Liying Ma

Summary

Affiliation: Chinese Center for Disease Control and Prevention
Country: China

Publications

  1. Xu W, Zhao J, Sun J, Yin Q, Wang Y, Jiao Y, et al. The HEPT Analogue WPR-6 Is Active against a Broad Spectrum of Nonnucleoside Reverse Transcriptase Drug-Resistant HIV-1 Strains of Different Serotypes. Antimicrob Agents Chemother. 2015;59:4882-8 pubmed publisher
    ..However, to develop it as a new NNRTI, further improvement of its pharmacological properties is warranted. ..
  2. Liu W, Feng Y, Wang C, Wang Y, Kong D, Qu S, et al. Identification of a Novel HIV Type 1 CRF01_AE/CRF07_BC Recombinant virus in Men Who Have Sex with Men in GuangXi, China. AIDS Res Hum Retroviruses. 2018;: pubmed publisher
    ..The emergence of GX2016EU10 indicates that the HIV-1 epidemic among men who have sex with men in Guangxi is increasing in complexity, which poses a serious challenge to prevention and control. ..
  3. request reprint
    Jiao Y, Huang Y, Li S, Li Z, Wang Y, Yin Q, et al. [Replication kinetic properties of HIV-1 CRF_BC novel drug resistance associated mutations]. Zhonghua Yu Fang Yi Xue Za Zhi. 2015;49:436-40 pubmed
    ..The novel drug resistance associated mutations I132L and T139K/R can reduce the drug sensitivity to NNRTIs in subtype B and CRF07_BC, and the replication ability of CRF_07BC declined by I132L mutation. ..
  4. Jiao Y, Wang Y, Kong D, Wang C, Xin R, Feng Y, et al. Characterization of a New HIV-1 CRF01_AE/CRF07_BC Recombinant virus Form Men Who Have Sex with Men in Beijing, China. AIDS Res Hum Retroviruses. 2018;: pubmed publisher
  5. Wang C, Wang Y, Kong D, Liang S, Feng Y, Ma L. Identification of a Novel HIV-1 B/C/ CRF01_AE Recombinant Isolate in Guangxi, China. AIDS Res Hum Retroviruses. 2018;: pubmed publisher
    ..The emergence of GX2016EU13 may suppose the complexity of the HIV-1 epidemic in high-risk sexual populations in Guangxi, China. ..
  6. Cheng S, Wang Y, Zhang Z, Lv X, Gao G, Shao Y, et al. Enfuvirtide-PEG conjugate: A potent HIV fusion inhibitor with improved pharmacokinetic properties. Eur J Med Chem. 2016;121:232-237 pubmed publisher
  7. Jiao Y, Li S, Li Z, Zhang Z, Zhao J, Li L, et al. HIV-1 transmitted drug resistance-associated mutations and mutation co-variation in HIV-1 treatment-naïve MSM from 2011 to 2013 in Beijing, China. BMC Infect Dis. 2014;14:689 pubmed publisher
    ..It provides important information for understanding TDR and viral evolution among Chinese MSM, a population currently at particularly high risk of HIV transmission. ..
  8. Ouyang Y, Yin Q, Li W, Li Z, Kong D, Wu Y, et al. Escape from humoral immunity is associated with treatment failure in HIV-1-infected patients receiving long-term antiretroviral therapy. Sci Rep. 2017;7:6222 pubmed publisher
    ..These results indicate that the escape of HIV-1 from host humoral immunity may play a direct role in TF in long-term antiretroviral-experienced patients and that based on env gene sequence of the viruses in the patients. ..
  9. Kong D, Wang Y, Wang C, Liang S, Feng Y, Shao Y, et al. Identification of a novel HIV-1 unique recombinant form between B, CRF01_AE and CRF07_BC in men who have sex with men in Guangxi, China. AIDS Res Hum Retroviruses. 2017;: pubmed publisher
    ..This is the first detection of a novel HIV-1 recombinant (B/ CRF01_AE /CRF07_BC) in MSM in Guangxi. The emergence of this novel recombinant suggests the increasing genetic diversity of the HIV-1 epidemic among the MSM group in China...

More Information

Publications10

  1. Sun Y, Xu W, Fan N, Sun X, Ning X, Ma L, et al. Design, synthesis and biological evaluation of (E)-3,4-dihydroxystyryl 4-acylaminophenethyl sulfone, sulfoxide derivatives as dual inhibitors of HIV-1 CCR5 and integrase. Bioorg Med Chem. 2017;25:1076-1084 pubmed publisher
    ..These data demonstrate that the structure of (E)-3,4-dihydroxystyryl sulfone and sulfoxide derivatives have the potential to derive potent dual inhibitors of HIV-1 Integrase and CCR5. ..