W C S Cho


Country: China


  1. Ji X, Lu Y, Tian H, Meng X, Wei M, Cho W. Chemoresistance mechanisms of breast cancer and their countermeasures. Biomed Pharmacother. 2019;114:108800 pubmed publisher
    ..In this article, we review the mechanisms of chemoresistance in breast cancer. Furthermore, the potential therapeutic methods to overcome the resistance were discussed. ..
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    Cho W. Application of proteomics in Chinese medicine research. Am J Chin Med. 2007;35:911-22 pubmed
  3. Cho W, Chen H. Clinical efficacy of traditional Chinese medicine as a concomitant therapy for nasopharyngeal carcinoma: a systematic review and meta-analysis. Cancer Invest. 2009;27:334-44 pubmed publisher
    ..There were 16 Chinese herbs found to be commonly used across the studies. Published studies suggest that TCM is efficacious as a concomitant therapy for NPC patients. These results require confirmation with rigorously controlled trials. ..
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    Cho W. Cancer research on non-small cell lung cancer in smokers and non-smokers: snapshots from the AACR annual meeting 2009. Cancer Biol Ther. 2009;8:1309-12 pubmed
    ..This meeting report aims to provide the readers with a summary of the research highlights on NSCLC in smokers and non-smokers presented in the AACR annual meeting 2009. ..
  5. Cho W. Scientific evidence on the supportive cancer care with Chinese medicine. Zhongguo Fei Ai Za Zhi. 2010;13:190-4 pubmed publisher
  6. Pizzamiglio S, De Bortoli M, Taverna E, Signore M, Veneroni S, Cho W, et al. Expression of Iron-Related Proteins Differentiate Non-Cancerous and Cancerous Breast Tumors. Int J Mol Sci. 2017;18: pubmed publisher
    ..Our results showed an association between some iron-related proteins and the type of tumor tissue, which may provide insight in strategies for using iron chelators to treat breast cancer. ..
  7. Sin T, Wang F, Meng F, Wong S, Cho W, Siu P, et al. Implications of MicroRNAs in the Treatment of Gefitinib-Resistant Non-Small Cell Lung Cancer. Int J Mol Sci. 2016;17:237 pubmed publisher
    ..The present review aims to discuss the therapeutic capacity of miRNAs in relation to recent discoveries on EGFR-TKI resistance, including chronic drug exposure and mutations. ..
  8. Cho W. MicroRNAs: potential biomarkers for cancer diagnosis, prognosis and targets for therapy. Int J Biochem Cell Biol. 2010;42:1273-81 pubmed publisher
  9. Tosi U, Marnell C, Chang R, Cho W, Ting R, Maachani U, et al. Advances in Molecular Imaging of Locally Delivered Targeted Therapeutics for Central Nervous System Tumors. Int J Mol Sci. 2017;18: pubmed publisher
    ..In this review, we focus on the advances and the challenges to improve early cancer detection, selection of targeted therapy, and evaluation of therapeutic efficacy, brought forth by the development of these new agents. ..

More Information


  1. Liu X, Cho W. Precision medicine in immune checkpoint blockade therapy for non-small cell lung cancer. Clin Transl Med. 2017;6:7 pubmed publisher
    ..Therefore, in this era of precision medicine, there is an urgent need for predictive biomarkers to identify NSCLC patients likely to benefit from this novel therapy. ..
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    Liu X, Fu Q, Du Y, Yang Y, Cho W. MicroRNA as Regulators of Cancer Stem Cells and Chemoresistance in Colorectal Cancer. Curr Cancer Drug Targets. 2016;16:738-754 pubmed
  3. Yang Y, Du Y, Liu X, Cho W. Involvement of Non-coding RNAs in the Signaling Pathways of Colorectal Cancer. Adv Exp Med Biol. 2016;937:19-51 pubmed publisher
    ..In this chapter, we summarize the latest findings on ncRNAs, with a focus on miRNAs and lncRNAs involving in signaling networks and in the regulation of pathogenic signaling pathways in CRC. ..
  4. Cho W. Epigenetic alteration of microRNAs in feces of colorectal cancer and its clinical significance. Expert Rev Mol Diagn. 2011;11:691-4 pubmed publisher
    ..This article evaluates a recently published study investigating the usefulness of epigenetically silenced miRNAs in fecal specimens, including miR-34b/c and miR-148a, as potential markers for CRC screening and prognosis. ..
  5. Liu G, Pei F, Yang F, Li L, Amin A, Liu S, et al. Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer. Int J Mol Sci. 2017;18: pubmed publisher
    ..Here, we review the recent advances of the relationship between autophagy and apoptosis in NSCLC, aiming to provide few insights into the discovery of novel pathogenic factors and the development of new cancer therapeutics. ..
  6. Kyrochristos I, Glantzounis G, Ziogas D, Gizas I, Schizas D, Lykoudis E, et al. From Clinical Standards to Translating Next-Generation Sequencing Research into Patient Care Improvement for Hepatobiliary and Pancreatic Cancers. Int J Mol Sci. 2017;18: pubmed publisher
    ..This review discusses the findings of available NGS studies on HBP cancers and the limitations of genome sequencing analysis to translate genome-based biomarkers and drugs into patient care in the clinic. ..
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    Cho W, Leung K. In vitro and in vivo anti-tumor effects of Astragalus membranaceus. Cancer Lett. 2007;252:43-54 pubmed
    ..Collectively, the results showed that A. membranaceus could exhibit both in vitro and in vivo anti-tumor effects, which might be achieved through activating the anti-tumor immune mechanism of the host...
  8. Cho W, Kwan C, Yau S, So P, Poon P, Au J. The role of inflammation in the pathogenesis of lung cancer. Expert Opin Ther Targets. 2011;15:1127-37 pubmed publisher
    ..Along with therapeutic benefits, immunotherapy presents the challenges of drug-related toxicities. Gene modification of immunocytokine may lower the associated toxic effects. ..
  9. Cho W, Yip T, Cheng W, Au J. Serum amyloid A is elevated in the serum of lung cancer patients with poor prognosis. Br J Cancer. 2010;102:1731-5 pubmed publisher
    ..Our study not only detected increased SAA level in the serum of lung cancer patients but also identified that elevated SAA level may be a non-invasive biomarker useful for the prediction of lung cancer prognosis. ..
  10. Cho W, Chow A, Au J. Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation. Eur J Cancer. 2009;45:2197-206 pubmed publisher
    ..Further study on these specific differentially expressed miRNAs may provide important information on peculiar tumourigenetic pathways and may identify useful biomarkers. ..
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    Cho W, Leung K. In vitro and in vivo immunomodulating and immunorestorative effects of Astragalus membranaceus. J Ethnopharmacol. 2007;113:132-41 pubmed
    ..Collectively, the results clearly showed that AI could exhibit immunomodulating and immunorestorative effects, both in vitro and in vivo...