Kaiyong Cai

Summary

Affiliation: Chongqing University
Country: China

Publications

  1. doi Regulation of endothelial cells migration on poly(D, L-lactic acid) films immobilized with collagen gradients
    Kaiyong Cai
    Key Laboratory of Biorheological Science and Technology Chongqing University, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, PR China
    Colloids Surf B Biointerfaces 79:291-7. 2010
  2. doi Construction of microenvironment onto titanium substrates to regulate the osteoblastic differentiation of bone marrow stromal cells in vitro and osteogenesis in vivo
    Min Lai
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, People s Republic of China
    J Biomed Mater Res A 101:653-66. 2013
  3. doi Surface functionalization of titanium substrates with cecropin B to improve their cytocompatibility and reduce inflammation responses
    Dawei Xu
    Key Laboratory of Biorheological Science and Technology Chongqing University, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, PR China
    Colloids Surf B Biointerfaces 110:225-35. 2013
  4. doi Fabrication of selenium-deposited and chitosan-coated titania nanotubes with anticancer and antibacterial properties
    Xiuyong Chen
    Key Laboratory of Biorheological Science and Technology Chongqing University, Ministry of Education, Joint College of Biomedical Engineering, Chongqing University, Chongqing 400044, PR China
    Colloids Surf B Biointerfaces 103:149-57. 2013
  5. doi Regulation of the differentiation of mesenchymal stem cells in vitro and osteogenesis in vivo by microenvironmental modification of titanium alloy surfaces
    Yan Hu
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China
    Biomaterials 33:3515-28. 2012
  6. doi The use of hyaluronan to regulate protein adsorption and cell infiltration in nanofibrous scaffolds
    Linhao Li
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, Bioengineering College, Chongqing University, Chongqing 400030, China
    Biomaterials 33:3428-45. 2012
  7. doi TiO2 nanotubes as drug nanoreservoirs for the regulation of mobility and differentiation of mesenchymal stem cells
    Yan Hu
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, People s Republic of China
    Acta Biomater 8:439-48. 2012
  8. doi Electrospun poly (ɛ-caprolactone)/silk fibroin core-sheath nanofibers and their potential applications in tissue engineering and drug release
    Linhao Li
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, China
    Int J Biol Macromol 49:223-32. 2011
  9. doi Surface engineering of titanium with potassium hydroxide and its effects on the growth behavior of mesenchymal stem cells
    Kaiyong Cai
    Key Laboratory of Biorheological Science and Technology Chongqing University, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China
    Acta Biomater 6:2314-21. 2010
  10. doi Surface engineering of titanium substrates with chitosan-atorvastatin conjugate for reduced inflammation responses and improved cytocompatibility
    Daichao Xie
    Key Laboratory of Biorheological Science and Technology of Ministry of Education, Joint College of Biomedical Engineering, Chongqing University, Chongqing 400044, China
    J Biomed Mater Res A 101:2005-14. 2013

