Affiliation: China Agricultural University
Pu J, Wang S, Yin Y, Zhang G, Carter R, Wang J, et al
. Evolution of the H9N2 influenza genotype that facilitated the genesis of the novel H7N9 virus. Proc Natl Acad Sci U S A. 2015;112:548-53 pubmed publisher
..The prevalence and variation of H9N2 influenza virus in farmed poultry could provide an important early warning of the emergence of novel reassortants with pandemic potential. ..
Liu L, Wang T, Wang M, Tong Q, Sun Y, Pu J, et al
. Recombinant turkey herpesvirus expressing H9 hemagglutinin providing protection against H9N2 avian influenza. Virology. 2019;529:7-15 pubmed publisher
..In the challenge study, no chicken shed H9N2 virus from oropharynx and cloaca, and no H9N2 virus was found in viscera in vaccination groups. The result suggests that rHVT-H9 provides effective protection against H9N2 AIV in chickens. ..
Kong W, Liu L, Wang Y, He Q, Wu S, Qin Z, et al
. C-terminal elongation of NS1 of H9N2 influenza virus induces a high level of inflammatory cytokines and increases transmission. J Gen Virol. 2015;96:259-68 pubmed publisher
..These findings suggest that the NS1 extension conferred a gain of fitness to some extent. ..
Wang M, Wei Y, Pu J, Bing G, Sun Y, Sun H, et al
. Cross- immunity of a H9N2 live attenuated influenza vaccine against H5N2 highly pathogenic avian influenza virus in chickens. Vet Microbiol. 2018;220:57-66 pubmed publisher
..The cross immunity was partly attributed to LAIV activated H5N2-cross-reactive T cells and partly attributed to cross-binding IgGs against NP. ..
Zhang X, Shen Y, Du L, Wang R, Jiang B, Sun H, et al
. Serological survey of canine H3N2, pandemic H1N1/09, and human seasonal H3N2 influenza viruses in cats in northern China, 2010-2014. Virol J. 2015;12:50 pubmed publisher
..3%), and then declined continuously thereafter. Cats older than 10Â years were most commonly seropositive for the H1N1/09 virus. Our findings emphasize the need for continuous surveillance of influenza viruses in cats in China. ..
Sun H, Pu J, Hu J, Liu L, Xu G, Gao G, et al
. Characterization of clade 126.96.36.199 highly pathogenic H5 avian influenza viruses in ducks and chickens. Vet Microbiol. 2016;182:116-22 pubmed publisher
..Antigenicity analysis revealed that the current vaccines that are widely used in China may fail to confer protection against the H5 reassortants. ..
Liu J, Shi W, Wu Q, Guo Y. [Sequence analysis of NS1 gene of some H9N2 subtype influenza viruses isolated from chickens in China]. Wei Sheng Wu Xue Bao. 2003;43:547-53 pubmed
Pu J, Sun H, Qu Y, Wang C, Gao W, Zhu J, et al
. M Gene Reassortment in H9N2 Influenza Virus Promotes Early Infection and Replication: Contribution to Rising Virus Prevalence in Chickens in China. J Virol. 2017;91: pubmed publisher
Sun H, Pu J, Wei Y, Sun Y, Hu J, Liu L, et al
. Highly Pathogenic Avian Influenza H5N6 Viruses Exhibit Enhanced Affinity for Human Type Sialic Acid Receptor and In-Contact Transmission in Model Ferrets. J Virol. 2016;90:6235-6243 pubmed publisher
..These findings suggest that the threat of avian H5N6 viruses to humans should not be ignored. ..