Guifan Sun


Affiliation: China Medical University
Country: China


  1. Li J, Duan X, Dong D, Zhang Y, Li W, Zhao L, et al. Hepatic and Nephric NRF2 Pathway Up-Regulation, an Early Antioxidant Response, in Acute Arsenic-Exposed Mice. Int J Environ Res Public Health. 2015;12:12628-42 pubmed publisher
    ..A better knowledge about the NRF2 pathway involvment in the cellular response against arsenic could help improve the strategies for reducing the cellular toxicity related to this metalloid. ..
  2. Sun G, Xu Y, Zheng Q, Xi S. Arsenicosis history and research progress in Mainland China. Kaohsiung J Med Sci. 2011;27:377-81 pubmed publisher
  3. Yang B, Fan S, Zhi X, Wang D, Li Y, Wang Y, et al. Associations of MTHFR C677T and MTRR A66G gene polymorphisms with metabolic syndrome: a case-control study in Northern China. Int J Mol Sci. 2014;15:21687-702 pubmed publisher
    ..The MTRR A66G polymorphism is not associated with MetS. However, it may exacerbate the effect of the MTHFR C677T variant alone. Further large prospective population-based studies are required to confirm our findings. ..
  4. Yang B, Fan S, Zhi X, Wang Y, Wang Y, Zheng Q, et al. Prevalence of hyperhomocysteinemia in China: a systematic review and meta-analysis. Nutrients. 2014;7:74-90 pubmed publisher
    ..In summary, the prevalence of HHcy in China is high, particularly in northern populations, the inlanders, males, and the elderly. Homocysteine-lowering strategies are necessary to reduce this highly preventable disorder. ..
  5. Li Y, Wang D, Li X, Zheng Q, Sun G. A potential synergy between incomplete arsenic methylation capacity and demographic characteristics on the risk of hypertension: findings from a cross-sectional study in an arsenic-endemic area of inner Mongolia, China. Int J Environ Res Public Health. 2015;12:3615-32 pubmed publisher
    ..The findings of present study indicated that inefficient arsenic methylation capacity was associated with hypertension and the effect might be enhanced by certain demographic factors. ..
  6. Li Y, Wang D, Xu Y, Liu B, Zheng Y, Yang B, et al. Use status and metabolism of realgar in Chinese patent medicine. J Ethnopharmacol. 2015;: pubmed publisher
  7. Fan S, Yang B, Zhi X, He M, Wang D, Wang Y, et al. Are MTHFR C677T and MTRR A66G Polymorphisms Associated with Overweight/Obesity Risk? From a Case-Control to a Meta-Analysis of 30,327 Subjects. Int J Mol Sci. 2015;16:11849-63 pubmed publisher
    ..Further large-scale population-based studies, especially for the MTRR A66G polymorphism, are still needed to confirm or refute our findings. ..
  8. Zhang Q, Wang D, Zheng Q, Zheng Y, Wang H, Xu Y, et al. Joint effects of urinary arsenic methylation capacity with potential modifiers on arsenicosis: a cross-sectional study from an endemic arsenism area in Huhhot Basin, northern China. Environ Res. 2014;132:281-9 pubmed publisher
    ..The findings of the present study suggest that a lower arsenic methylation capacity was associated with arsenicosis and that certain risk factors may enhance the risk of arsenic-induced skin lesions. ..
  9. Li Y, Ye F, Wang A, Wang D, Yang B, Zheng Q, et al. Chronic Arsenic Poisoning Probably Caused by Arsenic-Based Pesticides: Findings from an Investigation Study of a Household. Int J Environ Res Public Health. 2016;13: pubmed publisher
    ..This report elucidates the effects of arsenical compounds on the occurrence of high levels of arsenic in the environment and emphasizes the severe human health impact of arsenic exposure. ..

More Information


  1. Fan S, Yang B, Zhi X, Wang Y, Wei J, Zheng Q, et al. Interactions of Methylenetetrahydrofolate Reductase C677T Polymorphism with Environmental Factors on Hypertension Susceptibility. Int J Environ Res Public Health. 2016;13: pubmed publisher