Research Topics
| Jun MinSummaryAffiliation: Chinese Academy of Sciences Country: China Publications
| Collaborators
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Detail Information
Publications
Selective enrichment of hepatocytes from mouse embryonic stem cells with a culture system containing cholestatic serumJun Min
Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Sun Yat sen University, Guangzhou 510120, China
Acta Pharmacol Sin 28:1931-7. 2007..However, it is necessary to improve the differentiation efficiency so as to promote the clinical application. Here, we report an efficient culture system to support hepatocyte differentiation from ES cells by utilizing cholestatic serum...
[The problems and strategies of hepatic stem cells in therapeutic application for liver diseases]Jun Min
Department of Hepatobilliary Surgery, The Second Affiliated Hospital of Sun Yet-sen University, Guangzhou 510120, China
Zhonghua Gan Zang Bing Za Zhi 13:694-5. 2005
Differentiation of embryonic stem cells into hepatocytes that coexpress coagulation factors VIII and IXJun Cao
Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Sun Yat sen University, Guangzhou, China
Acta Pharmacol Sin 31:1478-86. 2010..To establish an efficient culture system to support embryonic stem (ES) cell differentiation into hepatocytes that coexpress F-VIII and F-IX...
Effects of sodium butyrate on the differentiation of pancreatic and hepatic progenitor cells from mouse embryonic stem cellsMeng Ren
Department of Endocrinology, The Second Affiliated Hospital of Sun Yat sen University, Guangzhou 510120, China
J Cell Biochem 109:236-44. 2010..This finding may facilitate the understanding of pancreatic and hepatic cell differentiation from ES cells, and provide a potential source of transplantable cells for cell-replacement therapies...
Functional distinction of rat liver natural killer cells from spleen natural killer cells under normal and acidic conditions in vitroLi Hong Lv
Department of Hepatobiliary Surgery, Sun Yat Sen University, Guangzhou, China
Hepatobiliary Pancreat Dis Int 11:285-93. 2012..This study was to investigate the differences in the morphological and functional characteristics between rat liver and spleen NK cells under normal and acidic conditions in vitro...
[MicroRNA differential expression profile during differentiation of embryonic stem cells towards hepatocytes induced by sodium butyrate]Ya jin Chen
Department of Hepatobiliary Surgery, The Second Affiliated Hospital, Sun Yat Sen University, Guangzhou 510120, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 30:469-73. 2008..To explore the expression profile of microRNAs during the course of embryonic stem cells differentiation towards hepatocytes induced by sodium butyrate...
In vitro differentiation of mouse ES cells into hepatocytes with coagulation factors VIII and IX expression profilesYing Meng
Center for Stem Cell Research, The Second Affiliated Hospital of Sun Yat sen University, Guangzhou 510120, China
Sci China C Life Sci 49:259-64. 2006..In this paper, expression of coagulation factors VIII and IX mRNA in the ES-derived cells is documented. Therefore, ES cells might be developed as substitute donor cells for the therapy of coagulation factor deficiencies...
[Study of embryonic stem cells induced to express hepatic cell functions in vitro in a pathologic niche containing cholestatic serum]Tian-Ling Fang
Hepatobillary Surgery, Center of Medical Research, The Second Affiliated Hospital, Sun Yet-sen University, Guangzhou 510120, China
Zhonghua Gan Zang Bing Za Zhi 12:726-9. 2004..CONCLUSIONS: Spontaneous or HGF-induced ESC differentiation has only limited hepatic functions expressed. A pathologic niche in vitro induces ESC to develop into hepatic lineages, with a higher level of hepatic metabolic functions...
Sodium butyrate and dexamethasone promote exocrine pancreatic gene expression in mouse embryonic stem cellsMeng Ren
Departments of Endocrinology and Hepatobiliary Surgery, The Second Affiliated Hospital of Sun Yat sen University, Guangzhou 510120, China
Acta Pharmacol Sin 30:1289-96. 2009..Here, we investigated whether sodium butyrate and glucocorticoids were conducive to the exocrine pancreatic differentiation of ES cells...
Anticancer drugs cause release of exosomes with heat shock proteins from human hepatocellular carcinoma cells that elicit effective natural killer cell antitumor responses in vitroLi Hong Lv
Department of Hepatobiliary Surgery, Sun Yat Sen Memorial Hospital, Sun Yat Sen University, 107W Yanjiang Road, Guangzhou 510120, China
J Biol Chem 287:15874-85. 2012....
[E14 mouse embryonic stem cells differentiate into hepatocyt ESC]Ying Meng
Center for Stem Cell Research, The Second Affiliated Hospital of Sun Yat-sen University, Guangzhou 510120, China
Zhonghua Gan Zang Bing Za Zhi 12:714-7. 2004..The ICG positive cells were about 85.1% in number. CONCLUSION: ESC-derived hepatic cells possess characteristics of hepatocytes, which would promise the eventual clinical use of ESC in treating damaged liver tissues...
Selection, proliferation and differentiation of bone marrow-derived liver stem cells with a culture system containing cholestatic serum in vitroYun Feng Cai
Department of Liver biliary Surgery, the First Hospital of Foshan City, 1 Dafu Nanlu, Foshan 528000, Guangdong Province, China
World J Gastroenterol 10:3308-12. 2004..To explore the feasibility of direct separation, selective proliferation and differentiation of the bone marrow-derived liver stem cells (BDLSC) from bone marrow cells with a culture system containing cholestatic serum in vitro...
RNA interference targeting Fas protects mice from fulminant hepatitisErwei Song
Center for Blood Research and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA
Nat Med 9:347-51. 2003..Silencing Fas expression with RNAi holds therapeutic promise to prevent liver injury by protecting hepatocytes from cytotoxicity...
