Affiliation: Chinese Center for Disease Control and Prevention
Xu W, Zhao J, Sun J, Yin Q, Wang Y, Jiao Y, et al
. The HEPT Analogue WPR-6 Is Active against a Broad Spectrum of Nonnucleoside Reverse Transcriptase Drug-Resistant HIV-1 Strains of Different Serotypes. Antimicrob Agents Chemother. 2015;59:4882-8 pubmed publisher
..However, to develop it as a new NNRTI, further improvement of its pharmacological properties is warranted. ..
Liu W, Feng Y, Wang C, Wang Y, Kong D, Qu S, et al
. Identification of a Novel HIV Type 1 CRF01_AE/CRF07_BC Recombinant virus in Men Who Have Sex with Men in GuangXi, China. AIDS Res Hum Retroviruses. 2018;: pubmed publisher
..The emergence of GX2016EU10 indicates that the HIV-1 epidemic among men who have sex with men in Guangxi is increasing in complexity, which poses a serious challenge to prevention and control. ..
Jiao Y, Huang Y, Li S, Li Z, Wang Y, Yin Q, et al
. [Replication kinetic properties of HIV-1 CRF_BC novel drug resistance associated mutations]. Zhonghua Yu Fang Yi Xue Za Zhi. 2015;49:436-40 pubmed
..The novel drug resistance associated mutations I132L and T139K/R can reduce the drug sensitivity to NNRTIs in subtype B and CRF07_BC, and the replication ability of CRF_07BC declined by I132L mutation. ..
Jiao Y, Wang Y, Kong D, Wang C, Xin R, Feng Y, et al
. Characterization of a New HIV-1 CRF01_AE/CRF07_BC Recombinant virus Form Men Who Have Sex with Men in Beijing, China. AIDS Res Hum Retroviruses. 2018;: pubmed publisher
Wang C, Wang Y, Kong D, Liang S, Feng Y, Ma L. Identification of a Novel HIV-1 B/C/ CRF01_AE Recombinant Isolate in Guangxi, China. AIDS Res Hum Retroviruses. 2018;: pubmed publisher
..The emergence of GX2016EU13 may suppose the complexity of the HIV-1 epidemic in high-risk sexual populations in Guangxi, China. ..
Cheng S, Wang Y, Zhang Z, Lv X, Gao G, Shao Y, et al
. Enfuvirtide-PEG conjugate: A potent HIV fusion inhibitor with improved pharmacokinetic properties. Eur J Med Chem. 2016;121:232-237 pubmed publisher
Jiao Y, Li S, Li Z, Zhang Z, Zhao J, Li L, et al
. HIV-1 transmitted drug resistance-associated mutations and mutation co-variation in HIV-1 treatment-naÃ¯ve MSM from 2011 to 2013 in Beijing, China. BMC Infect Dis. 2014;14:689 pubmed publisher
..It provides important information for understanding TDR and viral evolution among Chinese MSM, a population currently at particularly high risk of HIV transmission. ..
Ouyang Y, Yin Q, Li W, Li Z, Kong D, Wu Y, et al
. Escape from humoral immunity is associated with treatment failure in HIV-1-infected patients receiving long-term antiretroviral therapy. Sci Rep. 2017;7:6222 pubmed publisher
..These results indicate that the escape of HIV-1 from host humoral immunity may play a direct role in TF in long-term antiretroviral-experienced patients and that based on env gene sequence of the viruses in the patients. ..
Kong D, Wang Y, Wang C, Liang S, Feng Y, Shao Y, et al
. Identification of a novel HIV-1 unique recombinant form between B, CRF01_AE and CRF07_BC in men who have sex with men in Guangxi, China. AIDS Res Hum Retroviruses. 2017;: pubmed publisher
..This is the first detection of a novel HIV-1 recombinant (B/ CRF01_AE /CRF07_BC) in MSM in Guangxi. The emergence of this novel recombinant suggests the increasing genetic diversity of the HIV-1 epidemic among the MSM group in China...