Affiliation: Chongqing University
Pan X, Zhang Q, Qu S, Huang S, Wang H, Mei H. Allosteric effects of ATP binding on the nucleotide-binding domain of a heterodimeric ATP-binding cassette transporter. Integr Biol (Camb). 2016;8:1158-1169 pubmed
..These findings indicate that the asymmetric ATPase sites of the heterodimeric exporter are structurally and functionally distinct. ..
Huang S, Mei H, Zhang D, Ren Y, Kevin M, Pan X. The emerging chemical patterns applied in predicting human toll-like receptor 8 agonists. Medchemcomm. 2018;9:1961-1971 pubmed publisher
Pan X, Mei H, Qu S, Huang S, Sun J, Yang L, et al
. Prediction and characterization of P-glycoprotein substrates potentially bound to different sites by emerging chemical pattern and hierarchical cluster analysis. Int J Pharm. 2016;502:61-9 pubmed publisher
..The present study demonstrates, for the first time, a successful ECP model, which can not only accurately predict P-gp substrates, but also identify their potential substrate-binding sites. ..