R S S Wu

Summary

Affiliation: City University of Hong Kong
Country: China

Publications

  1. ncbi Aquatic hypoxia is an disrupter and impairs fish reproduction
    Rudolf S S Wu
    Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong
    Environ Sci Technol 37:1137-41. 2003
  2. doi Ethoxyresorufin-O-deethylase enzyme activities and accumulation of secondary/tertiary lysosomes in rabbitfish Siganus oramin as biomarkers for xenobiotic exposures
    James K H Fang
    State Key Laboratory in Marine Pollution and Department of Biology and Chemistry, City University of Hong Kong, Kowloon, Hong Kong
    Sci Total Environ 408:4833-40. 2010
  3. pmc Cloning and expression analysis of two distinct HIF-alpha isoforms--gcHIF-1alpha and gcHIF-4alpha--from the hypoxia-tolerant grass carp, Ctenopharyngodon idellus
    Sheran H W Law
    Department of Biology and Chemistry, City University of Hong Kong, Kowloon Tong, People s Republic of China
    BMC Mol Biol 7:15. 2006
  4. ncbi Evaluation of biomarkers of exposure and effect in juvenile areolated grouper (Epinephelus areolatus) on foodborne exposure to benzo[a]pyrene
    Rudolf S S Wu
    Centre for Coastal Pollution and Conservation, City University of Hong Kong, Kowloon, Hong Kong SAR, People s Republic of China
    Environ Toxicol Chem 22:1568-73. 2003
  5. ncbi Tolerance to, and avoidance of, hypoxia by the penaeid shrimp (Metapenaeus ensis)
    R S S Wu
    Centre for Coastal Pollution and Conservation, City University of Hong Kong, SAR, China
    Environ Pollut 118:351-5. 2002
  6. ncbi Induction, adaptation and recovery of biological responses: implications for environmental monitoring
    Rudolf S S Wu
    Centre for Coastal Pollution and Conservation and Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong
    Mar Pollut Bull 51:623-34. 2005
  7. ncbi Removal of phosphate from water by a highly selective La(III)-chelex resin
    Rudolf S S Wu
    Centre for Coastal Pollution and Conservation, Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China
    Chemosphere 69:289-94. 2007
  8. ncbi Hypoxia: from molecular responses to ecosystem responses
    Rudolf S S Wu
    Department of Biology and Chemistry, City University of Hong Kong, Kowloon
    Mar Pollut Bull 45:35-45. 2002
  9. ncbi An 'artificial mussel' for monitoring heavy metals in marine environments
    Rudolf S S Wu
    Centre for Coastal Pollution and Conservation, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China
    Environ Pollut 145:104-10. 2007
  10. ncbi Spatio-temporal changes of marine macrobenthic community in sub-tropical waters upon recovery from eutrophication. I. Sediment quality and community structure
    P K S Shin
    Department of Biology and Chemistry, City University of Hong Kong, Hong Kong
    Mar Pollut Bull 56:282-96. 2008

Collaborators

Detail Information

Publications65

  1. ncbi Aquatic hypoxia is an disrupter and impairs fish reproduction
    Rudolf S S Wu
    Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong
    Environ Sci Technol 37:1137-41. 2003
    ..Since aquatic hypoxia commonly occurs over thousands of square kilometers in aquatic systems worldwide, our results imply that endocrine disruption and reproductive impairment in fish may be a widespread environmental problem...
  2. doi Ethoxyresorufin-O-deethylase enzyme activities and accumulation of secondary/tertiary lysosomes in rabbitfish Siganus oramin as biomarkers for xenobiotic exposures
    James K H Fang
    State Key Laboratory in Marine Pollution and Department of Biology and Chemistry, City University of Hong Kong, Kowloon, Hong Kong
    Sci Total Environ 408:4833-40. 2010
    ..oramin was recommended as an effective biomarker of xenobiotic exposures and toxic effects for use in coastal pollution monitoring programmes...
  3. pmc Cloning and expression analysis of two distinct HIF-alpha isoforms--gcHIF-1alpha and gcHIF-4alpha--from the hypoxia-tolerant grass carp, Ctenopharyngodon idellus
    Sheran H W Law
    Department of Biology and Chemistry, City University of Hong Kong, Kowloon Tong, People s Republic of China
    BMC Mol Biol 7:15. 2006
    ..Hypoxia-inducible factors (HIFs) are involved in adaptive and survival responses to hypoxic stress in mammals. In fish, very little is known about the functions of HIFs...
