- Candida skin test reagent as a novel adjuvant for a human papillomavirus peptide-based therapeutic vaccineXuelian Wang
Department of Microbiology and Parasitology, College of Basic Medical Sciences, China Medical University, Shenyang, China Electronic address
Vaccine 31:5806-13. 2013..In summary, the Langerhans cell maturation effects of the vaccine were due to the peptides while the T-cell proliferative capacity was derived from Candida, and the most frequently induced cytokine was IL-12. ..
- A novel CD4 T-cell epitope described from one of the cervical cancer patients vaccinated with HPV 16 or 18 E7-pulsed dendritic cellsXuelian Wang
Department of Microbiology and Parasitology, College of Basic Medical Sciences, China Medical University, 92 Beier Road, Heping District, Shenyang, 110001, China corrected
Cancer Immunol Immunother 58:301-8. 2009..T-cell clones specific for the E7 47-70 region were isolated from one of the subjects. Further analyses revealed a novel, naturally processed, CD4 T-cell epitope, E7 58-68 (CCKCDSTLRLC), restricted by the HLA-DR17 molecule...
- Use of interferon-γ enzyme-linked immunospot assay to characterize novel T-cell epitopes of human papillomavirusXuelian Wang
Department of Microbiology and Parasitology, College of Basic Medical Sciences, China Medical University
J Vis Exp . 2012..The result demonstrated that the E6 T-cell epitope was endogenously processed. The cross-recognition of homologous T-cell epitope of other high-risk HPV types was shown. This method can also be used to describe CD4 T-cell epitopes(4)...