Collaborators

Detail Information

Publications30

  1. doi Regulation of endothelial cells migration on poly(D, L-lactic acid) films immobilized with collagen gradients
    Kaiyong Cai
    Key Laboratory of Biorheological Science and Technology Chongqing University, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, PR China
    Colloids Surf B Biointerfaces 79:291-7. 2010
    ..It is potentially important for understanding the controlled angiogenesis for implantation of tissue-engineered constructs...
  2. doi Construction of microenvironment onto titanium substrates to regulate the osteoblastic differentiation of bone marrow stromal cells in vitro and osteogenesis in vivo
    Min Lai
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, People s Republic of China
    J Biomed Mater Res A 101:653-66. 2013
    ..This work provides an approach to fabricate high-performance titanium-based implants with enhanced bone osseointegration...
  3. doi Surface functionalization of titanium substrates with cecropin B to improve their cytocompatibility and reduce inflammation responses
    Dawei Xu
    Key Laboratory of Biorheological Science and Technology Chongqing University, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, PR China
    Colloids Surf B Biointerfaces 110:225-35. 2013
    ..The approach presented here has great potential in the development of antibacterial titanium-based implants in clinical applications. ..
  4. doi Fabrication of selenium-deposited and chitosan-coated titania nanotubes with anticancer and antibacterial properties
    Xiuyong Chen
    Key Laboratory of Biorheological Science and Technology Chongqing University, Ministry of Education, Joint College of Biomedical Engineering, Chongqing University, Chongqing 400044, PR China
    Colloids Surf B Biointerfaces 103:149-57. 2013
    ..The approach in this study provides an alternative to fabricate anticancer and antibacterial titanium-based implants for potential clinical application...
  5. doi Regulation of the differentiation of mesenchymal stem cells in vitro and osteogenesis in vivo by microenvironmental modification of titanium alloy surfaces
    Yan Hu
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China
    Biomaterials 33:3515-28. 2012
    ..The study therefore presents an alternative to fabricate bio-functionalized Ti6Al4V-based implants for potential application in orthopedics field...
  6. doi The use of hyaluronan to regulate protein adsorption and cell infiltration in nanofibrous scaffolds
    Linhao Li
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, Bioengineering College, Chongqing University, Chongqing 400030, China
    Biomaterials 33:3428-45. 2012
    ..These findings suggest that such an HA-based nanofibrous scaffold resists protein adsorption and enhances cell infiltration, may offer possibilities to overcome the limitations of electrospinning technology...
  7. doi TiO2 nanotubes as drug nanoreservoirs for the regulation of mobility and differentiation of mesenchymal stem cells
    Yan Hu
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, People s Republic of China
    Acta Biomater 8:439-48. 2012
    ..More importantly, the system demonstrated that it was capable of promoting the osteoblastic differentiation of MSCs. This study may have potential impact on the development of bone implants for enhanced bone osseointegration...
  8. doi Electrospun poly (ɛ-caprolactone)/silk fibroin core-sheath nanofibers and their potential applications in tissue engineering and drug release
    Linhao Li
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, China
    Int J Biol Macromol 49:223-32. 2011
    ..The produced nanofibrous scaffolds with sustained drug release have potential application in tissue engineering...
  9. doi Surface engineering of titanium with potassium hydroxide and its effects on the growth behavior of mesenchymal stem cells
    Kaiyong Cai
    Key Laboratory of Biorheological Science and Technology Chongqing University, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China
    Acta Biomater 6:2314-21. 2010
    ..More importantly, our results suggest that the modified titanium substrates have great potential for inducing MSCs to differentiate into osteoblasts. The approach presented here may be exploited to fabricate titanium-based implants...
  10. doi Surface engineering of titanium substrates with chitosan-atorvastatin conjugate for reduced inflammation responses and improved cytocompatibility
    Daichao Xie
    Key Laboratory of Biorheological Science and Technology of Ministry of Education, Joint College of Biomedical Engineering, Chongqing University, Chongqing 400044, China
    J Biomed Mater Res A 101:2005-14. 2013
    ..The study thus presents an alternative to fabricate bio-functionalized titanium-based implants for further clinical application...
  11. doi Surface mediated in situ differentiation of mesenchymal stem cells on gene-functionalized titanium films fabricated by layer-by-layer technique
    Yan Hu
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China
    Biomaterials 30:3626-35. 2009
    ..The approach presented here has potential applications in the development of gene-stimulating biomaterials and implant technology...
  12. doi Improved endothelialization of NiTi alloy by VEGF functionalized nanocoating
    Weixing Shen
    Key Laboratory of Biorheological Science and Technology of Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China
    Colloids Surf B Biointerfaces 94:347-53. 2012
    ..The approach presented here affords an alternative for surface modification of NiTi implants applied as heart and vascular implant devices...
  13. doi Regulation of the behaviors of mesenchymal stem cells by surface nanostructured titanium
    Min Lai
    Key Laboratory of Biorheological Science and Technology Chongqing University, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China
    Colloids Surf B Biointerfaces 97:211-20. 2012
    ..This approach for the fabrication of surface nanostructured titanium may be exploited in the development of high performance titanium-based implants...
  14. pmc Effects of titanium nanoparticles on adhesion, migration, proliferation, and differentiation of mesenchymal stem cells
    Yanhua Hou
    Key Laboratory of Biorheological Science and Technology and Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, People s Republic of China
    Int J Nanomedicine 8:3619-30. 2013
    ..Here we report the potential impact of titanium oxide (TiO2) nanoparticles on adhesion, migration, proliferation, and differentiation of mesenchymal stem cells (MSC) from the cellular level to the molecular level in the Wistar rat...
  15. ncbi Biocompatible magnetic liposomes for temperature triggered drug delivery
    Xingwei Ding
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, PR China
    Nanoscale 4:6289-92. 2012
