Research Topics
| B K ChowSummaryCountry: China Publications
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Detail Information
Publications
Molecular evolution of vertebrate VIP receptors and functional characterization of a VIP receptor from goldfish Carassius auratusB K Chow
Department of Zoology, The University of Hong Kong, Hong Kong
Gen Comp Endocrinol 105:176-85. 1997..Characterization of the VIP receptors in lower vertebrates should enhance our understanding of the molecular evolution and physiology of VIP in vertebrates...
Structural and functional identification of the pituitary adenylate cyclase-activating polypeptide receptor VPAC2 from the frog Rana tigrina rugulosaR L Hoo
Department of Zoology, University of Hong Kong, Pokfulam Road, Hong Kong, China
J Mol Endocrinol 27:229-38. 2001....
Interplay of pituitary adenylate cyclase-activating polypeptide with a silencer element to regulate the upstream promoter of the human gonadotropin-releasing hormone receptor geneE S Ngan
Department of Zoology, The University of Hong Kong, Pokfulam Road, Hong Kong, SAR, China
Mol Cell Endocrinol 176:135-44. 2001....
Identification of a proglucagon cDNA from Rana tigrina rugulosa that encodes two GLP-1s and that is alternatively spliced in a tissue-specific mannerC M Yeung
Department of Zoology, University of Hong Kong, Pokfulam Road, Hong Kong
Gen Comp Endocrinol 124:144-51. 2001..These findings should enhance understanding of the proglucagon evolution, structure, and expression in vertebrates...
Steroidogenic factor-1 interacts with a gonadotrope-specific element within the first exon of the human gonadotropin-releasing hormone receptor gene to mediate gonadotrope-specific expressionE S Ngan
Department of Zoology, University of Hong Kong, Hong Kong
Endocrinology 140:2452-62. 1999..In summary, the data reported here provide conclusive evidence that SF-1 interacts with the GSE motif at position -134 within the first exon of the hGnRHR gene to mediate its cell-specific expression...
Functional segregation of the highly conserved basic motifs within the third endoloop of the human secretin receptorK Y Chan
Department of Zoology, University of Hong Kong, Hong Kong, People s Republic of China
Endocrinology 142:3926-34. 2001..Immunofluorescent staining of these mutant receptors showed that these Arg residues are responsible for surface presentation and/or receptor stability...
The shrimp FAMeT cDNA is encoded for a putative enzyme involved in the methylfarnesoate (MF) biosynthetic pathway and is temporally expressed in the eyestalk of different sexesY I Silva Gunawardene
Department of Zoology, The University of Hong Kong, Pokfulam Road, Hong Kong, People's Republic of China
Insect Biochem Mol Biol 31:1115-24. 2001..We speculate that FAMeT may be important for the regulation of eyestalk neuropeptides. This is the first extensive study on the molecular characterization, structural analysis and expression of the crustacean FAMeT...
Role of N-linked glycosylation on the function and expression of the human secretin receptorR T Pang
Department of Zoology, The University of Hong Kong, Special Administrative Region, Peoples Republic of China
Endocrinology 140:5102-11. 1999..Using an anti-c-Myc monoclonal antibody and confocal microscopy, all of the mutant receptors were found to be expressed and delivered to the plasma membrane...
The human secretin receptor gene: genomic organization and promoter characterizationP K Ho
Department of Zoology, The University of Hong Kong, SAR, PR China
FEBS Lett 455:209-14. 1999..St, Hs 746T and alphaT3-1 cells. The study of the transcriptional control of human secretin and its receptor should shed light on the pathological developments of pancreatic cancer and autism in the future...
The human gC1qR/p32 gene, C1qBP. Genomic organization and promoter analysisA J Tye
Department of Zoology, University of Hong Kong, Pokfulam, Hong Kong, China
J Biol Chem 276:17069-75. 2001..Primer extension analysis mapped three major transcription start regions. The farthest transcription start site is 49 bp upstream of the ATG translation initiation codon and is in close proximity of the specific SP1 binding site...
Real-time analysis of the activities of GnRH and GnRH analogs in alphaT3-1 cells by the Cytosensor microphysiometerS S Ng
Department of Zoology, University of Hong Kong, Pokfulam Road, Hong Kong, Republic of China
J Cell Biochem 80:304-12. 2001..This silicon-based microphysiometric system should provide new information on the structure-function studies of GnRH and is an invaluable tool for the screening of new GnRH agonists and antagonists in the future...
Glucose-dependent insulinotropic polypeptide gene expression in the stomach: revealed by a transgenic mouse study, in situ hybridization and immunohistochemical stainingC M Yeung
Department of Zoology, The University of Hong Kong, People s Republic of China
Mol Cell Endocrinol 154:161-70. 1999..Taken together, our data demonstrate for the first time that GIP is expressed in human and mouse stomach...
Functional antagonism of the human secretin receptor by a recombinant protein encoding the N-terminal ectodomain of the receptorB K Chow
Department of Zoology, The University of Hong Kong, Hong Kong
Recept Signal Transduct 7:143-50. 1997..The His-tagged recombinant HSR ectodomain may also be used for screening secretin-specific agonists and antagonists by affinity chromatography in the future...
