi request reprint Chrysanthemum indicum ethanolic extract inhibits invasion of hepatocellular carcinoma via regulation of MMP/TIMP balance as therapeutic target
    Zhi Dong Wang
    Department of Surgery, The Second Affiliated Hospital, School of Medicine, Xi an Jiaotong University, Shaanxi Province, PR China
    Oncol Rep 23:413-21. 2010
    ..It is suggested that Chrysanthemum indicum is a potential novel therapeutic medicinal plant for treatment of HCC or cancer invasion and metastasis...
  26. pmc Saikosaponin-d increases the radiosensitivity of smmc-7721 hepatocellular carcinoma cells by adjusting the g0/g1 and g2/m checkpoints of the cell cycle
    Bao Feng Wang
    Department of Oncology, Second Affiliated Hospital of Medical School, Xi an Jiaotong University, Xi an 710004, P, R, China
    BMC Complement Altern Med 13:263. 2013
    ..To investigate the radiosensitizing effect of SSd and its possible mechanism, we combined SSd with radiation therapy to treat SMMC-7721 hepatocellular carcinoma cells under oxia and hypoxia...
  27. ncbi request reprint Effects of interleukin-10 polymorphisms (rs1800896, rs1800871, and rs1800872) on breast cancer risk: evidence from an updated meta-analysis
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital of Xi an Jiaotong University, Xi an, China
    Genet Test Mol Biomarkers 18:439-45. 2014
    ..The associations between Interleukin-10 (IL-10) polymorphisms and breast cancer (BC) risk are inconsistent. This study was aimed to evaluate the relationship between IL-10 polymorphisms (rs1800896, rs1800871, and rs1800872) and BC risk...
  28. ncbi request reprint Esophageal cancer with esophageal duplication cyst
    Zhi jun Dai
    Department of Oncology, The Second Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an, China
    Ann Thorac Surg 96:e15-6. 2013
    ..The postoperative pathology report confirmed the diagnosis of esophageal squamous cancer (ulcer type) and esophageal duplication cyst with calcification. ..
  29. ncbi request reprint [Chemopreventive effect of celecoxib against DMBA-induced breast cancer and its mechanism]
    Hua feng Kang
    Department of Oncological Surgery, Second Affiliated Hospital, School of Medicine, Xi an Jiaotong University, Xi an 710004, China
    Nan Fang Yi Ke Da Xue Xue Bao 26:1599-602. 2006
    ..To evaluate the chemopreventive effect of celecoxib, a specific cyclooxegenease-2 (COX-2) inhibitor, on chemically induced breast cancer of rats and its effect on COX-2 expression...
  30. pmc RUNX3 gene promoter demethylation by 5-Aza-CdR induces apoptosis in breast cancer MCF-7 cell line
    Hua feng Kang
    Department of Oncology, The Second Affiliated Hospital of Xi an Jiaotong University, Xi an, People s Republic of China
    Onco Targets Ther 6:411-7. 2013
    ....
  31. ncbi request reprint [Role of vascular endothelial growth factor in rats with severe acute pancreatitis]
    Shun Le Li
    Department of General Surgery, Xi an Jiaotong University College of Medicine, Xi an 710004, China
    Nan Fang Yi Ke Da Xue Xue Bao 31:187-9. 2011
    ..To investigate the role of vascular endothelial growth factor (VEGF) in the pathogenesis of severe acute pancreatitis (SAP) in rats...
  32. ncbi request reprint Polymerase synthesis and potential interference of a small-interfering RNA targeting hPim-2
    Shu Qun Zhang
    Second Hospital of Xi an Jiaotong University, Xi an 710004, Shaanxi Province, China
    World J Gastroenterol 10:2657-60. 2004
    ..To synthesize three small-interference RNAs (siRNAs) by T7 RNA polymerase-catalyzed reaction, and to investigate their efficacy on modulating the expression of serine/threonine kinase Pim-2 in human colon cancer cell line...
  33. ncbi request reprint [Expression of survivin in different stages of carcinogenesis and progression of breast cancer]
    Shu Qun Zhang
    Department of Oncology, The Second Hospital, Xi an Jiaotong University, PR China
    Ai Zheng 23:697-700. 2004
    ....
  34. ncbi request reprint Inhibiting gastric cancer-associated angiogenesis by CIAPIN1 siRNA
    Kun Yan
    Department of General Surgery, Second Affiliated Hospital, Xi an Jiaotong University, Xi an, China
    Cancer Biol Ther 8:1058-63. 2009
    ..Our findings support that selective inhibition of CIAPIN1 alone plays an instrumental role on gastric cancer associated angiogenesis...
  35. ncbi request reprint [Effects of hypertonic saline on erythrocyte adherence function and bacterial infection of hemorrhagic shock rabbits]
    Han chen Li
    Department of General Surgery, The 2nd Affiliated Hospital of Xi an Jiaotong University, Xi an 710004, China
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 20:754-6. 2004
    ..To explore the effect of hypertonic saline on the erythrocyte adherence function and bacterial infection of hemorrhagic shock rabbits...
  36. doi request reprint Notch1 regulates the growth of human colon cancers
    Yan Zhang
    Department of Reproductive Medicine, Xi an Jiaotong University, Xi an, The People s Republic of China
    Cancer 116:5207-18. 2010
    ..The aberrant activation of the Notch signaling has been associated with the development of colon cancers. However, the role of Notch1 in the pathogenesis of colon cancers is poorly understood...
  37. ncbi request reprint [Effects of Ras antisense oligoribonucleotide on multidrug resistance of pancreatic carcinoma Pc-2 cells]
    Xi Chen
    Department of General Surgery, The Second Affiliated Hospital, Xi an Jiaotong University, Xi an 710004, China
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao 27:633-6. 2005
    ..To investigate the role of Ras antisense oligoribonucleotide (ASODN) in multidrug resistance (MDR) of pancreatic carcinoma Pc-2 cells...
  38. ncbi request reprint [Protective effects of captopril against lung injury in rats with severe acute pancreatitis]
    Shun Le Li
    Department of General Surgery, Second Affiliated Hospital, Xi an Jiaotong University College of Medicine, China
    Nan Fang Yi Ke Da Xue Xue Bao 30:2742-5. 2010
    ..To investigate the protective effects of captopril against lung injury in a rat model of severe acute pancreatitis (SAP)...
  39. ncbi request reprint [Effects of alprostadil in prevention of portal vein thrombogenesis after splenectomy and devascularization: a clinical observation of 76 patients with portal hypertension]
    Jian Cang Ma
    Department of General Surgery, Second Affiliated Hospital of Xi an Jiaotong University, Xi an 710004, China
    Zhonghua Yi Xue Za Zhi 88:524-6. 2008
    ..To investigate the effects of alprostadil (Lipo PGE1) in prevention of portal vein thrombogenesis (PVT) after splenectomy for portal hypertension...
  40. ncbi request reprint [Therapeutic effects of a recombinant adeno-associated virus expressing fusion peptide NT4p53(C22)Ant on ICR mice bearing transplanted liver cancer]
    Qi Zhou
    Research Laboratory of Medical Ultrasound, Second Affiliated Hospital, School of Medicine, Xi an Jiaotong University, Xi an 710004, China
    Nan Fang Yi Ke Da Xue Xue Bao 27:1355-7. 2007
    ..To study the therapeutic effects of recombinant adeno-associated virus (rAAV) expressing fusion peptide NT4p53(C22)Ant against transplanted liver cancer in ICR mice...