Ava J Y Guo

Summary

Affiliation: Clear Water Bay
Country: China

Publications

  1. pmc Stimulation of Apolipoprotein A-IV expression in Caco-2/TC7 enterocytes and reduction of triglyceride formation in 3T3-L1 adipocytes by potential anti-obesity Chinese herbal medicines
    Ava Jiangyang Guo
    Macao Institute for Applied Research in Medicine and Health MUST Foundation, Avenida Wai Long, Taipa, Macao SAR, PR China
    Chin Med 4:5. 2009
  2. doi request reprint Galangin, a flavonol derived from Rhizoma Alpiniae Officinarum, inhibits acetylcholinesterase activity in vitro
    Ava J Y Guo
    Department of Biology and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong SAR, China
    Chem Biol Interact 187:246-8. 2010
  3. pmc The assembly of proline-rich membrane anchor (PRiMA)-linked acetylcholinesterase enzyme: glycosylation is required for enzymatic activity but not for oligomerization
    Vicky P Chen
    Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Hong Kong SAR, China
    J Biol Chem 286:32948-61. 2011
  4. doi request reprint Flavonoids from Radix Astragali induce the expression of erythropoietin in cultured cells: a signaling mediated via the accumulation of hypoxia-inducible factor-1α
    Ken Y Z Zheng
    Section of Marine Ecology and Biotechnology, Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, China
    J Agric Food Chem 59:1697-704. 2011
  5. doi request reprint PRiMA directs a restricted localization of tetrameric AChE at synapses
    Heidi Q Xie
    Department of Biology and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, China
    Chem Biol Interact 187:78-83. 2010
  6. doi request reprint Expression and Localization of PRiMA-linked globular form acetylcholinesterase in vertebrate neuromuscular junctions
    Karl W K Tsim
    Department of Biology, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, SAR, China
    J Mol Neurosci 40:40-6. 2010
  7. doi request reprint Hibifolin, a flavonol glycoside, prevents beta-amyloid-induced neurotoxicity in cultured cortical neurons
    Judy T T Zhu
    Department of Biology and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay Road, Kowloon, Hong Kong SAR, China
    Neurosci Lett 461:172-6. 2009
  8. doi request reprint The expression of erythropoietin triggered by danggui buxue tang, a Chinese herbal decoction prepared from radix Astragali and radix Angelicae Sinensis, is mediated by the hypoxia-inducible factor in cultured HEK293T cells
    Ken Y Z Zheng
    Department of Biology and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, China
    J Ethnopharmacol 132:259-67. 2010
  9. doi request reprint A new variant of proline-rich membrane anchor (PRiMA) of acetylcholinesterase in chicken: expression in different muscle fiber types
    Mokka K W Mok
    Department of Biology and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, SAR, China
    Neurosci Lett 461:202-6. 2009
  10. doi request reprint Quality evaluation of Rhizoma Belamcandae (Belamcanda chinensis (L.) DC.) by using high-performance liquid chromatography coupled with diode array detector and mass spectrometry
    Jun Li
    Center for Chinese Medicine and Department of Biology, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, China
    J Chromatogr A 1216:2071-8. 2009