  4. ncbi Evaluation of biomarkers of exposure and effect in juvenile areolated grouper (Epinephelus areolatus) on foodborne exposure to benzo[a]pyrene
    Rudolf S S Wu
    Centre for Coastal Pollution and Conservation, City University of Hong Kong, Kowloon, Hong Kong SAR, People s Republic of China
    Environ Toxicol Chem 22:1568-73. 2003
    ..Our data also suggest that these hormonal disturbances are not persistent and that normal hormonal levels can be restored soon after contamination is abated...
  5. ncbi Tolerance to, and avoidance of, hypoxia by the penaeid shrimp (Metapenaeus ensis)
    R S S Wu
    Centre for Coastal Pollution and Conservation, City University of Hong Kong, SAR, China
    Environ Pollut 118:351-5. 2002
    ..ensis were able to avoid hypoxic areas and move to oxygenated water. M. ensis appeared to be sensitive to hypoxia, and their ability to detect and avoid hypoxia may enhance their survival in habitats where hypoxia may occur...
  6. ncbi Induction, adaptation and recovery of biological responses: implications for environmental monitoring
    Rudolf S S Wu
    Centre for Coastal Pollution and Conservation and Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong
    Mar Pollut Bull 51:623-34. 2005
    ....
  7. ncbi Removal of phosphate from water by a highly selective La(III)-chelex resin
    Rudolf S S Wu
    Centre for Coastal Pollution and Conservation, Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China
    Chemosphere 69:289-94. 2007
    ..1M) such as chloride and sulfate. The La-chelex resin was also able to efficiently remove phosphate from seawater to <0.1mg-Pl(-1), and regenerated for reuse by removing the sorbed phosphate by eluting with 6M HCl...
  8. ncbi Hypoxia: from molecular responses to ecosystem responses
    Rudolf S S Wu
    Department of Biology and Chemistry, City University of Hong Kong, Kowloon
    Mar Pollut Bull 45:35-45. 2002
    ..The inability to isolate effects of hypoxia from interactions of these compounding factors makes it difficult to attribute many of the observed ecological effects to hypoxia...
  9. ncbi An 'artificial mussel' for monitoring heavy metals in marine environments
    Rudolf S S Wu
    Centre for Coastal Pollution and Conservation, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China
    Environ Pollut 145:104-10. 2007
    ....
  10. ncbi Spatio-temporal changes of marine macrobenthic community in sub-tropical waters upon recovery from eutrophication. I. Sediment quality and community structure
    P K S Shin
    Department of Biology and Chemistry, City University of Hong Kong, Hong Kong
    Mar Pollut Bull 56:282-96. 2008
    ..This suggested that a detectable recovery of benthic community in the harbour may take at least three years and a complete recovery may even take longer duration...
  11. ncbi Risk to breeding success of fish-eating Ardeids due to persistent organic contaminants in Hong Kong: evidence from organochlorine compounds in eggs
    D W Connell
    Centre for Coastal Pollution and Conservation, Department of Biology and Chemistry, City University of Hong Kong, Tate Chee Avenue, Kowloon, Hong Kong
    Water Res 37:459-67. 2003
    ..9% with the Little Egret. These results indicate that the DDTs in eggs would be expected to be associated with adverse effects on the survival of young of both species, particularly the Little Egret...
  12. doi Influences of ammonia-nitrogen and dissolved oxygen on lysosomal integrity in green-lipped mussel Perna viridis: laboratory evaluation and field validation in Victoria Harbour, Hong Kong
    J K H Fang
    Department of Biology and Chemistry, City University of Hong Kong, Hong Kong
    Mar Pollut Bull 56:2052-8. 2008
    ....
  13. ncbi Development of a marine fish model for studying in vivo molecular responses in ecotoxicology
    R Y C Kong
    Centre for Coastal Pollution and Conservation, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong
    Aquat Toxicol 86:131-41. 2008
    ..melastigma (p<0.05). Overall, the results suggest that O. melastigma can serve as a model marine fish for assessing multiple in vivo molecular responses to stresses in the marine environment...
