Pingbo Huang

Summary

Affiliation: Clear Water Bay
Country: China

Publications

  1. ncbi Local regulation of cystic fibrosis transmembrane regulator and epithelial sodium channel in airway epithelium
    Pingbo Huang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
    Proc Am Thorac Soc 1:33-7. 2004
  2. ncbi Apical adenosine regulates basolateral Ca2+-activated potassium channels in human airway Calu-3 epithelial cells
    Dong Wang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People s Republic of China
    Am J Physiol Cell Physiol 294:C1443-53. 2008
  3. ncbi Functional coupling of Gs and CFTR is independent of their association with lipid rafts in epithelial cells
    Dong Wang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People s Republic of China
    Pflugers Arch 456:929-38. 2008
  4. ncbi A novel mechanism of control of NFκB activation and inflammation involving A2B adenosine receptors
    Ying Sun
    Division of Life Science, Hong Kong University of Science and Technology, Hong Kong, People s Republic of China
    J Cell Sci 125:4507-17. 2012
  5. ncbi Adenosine promotes IL-6 release in airway epithelia
    Ying Sun
    Department of Biology, Hong Kong University of Science and Technology, Hong Kong, People s Republic of China
    J Immunol 180:4173-81. 2008
  6. ncbi Regulation of CFTR channels by HCO(3)--sensitive soluble adenylyl cyclase in human airway epithelial cells
    Yan Wang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People s Republic of China
    Am J Physiol Cell Physiol 289:C1145-51. 2005
  7. ncbi Intracellular spatial control of fluorescent magnetic nanoparticles
    Jinhao Gao
    Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China
    J Am Chem Soc 130:3710-1. 2008
  8. ncbi Voltage-dependent anion channel-1 (VDAC-1) contributes to ATP release and cell volume regulation in murine cells
    Seiko F Okada
    Cystic Fibrosis Pulmonary Research and Treatment Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Gen Physiol 124:513-26. 2004
  9. ncbi Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium
    Anthony P Barnes
    Department of Cell and Developmental Biology and Cystic Fibrosis Pulmonary Research and Treatment Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    J Biol Chem 280:7997-8003. 2005

Collaborators

Detail Information

Publications9

  1. ncbi Local regulation of cystic fibrosis transmembrane regulator and epithelial sodium channel in airway epithelium
    Pingbo Huang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
    Proc Am Thorac Soc 1:33-7. 2004
    ..Inhibition of ENaC by P2Y2 receptors appears to be mediated by phospholipase C-beta3, possibly through an effect on the levels of phosphatidylinositol 4,5-bisphosphonate in the apical membrane...
  2. ncbi Apical adenosine regulates basolateral Ca2+-activated potassium channels in human airway Calu-3 epithelial cells
    Dong Wang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People s Republic of China
    Am J Physiol Cell Physiol 294:C1443-53. 2008
    ..Our findings provide novel mechanistic insights into the regulation of anion section by adenosine, a key player in the airway surface liquid homeostasis and mucociliary clearance...
  3. ncbi Functional coupling of Gs and CFTR is independent of their association with lipid rafts in epithelial cells
    Dong Wang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People s Republic of China
    Pflugers Arch 456:929-38. 2008
    ..Our data suggest that GPCR-mediated signaling maintain their integrity after lipid raft disruption in Calu-3 and T84 epithelial cells and cast doubts on the role of lipid rafts as signaling platforms in GPCR-mediated signaling...
  4. ncbi A novel mechanism of control of NFκB activation and inflammation involving A2B adenosine receptors
    Ying Sun
    Division of Life Science, Hong Kong University of Science and Technology, Hong Kong, People s Republic of China
    J Cell Sci 125:4507-17. 2012
    ..Our findings unveil a surprising function for the A(2B)AR, and provide a novel mechanistic insight into the control of the NFκB pathway and inflammation...
  5. ncbi Adenosine promotes IL-6 release in airway epithelia
    Ying Sun
    Department of Biology, Hong Kong University of Science and Technology, Hong Kong, People s Republic of China
    J Immunol 180:4173-81. 2008
    ..Our findings provide a possible molecular link between extracellular adenosine elevation and lung inflammation and fibrosis...
  6. ncbi Regulation of CFTR channels by HCO(3)--sensitive soluble adenylyl cyclase in human airway epithelial cells
    Yan Wang
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People s Republic of China
    Am J Physiol Cell Physiol 289:C1145-51. 2005
    ....
  7. ncbi Intracellular spatial control of fluorescent magnetic nanoparticles
    Jinhao Gao
    Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China
    J Am Chem Soc 130:3710-1. 2008
    ..Confocal images indicate that the uptaken nanoparticles can be manipulated using a small magnet. The successful intracellular manipulation of magnetic nanoparticles may offer a new strategy for studying polarized cells...
  8. ncbi Voltage-dependent anion channel-1 (VDAC-1) contributes to ATP release and cell volume regulation in murine cells
    Seiko F Okada
    Cystic Fibrosis Pulmonary Research and Treatment Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Gen Physiol 124:513-26. 2004
    ..However, the observation that VDAC-1 knockout cells released a significant amount of ATP suggests that other molecules also play a role in this function...
  9. ncbi Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium
    Anthony P Barnes
    Department of Cell and Developmental Biology and Cystic Fibrosis Pulmonary Research and Treatment Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    J Biol Chem 280:7997-8003. 2005
    ..These findings underscore the concept that subcellular localization of individual PDE isozymes is an important mechanism for confining cAMP signaling to functional domains within cells...