Collaborators

Detail Information

Publications10

  1. pmc Stimulation of Apolipoprotein A-IV expression in Caco-2/TC7 enterocytes and reduction of triglyceride formation in 3T3-L1 adipocytes by potential anti-obesity Chinese herbal medicines
    Ava Jiangyang Guo
    Macao Institute for Applied Research in Medicine and Health MUST Foundation, Avenida Wai Long, Taipa, Macao SAR, PR China
    Chin Med 4:5. 2009
    ..CONCLUSION: The results suggest that Rhizoma Alistmatis and Radix Angelica Sinensis may have potential anti-obesity effects as they stimulate ApoA-IV transcription and reduce triglyceride formation...
  2. doi request reprint Galangin, a flavonol derived from Rhizoma Alpiniae Officinarum, inhibits acetylcholinesterase activity in vitro
    Ava J Y Guo
    Department of Biology and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong SAR, China
    Chem Biol Interact 187:246-8. 2010
    ..The results suggest that flavonoids could be potential candidates for further development of new drugs against AD...
  3. pmc The assembly of proline-rich membrane anchor (PRiMA)-linked acetylcholinesterase enzyme: glycosylation is required for enzymatic activity but not for oligomerization
    Vicky P Chen
    Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Hong Kong SAR, China
    J Biol Chem 286:32948-61. 2011
    ..This glycan-depleted enzyme was assembled in endoplasmic reticulum but was not transported to Golgi apparatus or plasma membrane...
  4. doi request reprint Flavonoids from Radix Astragali induce the expression of erythropoietin in cultured cells: a signaling mediated via the accumulation of hypoxia-inducible factor-1α
    Ken Y Z Zheng
    Section of Marine Ecology and Biotechnology, Division of Life Science and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, China
    J Agric Food Chem 59:1697-704. 2011
    ..The regulation of HIF-1α therefore could account for the activation of EPO expression mediated by the RA flavonoids. The current results therefore reveal the function of this herb in enhancing hematopoietic functions...
  5. doi request reprint PRiMA directs a restricted localization of tetrameric AChE at synapses
    Heidi Q Xie
    Department of Biology and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, China
    Chem Biol Interact 187:78-83. 2010
    ..The restricted localizations suggest that the raft association of PRiMA-linked AChE could account for its synaptic localization and function...
  6. doi request reprint Expression and Localization of PRiMA-linked globular form acetylcholinesterase in vertebrate neuromuscular junctions
    Karl W K Tsim
    Department of Biology, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, SAR, China
    J Mol Neurosci 40:40-6. 2010
    ..These findings suggest that the restricted localization of PRiMA-linked G4 AChE at the nmjs could be contributed by the pre-synaptic motor neuron and/or the post-synaptic muscle fiber...
  7. doi request reprint Hibifolin, a flavonol glycoside, prevents beta-amyloid-induced neurotoxicity in cultured cortical neurons
    Judy T T Zhu
    Department of Biology and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay Road, Kowloon, Hong Kong SAR, China
    Neurosci Lett 461:172-6. 2009
    ..These results therefore provided the first evidence that hibifolin protected neurons against A beta-induced apoptosis and stimulated Akt activation, which would be useful in developing potential drugs or food supplements for treating AD...
  8. doi request reprint The expression of erythropoietin triggered by danggui buxue tang, a Chinese herbal decoction prepared from radix Astragali and radix Angelicae Sinensis, is mediated by the hypoxia-inducible factor in cultured HEK293T cells
    Ken Y Z Zheng
    Department of Biology and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, China
    J Ethnopharmacol 132:259-67. 2010
    ..Pharmacological results indicate that DBT can stimulate the production of erythropoietin (EPO), a specific hematopoietic growth factor, in cultured cells...
  9. doi request reprint A new variant of proline-rich membrane anchor (PRiMA) of acetylcholinesterase in chicken: expression in different muscle fiber types
    Mokka K W Mok
    Department of Biology and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, SAR, China
    Neurosci Lett 461:202-6. 2009
    ..This finding suggests that the muscle fiber type-specific expression of G(4) AChE in chicken could be a result of the different expression pattern of PRiMA in fast- and slow-twitch muscles...
  10. doi request reprint Quality evaluation of Rhizoma Belamcandae (Belamcanda chinensis (L.) DC.) by using high-performance liquid chromatography coupled with diode array detector and mass spectrometry
    Jun Li
    Center for Chinese Medicine and Department of Biology, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, China
    J Chromatogr A 1216:2071-8. 2009
    ..This developed method by having a combination of chromatographic fingerprint and quantification analysis could be applied to the quality control of Rhizoma Belamcandae...