  14. doi Metal concentrations in green-lipped mussels (Perna viridis) and rabbitfish (Siganus oramin) from Victoria Harbour, Hong Kong after pollution abatement
    J K H Fang
    Centre for Coastal Pollution and Conservation and Department of Biology and Chemistry, City University of Hong Kong, 83, Tat Chee Avenue, Kowloon, Hong Kong
    Mar Pollut Bull 56:1486-91. 2008
  15. doi Power analysis for biomarkers in mussels for use in coastal pollution monitoring
    J K H Fang
    Centre for Coastal Pollution and Conservation, Department of Biology and Chemistry, City University of Hong Kong, 83, Tat Chee Avenue, Kowloon, Hong Kong
    Mar Pollut Bull 58:1152-8. 2009
    ..Natural variability of lysosomal NRRT and MN frequency was significantly greater than CI and/or GSI in mussels, rejecting the general belief in the greater variability of higher-tiered hierarchical biomarkers...
  16. doi Seasonality of bioaccumulation of trace organics and lysosomal integrity in green-lipped mussel Perna viridis
    James K H Fang
    State Key Laboratory of Marine Pollution and Department of Biology and Chemistry, City University of Hong Kong, Kowloon, Hong Kong
    Sci Total Environ 408:1458-65. 2010
    ..viridis, which was recommended as a routine screening biomarker in monitoring of harbour water quality across seasons...
  17. ncbi Application of the comet and micronucleus assays to the detection of B[a]P genotoxicity in haemocytes of the green-lipped mussel (Perna viridis)
    W H L Siu
    Department of Biology and Chemistry, Centre for Coastal Pollution and Conservation, City University of Hong Kong, Kowloon, Hong Kong SAR, PR China
    Aquat Toxicol 66:381-92. 2004
    ..We suggest that DNA strand breakage and micronucleus formation in mussel haemocytes can potentially be used as convenient biomarkers of exposure to genotoxicants in the marine environment...
  18. ncbi Spatio-temporal changes of marine macrobenthic community in sub-tropical waters upon recovery from eutrophication. II. Life-history traits and feeding guilds of polychaete community
    S G Cheung
    Department of Biology and Chemistry, City University of Hong Kong, Kowloon, Hong Kong
    Mar Pollut Bull 56:297-307. 2008
    ..The implications of using life-history traits and feeding guild analyses for benthic community are discussed...
  19. ncbi Ultraviolet damages sperm mitochondrial function and membrane integrity in the sea urchin Anthocidaris crassispina
    X Y Lu
    Center for Coastal Pollution and Conservation, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, China
    Ecotoxicol Environ Saf 61:53-9. 2005
    ..Mitochondrial function of sperm may also offer a reliable ecotoxicological biomarker for predicting fertilization success in urchins...
  20. doi The use of muscle burden in rabbitfish Siganus oramin for monitoring polycyclic aromatic hydrocarbons and polychlorinated biphenyls in Victoria Harbour, Hong Kong and potential human health risk
    James K H Fang
    Centre for Coastal Pollution and Conservation, Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong
    Sci Total Environ 407:4327-32. 2009
    ..oramin were in line with the established PAH and PCB levels in sediments and/or mussels from the harbour, suggesting S. oramin can be used as a model fish species for monitoring PAHs and PCBs in the region...
  21. ncbi An updated baseline of subtropical macrobenthic communities in Hong Kong
    P K S Shin
    Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China
    Mar Pollut Bull 49:128-35. 2004
  22. ncbi Recolonization and succession of subtidal macrobenthic infauna in sediments contaminated with cadmium
    L Lu
    Center for Coastal Pollution and Conservation, City University of Hong Kong, Kowloon, Hong Kong SAR, China
    Environ Pollut 121:27-38. 2003
    ....
  23. doi Polybrominated diphenylethers (PBDEs) alter larval settlement of marine benthic polychaetes
    Cindy Lam
    Centre for Marine Environmental Research and Innovative Technology, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong, Hong Kong SAR, China
    Environ Sci Technol 44:7130-7. 2010
    ..Given the global contamination of PBDE in marine sediment, BDE 47 may potentially alter the settlement pattern of marine polychaetes and hence their benthic composition over large areas...