    ..The TSMLs are stable below 39 °C and most drugs (5-(and-6)-carboxylfluorescein: 68% and doxorubicin: 90%) release within 1 h at 42 °C. Furthermore, TSMLs could deliver the anticancer drugs into cells to induce cell apoptosis...
  16. doi Cell-specific intracellular anticancer drug delivery from mesoporous silica nanoparticles with pH sensitivity
    Zhong Luo
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, PR of China
    Adv Healthc Mater 1:321-5. 2012
    ..It demonstrates great potential for both cell-specific endocytosis and intracellular pH-responsive controlled release of drugs. A possible endocytosis pathway/mechanism of the smart controlled drug release system is proposed...
  17. ncbi [Application of layer-by-layer technique on surface engineering of gene-activated biomaterials]
    Yan Hu
    College of Bioengineering, Chongqing University, Chongqing 400044, China
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 25:738-41. 2008
    ..These are of great significance to biomaterial researches...
  18. doi Inkjet printing of laminin gradient to investigate endothelial cellular alignment
    Kaiyong Cai
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, PR China
    Colloids Surf B Biointerfaces 72:230-5. 2009
    ..It is potentially important for understanding cell alignment/ingrowth behavior for angiogenesis and implant technology including tissue-engineered structures...
  19. doi Cell-specific gene transfection from a gene-functionalized poly(d,l-lactic acid) substrate fabricated by the layer-by-layer assembly technique
    Kaiyong Cai
    College of Bioengineering, Chongqing University, Chongqing, PR China
    Angew Chem Int Ed Engl 47:7479-81. 2008
  20. doi Surface functionalization of TiO2 nanotubes with bone morphogenetic protein 2 and its synergistic effect on the differentiation of mesenchymal stem cells
    Min Lai
    Key Laboratory of Biorheological Science and Technology, Chongqing University, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, PR China
    Biomacromolecules 12:1097-105. 2011
    ..The approach presented here has potential application for the development of titanium-based implants for enhanced bone osseointegration...
  21. doi Influence of the titania nanotubes dimensions on adsorption of collagen: an experimental and computational study
    Weihu Yang
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China
    Mater Sci Eng C Mater Biol Appl 34:410-6. 2014
    ..The calculated interaction energies indicated that the TiNTs with bigger dimensions had higher interaction energies, thus leading to the higher collagen adsorption. ..
  22. doi β-Cyclodextrin conjugated magnetic nanoparticles for diazepam removal from blood
    Kaiyong Cai
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, PR China
    Chem Commun (Camb) 47:7719-21. 2011
    ..The diazepam is arrested by the conjugated β-CD and then the adsorbed diazepam is efficiently removed by an external magnetic field. These particles have potential applications in hemoperfusion or separation of other toxins and drugs...
  23. doi Influences of magnetized hydroxyapatite on the growth behaviors of osteoblasts and the mechanism from molecular dynamics simulation
    Weihu Yang
    Key Laboratory of Biorheological Science and Technology, Ministry of Education College of Bioengineering, Chongqing University, Chongqing 400044, China
    Mater Sci Eng C Mater Biol Appl 33:3753-9. 2013
    ..Nevertheless, the (211) crystal face of mHA still had a relatively higher electron density than that of HA, thus possessing better protein adsorption than that of HA, and in turn promoting the biological functions of osteoblasts. ..
  24. doi Effects of micropatterned curvature on the motility and mechanical properties of airway smooth muscle cells
    Jimin Xu
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, and Bioengineering College, Chongqing University, 174 Shapingzhengjie Street, Chongqing 400044, China
    Biochem Biophys Res Commun 415:591-6. 2011
    ..These results may provide valuable insights to understanding the heterogeneity of airway constrictions in asthma as well as the developing and functioning of other tubular organs and tissue engineering...
  25. ncbi [Preparation and cytocompatibility study of poly (epsilon-caprolactone)/silk sericin nanofibrous scaffolds]
    Haibin Li
    Key Laboratory of Biorheological Science and Technology Chongqing University, Ministry of Education, Bioengineering College, Chongqing University, Chongqing 400044, China
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 28:305-9. 2011
    ..Furthermore, the capability of hydrophile increased with the SS addition, which improved FEK4 cells adhesion and proliferation on the scaffolds...
  26. doi TGF-β1 promoted MMP-2 mediated wound healing of anterior cruciate ligament fibroblasts through NF-κB
    Yequan Wang
    Key Laboratory of Biorheological Science and Technology, Ministry of Education, Bioengineering College, Chongqing University, Chongqing, PR China
    Connect Tissue Res 52:218-25. 2011
    ..The migration process is mediated by MMP-2 and NF-κB pathway is involved in TGF-β1-mediated MMP-2 release...
  27. ncbi Biomedical nanomaterials for imaging-guided cancer therapy
    Yuran Huang
    College of Bioengineering, Chongqing University, 174 Shazheng Road, Shapingba, Chongqing, China
    Nanoscale 4:6135-49. 2012
    ..It is hoped that this review might provide new impetus to understand nanotechnology and nanomaterials employed for imaging-guided cancer therapy...
  28. ncbi Surface modification of titanium thin film with chitosan via electrostatic self-assembly technique and its influence on osteoblast growth behavior
    Kaiyong Cai
    College of Bioengineering, Chongqing University, Chongqing, P R China
    J Mater Sci Mater Med 19:499-506. 2008
    ..These results suggest that surface modification of titanium film was successfully achieved via deposition of PEI/(PSS/Chi)x layers, which is useful to enhance the biocompatibility of the titanium film...
  29. ncbi Histological study of surface modified three dimensional poly (D, L-lactic acid) scaffolds with chitosan in vivo
    Kaiyong Cai
    College of Bioengineering, Chong Qing University, Chong Qing, 400044, PR China
    J Mater Sci Mater Med 18:2017-24. 2007
    ..The histological results have shown a higher bone formation potential and better biocompatibility of chitosan-modified 3-D PDLLA scaffolds as compared with the control group scaffolds...
  30. doi Microstructure, mechanical and bio-corrosion properties of Mn-doped Mg-Zn-Ca bulk metallic glass composites
    Jingfeng Wang
    National Engineering Research Center for Magnesium Alloys, College of Materials Science and Engineering, Chongqing University, Chongqing 400044, PR China
    Mater Sci Eng C Mater Biol Appl 33:3832-8. 2013
    ..Mg68.5Zn27Ca4Mn0.5 exhibits the highest bio-corrosion resistance, biocompatibility and has desirable mechanical properties, which could suggest to be used as biomedical materials in the future...