Research Topics

Genomes and Genes


Yunbo Luo


Affiliation: China Agricultural University
Country: China


  1. Feng Y, Shao X, Huang K, Tian J, Mei X, Luo Y, et al. Mercury nanoladders: a new method for DNA amplification, signal identification and their application in the detection of Hg(ii) ions. Chem Commun (Camb). 2018;: pubmed publisher
    ..GO was used to differentiate the fluorescence generated by Hg(ii) nanoladders from a background signal. ..
  2. Li S, Xu H, Ju Z, Cao D, Zhu H, Fu D, et al. The RIN-MC Fusion of MADS-Box Transcription Factors Has Transcriptional Activity and Modulates Expression of Many Ripening Genes. Plant Physiol. 2018;176:891-909 pubmed publisher
  3. Gao W, Tian J, Huang K, Yang Z, Xu W, Luo Y. Ultrafast, universal and visual screening of dual genetically modified elements based on dual super PCR and a lateral flow biosensor. Food Chem. 2019;279:246-251 pubmed publisher
    ..This method may be useful for the ultrafast, universal and visual screening of dual GM elements (P-35s × T-nos) in GM crop lines and is expected to be of great promise for rapid GMO screening and point-of-care tests. ..
  4. Xu W, Zhu L, Shao X, Huang K, Luo Y. An electrochemical biosensor based on nucleic acids enzyme and nanochannels for detecting copper (II) ion. Biosens Bioelectron. 2018;120:168-174 pubmed publisher
    ..The developed electrochemical biosensor also displayed high selectivity for Cu2+, which could be useful for monitoring Cu2+ above ten picomole. ..
  5. Cheng N, Wang Q, Shang Y, Xu Y, Huang K, Yang Z, et al. Rapid and low-cost strategy for detecting genome-editing induced deletion: A single-copy case. Anal Chim Acta. 2018;1019:111-118 pubmed publisher
    ..To this effect, the proposed method is a rapid and low-cost solution to sample-to-answer detection of genome-editing induced deletion and shows remarkable potential in regards to international trade, transparency, and freedom of choice. ..
  6. Zuo J, Wang Y, Zhu B, Luo Y, Wang Q, Gao L. Comparative Analysis of DNA Methylation Reveals Specific Regulations on Ethylene Pathway in Tomato Fruit. Genes (Basel). 2018;9: pubmed publisher
    ..Furthermore, the relationships between DNA methylation and microRNAs (miRNAs) were also deciphered, providing basic information for the further study of DNA methylation and small RNAs involved in the ethylene pathway. ..
  7. Zuo J, Wang Y, Zhu B, Luo Y, Wang Q, Gao L. Analysis of the Coding and Non-Coding RNA Transcriptomes in Response to Bell Pepper Chilling. Int J Mol Sci. 2018;19: pubmed publisher
  8. Xu W, Cheng N, Huang K, Lin Y, Wang C, Xu Y, et al. Accurate and easy-to-use assessment of contiguous DNA methylation sites based on proportion competitive quantitative-PCR and lateral flow nucleic acid biosensor. Biosens Bioelectron. 2016;80:654-660 pubmed publisher
  9. Zhu P, Wang C, Huang K, Luo Y, Xu W. A Novel Pretreatment-Free Duplex Chamber Digital PCR Detection System for the Absolute Quantitation of GMO Samples. Int J Mol Sci. 2016;17:402 pubmed publisher
    ..In conclusion, we have provided a simple and flexible way of achieving absolute quantitation for genetically modified organism (GMO) genome samples using commercial digital PCR detection systems. ..

More Information


  1. Xu W, Wang C, Zhu P, Guo T, Xu Y, Huang K, et al. Real-time quantitative nicking endonuclease-mediated isothermal amplification with small molecular beacons. Analyst. 2016;141:2542-52 pubmed publisher
    ..This theoretical and practical basis will help us to monitor SMB-NEMA in a quantitative way. In summary, our SMB-NEMA method allows the simple, specific and sensitive assessment of isothermal DNA quantification. ..
  2. Cao D, Wang J, Ju Z, Liu Q, Li S, Tian H, et al. Regulations on growth and development in tomato cotyledon, flower and fruit via destruction of miR396 with short tandem target mimic. Plant Sci. 2016;247:1-12 pubmed publisher
    ..Overall, these results revealed novel roles of miR396 in regulating flower and fruit development, and provided a new potential way for improving tomato fruit yield. ..
  3. Li R, Zhu H, Luo Y. Understanding the Functions of Long Non-Coding RNAs through Their Higher-Order Structures. Int J Mol Sci. 2016;17: pubmed publisher
    ..The aim of this review is to provide a better understanding of lncRNA biological functions by studying them at the structural level. ..
  4. Ju Z, Wang L, Cao D, Zuo J, Zhu H, Fu D, et al. A viral satellite DNA vector-induced transcriptional gene silencing via DNA methylation of gene promoter in Nicotiana benthamiana. Virus Res. 2016;223:99-107 pubmed publisher
    ..Overall, these results demonstrated that the viral satellite DNA vector could be used as an effective VITGS vector to study DNA methylation in plant genomes. ..
  5. Xu W, Tian J, Shao X, Zhu L, Huang K, Luo Y. A rapid and visual aptasensor for Lipopolysaccharides detection based on the bulb-like triplex turn-on switch coupled with HCR-HRP nanostructures. Biosens Bioelectron. 2017;89:795-801 pubmed publisher
  6. Zhai B, Zhang C, Sheng Y, Zhao C, He X, Xu W, et al. Hypoglycemic and hypolipidemic effect of S-allyl-cysteine sulfoxide (alliin) in DIO mice. Sci Rep. 2018;8:3527 pubmed publisher
    ..From above, we conclude that alliin has nutraceutical or even medicinal potential in prevention of diabetes and lipid metabolic disorders. ..
  7. Li S, Li K, Ju Z, Cao D, Fu D, Zhu H, et al. Genome-wide analysis of tomato NF-Y factors and their role in fruit ripening. BMC Genomics. 2016;17:36 pubmed publisher
    ..The results indicated that five NF-Y transcription factors play roles in tomato fruit ripening. This information provides a platform for further investigation of their biological functions. ..