  24. ncbi Modeling of depuration of paralytic shellfish toxins in Chlamys nobilis and Perna viridis
    K N Yu
    Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong, Kowloon, Hong Kong
    Mar Pollut Bull 50:474-9. 2005
  25. ncbi Whole-mount in situ TUNEL method revealed ectopic pattern of apoptosis in cadmium treated naupliar larvae of barnacle (Balanus amphitrite Darwin)
    Shuk Han Cheng
    Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Hong Kong, China
    Chemosphere 55:1387-94. 2004
    ..Significant increases in apoptosis were detected in the non-motile and dead nauplii. This study suggested that whole-mount in situ TUNEL method may be used to study increased occurrence of apoptotic cells in crustacean larvae...
  26. ncbi Cultured gill epithelial cells from tilapia (Oreochromis niloticus): a new in vitro assay for toxicants
    Bingsheng Zhou
    Center for Coastal Pollution and Conservation, Department of Biology and Chemistry, City University of Hong Kong, Kowloon, Hong Kong SAR, PR China
    Aquat Toxicol 71:61-72. 2005
    ..The results suggest that the cultured gill epithelia from seawater-adapted tilapia may serve as a simple, rapid and cost-effective tool for assessing exposure and potential effects of toxicants in marine waters...
  27. doi Measuring and monitoring persistent organic pollutants in the context of risk assessment
    Rudolf S S Wu
    Department of Biology and Chemistry, Research Centre for Coastal Pollution and Conservation, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong
    Mar Pollut Bull 57:236-44. 2008
    ....
  28. doi Induction, adaptation and recovery of lysosomal integrity in green-lipped mussel Perna viridis
    J K H Fang
    Centre for Coastal Pollution and Conservation, Department of Biology and Chemistry, City University of Hong Kong, Kowloon, Hong Kong
    Mar Pollut Bull 57:467-72. 2008
    ..viridis can serve as a good biomarker in biomonitoring, as its response is not likely to generate both false-negative and false-positive results...
  29. ncbi Risk to breeding success of Ardeids by contaminants in Hong Kong: evidence from trace metals in feathers
    D W Connell
    Centre for Coastal Pollution and Conservation, Department of Biology and Chemistry, City University of Hong Kong, People s Republic of China
    Ecotoxicology 11:49-59. 2002
    ..3-1.2 microg/g) and Mai Po Village (0.0-1.4 microg/g). The evidence for the effects of lead and cadmium was limited but suggested there may possibly be adverse effects with lead but not cadmium...
  30. ncbi Molecular cloning and characterization of a hypoxia-responsive CITED3 cDNA from grass carp
    P K S Ng
    Department of Biology and Chemistry and Centre for Coastal Pollution and Conservation, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon Tong, Hong Kong, PR China
    Comp Biochem Physiol B Biochem Mol Biol 136:163-72. 2003
    ..Hypoxic induction was also observed in heart, albeit at a lower level. This is the first report on the isolation of a hypoxia-responsive CITED3 gene from fish...
  31. ncbi Cloning of the HSP70 gene in barnacle larvae and its expression under hypoxic conditions
    S H Cheng
    Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong
    Mar Pollut Bull 46:665-71. 2003
  32. ncbi Spatial and temporal variations of mercury in sediments from Victoria Harbour, Hong Kong
    Jian Bo Shi
    Department of Civil and Structural Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong
    Mar Pollut Bull 54:480-5. 2007
  33. ncbi Uptake and depuration of paralytic shellfish toxins in the green-lipped mussel, Perna viridis: a dynamic model
    Ashley M Y Li
    Department of Biology and Chemistry, City University of Hong Kong, Kowloon, Hong Kong, People s Republic of China
    Environ Toxicol Chem 24:129-35. 2005
    ..The biokinetic model allows a quantitative prediction of C2 toxins in whole ussel as well as individual tissue compartments based on the density estimates and toxin load of dinoflagellate cells in the surrounding waters over time...
  34. ncbi Physiological and cytological responses of the marine diatom Skeletonema costatum to 2,4-dichlorophenol
    Shao Yang
    Department of Biology and Chemistry and Centre for Coastal Pollution and Conservation, City University of Hong Kong, Tat Chee Avenue, Kowloon, Special Administrative Region, Hong Kong, China
    Aquat Toxicol 60:33-41. 2002
    ..The observed growth inhibition in S. costatum caused by 2,4-DCP was associated with an increase in energy storage and inhibition of protein synthesis, as indicated by a reduction in RNA/DNA ratio...
  35. ncbi Rapid detection of six types of bacterial pathogens in marine waters by multiplex PCR
    R Y C Kong
    Department of Biology and Chemistry, Center of Coastal Pollution and Conservation, City University of Hong Kong, Hong Kong Special Administrative Region
    Water Res 36:2802-12. 2002
    ....
  36. ncbi Impairment of sea urchin sperm quality by UV-B radiation: predicting fertilization success from sperm motility
    D W T Au
    Center for Coastal Pollution and Conservation, City University of Hong Kong, Kowloon
    Mar Pollut Bull 44:583-9. 2002
    ..678 + 90.202/[1 + exp(82.83 - x)/10.27)] (r(2) = 0.95). Thus, impairment of sperm motility of sea urchin, as measured by the CASA method, can be used to predict reproductive success and ecological effects...
  37. ncbi Aquatic hypoxia is a teratogen and affects fish embryonic development
    Eva H H Shang
    Centre for Coastal Pollution and Conservation and Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong SAR, People s Republic of China
    Environ Sci Technol 38:4763-7. 2004
    ..Overall, our results imply that hypoxia may have a teratogenic effect on fish and delay fish embryonic development, which may subsequently impair species fitness leading to natural population decline...
  38. ncbi Relationships between tissue concentrations of paralytic shellfish toxins and antioxidative responses of clams, Ruditapes philippinarum
    Nicola M C Choi
    Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, China
    Mar Pollut Bull 52:572-8. 2006
  39. ncbi Okadaic acid, a causative toxin of diarrhetic shellfish poisoning, in green-lipped mussels Perna viridis from Hong Kong fish culture zones: method development and monitoring
    Kylie C Y Mak
    Centre for Coastal Pollution and Conservation, Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong SAR, PR China
    Mar Pollut Bull 51:1010-7. 2005
    ..0 and 131.0 ng/g wet wt., which did not exceed the generally recognized international regulatory criteria (>200 ng/g) for OA...
  40. ncbi Exposure of spermatozoa to duroquinone may impair reproduction of the common carp (Cyprinus carpio) through oxidative stress
    Bingsheng Zhou
    Center for Coastal Pollution and Conservation, City University of Hong Kong, Kowloon, PR China
    Aquat Toxicol 77:136-42. 2006
    ..The overall results of both our in vitro and in vivo experiments demonstrated that duroquinone can induce ROS production in spermatozoa, which may impair sperm quality and subsequently reproductive success through oxidative stress...
  41. ncbi Hypoxia affects sex differentiation and development, leading to a male-dominated population in zebrafish (Danio rerio)
    Eva H H Shang
    Centre for Coastal Pollution and Conservation, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, SAR
    Environ Sci Technol 40:3118-22. 2006
    ..The male-dominated populations caused by hypoxia will have reduced reproductive success, thereby threatening the sustainability of natural fish populations...
  42. doi A whole life cycle assessment on effects of waterborne PBDEs on gene expression profile along the brain-pituitary-gonad axis and in the liver of zebrafish
    X B Han
    Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, Hong Kong
    Mar Pollut Bull 63:160-5. 2011
    ..The observed disruption of GnRH and GtHs can be further related to the subsequent disruption in both levels and balance sex steroid hormones...
  43. ncbi Isolation, characterization and expression analysis of a hypoxia-responsive glucose transporter gene from the grass carp, Ctenopharyngodon idellus
    Ziping Zhang
    Department of Biology and Chemistry, City University of Hong Kong, Kowloon Tong, Hong Kong Special Administrative Region, People s Republic of China
    Eur J Biochem 270:3010-7. 2003
    ..Up-regulated expression by hypoxia was also evident in eye and gill, but differential patterns of expression were observed. Low expression levels detected in brain, heart, liver and muscle were not responsive to hypoxic stress...
  44. ncbi UV-B damages eyes of barnacle larvae and impairs their photoresponses and settlement success
    W L Chiang
    Centre for Coastal Pollution and Conservation, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong
    Environ Sci Technol 37:1089-92. 2003
    ..The fact that enhanced UV-B radiation can induce ocular damage and subsequent phototactic impairment in barnacle larvae suggests that UV-B may also cause similar damage to other zooplankton species...
  45. ncbi Paralytic shellfish toxins in green-lipped mussels, Perna viridis, in Hong Kong
    Kylie C Y Mak
    Centre for Coastal Pollution and Conservation, Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong
    Mar Pollut Bull 46:258-63. 2003
  46. doi Effects of fifteen PBDE metabolites, DE71, DE79 and TBBPA on steroidogenesis in the H295R cell line
    Renfang Song
    Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong
    Chemosphere 71:1888-94. 2008
    ..However, none of the compounds affected sex hormone production at the concentrations tested. Generally, OH-BDEs had a much stronger ability to affect steroidogenic gene expression than MeO-BDEs...
  47. pmc Identification of a DNA methyltransferase gene carried on a pathogenicity island-like element (VPAI) in Vibrio parahaemolyticus and its prevalence among clinical and environmental isolates
    Hui zhen Wang
    Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon Tong, Kowloon, Hong Kong SAR, China
    Appl Environ Microbiol 72:4455-60. 2006
    ..parahaemolyticus MTase gene was shown by PCR to be prevalent (>98%) in pandemic thermostable direct hemolysin gene-positive isolates, which suggests that VPAI may confer unique virulence traits to pandemic strains of V. parahaemolyticus...
  48. ncbi Solid-phase extraction-fluorimetric high performance liquid chromatographic determination of domoic acid in natural seawater mediated by an amorphous titania sorbent
    Ivy O M Chan
    Centre for Coastal Pollution and Conservation, Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, China
    Anal Chim Acta 583:111-7. 2007
    ..This titania SPE technique should also be applicable to the pre-concentration of other polar carboxylate- and phosphonate-containing biomolecules and pharmaceuticals in complex and interfering environmental sample matrices...
  49. ncbi Biodegradation and enzymatic responses in the marine diatom Skeletonema costatum upon exposure to 2,4-dichlorophenol
    Shao Yang
    Department of Biology and Chemistry, Centre for Coastal Pollution and Conservation, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong Special Administrative Region, Hong Kong, China
    Aquat Toxicol 59:191-200. 2002
    ..The inhibition of glutathione synthesis enhanced the toxicity of 2,4-DCP. These results suggest that glutathione conjugation was one of the principal mechanisms involved in the degradation of 2,4-DCP in this diatom...
  50. doi Rapid magnetic-mediated solid-phase extraction and pre-concentration of selected endocrine disrupting chemicals in natural waters by poly(divinylbenzene-co-methacrylic acid) coated Fe3O4 core-shell magnetite microspheres for their liquid chromatography-ta
    Qingling Li
    Department of Biology and Chemistry, Centre of Coastal Pollution and Conservation, City University of Hong Kong, Tat Chee Ave, Kowloon, Hong Kong SAR, China
    J Chromatogr A 1217:1219-26. 2010
    ..05, n=3). This work demonstrates the usefulness of MM-SPE-MP in the rapid and highly sensitive monitoring of trace organic contaminants in natural waters...
  51. ncbi Hypoxia induces the activation of human hepatic stellate cells LX-2 through TGF-beta signaling pathway
    Yue Feng Shi
    Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, China
    FEBS Lett 581:203-10. 2007
    ..Gene expression profiles of LX-2 cells induced by hypoxia were obtained by using cDNA microarray technique...
  52. ncbi Effects of PCBs and MeSO2-PCBs on adrenocortical steroidogenesis in H295R human adrenocortical carcinoma cells
    Yan Xu
    Department of Biology and Chemistry, Centre for Coastal Pollution and Conservation, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong SAR, China
    Chemosphere 63:772-84. 2006
    ..Overall, these findings suggest that PCBs and PCB metabolites can affect regulation of adrenocortical steroidogenesis...
  53. ncbi Application of solid phase microextraction in the determination of paralytic shellfish poisoning toxins
    Ivy O M Chan
    Centre for Coastal Pollution and Conservation, Department of Biology and Chemistry, City University of Hong Kong, Kowloon, Hong Kong SAR, China
    Analyst 130:1524-9. 2005
    ..However, serious interference was observed when this technique was applied to saline water samples. This is probably due to competition of sodium ions with the cationic STX for absorption into the SPME stationary phase...
  54. doi Modulation of steroidogenesis by coastal waters and sewage effluents of Hong Kong, China, using the H295R assay
    Tannia Gracia
    Department of Zoology, National Food Safety and Toxicology Center, Center for Integrative Toxicology, Michigan State University, East Lansing, MI 48824, USA
    Environ Sci Pollut Res Int 15:332-43. 2008
    ..After exposing H295R cells to extracts of water, the expression of four steroidogenic genes and the production of three steroid hormones were measured...
  55. ncbi Primary cultured cells as sensitive in vitro model for assessment of toxicants--comparison to hepatocytes and gill epithelia
    Bingsheng Zhou
    State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, PR China
    Aquat Toxicol 80:109-18. 2006
    ....
  56. ncbi Comparative effects of the blue green algae Nodularia spumigena and a lysed extract on detoxification and antioxidant enzymes in the green lipped mussel (Perna viridis)
    Warren R Davies
    Department of Biotechnology and Environmental Biology, RMIT University, Melbourne, Victoria, Australia
    Mar Pollut Bull 51:1026-33. 2005
    ..spumigena cell densities decreased GSH and increased GST and lipid peroxidation (LPO) in mussels. Findings also suggest that at different stages of a toxic bloom, exposure may result in toxic stress to specific organs in the mussel...
  57. ncbi Quantitative RT-PCR methods for evaluating toxicant-induced effects on steroidogenesis using the H295R cell line
    Xiaowei Zhang
    Department of Zoology, National Food Safety and Toxicology Center, Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan 48824, USA
    Environ Sci Technol 39:2777-85. 2005
    ..Overall, our findings demonstrated that the present assay can facilitate the development of compound-specific response profiles, and will provide a sensitive and integrative screen for the effects of chemicals on steroidogenesis...
  58. ncbi Induction of oxidative stress and apoptosis by PFOS and PFOA in primary cultured hepatocytes of freshwater tilapia (Oreochromis niloticus)
    Chunsheng Liu
    State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, The Chinese Academy of Sciences, Wuhan 430072, PR China
    Aquat Toxicol 82:135-43. 2007
    ..The overall results demonstrated that PFOS and PFOA are able to produce oxidative stress and induce apoptosis with involvement of caspases in primary cultured tilapia hepatocytes...
  59. ncbi Modulation of steroidogenic gene expression and hormone production of H295R cells by pharmaceuticals and other environmentally active compounds
    Tannia Gracia
    Department of Zoology, National Food Safety and Toxicology Center, Center for Integrative Toxicology, Michigan State University, East Lansing, MI 48824, USA
    Toxicol Appl Pharmacol 225:142-53. 2007
    ..Dose-response results indicated that although two chemicals may share a common mechanism of action the concentration effects observed may be significantly different...
  60. doi DE-71-induced apoptosis involving intracellular calcium and the Bax-mitochondria-caspase protease pathway in human neuroblastoma cells in vitro
    Ke Yu
    State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China
    Toxicol Sci 104:341-51. 2008
    ..Overall, our results indicate that DE-71 induces the apoptosis of [Ca(2+)](i) in SK-N-SH cells via Bax insertion, Cyt c release in the mitochondria, and the caspase activation pathway...
  61. ncbi Responses of the medaka HPG axis PCR array and reproduction to prochloraz and ketoconazole
    Xiaowei Zhang
    Department of Zoology, Michigan State University, East Lansing, Michigan, USA
    Environ Sci Technol 42:6762-9. 2008
    ..Furthermore, the ecologically relevant end point, fecundity was log-log related to mRNA level of six genes in livers of females...
  62. ncbi Effects of tributyltin on the energy metabolism of pen shell (Atrina pectinata japonica)
    Suguru Inoue
    Laboratory of Fisheries Environmental Science, Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Hakozaki 6 10 1, Higashi ku, Fukuoka 812 8581, Japan
    Chemosphere 66:1226-9. 2007
    ..Our results suggest that the energy metabolism of pen shell is disrupted by exposure to TBT...
  63. doi Field validation, in Scotland and Iceland, of the artificial mussel for monitoring trace metals in temperate seas
    Kenneth M Y Leung
    Institute of Biomedical and Life Sciences, Graham Kerr Building, University of Glasgow, Glasgow G12 8QQ, UK
    Mar Pollut Bull 57:790-800. 2008
    ....
  64. doi Developmental toxicity and alteration of gene expression in zebrafish embryos exposed to PFOS
    Xiongjie Shi
    State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China
    Toxicol Appl Pharmacol 230:23-32. 2008
    ....
  65. ncbi The H295R system for evaluation of endocrine-disrupting effects
    Tannia Gracia
    Department of Zoology, 218C National Food Safety and Toxicology Center, Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan 48824 1311, USA
    Ecotoxicol Environ Saf 65:293-305. 2006
    ....